International Journal of Nanomedicine, Volume 19, Issue (2024)

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International Journal of Nanomedicine, Volume 19, Issue (2024)

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ORIGINAL RESEARCH

Article
ULK1 Mediated Autophagy-Promoting Effects of Rutin-Loaded Chitosan Nanoparticles Contribute to the Activation of NF-κB Signaling Besides Inhibiting EMT in Hep3B Hepatoma Cells
Peng Wu, Xiaoyong Wang, Min Yin, Wenjie Zhu, Zheng Chen, Yang Zhang, Ziyu Jiang, Longqing Shi & Qiang Zhu
Pages: 4465-4493
Published online: 18 May 2024
AbstractforULK1 Mediated Autophagy-Promoting Effects of Rutin-Loaded Chitosan Nanoparticles Contribute to the Activation of NF-κB Signaling Besides Inhibiting EMT in Hep3B Hepatoma Cells | Full Text | References | PDF (7.4 MB) | EPUB
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Article
Biodynamer Nano-Complexes and -Emulsions for Peptide and Protein Drug Delivery
Yun Liu, Timo Hamm, Thomas Ralf Eichinger, Walter Kamm, Heike Andrea Wieland, Brigitta Loretz, Anna KH Hirsch, Sangeun Lee & Claus-Michael Lehr
Pages: 4429-4449
Published online: 18 May 2024
AbstractforBiodynamer Nano-Complexes and -Emulsions for Peptide and Protein Drug Delivery | Full Text | References | PDF (9.5 MB) | EPUB
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Article
Administration of Liposomal-Based Pde3b Gene Therapy Protects Mice Against Collagen-Induced Rheumatoid Arthritis via Modulating Macrophage Polarization
Longmin Chen, Qing Zhou, Xun Fang, Qianqian Xu, Yuan Zou & Jing Zhang
Pages: 4411-4427
Published online: 17 May 2024
AbstractforAdministration of Liposomal-Based Pde3b Gene Therapy Protects Mice Against Collagen-Induced Rheumatoid Arthritis via Modulating Macrophage Polarization | Full Text | References | PDF (12.6 MB) | EPUB
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REVIEW

Review
Advances in Engineered Nanoparticles for the Treatment of Ischemic Stroke by Enhancing Angiogenesis
Guangtian Wang, Zhihui Li, Gongchen Wang, Qixu Sun, Peng Lin, Qian Wang, Huishu Zhang, Yanyan Wang, Tongshuai Zhang, Feiyun Cui & Zhaohua Zhong
Pages: 4377-4409
Published online: 17 May 2024
AbstractforAdvances in Engineered Nanoparticles for the Treatment of Ischemic Stroke by Enhancing Angiogenesis | Full Text | References | PDF (14.5 MB) | EPUB
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Open Access
Review
Stem Cell-Derived Extracellular Vesicles: Promising Therapeutic Opportunities for Diabetic Wound Healing
Boyu Zhang, Yajun Bi, Kang Wang, Xingjun Guo, Zeming Liu, Jia Li & Min Wu
Pages: 4357-4375
Published online: 17 May 2024
AbstractforStem Cell-Derived Extracellular Vesicles: Promising Therapeutic Opportunities for Diabetic Wound Healing | Full Text | References | PDF (4.7 MB) | EPUB
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ORIGINAL RESEARCH

Article
Polyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer
Cheng Wang, Jiaoyang Pan, Shaoqing Chen, Lin Qiu, Huaanzi Hu, Li Ji, Jianhao Wang, Wenjia Liu & Xinye Ni
Pages: 4339-4356
Published online: 17 May 2024
AbstractforPolyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer | Full Text | References | PDF (13 MB) | EPUB
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Article
Key Transdermal Patch Using Cannabidiol-Loaded Nanocarriers with Better Pharmacokinetics in vivo
Po-Cheng Chu, Man-Hua Liao, Mao-Gu Liu, Cun-Zhao Li & Ping-Shan Lai
Pages: 4321-4337
Published online: 16 May 2024
AbstractforKey Transdermal Patch Using Cannabidiol-Loaded Nanocarriers with Better Pharmacokinetics in vivo | Full Text | References | PDF (5 MB) | EPUB
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Open Access

LETTER

Letter to the Editor
Response to Article “Oriented Graphene Oxide Scaffold Promotes Nerve Regeneration in vitro and in vivo” [Letter]
Novrynda Eko Satriawan & Ariyani Noviantari
Pages: 4319-4320
Published online: 15 May 2024
CitationforResponse to Article “Oriented Graphene Oxide Scaffold Promotes Nerve Regeneration in vitro and in vivo” [Letter] | Full Text | References | PDF (281.8 KB) | EPUB
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ORIGINAL RESEARCH

Article
Biosynthesis of Nanoparticles with Green Tea for Inhibition of β-Amyloid Fibrillation Coupled with Ligands Analysis
Mai Zhang, Yan Li, Chunli Han, Shiying Chu, Peng Yu & Wenbo Cheng
Pages: 4299-4317
Published online: 14 May 2024
AbstractforBiosynthesis of Nanoparticles with Green Tea for Inhibition of β-Amyloid Fibrillation Coupled with Ligands Analysis | Full Text | References | PDF (6.5 MB) | EPUB
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CORRIGENDUM

Correction
Design and Self-Assembly of Peptide-Copolymer Conjugates into Nanoparticle Hydrogel for Wound Healing in Diabetes [Corrigendum]
Pages: 4297-4298
Published online: 16 May 2024
CitationforDesign and Self-Assembly of Peptide-Copolymer Conjugates into Nanoparticle Hydrogel for Wound Healing in Diabetes [Corrigendum] | Full Text | PDF (2.6 MB) | EPUB
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REVIEW

Review
Neural Stem Cell-Derived Small Extracellular Vesicles: key Players in Ischemic Stroke Therapy – A Comprehensive Literature Review
Zhihan Zhu, Qiankun Zhang, Jia Feng, Sonia Zebaze Dongmo, Qianqian Zhang, Songze Huang, Xiaowen Liu, Guilong Zhang & Lukui Chen
Pages: 4279-4295
Published online: 13 May 2024
AbstractforNeural Stem Cell-Derived Small Extracellular Vesicles: key Players in Ischemic Stroke Therapy – A Comprehensive Literature Review | Full Text | References | PDF (5.5 MB) | EPUB
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ORIGINAL RESEARCH

Article
Combined Ferritin Nanocarriers with ICG for Effective Phototherapy Against Breast Cancer
Leopoldo Sitia, Paola Saccomandi, Leonardo Bianchi, Marta Sevieri, Cristina Sottani, Raffaele Allevi, Elena Grignani, Serena Mazzucchelli & Fabio Corsi
Pages: 4263-4278
Published online: 15 May 2024
AbstractforCombined Ferritin Nanocarriers with ICG for Effective Phototherapy Against Breast Cancer | Full Text | References | PDF (8.9 MB) | EPUB
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Article
Single Atom-Dispersed Silver Incorporated in ZIF-8-Derived Porous Carbon for Enhanced Photothermal Activity and Antibacterial Activities
Yutong Zheng, Xiaoyi Cai, Gui Chen, Dexuan Xiang, Wei Shi, Jianliang Shen & Bailin Xiang
Pages: 4253-4261
Published online: 15 May 2024
AbstractforSingle Atom-Dispersed Silver Incorporated in ZIF-8-Derived Porous Carbon for Enhanced Photothermal Activity and Antibacterial Activities | Full Text | References | PDF (5.5 MB) | EPUB
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Article
Strategies for Improved pDNA Loading and Protection Using Cationic and Neutral LNPs with Industrial Scalability Potential Using Microfluidic Technology
Ilaria Ottonelli, Elisa Adani, Andrea Bighinati, Sabrina Cuoghi, Giovanni Tosi, Maria Angela Vandelli, Barbara Ruozi, Valeria Marigo & Jason Thomas Duskey
Pages: 4235-4251
Published online: 15 May 2024
AbstractforStrategies for Improved pDNA Loading and Protection Using Cationic and Neutral LNPs with Industrial Scalability Potential Using Microfluidic Technology | Full Text | References | PDF (8 MB) | EPUB
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Article
Combined ROS Sensitive Folate Receptor Targeted Micellar Formulations of Curcumin Effective Against Rheumatoid Arthritis in Rat Model
Yuanyuan Wang, Ruibo Guo, Ming Zou, Lingling Jiang, Liang Kong, Sen Zhao, Xuan Zhang, Wei Wang & Baoli Xu
Pages: 4217-4234
Published online: 13 May 2024
AbstractforCombined ROS Sensitive Folate Receptor Targeted Micellar Formulations of Curcumin Effective Against Rheumatoid Arthritis in Rat Model | Full Text | References | PDF (16.1 MB) | EPUB
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Article
Synergistic Effect of Layered Double Hydroxides Nanodosage Form to Induce Apoptosis and Ferroptosis in Breast Cancer
Siyan Pang, Chenchen Geng, Zihan Fan, Min Hou, Huilan Mao, Shuang Tao, Jing Wang, Yulun Wu, Ke Wei, Yunhao Li, Liuyang Yan, Qingling Yang, Changjie Chen & Wenrui Wang
Pages: 4199-4215
Published online: 13 May 2024
AbstractforSynergistic Effect of Layered Double Hydroxides Nanodosage Form to Induce Apoptosis and Ferroptosis in Breast Cancer | Full Text | References | PDF (12 MB) | EPUB
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Article
Size-Optimized Layered Double Hydroxide Nanoparticles Promote Neural Progenitor Cells Differentiation of Embryonic Stem Cells Through the Regulation of M6A Methylation
Yuxin Bai, Yanjing Zhu, Xiaolie He, Ruiqi Huang, Xu Xu, Li Yang, Zhaojie Wang & Rongrong Zhu
Pages: 4181-4197
Published online: 13 May 2024
AbstractforSize-Optimized Layered Double Hydroxide Nanoparticles Promote Neural Progenitor Cells Differentiation of Embryonic Stem Cells Through the Regulation of M6A Methylation | Full Text | References | PDF (15.3 MB) | EPUB
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Article
Multimodal Imaging-Guided Synergistic Photodynamic Therapy Using Carbonized Zn/Co Metal-Organic Framework Loaded with Cytotoxin Against Liver Cancer
Jingmei Huang, Lianshan Guo, Xiaoxiao Huang, Xiaoping Yu, Liqiao Lin, Xinlin Jiang, Zhihao Bai & Zhengzhao Li
Pages: 4163-4180
Published online: 11 May 2024
AbstractforMultimodal Imaging-Guided Synergistic Photodynamic Therapy Using Carbonized Zn/Co Metal-Organic Framework Loaded with Cytotoxin Against Liver Cancer | Full Text | References | PDF (16.2 MB) | EPUB
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Article
An Eco-Friendly Synthesis Approach for Enhanced Photocatalytic and Antibacterial Properties of Copper Oxide Nanoparticles Using Coelastrella terrestris Algal Extract
Manisha Khandelwal, Sunita Choudhary, Harish, Ashok Kumawat, Kamakhya Prakash Misra, Yogeshwari Vyas, Bhavya Singh, Devendra Singh Rathore, Kanchan Soni, Ashima Bagaria & Rama Kanwar Khangarot
Pages: 4137-4162
Published online: 10 May 2024
AbstractforAn Eco-Friendly Synthesis Approach for Enhanced Photocatalytic and Antibacterial Properties of Copper Oxide Nanoparticles Using Coelastrella terrestris Algal Extract | Full Text | References | PDF (8.9 MB) | EPUB
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Article
Gold Nanorod-Loaded Nano-Contrast Agent with Composite Shell-Core Structure for Ultrasonic/Photothermal Imaging-Guided Therapy in Ischemic Muscle Disorders
Xiaoyi Tang, Yijia Liu, Mengxin Zhao, Lei He, Jiahao Guo, Tian Wang, Wei Li & Jiaqi Zhao
Pages: 4121-4136
Published online: 07 May 2024
AbstractforGold Nanorod-Loaded Nano-Contrast Agent with Composite Shell-Core Structure for Ultrasonic/Photothermal Imaging-Guided Therapy in Ischemic Muscle Disorders | Full Text | References | PDF (9.5 MB) | EPUB
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Article
Long-Term Accumulation, Biological Effects and Toxicity of BSA-Coated Gold Nanoparticles in the Mouse Liver, Spleen, and Kidneys
Kristina Jakic, Michal Selc, Filip Razga, Veronika Nemethova, Petra Mazancova, Filip Havel, Michal Sramek, Monika Zarska, Jan Proska, Vlasta Masanova, Iveta Uhnakova, Peter Makovicky, Marta Novotova, Vit Vykoukal & Andrea Babelova
Pages: 4103-4120
Published online: 07 May 2024
AbstractforLong-Term Accumulation, Biological Effects and Toxicity of BSA-Coated Gold Nanoparticles in the Mouse Liver, Spleen, and Kidneys | Full Text | References | PDF (14.6 MB) | EPUB
  • 61 Views
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Article
Injectable Hydrogel Loaded with CDs and FTY720 Combined with Neural Stem Cells for the Treatment of Spinal Cord Injury
Zhiping Qi, Su Pan, Xiaoyu Yang, Renfeng Zhang, Cheng Qin, Hongye Yan, Longchuan Zhu & Weijian Kong
Pages: 4081-4101
Published online: 08 May 2024
AbstractforInjectable Hydrogel Loaded with CDs and FTY720 Combined with Neural Stem Cells for the Treatment of Spinal Cord Injury | Full Text | References | PDF (27.2 MB) | EPUB
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Article
Nanosuspension-Loaded Dissolving Microneedle Patches for Enhanced Transdermal Delivery of a Highly Lipophilic Cannabidiol
Aguo Cheng, Suohui Zhang, Fanda Meng, Mengzhen Xing, Han Liu, Guozhong Yang & Yunhua Gao
Pages: 4061-4079
Published online: 06 May 2024
AbstractforNanosuspension-Loaded Dissolving Microneedle Patches for Enhanced Transdermal Delivery of a Highly Lipophilic Cannabidiol | Full Text | References | PDF (8.1 MB) | EPUB
  • 60 Views
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Article
Antioxidant Carbon Dots Nanozyme Loaded in Thermosensitive in situ Hydrogel System for Efficient Dry Eye Disease Treatment
Wei Wei, Haili Cao, Di Shen, Xiyu Sun, Zhenzhen Jia & Mingzhen Zhang
Pages: 4045-4060
Published online: 06 May 2024
AbstractforAntioxidant Carbon Dots Nanozyme Loaded in Thermosensitive in situ Hydrogel System for Efficient Dry Eye Disease Treatment | Full Text | References | PDF (11 MB) | EPUB
  • 43 Views
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CORRIGENDUM

Correction
Potential Efficacy of Herbal Medicine-Derived Carbon Dots in the Treatment of Diseases: From Mechanism to Clinic [Corrigendum]
Pages: 4043-4044
Published online: 06 May 2024
CitationforPotential Efficacy of Herbal Medicine-Derived Carbon Dots in the Treatment of Diseases: From Mechanism to Clinic [Corrigendum] | Full Text | PDF (737.5 KB) | EPUB
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RETRACTION

Retraction
The Effect of Dual-Functional Hyaluronic Acid-Vitamin E Succinate Micelles on Targeting Delivery of Doxorubicin [Retraction]
Pages: 4041-4042
Published online: 06 May 2024
CitationforThe Effect of Dual-Functional Hyaluronic Acid-Vitamin E Succinate Micelles on Targeting Delivery of Doxorubicin [Retraction] | Full Text | PDF (239.8 KB) | EPUB
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REVIEW

Review
Breaking Barriers: Nanomedicine-Based Drug Delivery for Cataract Treatment
Yilin Chen, Zi Ye, Haixu Chen & Zhaohui Li
Pages: 4021-4040
Published online: 06 May 2024
AbstractforBreaking Barriers: Nanomedicine-Based Drug Delivery for Cataract Treatment | Full Text | References | PDF (5.7 MB) | EPUB
  • 38 Views
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ORIGINAL RESEARCH

Article
Staphylococcus Aureus Membrane Vesicles Kill Tumor Cells Through a Caspase-1-Dependent Pyroptosis Pathway
Mengyang Li, Yuting Wang, He Liu, Xiaonan Huang, Huagang Peng, Yi Yang, Zhen Hu, Jianxiong Dou, Chuan Xiao, Juan Chen, Weilong Shang & Xiancai Rao
Pages: 4007-4019
Published online: 06 May 2024
AbstractforStaphylococcus Aureus Membrane Vesicles Kill Tumor Cells Through a Caspase-1-Dependent Pyroptosis Pathway | Full Text | References | PDF (5.6 MB) | EPUB
  • 24 Views
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Article
Innovative Vancomycin-Loaded Hydrogel-Based Systems – New Opportunities for the Antibiotic Therapy
Aleksandra Florczyk, Aleksandra Krajcer, Kinga Wójcik & Joanna Lewandowska-Łańcucka
Pages: 3991-4005
Published online: 03 May 2024
AbstractforInnovative Vancomycin-Loaded Hydrogel-Based Systems – New Opportunities for the Antibiotic Therapy | Full Text | References | PDF (6.9 MB) | EPUB
  • 30 Views
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REVIEW

Review
Chasing Graphene-Based Anticancer Drugs: Where are We Now on the Biomedical Graphene Roadmap?
Katarzyna Uzdrowska, Narcyz Knap, Jacek Gulczynski, Alicja Kuban-Jankowska, Wiktoria Struck-Lewicka, Michal J Markuszewski, Tomasz Bączek, Ewa Izycka-Swieszewska & Magdalena Gorska-Ponikowska
Pages: 3973-3989
Published online: 03 May 2024
AbstractforChasing Graphene-Based Anticancer Drugs: Where are We Now on the Biomedical Graphene Roadmap? | Full Text | References | PDF (2.2 MB) | EPUB
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ORIGINAL RESEARCH

Article
A Unique Approach: Biomimetic Graphdiyne-Based Nanoplatform to Treat Prostate Cancer by Combining Cuproptosis and Enhanced Chemodynamic Therapy
Wenjie Xie, Yixun Zhang, Qianfeng Xu, Guowei Zhong, Jundong Lin, Huichan He, Qiuling Du, Huijing Tan, Muqi Chen, Zhenjie Wu, Yulin Deng, Zhaodong Han, Jianming Lu, Jianheng Ye, Fen Zou, Yangjia Zhuo & Weide Zhong
Pages: 3957-3972
Published online: 01 May 2024
AbstractforA Unique Approach: Biomimetic Graphdiyne-Based Nanoplatform to Treat Prostate Cancer by Combining Cuproptosis and Enhanced Chemodynamic Therapy | Full Text | References | PDF (9.4 MB) | EPUB
  • 26 Views
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REVIEW

Review
Innovative Diagnosis and Therapeutic Modalities: Engineered Exosomes in Autoimmune Disease
Yuli Ji, Liangyu Mi, Miaomiao Zhao, Xiaoyao He, Yuting Hu, Yanan Gao, Chengliang Yin & Ke Xu
Pages: 3943-3956
Published online: 01 May 2024
AbstractforInnovative Diagnosis and Therapeutic Modalities: Engineered Exosomes in Autoimmune Disease | Full Text | References | PDF (3.2 MB) | EPUB
  • 99 Views
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Review
Evolving Tumor Characteristics and Smart Nanodrugs for Tumor Immunotherapy
Wenshe Sun, Shaowei Xie, Shi Feng Liu, Xiaokun Hu & Dongming Xing
Pages: 3919-3942
Published online: 30 Apr 2024
AbstractforEvolving Tumor Characteristics and Smart Nanodrugs for Tumor Immunotherapy | Full Text | References | PDF (6.3 MB) | EPUB
  • 71 Views
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ORIGINAL RESEARCH

Article
Nanoformulation of the Broad-Spectrum Hydrophobic Antiviral Vacuolar ATPase Inhibitor Diphyllin in Human Recombinant H-ferritin
Michaela Vojnikova, Martina Sukupova, Michal Stefanik, Petra Strakova, Jan Haviernik, Katerina Kapolkova, Eliska Gruberova, Klara Raskova, Hana Michalkova, Pavel Svec, Marie Peskova Kudlickova, Ivana Huvarova, Daniel Ruzek, Jiri Salat, Vladimir Pekarik, Ludek Eyer & Zbynek Heger
Pages: 3907-3917
Published online: 30 Apr 2024
AbstractforNanoformulation of the Broad-Spectrum Hydrophobic Antiviral Vacuolar ATPase Inhibitor Diphyllin in Human Recombinant H-ferritin | Full Text | References | PDF (5.6 MB) | EPUB
  • 74 Views
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Article
Green Synthesis and Characterization of Silver Nanoparticles Using Moringa Peregrina and Their Toxicity on MCF-7 and Caco-2 Human Cancer Cells
Khaled Saeed Yousef Al Baloushi, Annadurai Senthilkumar, Karthishwaran Kandhan, Radhakrishnan Subramanian, Jaleel Kizhakkayil, Tholkappiyan Ramachandran, Safa Shehab, Shyam Sreedhara Kurup, Mohammed Abdul Muhsen Alyafei, Ayesha Salem Al Dhaheri & Abdul Jaleel
Pages: 3891-3905
Published online: 01 May 2024
AbstractforGreen Synthesis and Characterization of Silver Nanoparticles Using Moringa Peregrina and Their Toxicity on MCF-7 and Caco-2 Human Cancer Cells | Full Text | References | PDF (7.2 MB) | EPUB
  • 100 Views
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Article
Enzyme-Linked Lipid Nanocarriers for Coping Pseudomonal Pulmonary Infection. Would Nanocarriers Complement Biofilm Disruption or Pave Its Road?
Noha Nafee, Dina M Gaber, Alaa Abouelfetouh, Mustafa Alseqely, Martin Empting & Marc Schneider
Pages: 3861-3890
Published online: 28 Apr 2024
AbstractforEnzyme-Linked Lipid Nanocarriers for Coping Pseudomonal Pulmonary Infection. Would Nanocarriers Complement Biofilm Disruption or Pave Its Road? | Full Text | References | PDF (17.5 MB) | EPUB
  • 74 Views
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Article
Acidic Environment-Responsive Metal Organic Framework-Mediated Dihydroartemisinin Delivery for Triggering Production of Reactive Oxygen Species in Drug-Resistant Lung Cancer
Xiaojie Yan, Xueying Zhao, Mingde Fan, Wenfu Zheng, Guanxiong Zhu, Bin Li & Le Wang
Pages: 3847-3859
Published online: 29 Apr 2024
AbstractforAcidic Environment-Responsive Metal Organic Framework-Mediated Dihydroartemisinin Delivery for Triggering Production of Reactive Oxygen Species in Drug-Resistant Lung Cancer | Full Text | References | PDF (8 MB) | EPUB
  • 76 Views
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Article
Nanoparticle/Engineered Bacteria Based Triple-Strategy Delivery System for Enhanced Hepatocellular Carcinoma Cancer Therapy
Meiyang Yang, Weijun Chen, Dhanu Gupta, Congjin Mei, Yang Yang, Bingke Zhao, Lipeng Qiu & Jinghua Chen
Pages: 3827-3846
Published online: 29 Apr 2024
AbstractforNanoparticle/Engineered Bacteria Based Triple-Strategy Delivery System for Enhanced Hepatocellular Carcinoma Cancer Therapy | Full Text | References | PDF (16.9 MB) | EPUB
  • 79 Views
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REVIEW

Review
Targeting Telomere Dynamics as an Effective Approach for the Development of Cancer Therapeutics
Hong-yu Tao, Chun-yan Zhao, Ying Wang, Wei-jin Sheng & Yong-su Zhen
Pages: 3805-3825
Published online: 30 Apr 2024
AbstractforTargeting Telomere Dynamics as an Effective Approach for the Development of Cancer Therapeutics | Full Text | References | PDF (3.3 MB) | EPUB
  • 81 Views
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Review
Advancing Tissue Damage Repair in Geriatric Diseases: Prospects of Combining Stem Cell-Derived Exosomes with Hydrogels
Ling Shi, Yunjun Zhou, Yongkui Yin, Jin Zhang, Kaiyuan Chen, Sen Liu, Peijian Chen, Hua Jiang, Jieting Liu & Yan Wu
Pages: 3773-3804
Published online: 29 Apr 2024
AbstractforAdvancing Tissue Damage Repair in Geriatric Diseases: Prospects of Combining Stem Cell-Derived Exosomes with Hydrogels | Full Text | References | PDF (12.4 MB) | EPUB
  • 85 Views
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ORIGINAL RESEARCH

Article
Oral Delivery of Photopolymerizable Nanogels Loaded with Gemcitabine for Pancreatic Cancer Therapy: Formulation Design, and in vitro and in vivo Evaluations
Adi Yugatama, Ya-Lin Huang, Ming-Jen Hsu, Jia-Pei Lin, Fang-Ching Chao, Jenny KW Lam & Chien-Ming Hsieh
Pages: 3753-3772
Published online: 24 Apr 2024
AbstractforOral Delivery of Photopolymerizable Nanogels Loaded with Gemcitabine for Pancreatic Cancer Therapy: Formulation Design, and in vitro and in vivo Evaluations | Full Text | References | PDF (11.9 MB) | EPUB
  • 127 Views
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Article
Self-Amplified pH/ROS Dual-Responsive Co-Delivery Nano-System with Chemo-Photodynamic Combination Therapy in Hepatic Carcinoma Treatment
Yu Huang, Shuyang Wu, Jingjing Li, Chenglin He, Yanfen Cheng, Nan Li, Yitao Wang, Yihan Wu & Jinming Zhang
Pages: 3737-3751
Published online: 24 Apr 2024
AbstractforSelf-Amplified pH/ROS Dual-Responsive Co-Delivery Nano-System with Chemo-Photodynamic Combination Therapy in Hepatic Carcinoma Treatment | Full Text | References | PDF (12.8 MB) | EPUB
  • 57 Views
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REVIEW

Review
Innovations in Breaking Barriers: Liposomes as Near-Perfect Drug Carriers in Ischemic Stroke Therapy
Qiankun Zhang, Songze Huang, Xiaowen Liu, Wei Wang, Zhihan Zhu & Lukui Chen
Pages: 3715-3735
Published online: 23 Apr 2024
AbstractforInnovations in Breaking Barriers: Liposomes as Near-Perfect Drug Carriers in Ischemic Stroke Therapy | Full Text | References | PDF (8.3 MB) | EPUB
  • 94 Views
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ORIGINAL RESEARCH

Article
PDADMAC/Alginate-Coated Gold Nanorod For Eradication of Staphylococcus Aureus Biofilms
Malarmugila Manimaran, Yin Yin Teo, James Chen Yong Kah, Adilet Beishenaliev, Yean Leng Loke, Yiing Yee Foo, Shiow-Fern Ng, Chin Fei Chee, Sek Peng Chin, Farid Nazer Faruqu, Chia-Yu Chang, Misni Misran, Lip Yong Chung, Bey Fen Leo, Shih-Hwa Chiou, Chia-Ching Chang, Sun Tee Tay & Lik Voon Kiew
Pages: 3697-3714
Published online: 23 Apr 2024
AbstractforPDADMAC/Alginate-Coated Gold Nanorod For Eradication of Staphylococcus Aureus Biofilms | Full Text | References | PDF (10.1 MB) | EPUB
  • 72 Views
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REVIEW

Review
Bladder Cancer in Exosomal Perspective: Unraveling New Regulatory Mechanisms
Cong Yin, Cen Liufu, Tao Zhu, Shuai Ye, Jiahao Jiang, Mingxia Wang, Yan Wang & Bentao Shi
Pages: 3677-3695
Published online: 22 Apr 2024
AbstractforBladder Cancer in Exosomal Perspective: Unraveling New Regulatory Mechanisms | Full Text | References | PDF (7.3 MB) | EPUB
  • 34 Views
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Review
The Landscape of Exosomes Biogenesis to Clinical Applications
Haitham Al-Madhagi
Pages: 3657-3675
Published online: 22 Apr 2024
AbstractforThe Landscape of Exosomes Biogenesis to Clinical Applications | Full Text | References | PDF (5.6 MB) | EPUB
  • 98 Views
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Review
Macrophage-Targeting DNA Nanomaterials: A Future Direction of Biological Therapy
Yu-Chi Tu, Yu-Mei Wang & Li-Jun Yao
Pages: 3641-3655
Published online: 22 Apr 2024
AbstractforMacrophage-Targeting DNA Nanomaterials: A Future Direction of Biological Therapy | Full Text | References | PDF (5.3 MB) | EPUB
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ORIGINAL RESEARCH

Article
EGFR Targeting of Liposomal Doxorubicin Improves Recognition and Suppression of Non-Small Cell Lung Cancer
Ernest Moles, David W Chang, Friederike M Mansfeld, Alastair Duly, Kathleen Kimpton, Amy Logan, Christopher B Howard, Kristofer J Thurecht & Maria Kavallaris
Pages: 3623-3639
Published online: 20 Apr 2024
AbstractforEGFR Targeting of Liposomal Doxorubicin Improves Recognition and Suppression of Non-Small Cell Lung Cancer | Full Text | References | PDF (10.9 MB) | EPUB
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Article
Novel Carbon Dots Derived from Moutan Cortex Significantly Improve the Solubility and Bioavailability of Mangiferin
Chuihao Kong, Kaidi Wang, Lei Sun, Hongsu Zhao, Tongsheng Wang, Wuxi Zhou, Deling Wu & Fengqing Xu
Pages: 3611-3622
Published online: 20 Apr 2024
AbstractforNovel Carbon Dots Derived from Moutan Cortex Significantly Improve the Solubility and Bioavailability of Mangiferin | Full Text | References | PDF (6.3 MB) | EPUB
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CORRIGENDUM

Correction
A TA/Cu2+ Nanoparticle Enhanced Carboxymethyl Chitosan-Based Hydrogel Dressing with Antioxidant Properties and Promoting Wound Healing [Corrigendum]
Pages: 3609-3610
Published online: 19 Apr 2024
CitationforA TA/Cu2+ Nanoparticle Enhanced Carboxymethyl Chitosan-Based Hydrogel Dressing with Antioxidant Properties and Promoting Wound Healing [Corrigendum] | Full Text | PDF (2.8 MB) | EPUB
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RETRACTION

Retraction
Nanovaccine Confers Dual Protection Against Influenza a Virus and Porcine Circovirus Type 2 [Retraction]
Pages: 3607-3608
Published online: 18 Apr 2024
CitationforNanovaccine Confers Dual Protection Against Influenza a Virus and Porcine Circovirus Type 2 [Retraction] | Full Text | PDF (239.1 KB) | EPUB
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ORIGINAL RESEARCH

Article
Regulating Tumor-Associated Macrophage Polarization by Cyclodextrin-Modified PLGA Nanoparticles Loaded with R848 for Treating Colon Cancer
Haohua Yuan, Huan Gui, Shuanghui Chen, Lan Zhu, Chenglv Wang, Qianyu Jing, Hang Lv, Quan Wan, Shuyi Wang, Shengwen Zhou, Xiaodong Ren, Yingjie Nie & Linzhao Li
Pages: 3589-3605
Published online: 16 Apr 2024
AbstractforRegulating Tumor-Associated Macrophage Polarization by Cyclodextrin-Modified PLGA Nanoparticles Loaded with R848 for Treating Colon Cancer | Full Text | References | PDF (10 MB) | EPUB
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Article
A TSHR-Targeting Aptamer in Monocytes Correlating with Clinical Activity in TAO
Jiamin Cao, Feng Zhang, Haiyan Chen, Bingxuan Wu, Jiayang Yin, Changci Chenzhao & Wei Xiong
Pages: 3577-3588
Published online: 16 Apr 2024
AbstractforA TSHR-Targeting Aptamer in Monocytes Correlating with Clinical Activity in TAO | Full Text | References | PDF (6.7 MB) | EPUB
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Article
HucMSC-Exo Induced N2 Polarization of Neutrophils: Implications for Angiogenesis and Tissue Restoration in Wound Healing
Jiaman Yang, Yulin Xie, Zhikuan Xia, Shuaifei Ji, Xin Yang, Danxia Yue, Yuanyuan Liu, Rongya Yang & Yunlong Fan
Pages: 3555-3575
Published online: 13 Apr 2024
AbstractforHucMSC-Exo Induced N2 Polarization of Neutrophils: Implications for Angiogenesis and Tissue Restoration in Wound Healing | Full Text | References | PDF (18.1 MB) | EPUB
  • 112 Views
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Article
Development of Ac2-26 Mesoporous Microparticle System as a Potential Therapeutic Agent for Inflammatory Bowel Diseases
Milena Fronza Broering, Pedro Leonidas Oseliero Filho, Pâmela Pacassa Borges, Luis Carlos Cides da Silva, Marcos Camargo Knirsch, Luana Filippi Xavier, Pablo Scharf, Silvana Sandri, Marco Antonio Stephano, Fernando Anselmo de Oliveira, Ibrahim M Sayed, Lionel Fernel Gamarra, Soumita Das, Márcia CA Fantini & Sandra HP Farsky
Pages: 3537-3554
Published online: 11 Apr 2024
AbstractforDevelopment of Ac2-26 Mesoporous Microparticle System as a Potential Therapeutic Agent for Inflammatory Bowel Diseases | Full Text | References | PDF (10.8 MB) | EPUB
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Article
Microfluidic Fabricated Liposomes for Nutlin-3a Ocular Delivery as Potential Candidate for Proliferative Vitreoretinal Diseases Treatment
Elisabetta Esposito, Elena Pozza, Catia Contado, Walter Pula, Olga Bortolini, Daniele Ragno, Sofia Toldo, Fabio Casciano, Agnese Bondi, Enrico Zauli, Paola Secchiero, Giorgio Zauli & Elisabetta Melloni
Pages: 3513-3536
Published online: 12 Apr 2024
AbstractforMicrofluidic Fabricated Liposomes for Nutlin-3a Ocular Delivery as Potential Candidate for Proliferative Vitreoretinal Diseases Treatment | Full Text | References | PDF (9.3 MB) | EPUB
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Article
Polarized HLA Class I Expression on Renal Tubules Hinders the Detection of Donor-Specific Urinary Extracellular Vesicles
Liang Wu, Martijn H van Heugten, Thierry PP van den Bosch, Hans Duimel, Carmen López-Iglesias, Dennis A Hesselink, Carla C Baan & Karin Boer
Pages: 3497-3511
Published online: 11 Apr 2024
AbstractforPolarized HLA Class I Expression on Renal Tubules Hinders the Detection of Donor-Specific Urinary Extracellular Vesicles | Full Text | References | PDF (10.5 MB) | EPUB
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Article
BMP7-Loaded Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Ameliorate Liver Fibrosis by Targeting Activated Hepatic Stellate Cells
Dan Zhu, Zongbin Sun, Jiayun Wei, Yulin Zhang, Wenjing An, Yan Lin & Xun Li
Pages: 3475-3495
Published online: 11 Apr 2024
AbstractforBMP7-Loaded Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Ameliorate Liver Fibrosis by Targeting Activated Hepatic Stellate Cells | Full Text | References | PDF (24.8 MB) | EPUB
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Article
Preparation and Evaluation of Chitosan Coated PLGA Nanoparticles Encapsulating Ivosidenib with Enhanced Cytotoxicity Against Human Liver Cancer Cells
Bader B Alsulays, Alhussain H Aodah, Mohammad Muqtader Ahmed & Md Khalid Anwer
Pages: 3461-3473
Published online: 09 Apr 2024
AbstractforPreparation and Evaluation of Chitosan Coated PLGA Nanoparticles Encapsulating Ivosidenib with Enhanced Cytotoxicity Against Human Liver Cancer Cells | Full Text | References | PDF (4.6 MB) | EPUB
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REVIEW

Review
The Application of Drugs and Nano-Therapies Targeting Immune Cells in Hypoxic Inflammation
Jiaxin Luo, Hanchi Wang, Jingxia Chen, Xuyan Wei, Jian Feng, Yidi Zhang & Yanmin Zhou
Pages: 3441-3459
Published online: 09 Apr 2024
AbstractforThe Application of Drugs and Nano-Therapies Targeting Immune Cells in Hypoxic Inflammation | Full Text | References | PDF (5.1 MB) | EPUB
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ORIGINAL RESEARCH

Article
Microdroplets Encapsulated with NFATc1-siRNA and Exosomes-Derived from MSCs Onto 3D Porous PLA Scaffold for Regulating Osteoclastogenesis and Promoting Osteogenesis
Peng Luo, Yi Zhang, Maodi Huang, Guochen Luo, Yaping Ma & Xin Wang
Pages: 3423-3440
Published online: 09 Apr 2024
AbstractforMicrodroplets Encapsulated with NFATc1-siRNA and Exosomes-Derived from MSCs Onto 3D Porous PLA Scaffold for Regulating Osteoclastogenesis and Promoting Osteogenesis | Full Text | References | PDF (11.1 MB) | EPUB
  • 73 Views
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Article
Self-Assembled Nanoparticles from Xie-Bai-San Decoction: Isolation, Characterization and Enhancing Oral Bioavailability
Wenlong Nie, Yun Liu, Jinshuai Lan, Ting Li, Yitian He, Zhe Li, Tong Zhang & Yue Ding
Pages: 3405-3421
Published online: 08 Apr 2024
AbstractforSelf-Assembled Nanoparticles from Xie-Bai-San Decoction: Isolation, Characterization and Enhancing Oral Bioavailability | Full Text | References | PDF (11.6 MB) | EPUB
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REVIEW

Review
Advancements in Stimulus-Responsive Co-Delivery Nanocarriers for Enhanced Cancer Immunotherapy
Meng-Ru Zhang, Lin-Lin Fang, Yang Guo, Qin Wang, You-Jie Li, Hong-Fang Sun, Shu-Yang Xie & Yan Liang
Pages: 3387-3404
Published online: 08 Apr 2024
AbstractforAdvancements in Stimulus-Responsive Co-Delivery Nanocarriers for Enhanced Cancer Immunotherapy | Full Text | References | PDF (3.6 MB) | EPUB
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ORIGINAL RESEARCH

Article
Folic Acid Functionalized AQ4N/Gd@PDA Nanoplatform with Real-Time Monitoring of Hypoxia Relief and Enhanced Synergistic Chemo/Photothermal Therapy in Glioma
Longjiang Zhou, Haitao Xiang, Susu Liu, Honglin Chen, Yuanwei Yang, Jianyong Zhang & Wei Cai
Pages: 3367-3386
Published online: 08 Apr 2024
AbstractforFolic Acid Functionalized AQ4N/Gd@PDA Nanoplatform with Real-Time Monitoring of Hypoxia Relief and Enhanced Synergistic Chemo/Photothermal Therapy in Glioma | Full Text | References | PDF (16.9 MB) | EPUB
  • 95 Views
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REVIEW

Review
The Application of Nanoparticles Targeting Cancer-Associated Fibroblasts
Qiu Huang, Yue Ge, Yu He, Jian Wu, Yonghua Tong, Haojie Shang, Xiao Liu, Xiaozhuo Ba, Ding Xia, Ejun Peng, Zhiqiang Chen & Kun Tang
Pages: 3333-3365
Published online: 08 Apr 2024
AbstractforThe Application of Nanoparticles Targeting Cancer-Associated Fibroblasts | Full Text | References | PDF (20.4 MB) | EPUB
  • 129 Views
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ORIGINAL RESEARCH

Article
Carbon Dots Derived from Curcumae Radix and Their Heartprotective Effect
Liyang Dong, Yafang Zhao, Juan Luo, Xiaopeng Li, Shuxian Wang, Menghan Li, Peng Zou, Hui Kong, Qingguo Wang, Yan Zhao & Huihua Qu
Pages: 3315-3332
Published online: 07 Apr 2024
AbstractforCarbon Dots Derived from Curcumae Radix and Their Heartprotective Effect | Full Text | References | PDF (13.2 MB) | EPUB
  • 92 Views
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Article
Engineered Exosomes with Growth Differentiation Factor-15 Overexpression Enhance Cardiac Repair After Myocardial Injury
Ailin Zou, Tingting Xiao, Boyu Chi, Yu Wang, Lipeng Mao, Dabei Cai, Qingqing Gu, Qianwen Chen, Qingjie Wang, Yuan Ji & Ling Sun
Pages: 3295-3314
Published online: 05 Apr 2024
AbstractforEngineered Exosomes with Growth Differentiation Factor-15 Overexpression Enhance Cardiac Repair After Myocardial Injury | Full Text | References | PDF (17.8 MB) | EPUB
  • 111 Views
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Article
Melt Electrowriting Combined with Fused Deposition Modeling Printing for the Fabrication of Three-Dimensional Biomimetic Scaffolds for Osteotendinous Junction Regeneration
Shengshan Ma, Suyang Zheng, Dong Li, Wenhao Hu & Liming Wang
Pages: 3275-3293
Published online: 05 Apr 2024
AbstractforMelt Electrowriting Combined with Fused Deposition Modeling Printing for the Fabrication of Three-Dimensional Biomimetic Scaffolds for Osteotendinous Junction Regeneration | Full Text | References | PDF (17.2 MB) | EPUB
  • 87 Views
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Article
Microenvironmental Enzyme-Responsive Methotrexate Modified Quercetin Micelles for the Treatment of Rheumatoid Arthritis
Xiuying Li, Xin Wang, Xiuwu Qu, Ningning Shi, Qinqing Li, Zhifang Yan, Yandong Li & Yingli Wang
Pages: 3259-3273
Published online: 05 Apr 2024
AbstractforMicroenvironmental Enzyme-Responsive Methotrexate Modified Quercetin Micelles for the Treatment of Rheumatoid Arthritis | Full Text | References | PDF (11.5 MB) | EPUB
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REVIEW

Review
Mesenchymal Stem Cell-Derived Extracellular Vesicles in Bone-Related Diseases: Intercellular Communication Messengers and Therapeutic Engineering Protagonists
Yanyi Wang, Juan Wen, Tong Lu, Wei Han, Kai Jiao & Huang Li
Pages: 3233-3257
Published online: 05 Apr 2024
AbstractforMesenchymal Stem Cell-Derived Extracellular Vesicles in Bone-Related Diseases: Intercellular Communication Messengers and Therapeutic Engineering Protagonists | Full Text | References | PDF (8.3 MB) | EPUB
  • 130 Views
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ORIGINAL RESEARCH

Article
A Multifunctional Nanozyme Integrating Antioxidant, Antimicrobial and Pro-Vascularity for Skin Wound Management
Tao Jiang, Weijian Chen, Chao Lu, Jiyong Yang, Ziquan Zeng, Wenqiang Li, Hongsheng Liu, Nana Huang, Yuhui Chen & Wengang Liu
Pages: 3217-3232
Published online: 05 Apr 2024
AbstractforA Multifunctional Nanozyme Integrating Antioxidant, Antimicrobial and Pro-Vascularity for Skin Wound Management | Full Text | References | PDF (14.1 MB) | EPUB
  • 60 Views
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REVIEW

Review
Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review
Shahbaz Ahmad, Shujaat Ahmad, Shujat Ali, Muhammad Esa, Ajmal Khan & Hai Yan
Pages: 3187-3215
Published online: 03 Apr 2024
AbstractforRecent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review | Full Text | References | PDF (8.3 MB) | EPUB
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ORIGINAL RESEARCH

Article
Analysis of Optimal Treatment Starting Time for Photothermal Therapy Through Analysis of Diffusion Behavior of Gold Nanoparticles
Donghyuk Kim & Hyunjung Kim
Pages: 3167-3186
Published online: 03 Apr 2024
AbstractforAnalysis of Optimal Treatment Starting Time for Photothermal Therapy Through Analysis of Diffusion Behavior of Gold Nanoparticles | Full Text | References | PDF (6.2 MB) | EPUB
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Article
Magnetic Graphene Oxide Nanocomposites Boosts Craniomaxillofacial Bone Regeneration by Modulating circAars/miR-128-3p/SMAD5 Signaling Axis
Yi He, Lejia Zhang, Siyuan Huang, Yuquan Tang, Yiming Li, Hongyu Li, Guanhui Chen, Xun Chen, Xiliu Zhang, Wei Zhao, Feilong Deng & Dongsheng Yu
Pages: 3143-3166
Published online: 03 Apr 2024
AbstractforMagnetic Graphene Oxide Nanocomposites Boosts Craniomaxillofacial Bone Regeneration by Modulating circAars/miR-128-3p/SMAD5 Signaling Axis | Full Text | References | PDF (20.9 MB) | EPUB
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Article
Lack of Laminar Shear Stress Facilitates the Endothelial Uptake of Very Small Superparamagnetic Iron Oxide Nanoparticles by Modulating the Endothelial Surface Layer
Shailey Gale Twamley, Niclas Gimber, Héctor Eduardo Sánchez-Ibarra, Tobias Christaller, Victoria Isakzai, Harald Kratz, Ronodeep Mitra, Lena Kampen, Anke Stach, Heike Heilmann, Berit Söhl-Kielczynski, Eno Essien Ebong, Jan Schmoranzer, Agnieszka Münster-Wandowski & Antje Ludwig
Pages: 3123-3142
Published online: 02 Apr 2024
AbstractforLack of Laminar Shear Stress Facilitates the Endothelial Uptake of Very Small Superparamagnetic Iron Oxide Nanoparticles by Modulating the Endothelial Surface Layer | Full Text | References | PDF (11.6 MB) | EPUB
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Article
Exosomes Derived from Human Palatal Mesenchymal Cells Mediate Intercellular Communication During Palatal Fusion by Promoting Oral Epithelial Cell Migration
Zhuo Huang, Yusheng Zhi, Haiyan Cao, Zhuan Bian & Miao He
Pages: 3109-3121
Published online: 29 Mar 2024
AbstractforExosomes Derived from Human Palatal Mesenchymal Cells Mediate Intercellular Communication During Palatal Fusion by Promoting Oral Epithelial Cell Migration | Full Text | References | PDF (9.8 MB) | EPUB
  • 93 Views
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Article
Lipid Nanoparticle-Based Inhibitors for SARS-CoV-2 Host Cell Infection
Vinith Yathindranath, Nura Safa, Mateusz Marek Tomczyk, Vernon Dolinsky & Donald W Miller
Pages: 3087-3108
Published online: 28 Mar 2024
AbstractforLipid Nanoparticle-Based Inhibitors for SARS-CoV-2 Host Cell Infection | Full Text | References | PDF (11.7 MB) | EPUB
  • 174 Views
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Article
Integrin αvβ3 and LHRH Receptor Double Directed Nano-Analogue Effective Against Ovarian Cancer in Mice Model
Na Qi, Xiantai Zhou, Ningzhu Ma, Jianguo Zhang, Zhenlin Wang, Xin Zhang & Aimin Li
Pages: 3071-3086
Published online: 28 Mar 2024
AbstractforIntegrin αvβ3 and LHRH Receptor Double Directed Nano-Analogue Effective Against Ovarian Cancer in Mice Model | Full Text | References | PDF (9.8 MB) | EPUB
  • 71 Views
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Article
Green Synthesis of Zinc Oxide Nanoparticles from Althaea officinalis Flower Extract Coated with Chitosan for Potential Healing Effects on Diabetic Wounds by Inhibiting TNF-α and IL-6/IL-1β Signaling Pathways
Sammar Fathy Elhabal, Nashwa Abdelaal, Saeed Abdul Kareem Saeed Al-Zuhairy, Mohamed Fathi Mohamed Elrefai, Ahmed Mohsen Elsaid Hamdan, Mohamed Mansour Khalifa, Sandra Hababeh, Mohammad Ahmad Khasawneh, Gehad M Khamis, Jakline Nelson, Passant M Mohie, Rania A Gad, Amira Rizk, Soad L Kabil, Mohamed Kandeel El-Ashery, Bhaskara R Jasti, Nahla A Elzohairy, Tayseer Elnawawy, Fatma E Hassan & Mohamed A El- Nabarawi
Pages: 3045-3070
Published online: 27 Mar 2024
AbstractforGreen Synthesis of Zinc Oxide Nanoparticles from Althaea officinalis Flower Extract Coated with Chitosan for Potential Healing Effects on Diabetic Wounds by Inhibiting TNF-α and IL-6/IL-1β Signaling Pathways | Full Text | References | PDF (9.8 MB) | EPUB
  • 365 Views
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Article
Ultrasonographic Contrast and Therapeutic Effects of Hydrogen Peroxide-Responsive Nanoparticles in a Rat Model with Sciatic Neuritis
Da-Sol Kim, Nam-Gyu Jo, Dong-Won Lee, Myoung-Hwan Ko, Jeong-Hwan Seo & Gi-Wook Kim
Pages: 3031-3044
Published online: 28 Mar 2024
AbstractforUltrasonographic Contrast and Therapeutic Effects of Hydrogen Peroxide-Responsive Nanoparticles in a Rat Model with Sciatic Neuritis | Full Text | References | PDF (6.8 MB) | EPUB
  • 81 Views
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Article
Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
Remya Valsalakumari, Abhilash D Pandya, Lina Prasmickaite, Audun Kvalvaag, Anne Grethe Myrann, Andreas KO Åslund, Marianne Steinsvik Kjos, Cristina Fontecha-Cuenca, Hajira B Haroon, Ana RS Ribeiro, Jutta Horejs-Hoeck, S Moein Moghimi, Ýrr Mørch, Tore Skotland, Kirsten Sandvig, Gunhild Mari Mælandsmo & Tore Geir Iversen
Pages: 3009-3029
Published online: 26 Mar 2024
AbstractforPreclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants | Full Text | References | PDF (8.9 MB) | EPUB
  • 101 Views
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Article
AMP-Coated TiO2 Doped ZnO Nanomaterials Enhanced Antimicrobial Activity and Efficacy in Otitis Media Treatment by Elevating Hydroxyl Radical Levels
Qianyu Bai, Yichi Zhang, Runqiu Cai, Haiyan Wu, Huiqun Fu, Xuemei Zhou, Jie Chai, Xuepeng Teng & Tianlong Liu
Pages: 2995-3007
Published online: 26 Mar 2024
AbstractforAMP-Coated TiO2 Doped ZnO Nanomaterials Enhanced Antimicrobial Activity and Efficacy in Otitis Media Treatment by Elevating Hydroxyl Radical Levels | Full Text | References | PDF (10.9 MB) | EPUB
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LETTER

Letter to the Editor
Response to Article “Kaempferia parviflora Extracellular Vesicle Loaded with Clarithromycin for the Treatment of Helicobacter pylori Infection” [Letter]
Putu Yuliandari, Masri Sembiring Maha & Novaria Sari Dewi Panjaitan
Pages: 2993-2994
Published online: 23 Mar 2024
CitationforResponse to Article “Kaempferia parviflora Extracellular Vesicle Loaded with Clarithromycin for the Treatment of Helicobacter pylori Infection” [Letter] | Full Text | References | PDF (287.7 KB) | EPUB
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ORIGINAL RESEARCH

Article
Scaffold Adhering to Peptide-Based Biomimetic Extracellular Matrix Composite Nanobioglass Promotes the Proliferation and Migration of Skin Fibroblasts Through the GSK-3β/β-Catenin Signaling Axis
Kun Cao, Zehui Wang, Xiaojiao Sun, Di Yan, Yanwen Liu, Ting Ma & Xiaojuan Sun
Pages: 2957-2972
Published online: 27 Mar 2024
AbstractforScaffold Adhering to Peptide-Based Biomimetic Extracellular Matrix Composite Nanobioglass Promotes the Proliferation and Migration of Skin Fibroblasts Through the GSK-3β/β-Catenin Signaling Axis | Full Text | References | PDF (9.4 MB) | EPUB
  • 73 Views
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Article
Bacteria-Targeting Nanoparticles with ROS-Responsive Antibiotic Release to Eradicate Biofilms and Drug-Resistant Bacteria in Endophthalmitis
Jian Yu, Huan Xu, Jiaojiao Wei, Liangliang Niu, Haohao Zhu & Chunhui Jiang
Pages: 2939-2956
Published online: 20 Mar 2024
AbstractforBacteria-Targeting Nanoparticles with ROS-Responsive Antibiotic Release to Eradicate Biofilms and Drug-Resistant Bacteria in Endophthalmitis | Full Text | References | PDF (19.7 MB) | EPUB
  • 147 Views
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Article
Electrospun L-Lysine/Amorphous Calcium Phosphate Loaded Core-Sheath Nanofibers for Managing Oral Biofilm Infections and Promoting Periodontal Tissue Repairment
Yufeng Ling, Menglu Duan, Wen Lyu, Jie Yang, Yu Liu, Shuangshuang Ren & Wenlei Wu
Pages: 2917-2938
Published online: 20 Mar 2024
AbstractforElectrospun L-Lysine/Amorphous Calcium Phosphate Loaded Core-Sheath Nanofibers for Managing Oral Biofilm Infections and Promoting Periodontal Tissue Repairment | Full Text | References | PDF (14.5 MB) | EPUB
  • 119 Views
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REVIEW

Review
Revolutionizing Antiviral Therapeutics: Unveiling Innovative Approaches for Enhanced Drug Efficacy
Sandra Megantara, Agus Rusdin, Arif Budiman, Shaharum Shamsuddin, Noratiqah Mohtar & Muchtaridi Muchtaridi
Pages: 2889-2915
Published online: 20 Mar 2024
AbstractforRevolutionizing Antiviral Therapeutics: Unveiling Innovative Approaches for Enhanced Drug Efficacy | Full Text | References | PDF (7 MB) | EPUB
  • 156 Views
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ORIGINAL RESEARCH

Article
Ginsenoside Rh2-Based Multifunctional Liposomes for Advanced Breast Cancer Therapy
Chao Hong, Anni Wang, Jiaxuan Xia, Jianming Liang, Ying Zhu, Dan Wang, Huaxing Zhan, Chunbo Feng, Xinnan Jiang, Junjie Pan & Jianxin Wang
Pages: 2879-2888
Published online: 19 Mar 2024
AbstractforGinsenoside Rh2-Based Multifunctional Liposomes for Advanced Breast Cancer Therapy | Full Text | References | PDF (6.5 MB) | EPUB
  • 77 Views
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REVIEW

Review
Neutrophil Extracellular Traps in Tumors and Potential Use of Traditional Herbal Medicine Formulations for Its Regulation
Xiang Li, Lei Hu, Abid Naeem, Shanghua Xiao, Ming Yang, Hongming Shang & Jing Zhang
Pages: 2851-2877
Published online: 19 Mar 2024
AbstractforNeutrophil Extracellular Traps in Tumors and Potential Use of Traditional Herbal Medicine Formulations for Its Regulation | Full Text | References | PDF (3 MB) | EPUB
  • 226 Views
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Review
Nano-Drug Delivery Systems Targeting CAFs: A Promising Treatment for Pancreatic Cancer
Mingjie Wang, Wenxiang Xue, Hanghang Yuan, Zhicheng Wang & Lei Yu
Pages: 2823-2849
Published online: 18 Mar 2024
AbstractforNano-Drug Delivery Systems Targeting CAFs: A Promising Treatment for Pancreatic Cancer | Full Text | References | PDF (4.5 MB) | EPUB
  • 228 Views
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ORIGINAL RESEARCH

Article
Influence of Different Ratios of DSPE-PEG2k on Ester Prodrug Self-Assembly Nanoparticles for Cell Migration and Proliferation Suppression
Huiyun Zhang, Shunru Wei, Yunfei Hu, Yu Zhang, Hao Yao, Gang Qi, Michael Adu-Frimpong & Congyong Sun
Pages: 2807-2821
Published online: 18 Mar 2024
AbstractforInfluence of Different Ratios of DSPE-PEG2k on Ester Prodrug Self-Assembly Nanoparticles for Cell Migration and Proliferation Suppression | Full Text | References | PDF (10.7 MB) | EPUB
  • 84 Views
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Article
Targeted Ultrasound Nanobubbles Therapy for Prostate Cancer via Immuno-Sonodynamic Effect
Xin Huang, Yueying Chen, Fanglu Zhong, Bin Gui, Yugang Hu, Yuxin Guo, Qing Deng & Qing Zhou
Pages: 2793-2806
Published online: 18 Mar 2024
AbstractforTargeted Ultrasound Nanobubbles Therapy for Prostate Cancer via Immuno-Sonodynamic Effect | Full Text | References | PDF (14.2 MB) | EPUB
  • 138 Views
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REVIEW

Review
Emerging Strategies to Overcome Current CAR-T Therapy Dilemmas - Exosomes Derived from CAR-T Cells
Dong Hu, Ruyue Yang, Guidan Wang, Hao Li, Xulong Fan & Gaofeng Liang
Pages: 2773-2791
Published online: 18 Mar 2024
AbstractforEmerging Strategies to Overcome Current CAR-T Therapy Dilemmas - Exosomes Derived from CAR-T Cells | Full Text | References | PDF (8.7 MB) | EPUB
  • 226 Views
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IL-12-Overexpressed Nanoparticles Suppress the Proliferation of Melanoma Through Inducing ICD and Activating DC, CD8+ T, and CD4+ T Cells
Huan-Huan Shen, Jie-Fei Peng, Ran-Ran Wang, Ping-Yu Wang, Jia-Xiang Zhang, Hong-Fang Sun, Yan Liang, Yan-Mei Li, Jiang-Nan Xue, You-Jie Li, Guang-Bin Sun & Shu-Yang Xie
Pages: 2755-2772
Published online: 18 Mar 2024
AbstractforIL-12-Overexpressed Nanoparticles Suppress the Proliferation of Melanoma Through Inducing ICD and Activating DC, CD8+ T, and CD4+ T Cells | Full Text | References | PDF (15.9 MB) | EPUB
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Review
Polymeric Nanohydrogel in Topical Drug Delivery System
Nia Yuniarsih, Anis Yohana Chaerunisaa, Khaled M Elamin & Nasrul Wathoni
Pages: 2733-2754
Published online: 14 Mar 2024
AbstractforPolymeric Nanohydrogel in Topical Drug Delivery System | Full Text | References | PDF (1.9 MB) | EPUB
  • 249 Views
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Article
The Dual Angiogenesis Effects via Nrf2/HO-1 Signaling Pathway of Melatonin Nanocomposite Scaffold on Promoting Diabetic Bone Defect Repair
Tingting Chen, Zimei Wu, Qiaodan Hou, Yixin Mei, Kunkun Yang, Jing Xu & Lin Wang
Pages: 2709-2732
Published online: 15 Mar 2024
AbstractforThe Dual Angiogenesis Effects via Nrf2/HO-1 Signaling Pathway of Melatonin Nanocomposite Scaffold on Promoting Diabetic Bone Defect Repair | Full Text | References | PDF (20.3 MB) | EPUB
  • 142 Views
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Article
Utilization of Nitrogen-Doped Graphene Quantum Dots to Neutralize ROS and Modulate Intracellular Antioxidant Pathways to Improve Dry Eye Disease Therapy
Zixia Wu, Weibo Xia, Liling Ou, Ling Zheng, Bingying Hou, Tonghe Pan, Wenjie Sun, Leo H Koole, Yongqing Shao & Lei Qi
Pages: 2691-2708
Published online: 14 Mar 2024
AbstractforUtilization of Nitrogen-Doped Graphene Quantum Dots to Neutralize ROS and Modulate Intracellular Antioxidant Pathways to Improve Dry Eye Disease Therapy | Full Text | References | PDF (8.5 MB) | EPUB
  • 142 Views
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Article
Anti-Tumor Efficacy of Oleuropein-Loaded ZnO/Au Mesoporous Silica Nanoparticle in 5-FU-Resistant Colorectal Cancer Cells
Sang Mi Park, Da Yeon Kim, Kyeong Hyeon Lee, Yong-Il Shin, Sang-Cheol Han & Sang-Mo Kwon
Pages: 2675-2690
Published online: 14 Mar 2024
AbstractforAnti-Tumor Efficacy of Oleuropein-Loaded ZnO/Au Mesoporous Silica Nanoparticle in 5-FU-Resistant Colorectal Cancer Cells | Full Text | References | PDF (7.5 MB) | EPUB
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Article
Ionizable Lipid Nanoparticle-Mediated TRAIL mRNA Delivery in the Tumor Microenvironment to Inhibit Colon Cancer Progression
Walison Nunes da Silva, Pedro Augusto Carvalho Costa, Sérgio Ricardo Aluotto Scalzo Júnior, Heloísa AS Ferreira, Pedro Henrique Dias Moura Prazeres, Caroline Leonel Vasconcelos Campos, Marco Túllio Rodrigues Alves, Natália Jordana Alves da Silva, Ana Luiza de Castro Santos, Lays Cordeiro Guimarães, Maria Eduarda Chen Ferris, Ajay Thatte, Alex Hamilton, Kelly Alves Bicalho, Anderson Oliveira Lobo, Helton da Costa Santiago, Lucíola da Silva Barcelos, Maria Marta Figueiredo, Mauro Martins Teixeira, Vivian Vasconcelos Costa, Michael J Mitchell, Frédéric Frézard & Pedro Pires Goulart Guimaraes
Pages: 2655-2673
Published online: 14 Mar 2024
AbstractforIonizable Lipid Nanoparticle-Mediated TRAIL mRNA Delivery in the Tumor Microenvironment to Inhibit Colon Cancer Progression | Full Text | References | PDF (11.3 MB) | EPUB
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Article
Lipid-Based Self-Microemulsion of Niclosamide Achieved Enhanced Oral Delivery and Anti-Tumor Efficacy in Orthotopic Patient-Derived Xenograft of Hepatocellular Carcinoma in Mice
Yi Liu, David Quintanar Guerrero, David Lechuga-Ballesteros, Mingdian Tan, Faiz Ahmad, Bilal Aleiwi, Edmund Lee Ellsworth, Bin Chen, Mei-Sze Chua & Samuel So
Pages: 2639-2653
Published online: 15 Mar 2024
AbstractforLipid-Based Self-Microemulsion of Niclosamide Achieved Enhanced Oral Delivery and Anti-Tumor Efficacy in Orthotopic Patient-Derived Xenograft of Hepatocellular Carcinoma in Mice | Full Text | References | PDF (7.7 MB) | EPUB
  • 150 Views
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Article
Topical Delivery of microRNA-125b by Framework Nucleic Acids for Psoriasis Treatment
Yunfeng Han, Long Xi, Fang Leng, Chenjie Xu & Ying Zheng
Pages: 2625-2638
Published online: 14 Mar 2024
AbstractforTopical Delivery of microRNA-125b by Framework Nucleic Acids for Psoriasis Treatment | Full Text | References | PDF (9.4 MB) | EPUB
  • 166 Views
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Article
High-Performance Photodynamic Therapy of Tongue Squamous Cell Carcinoma with Multifunctional Nano-Verteporfin
Lina Yu, Zidan Xu, Guanxiong Zhu, Liting Zeng, Zeyu Zhang, Yang Yu, Siran Wang, Xin Zhang, Na Zhou & Lu Liang
Pages: 2611-2623
Published online: 13 Mar 2024
AbstractforHigh-Performance Photodynamic Therapy of Tongue Squamous Cell Carcinoma with Multifunctional Nano-Verteporfin | Full Text | References | PDF (9.9 MB) | EPUB
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Review
Emerging Drug Delivery Vectors: Engineering of Plant-Derived Nanovesicles and Their Applications in Biomedicine
Lu-Yao Yang, Chao-Qing Li, Yu-Lin Zhang, Meng-Wen Ma, Wan Cheng & Guo-Jun Zhang
Pages: 2591-2610
Published online: 13 Mar 2024
AbstractforEmerging Drug Delivery Vectors: Engineering of Plant-Derived Nanovesicles and Their Applications in Biomedicine | Full Text | References | PDF (9.8 MB) | EPUB
  • 239 Views
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Article
Oriented Graphene Oxide Scaffold Promotes Nerve Regeneration in vitro and in vivo
Xu Zhou, Aolin Tang, Chengjie Xiong, Guoquan Zhang, Liangliang Huang & Feng Xu
Pages: 2573-2589
Published online: 13 Mar 2024
AbstractforOriented Graphene Oxide Scaffold Promotes Nerve Regeneration in vitro and in vivo | Full Text | References | PDF (13.6 MB) | EPUB
  • 115 Views
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Article
Targeted Delivery of Mesenchymal Stem Cell-Derived Bioinspired Exosome-Mimetic Nanovesicles with Platelet Membrane Fusion for Atherosclerotic Treatment
Yu Jiang, Miao Yu, Zhi-Feng Song, Zhi-Yao Wei, Ji Huang & Hai-Yan Qian
Pages: 2553-2571
Published online: 14 Mar 2024
AbstractforTargeted Delivery of Mesenchymal Stem Cell-Derived Bioinspired Exosome-Mimetic Nanovesicles with Platelet Membrane Fusion for Atherosclerotic Treatment | Full Text | References | PDF (14.1 MB) | EPUB
  • 228 Views
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Review
Nanoparticle-Based Combinational Strategies for Overcoming the Blood-Brain Barrier and Blood-Tumor Barrier
Su Hyun Lim, Gi Taek Yee & Dongwoo Khang
Pages: 2529-2552
Published online: 13 Mar 2024
AbstractforNanoparticle-Based Combinational Strategies for Overcoming the Blood-Brain Barrier and Blood-Tumor Barrier | Full Text | References | PDF (7.9 MB) | EPUB
  • 493 Views
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Review
Exploiting Nanotechnology for Drug Delivery: Advancing the Anti-Cancer Effects of Autophagy-Modulating Compounds in Traditional Chinese Medicine
Zixian Liu, Tianming Lu, Ruoning Qian, Zian Wang, Ruogu Qi & Zhengguang Zhang
Pages: 2507-2528
Published online: 13 Mar 2024
AbstractforExploiting Nanotechnology for Drug Delivery: Advancing the Anti-Cancer Effects of Autophagy-Modulating Compounds in Traditional Chinese Medicine | Full Text | References | PDF (5.9 MB) | EPUB
  • 179 Views
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Article
Design and Self-Assembly of Peptide-Copolymer Conjugates into Nanoparticle Hydrogel for Wound Healing in Diabetes
Yiling Lin, Yingneng Zhang, Xia Cai, Huashen He, Chuangzan Yang, Junfeng Ban & Bohong Guo
Pages: 2487-2506
Published online: 08 Mar 2024
AbstractforDesign and Self-Assembly of Peptide-Copolymer Conjugates into Nanoparticle Hydrogel for Wound Healing in Diabetes | Full Text | References | PDF (16.6 MB) | EPUB
  • 261 Views
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Article
Highly Ordered Nanotube-Like Microstructure on Titanium Dental Implant Surface Fabricated via Anodization Enhanced Cell Adhesion and Migration of Human Gingival Fibroblasts
Zhaoming Deng, Lerong Yu, Yishen Kuang, Ziyao Zhou & Xiangwei Li
Pages: 2469-2485
Published online: 08 Mar 2024
AbstractforHighly Ordered Nanotube-Like Microstructure on Titanium Dental Implant Surface Fabricated via Anodization Enhanced Cell Adhesion and Migration of Human Gingival Fibroblasts | Full Text | References | PDF (14.3 MB) | EPUB
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Review
How Precise are Nanomedicines in Overcoming the Blood–Brain Barrier? A Comprehensive Review of the Literature
Priyadarshini Mohapatra, Mohanraj Gopikrishnan, George Priya Doss C & Natarajan Chandrasekaran
Pages: 2441-2467
Published online: 11 Mar 2024
AbstractforHow Precise are Nanomedicines in Overcoming the Blood–Brain Barrier? A Comprehensive Review of the Literature | Full Text | References | PDF (6.1 MB) | EPUB
  • 301 Views
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Article
A SARS-CoV-2 Nanobody Displayed on the Surface of Human Ferritin with High Neutralization Activity
Wenrong Zhang, Haining Wang, Tong Wu, Xintao Gao, Yuting Shang, Zhifang Zhang, Xingjian Liu & Yinü Li
Pages: 2429-2440
Published online: 08 Mar 2024
AbstractforA SARS-CoV-2 Nanobody Displayed on the Surface of Human Ferritin with High Neutralization Activity | Full Text | References | PDF (5.9 MB) | EPUB
  • 112 Views
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Article
Dual-Stimuli-Responsive Gut Microbiota-Targeting Nitidine Chloride-CS/PT-NPs Improved Metabolic Status in NAFLD
Jianmei Lu, Yongzhu Zeng, Huashuai Zhong, Wei Guo, Yuyan Zhang, Wanting Mai, Yucui Qin, Xiaodan Su, Bo Zhang, Weisen Wu, Yu Zhu, Qiujie Huang & Yong Ye
Pages: 2409-2428
Published online: 07 Mar 2024
AbstractforDual-Stimuli-Responsive Gut Microbiota-Targeting Nitidine Chloride-CS/PT-NPs Improved Metabolic Status in NAFLD | Full Text | References | PDF (15.6 MB) | EPUB
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Article
Pioneering Astaxanthin-Tumor Cell Membrane Nanoparticles for Innovative Targeted Drug Delivery on Melanoma
Jui-Jen Chang, Yi-Chen Wang, Shu-Hui Yang, Ju-Yu Wu, Ming-Wei Chang & Hui-Min David Wang
Pages: 2395-2407
Published online: 07 Mar 2024
AbstractforPioneering Astaxanthin-Tumor Cell Membrane Nanoparticles for Innovative Targeted Drug Delivery on Melanoma | Full Text | References | PDF (5.8 MB) | EPUB
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Review
Engineered Extracellular Vesicles in Chronic Kidney Diseases: A Comprehensive Review
Kaming Xue & Bobin Mi
Pages: 2377-2393
Published online: 07 Mar 2024
AbstractforEngineered Extracellular Vesicles in Chronic Kidney Diseases: A Comprehensive Review | Full Text | References | PDF (7.4 MB) | EPUB
  • 157 Views
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Article
Potential Exploration of Biocompatible Carbon-Coated MoSe2 Nanoparticles for Exploration of the Photothermal Potential in the Treatment of Human Choriocarcinoma
Hui Yu, Xinyi He, Jinmeng Yao, Xiaoya Gu, Lin Zhou, Li Gao & Jia Wang
Pages: 2359-2375
Published online: 06 Mar 2024
AbstractforPotential Exploration of Biocompatible Carbon-Coated MoSe2 Nanoparticles for Exploration of the Photothermal Potential in the Treatment of Human Choriocarcinoma | Full Text | References | PDF (13.1 MB) | EPUB
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Article
Reduced Graphene Oxide Fibers Combined with Electrical Stimulation Promote Peripheral Nerve Regeneration
Yuanyuan Zhao, Yang Liu, Cheng Lu, Daokuan Sun, Shiqi Kang, Xin Wang & Laijin Lu
Pages: 2341-2357
Published online: 07 Mar 2024
AbstractforReduced Graphene Oxide Fibers Combined with Electrical Stimulation Promote Peripheral Nerve Regeneration | Full Text | References | PDF (17.8 MB) | EPUB
  • 139 Views
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Review
Polymersomes for Therapeutic Protein and Peptide Delivery: Towards Better Loading Properties
Chengxu Hua & Liyan Qiu
Pages: 2317-2340
Published online: 06 Mar 2024
AbstractforPolymersomes for Therapeutic Protein and Peptide Delivery: Towards Better Loading Properties | Full Text | References | PDF (14 MB) | EPUB
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Article
Glutathione Depletion-Induced ROS/NO Generation for Cascade Breast Cancer Therapy and Enhanced Anti-Tumor Immune Response
Jing Wang, Yanxiang Sang, Weijian Chen, Liang Cheng, Wenxiang Du, Hongjie Zhang, Benyan Zheng, Lei Song, Yuan Hu & Xiaopeng Ma
Pages: 2301-2315
Published online: 06 Mar 2024
AbstractforGlutathione Depletion-Induced ROS/NO Generation for Cascade Breast Cancer Therapy and Enhanced Anti-Tumor Immune Response | Full Text | References | PDF (10.7 MB) | EPUB
  • 121 Views
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Article
Recombinant Human Heavy Chain Ferritin Nanoparticles Serve as ROS Scavengers for the Treatment of Ischemic Stroke
Mi Qi, Yajuan Cheng, Ke Liu, Jingxing Cai, Tianyu Liu, Xiaoying Wu, Huili Tang, He Huang, Qinbiao Chen & Xiaoguang Zhou
Pages: 2285-2299
Published online: 07 Mar 2024
AbstractforRecombinant Human Heavy Chain Ferritin Nanoparticles Serve as ROS Scavengers for the Treatment of Ischemic Stroke | Full Text | References | PDF (14.6 MB) | EPUB
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Article
Chitosan-Rapamycin Carbon Dots Alleviate Glaucomatous Retinal Injury by Inducing Autophagy to Promote M2 Microglial Polarization
Qi Wang, Jiaxin Dong, Mengxian Du, Xinna Liu, Shiqi Zhang, Di Zhang, Wanyun Qin, Xikun Xu, Xianghui Li, Ruidong Su, Leyi Qiu, Baoqiang Li & Huiping Yuan
Pages: 2265-2284
Published online: 07 Mar 2024
AbstractforChitosan-Rapamycin Carbon Dots Alleviate Glaucomatous Retinal Injury by Inducing Autophagy to Promote M2 Microglial Polarization | Full Text | References | PDF (12.9 MB) | EPUB
  • 124 Views
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Review
Extracellular Vesicles: A New Star for Gene Drug Delivery
Man Sun, Huan Zhang, Jiayi Liu, Jiayi Chen, Yaxin Cui, Simiao Wang, Xiangyu Zhang & Zhaogang Yang
Pages: 2241-2264
Published online: 05 Mar 2024
AbstractforExtracellular Vesicles: A New Star for Gene Drug Delivery | Full Text | References | PDF (9.5 MB) | EPUB
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Article
Drug-Loaded Tumor-Derived Microparticles Elicit CD8+ T Cell-Mediated Anti-Tumor Response in Hepatocellular Carcinoma
Yulin Chen, Yi Zhang, Jianjun Wang, Xiong Cai, Junzhang Chen, Xiaobo Min, Yunjie Xu, Qi Qin & Chidan Wan
Pages: 2227-2239
Published online: 05 Mar 2024
AbstractforDrug-Loaded Tumor-Derived Microparticles Elicit CD8+ T Cell-Mediated Anti-Tumor Response in Hepatocellular Carcinoma | Full Text | References | PDF (8.9 MB) | EPUB
  • 76 Views
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Review
Characterization of Drug with Good Glass-Forming Ability Loaded Mesoporous Silica Nanoparticles and Its Impact Toward in vitro and in vivo Studies
Arif Budiman, Gracia Anastasya, Annisa Luthfiyah Handini, Ira Novianty Lestari, Laila Subra & Diah Lia Aulifa
Pages: 2199-2225
Published online: 05 Mar 2024
AbstractforCharacterization of Drug with Good Glass-Forming Ability Loaded Mesoporous Silica Nanoparticles and Its Impact Toward in vitro and in vivo Studies | Full Text | References | PDF (6 MB) | EPUB
  • 197 Views
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Article
Development of an Intelligent Reactive Oxygen Species-Responsive Dual-Drug Delivery Nanoplatform for Enhanced Precise Therapy of Acute Lung Injury
Dunling Xia, Zongqing Lu, Shuai Li, Pu Fang, Chun Yang, Xiaoyan He, Qinghai You & Gengyun Sun
Pages: 2179-2197
Published online: 05 Mar 2024
AbstractforDevelopment of an Intelligent Reactive Oxygen Species-Responsive Dual-Drug Delivery Nanoplatform for Enhanced Precise Therapy of Acute Lung Injury | Full Text | References | PDF (13.5 MB) | EPUB
  • 151 Views
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Article
Co-Delivery of Aceclofenac and Methotrexate Nanoparticles Presents an Effective Treatment for Rheumatoid Arthritis
Sushmita Negi, Nikunj Tandel, Neeraj K Garg, Prakriti Sharma, Rajinder Kumar, Praveen Sharma, Reetesh Kumar, Sheetal Saini, Aman Sharma & Rajeev K Tyagi
Pages: 2149-2177
Published online: 04 Mar 2024
AbstractforCo-Delivery of Aceclofenac and Methotrexate Nanoparticles Presents an Effective Treatment for Rheumatoid Arthritis | Full Text | References | PDF (16.6 MB) | EPUB
  • 267 Views
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Article
Bare-Metal Stent Tracking with Magnetic Particle Imaging
Franz Wegner, Thomas Friedrich, Maximilian Wattenberg, Justin Ackers, Malte Maria Sieren, Roman Kloeckner, Joerg Barkhausen, Thorsten M Buzug, Matthias Graeser & Anselm von Gladiss
Pages: 2137-2148
Published online: 04 Mar 2024
AbstractforBare-Metal Stent Tracking with Magnetic Particle Imaging | Full Text | References | PDF (4.8 MB) | EPUB
  • 96 Views
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Article
Shear Bond Strength to Enamel, Mechanical Properties and Cellular Studies of Fiber-Reinforced Composites Modified by Depositing SiO2 Nanofilms on Quartz Fibers via Atomic Layer Deposition
Fei Shu, Hong Chen, Zhihao Zhang, Zhiyue Dun, Weijin Lv, Wangxinyue Sun & Mei Liu
Pages: 2113-2136
Published online: 05 Mar 2024
AbstractforShear Bond Strength to Enamel, Mechanical Properties and Cellular Studies of Fiber-Reinforced Composites Modified by Depositing SiO2 Nanofilms on Quartz Fibers via Atomic Layer Deposition | Full Text | References | PDF (17.4 MB) | EPUB
  • 103 Views
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Review
Advances in Ferroptosis-Inducing Agents by Targeted Delivery System in Cancer Therapy
Debiao Xiang, Lili Zhou, Rui Yang, Fang Yuan, Yilin Xu, Yuan Yang, Yong Qiao & Xin Li
Pages: 2091-2112
Published online: 04 Mar 2024
AbstractforAdvances in Ferroptosis-Inducing Agents by Targeted Delivery System in Cancer Therapy | Full Text | References | PDF (4.3 MB) | EPUB
  • 183 Views
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Article
MSC-Derived Exosomes Mitigate Myocardial Ischemia/Reperfusion Injury by Reducing Neutrophil Infiltration and the Formation of Neutrophil Extracellular Traps
Yuting Feng, Xue Bao, Jinxuan Zhao, Lina Kang, Xuan Sun & Biao Xu
Pages: 2071-2090
Published online: 04 Mar 2024
AbstractforMSC-Derived Exosomes Mitigate Myocardial Ischemia/Reperfusion Injury by Reducing Neutrophil Infiltration and the Formation of Neutrophil Extracellular Traps | Full Text | References | PDF (13.8 MB) | EPUB
  • 124 Views
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Article
Dissolving Microneedle-Based Cascade-Activation Nanoplatform for Enhanced Photodynamic Therapy of Skin Cancer
Jinyuan Ma, Zongguang Tai, Ying Li, Yang Li, Jiandong Wang, Tao Zhou, Min Shen, Rujuan Xin, Cuie Shen, Quangang Zhu & Zhongjian Chen
Pages: 2057-2070
Published online: 04 Mar 2024
AbstractforDissolving Microneedle-Based Cascade-Activation Nanoplatform for Enhanced Photodynamic Therapy of Skin Cancer | Full Text | References | PDF (14.6 MB) | EPUB
  • 117 Views
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Article
Blood-Nanoparticle Interactions Create a Brain Delivery Superhighway for Doxorubicin
Zhuoxuan Li, Tatyana Kovshova, Julia Malinovskaya, Julian Knoll, Saeed Shanehsazzadeh, Nadezhda Osipova, Anastasia Chernysheva, Pavel Melnikov, Svetlana Gelperina & Matthias G Wacker
Pages: 2039-2056
Published online: 04 Mar 2024
AbstractforBlood-Nanoparticle Interactions Create a Brain Delivery Superhighway for Doxorubicin | Full Text | References | PDF (7.6 MB) | EPUB
  • 176 Views
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Article
Zinc Oxide Nanoparticles Exacerbate Epileptic Seizures by Modulating the TLR4-Autophagy Axis
Pingyang Ke, Jing Liu, Chengzhi Chen, Sen Luo, Huiwen Gu, Juan Gu, Yan Liu, Yuanlin Ma, Yuan Meng, Liqin Hu, Xin Tian & Fei Xiao
Pages: 2025-2038
Published online: 01 Mar 2024
AbstractforZinc Oxide Nanoparticles Exacerbate Epileptic Seizures by Modulating the TLR4-Autophagy Axis | Full Text | References | PDF (13.4 MB) | EPUB
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Article
Nicorandil-Pretreated Mesenchymal Stem Cell-Derived Exosomes Facilitate Cardiac Repair After Myocardial Infarction via Promoting Macrophage M2 Polarization by Targeting miR-125a-5p/TRAF6/IRF5 Signaling Pathway
Zhao-Ting Gong, Yu-Yan Xiong, Yu Ning, Rui-Jie Tang, Jun-Yan Xu, Wen-Yang Jiang, Xiao-Song Li, Li-Li Zhang, Cheng Chen, Qi Pan, Meng-Jin Hu, Jing Xu & Yue-Jin Yang
Pages: 2005-2024
Published online: 28 Feb 2024
AbstractforNicorandil-Pretreated Mesenchymal Stem Cell-Derived Exosomes Facilitate Cardiac Repair After Myocardial Infarction via Promoting Macrophage M2 Polarization by Targeting miR-125a-5p/TRAF6/IRF5 Signaling Pathway | Full Text | References | PDF (17 MB) | EPUB
  • 170 Views
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Article
Anti-Cancer Potency of Copper-Doped Carbon Quantum Dots Against Breast Cancer Progression
Mengqi Wang, Shuting Lan, Wenqi Zhang, Qin Jin, Hua Du, Xiaomei Sun, Lijun He, Xiangyun Meng, Liya Su & Gang Liu
Pages: 1985-2004
Published online: 26 Feb 2024
AbstractforAnti-Cancer Potency of Copper-Doped Carbon Quantum Dots Against Breast Cancer Progression | Full Text | References | PDF (12.7 MB) | EPUB
  • 175 Views
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Article
Kaempferia parviflora Extracellular Vesicle Loaded with Clarithromycin for the Treatment of Helicobacter pylori Infection
Variya Nemidkanam, Wijit Banlunara & Nuntaree Chaichanawongsaroj
Pages: 1967-1983
Published online: 26 Feb 2024
AbstractforKaempferia parviflora Extracellular Vesicle Loaded with Clarithromycin for the Treatment of Helicobacter pylori Infection | Full Text | References | PDF (5.8 MB) | EPUB
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Article
Development of Curcumin and Turmerone Loaded Solid Lipid Nanoparticle for Topical Delivery: Optimization, Characterization and Skin Irritation Evaluation with 3D Tissue Model
Beyza Sümeyye Aydin, Ali Asram Sagiroglu, Dilek Ozturk Civelek, Mustafa Gokce & Fatemeh Bahadori
Pages: 1951-1966
Published online: 25 Feb 2024
AbstractforDevelopment of Curcumin and Turmerone Loaded Solid Lipid Nanoparticle for Topical Delivery: Optimization, Characterization and Skin Irritation Evaluation with 3D Tissue Model | Full Text | References | PDF (2.7 MB) | EPUB
  • 240 Views
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Review
Exosomes as Powerful Biomarkers in Cancer: Recent Advances in Isolation and Detection Techniques
Qiongdan Zhang, Huizhen Wang, Qingyi Liu, Ni Zeng, Gang Fu, Yixing Qiu, Yupei Yang, Hanwen Yuan, Wei Wang & Bin Li
Pages: 1923-1949
Published online: 25 Feb 2024
AbstractforExosomes as Powerful Biomarkers in Cancer: Recent Advances in Isolation and Detection Techniques | Full Text | References | PDF (11.7 MB) | EPUB
  • 287 Views
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Article
Development of Small HN Linked Radionuclide Iodine-125 for Nanocarrier Image Tracing in Mouse Model
Ronglin Ma, Chunya Ji, Mengdan Shen, Shujuan Xu, Guojia Fan, Chengcheng Wu, Qiang Yu & Linliang Yin
Pages: 1909-1922
Published online: 23 Feb 2024
AbstractforDevelopment of Small HN Linked Radionuclide Iodine-125 for Nanocarrier Image Tracing in Mouse Model | Full Text | References | PDF (5.9 MB) | EPUB
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Article
Topical Ophthalmic Liposomes Dual-Modified with Penetratin and Hyaluronic Acid for the Noninvasive Treatment of Neovascular Age-Related Macular Degeneration
Chen Sun, Shuyue Zhang, Nan Xu, Kun Liu, Fang Wei, Xiaoqian Zhang, Jigang Zhang, Shen Gao, Yuan Yu & Xueying Ding
Pages: 1887-1908
Published online: 22 Feb 2024
AbstractforTopical Ophthalmic Liposomes Dual-Modified with Penetratin and Hyaluronic Acid for the Noninvasive Treatment of Neovascular Age-Related Macular Degeneration | Full Text | References | PDF (14.3 MB) | EPUB
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Review
Nanoparticles for the Treatment of Bone Metastasis in Breast Cancer: Recent Advances and Challenges
Xianzhe Yu & Lingling Zhu
Pages: 1867-1886
Published online: 23 Feb 2024
AbstractforNanoparticles for the Treatment of Bone Metastasis in Breast Cancer: Recent Advances and Challenges | Full Text | References | PDF (4.4 MB) | EPUB
  • 248 Views
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Article
LGR5 as a Therapeutic Target of Antibody-Functionalized Biomimetic Magnetoliposomes for Colon Cancer Therapy
Ana Cepero, Mónica Jiménez-Carretero, Ylenia Jabalera, Lidia Gago, Cristina Luque, Laura Cabeza, Consolación Melguizo, Concepcion Jimenez-Lopez & José Prados
Pages: 1843-1865
Published online: 23 Feb 2024
AbstractforLGR5 as a Therapeutic Target of Antibody-Functionalized Biomimetic Magnetoliposomes for Colon Cancer Therapy | Full Text | References | PDF (16.7 MB) | EPUB
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Article
Localized Administration of Bcar3 siRNA via Nano-Self-Assembly to Treat Idiopathic Pulmonary Fibrosis by Disrupting Macrophage-Fibroblast Crosstalk
Chenxi Zeng, Qi Wang, Xuhan Liu, Kai Wang, Congjian Wang, Xuetao Ju, Tianlai Wang, Qing Zhou, Xiangning Fu, Jun Yu & Yi Wang
Pages: 1827-1842
Published online: 23 Feb 2024
AbstractforLocalized Administration of Bcar3 siRNA via Nano-Self-Assembly to Treat Idiopathic Pulmonary Fibrosis by Disrupting Macrophage-Fibroblast Crosstalk | Full Text | References | PDF (11.1 MB) | EPUB
  • 113 Views
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Article
Combined Photosensitive Gene Therapy Effective Against Triple-Negative Breast Cancer in Mice Model
Yixue Hu, Dongna Wang, Tianyu Zhang, Meng Lei, Yingnan Luo, Zhimeng Chen, Yuting Li, Dandan Duan, Liefeng Zhang & Yongqiang Zhu
Pages: 1809-1825
Published online: 23 Feb 2024
AbstractforCombined Photosensitive Gene Therapy Effective Against Triple-Negative Breast Cancer in Mice Model | Full Text | References | PDF (13.2 MB) | EPUB
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REVIEW

Review
Recent Advances in Intranasal Administration for Brain-Targeting Delivery: A Comprehensive Review of Lipid-Based Nanoparticles and Stimuli-Responsive Gel Formulations
Jain Koo, Chaemin Lim & Kyung Taek Oh
Pages: 1767-1807
Published online: 27 Feb 2024
AbstractforRecent Advances in Intranasal Administration for Brain-Targeting Delivery: A Comprehensive Review of Lipid-Based Nanoparticles and Stimuli-Responsive Gel Formulations | Full Text | References | PDF (12 MB) | EPUB
  • 349 Views
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Article
Efficient Sequential Co-Delivery Nanosystem for Inhibition of Tumor and Tumor-Associated Fibroblast-Induced Resistance and Metastasis
Chunhong Li, Zhen Wang, Yifeng Zhang, Yuqing Zhu, Maochang Xu, Hui Lei & Dan Zhang
Pages: 1749-1766
Published online: 22 Feb 2024
AbstractforEfficient Sequential Co-Delivery Nanosystem for Inhibition of Tumor and Tumor-Associated Fibroblast-Induced Resistance and Metastasis | Full Text | References | PDF (17 MB) | EPUB
  • 113 Views
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Review
Natural Products-Based Inhaled Formulations for Treating Pulmonary Diseases
Jiangyan Yong, Hongli Shu, Xiao Zhang, Kun Yang, Guining Luo, Lu Yu, Jiaqi Li & Hong Huang
Pages: 1723-1748
Published online: 23 Feb 2024
AbstractforNatural Products-Based Inhaled Formulations for Treating Pulmonary Diseases | Full Text | References | PDF (2.2 MB) | EPUB
  • 342 Views
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ORIGINAL RESEARCH

Article
Characterization of Nanohybridosomes from Lipids and Spruce Homogenate Containing Extracellular Vesicles
Vesna Spasovski, Anna Romolo, Urška Zagorc, Vesna Arrigler, Matic Kisovec, Apolonija Bedina Zavec, Matevž Arko, Adrienn Molnár, Gitta Schlosser, Aleš Iglič, Ksenija Kogej & Veronika Kralj-Iglič
Pages: 1709-1721
Published online: 21 Feb 2024
AbstractforCharacterization of Nanohybridosomes from Lipids and Spruce Homogenate Containing Extracellular Vesicles | Full Text | References | PDF (5.2 MB) | EPUB
  • 136 Views
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Article
Platelet Membrane Biomimetic Manganese Carbonate Nanoparticles Promote Breast Cancer Stem Cell Clearance for Sensitized Radiotherapy
Yi Jiang, Xiaoming Liao, Wei Tang, Chunyu Huang, You Pan & Shipeng Ning
Pages: 1699-1707
Published online: 20 Feb 2024
AbstractforPlatelet Membrane Biomimetic Manganese Carbonate Nanoparticles Promote Breast Cancer Stem Cell Clearance for Sensitized Radiotherapy | Full Text | References | PDF (9.4 MB) | EPUB
  • 130 Views
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Article
Hydrophilic/Hydrophobic Janus Nanofibers Containing Compound K for Cartilage Regeneration
Hyun Ho Shin, Junyoung Park, Yeo-Jin Kim, Donghyeon Kim, Eun-Jung Jin & Ji Hyun Ryu
Pages: 1683-1697
Published online: 29 Feb 2024
AbstractforHydrophilic/Hydrophobic Janus Nanofibers Containing Compound K for Cartilage Regeneration | Full Text | References | PDF (15 MB) | EPUB
  • 127 Views
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Article
Application of Three-Dimension Printing Nano-Carbonated-Hydroxylapatite to the Repair of Defects in Rabbit Bone
Shujie Wang, Chunyan Shao, Xingkai Zhao, Yizhe Guo, Houhui Song, Lida Shen, Zhenlei Zhou & Zhen Li
Pages: 1667-1681
Published online: 20 Feb 2024
AbstractforApplication of Three-Dimension Printing Nano-Carbonated-Hydroxylapatite to the Repair of Defects in Rabbit Bone | Full Text | References | PDF (12.1 MB) | EPUB
  • 108 Views
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Article
Accumulation of Iron Oxide-Based Contrast Agents in Rabbit Atherosclerotic Plaques in Relation to Plaque Age and Vulnerability Features
Alexander Sekita, Harald Unterweger, Sonja Berg, Sabine Ohlmeyer, Tobias Bäuerle, Kang H Zheng, Bram F Coolen, Aart J Nederveen, Claudia Cabella, Silvia Rossi, Erik SG Stroes, Christoph Alexiou, Stefan Lyer & Iwona Cicha
Pages: 1645-1666
Published online: 20 Feb 2024
AbstractforAccumulation of Iron Oxide-Based Contrast Agents in Rabbit Atherosclerotic Plaques in Relation to Plaque Age and Vulnerability Features | Full Text | References | PDF (11.3 MB) | EPUB
  • 146 Views
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Article
Anticipation and Verification of Dendrobium-Derived Nanovesicles for Skin Wound Healing Targets, Predicated Upon Immune Infiltration and Senescence
Jin Tu, Feng Jiang, Jieni Fang, Luhua Xu, Zhicong Zeng, Xuanyue Zhang, Li Ba, Hanjiao Liu & Fengxia Lin
Pages: 1629-1644
Published online: 19 Feb 2024
AbstractforAnticipation and Verification of Dendrobium-Derived Nanovesicles for Skin Wound Healing Targets, Predicated Upon Immune Infiltration and Senescence | Full Text | References | PDF (11.8 MB) | EPUB
  • 155 Views
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REVIEW

Review
Macrophage-Derived Exosomes as Advanced Therapeutics for Inflammation: Current Progress and Future Perspectives
Yanjuan Song, Jing Hu, Chunlian Ma, Hua Liu, Zhanghua Li & Yi Yang
Pages: 1597-1627
Published online: 18 Feb 2024
AbstractforMacrophage-Derived Exosomes as Advanced Therapeutics for Inflammation: Current Progress and Future Perspectives | Full Text | References | PDF (8.7 MB) | EPUB
  • 322 Views
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Review
Microstructure Formation and Characterization of Long-Acting Injectable Microspheres: The Gateway to Fully Controlled Drug Release Pattern
Mengdi Wang, Shan Wang, Changhao Zhang, Ming Ma, Bohua Yan, Xinming Hu, Tianjiao Shao, Yan Piao, Lili Jin & Jing Gao
Pages: 1571-1595
Published online: 19 Feb 2024
AbstractforMicrostructure Formation and Characterization of Long-Acting Injectable Microspheres: The Gateway to Fully Controlled Drug Release Pattern | Full Text | References | PDF (10.7 MB) | EPUB
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Article
Fructus Xanthii and Magnolia liliiflora Volatile Oils Liposomes-Loaded Thermosensitive in situ Gel for Allergic Rhinitis Management
Zhongxu Jing, Wenqing Li, Wei Liao, Ying Lv, Yuwei Liu, Haibo Jiang & Yufei Feng
Pages: 1557-1570
Published online: 18 Feb 2024
AbstractforFructus Xanthii and Magnolia liliiflora Volatile Oils Liposomes-Loaded Thermosensitive in situ Gel for Allergic Rhinitis Management | Full Text | References | PDF (5.8 MB) | EPUB
  • 123 Views
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Article
Hydrogels Containing Chitosan-Modified Gold Nanoparticles Show Significant Efficacy in Healing Diabetic Wounds Infected with Antibiotic-Resistant Bacteria
Hongqi Meng, Ying Zhao, Hang Cai, Di You, Ying Wang, Siyu Wu, Yixin Wang, Wenlai Guo & Wenrui Qu
Pages: 1539-1556
Published online: 18 Feb 2024
AbstractforHydrogels Containing Chitosan-Modified Gold Nanoparticles Show Significant Efficacy in Healing Diabetic Wounds Infected with Antibiotic-Resistant Bacteria | Full Text | References | PDF (15.5 MB) | EPUB
  • 267 Views
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REVIEW

Review
Opportunities and Challenges for Inhalable Nanomedicine Formulations in Respiratory Diseases: A Review
Xujun Feng, Yuan Shi, Ye Zhang, Fei Lei, Rong Ren & Xiangdong Tang
Pages: 1509-1538
Published online: 16 Feb 2024
AbstractforOpportunities and Challenges for Inhalable Nanomedicine Formulations in Respiratory Diseases: A Review | Full Text | References | PDF (16.4 MB) | EPUB
  • 431 Views
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Article
Nanofabrications of Erythrocyte Membrane-Coated Telmisartan Delivery System Effective for Radiosensitivity of Tumor Cells in Mice Model
Shaoqing Chen, Cheng Wang, Yanyan Meng, Pengyin Li, Yiwen Pan, Mu He & Xinye Ni
Pages: 1487-1508
Published online: 15 Feb 2024
AbstractforNanofabrications of Erythrocyte Membrane-Coated Telmisartan Delivery System Effective for Radiosensitivity of Tumor Cells in Mice Model | Full Text | References | PDF (19 MB) | EPUB
  • 116 Views
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Article
High Antiparasitic and Antimicrobial Performance of Biosynthesized NiO Nanoparticles via Wasted Olive Leaf Extract
Samia Q Alghamdi, NF Alotaibi, Sameera N Al-Ghamdi, Laila S Alqarni, Touseef Amna, Shaima MN Moustafa, Ibrahim Hotan Alsohaimi, IA Alruwaili & AM Nassar
Pages: 1469-1485
Published online: 14 Feb 2024
AbstractforHigh Antiparasitic and Antimicrobial Performance of Biosynthesized NiO Nanoparticles via Wasted Olive Leaf Extract | Full Text | References | PDF (8.3 MB) | EPUB
  • 233 Views
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Article
Extracellular Vesicles Maintain Blood-Brain Barrier Integrity by the Suppression of Caveolin-1/CD147/VEGFR2/MMP Pathway After Ischemic Stroke
Yiyang Li, Jiali Chen, Xingping Quan, Ying Chen, Yan Han, Jinfen Chen, Li Yang, Youhua Xu, Xu Shen, Ruibing Wang & Yonghua Zhao
Pages: 1451-1467
Published online: 26 Feb 2024
AbstractforExtracellular Vesicles Maintain Blood-Brain Barrier Integrity by the Suppression of Caveolin-1/CD147/VEGFR2/MMP Pathway After Ischemic Stroke | Full Text | References | PDF (10.8 MB) | EPUB
  • 175 Views
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Article
Nasal Administration of bFGF-Loaded Nanoliposomes Attenuates Neuronal Injury and Cognitive Deficits in Mice with Vascular Dementia Induced by Repeated Cerebral Ischemia‒Reperfusion
Ming Zhang, Shuai-shuai Huang, Wen-yue He, Wei-juan Cao, Min-yi Sun & Ning-wei Zhu
Pages: 1431-1450
Published online: 26 Feb 2024
AbstractforNasal Administration of bFGF-Loaded Nanoliposomes Attenuates Neuronal Injury and Cognitive Deficits in Mice with Vascular Dementia Induced by Repeated Cerebral Ischemia‒Reperfusion | Full Text | References | PDF (11.6 MB) | EPUB
  • 117 Views
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Article
Hypoxic Bone Mesenchymal Stem Cell-Derived Exosomes Direct Schwann Cells Proliferation, Migration, and Paracrine to Accelerate Facial Nerve Regeneration via circRNA_Nkd2/miR-214-3p/MED19 Axis
Haopeng Wang, Hua Zhao, Zheng Chen, Xiaomin Cai, Xuhui Wang, Ping Zhou, Yinda Tang, Tingting Ying, Xin Zhang, Yiman Shen, Baimiao Wang, Wanchun Zhu, Jin Zhu, Xinjun Wang & Shiting Li
Pages: 1409-1429
Published online: 11 Feb 2024
AbstractforHypoxic Bone Mesenchymal Stem Cell-Derived Exosomes Direct Schwann Cells Proliferation, Migration, and Paracrine to Accelerate Facial Nerve Regeneration via circRNA_Nkd2/miR-214-3p/MED19 Axis | Full Text | References | PDF (14.1 MB) | EPUB
  • 161 Views
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Article
Artesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects
Jiaxing Zhang, Liwei Gu, Yumao Jiang, Yun Ma, Ziyue Zhang, Shengnan Shen, Shuo Shen, Qing Peng & Wei Xiao
Pages: 1385-1408
Published online: 11 Feb 2024
AbstractforArtesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects | Full Text | References | PDF (20.1 MB) | EPUB
  • 247 Views
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Review
Bone Targeting Nanoparticles for the Treatment of Osteoporosis
Caining Wen, Xiao Xu, Yuanmin Zhang, Jiang Xia, Yujie Liang & Limei Xu
Pages: 1363-1383
Published online: 11 Feb 2024
AbstractforBone Targeting Nanoparticles for the Treatment of Osteoporosis | Full Text | References | PDF (4.1 MB) | EPUB
  • 316 Views
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Article
Prediction of Response to Chemoradiotherapy by Dynamic Changes of Circulating Exosome Levels in Patients with Esophageal Squamous Cell Carcinoma
Chuanfeng Zhang, Zhen Guo & Zhao Jing
Pages: 1351-1362
Published online: 09 Feb 2024
AbstractforPrediction of Response to Chemoradiotherapy by Dynamic Changes of Circulating Exosome Levels in Patients with Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (3.2 MB) | EPUB
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Article
Critical Evaluation of Green Synthesized Silver Nanoparticles-Kaempferol for Antibacterial Activity Against Methicillin-Resistant Staphylococcus aureus
Ariff Haikal Hairil Anuar, Siti Aisyah Abd Ghafar, Rohazila Mohamad Hanafiah, Vuanghao Lim & Nur Farah Atiqah Mohd Pazli
Pages: 1339-1350
Published online: 08 Feb 2024
AbstractforCritical Evaluation of Green Synthesized Silver Nanoparticles-Kaempferol for Antibacterial Activity Against Methicillin-Resistant Staphylococcus aureus | Full Text | References | PDF (5.1 MB) | EPUB
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Review
The Physiological Inorganic Polymers Biosilica and Polyphosphate as Key Drivers for Biomedical Materials in Regenerative Nanomedicine
Werner EG Müller, Meik Neufurth, Shunfeng Wang, Heinz C Schröder & Xiaohong Wang
Pages: 1303-1337
Published online: 08 Feb 2024
AbstractforThe Physiological Inorganic Polymers Biosilica and Polyphosphate as Key Drivers for Biomedical Materials in Regenerative Nanomedicine | Full Text | References | PDF (16.1 MB) | EPUB
  • 209 Views
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Article
PLGA-Chitosan Encapsulated IL-10 Nanoparticles Modulate Chlamydia Inflammation in Mice
Abebayehu N Yilma, Rajnish Sahu, Praseetha Subbarayan, Francois Villinger, Mamie T Coats, Shree R Singh & Vida A Dennis
Pages: 1287-1301
Published online: 08 Feb 2024
AbstractforPLGA-Chitosan Encapsulated IL-10 Nanoparticles Modulate Chlamydia Inflammation in Mice | Full Text | References | PDF (6.6 MB) | EPUB
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Article
Anti-Microbial Effect of AgBr-NP@CTMAB on Streptococcus Mutans and Assessment of Surface Roughness Hardness and Flexural Strength of PMMA
Jing-Jing Huang, Lin Jia, Qiao-Jun Zhang, Hao-Hong Li, Da-Li Zheng & Ming Zheng
Pages: 1273-1285
Published online: 08 Feb 2024
AbstractforAnti-Microbial Effect of AgBr-NP@CTMAB on Streptococcus Mutans and Assessment of Surface Roughness Hardness and Flexural Strength of PMMA | Full Text | References | PDF (6.5 MB) | EPUB
  • 92 Views
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Article
Precision USPIO-PEG-SLex Nanotheranostic Agent Targeted Photothermal Therapy for Enhanced Anti-PD-L1 Immunotherapy to Treat Immunotherapy Resistance
Ting Li, Lianshan Guo, Jiaxu Li, Xingyu Mu, Lijuan Liu, Shulin Song, Ningbin Luo, Qi Zhang, Bin Zheng & Guanqiao Jin
Pages: 1249-1272
Published online: 06 Feb 2024
AbstractforPrecision USPIO-PEG-SLex Nanotheranostic Agent Targeted Photothermal Therapy for Enhanced Anti-PD-L1 Immunotherapy to Treat Immunotherapy Resistance | Full Text | References | PDF (18.9 MB) | EPUB
  • 151 Views
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Article
Gel-Dispersed Nanostructured Lipid Carriers Loading Thymol Designed for Dermal Pathologies
Camila Folle, Ana M Marqués, Natalia Díaz-Garrido, Paulina Carvajal-Vidal, Elena Sánchez López, Joaquim Suñer-Carbó, Lyda Halbaut, Mireia Mallandrich, Marta Espina, Josefa Badia, Laura Baldoma, Maria Luisa García & Ana Cristina Calpena
Pages: 1225-1248
Published online: 06 Feb 2024
AbstractforGel-Dispersed Nanostructured Lipid Carriers Loading Thymol Designed for Dermal Pathologies | Full Text | References | PDF (10.1 MB) | EPUB
  • 196 Views
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Article
Combined ROS Responsive Polydopamine-Coated Berberine Nanoparticles Effective Against Ulcerative Colitis in Mouse Model
Chenqi Chang, Heng Liu, Xiaotong Li, Dandan Song, Yue Liu, Chang Lu, Yu Zhen, Ying Chen, Jinguo Xu, Weidong Li, Xiaobin Jia, Zhipeng Chen & Rui Chen
Pages: 1205-1224
Published online: 07 Feb 2024
AbstractforCombined ROS Responsive Polydopamine-Coated Berberine Nanoparticles Effective Against Ulcerative Colitis in Mouse Model | Full Text | References | PDF (14.1 MB) | EPUB
  • 169 Views
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Review
Plant-Derived Exosome-Like Nanoparticles: Emerging Nanosystems for Enhanced Tissue Engineering
Hui Feng, Yang Yue, Yan Zhang, Jingqi Liang, Liang Liu, Qiong Wang, Qian Feng & Hongmou Zhao
Pages: 1189-1204
Published online: 06 Feb 2024
AbstractforPlant-Derived Exosome-Like Nanoparticles: Emerging Nanosystems for Enhanced Tissue Engineering | Full Text | References | PDF (9 MB) | EPUB
  • 381 Views
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Article
Revolutionizing Psoriasis Topical Treatment: Enhanced Efficacy Through Ceramide/Phospholipid Composite Cerosomes Co-Delivery of Cyclosporine and Dithranol: In-Vitro, Ex-Vivo, and in-Vivo Studies
Sammar Fathy Elhabal, Nashwa Abdelaal, Saeed AS Al-Zuhairy, Mohamed Fathi Mohamed Elrefai, Mohamed Mansour Khalifa, Mohammad Ahmad Khasawneh, Ahmed Mohsen Elsaid Hamdan, Passant M Mohie, Rania A Gad, Soad L Kabil, Mohamed Kandeel El-Ashery, Bhaskara R Jasti, Nahla A Elzohairy, Nehal Elfar, Tayseer Elnawawy, Fatma E Hassan & Mohamed Ahmed El-Nabarawi
Pages: 1163-1187
Published online: 07 Feb 2024
AbstractforRevolutionizing Psoriasis Topical Treatment: Enhanced Efficacy Through Ceramide/Phospholipid Composite Cerosomes Co-Delivery of Cyclosporine and Dithranol: In-Vitro, Ex-Vivo, and in-Vivo Studies | Full Text | References | PDF (13.2 MB) | EPUB
  • 454 Views
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Article
Controlled siRNA Release of Nanopolyplex for Effective Targeted Anticancer Therapy in Animal Model
Jingchao Jia, Jing Yang, Leimin Qian, Biao Zhou, Xiaodong Tang, Shuanghai Liu, Li Wu, Jifeng Chen & Yuting Kuang
Pages: 1145-1161
Published online: 06 Feb 2024
AbstractforControlled siRNA Release of Nanopolyplex for Effective Targeted Anticancer Therapy in Animal Model | Full Text | References | PDF (12.6 MB) | EPUB
  • 139 Views
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REVIEW

Review
Recent Advances in Understanding the Molecular Mechanisms of Multidrug Resistance and Novel Approaches of CRISPR/Cas9-Based Genome-Editing to Combat This Health Emergency
Khaled S Allemailem
Pages: 1125-1143
Published online: 06 Feb 2024
AbstractforRecent Advances in Understanding the Molecular Mechanisms of Multidrug Resistance and Novel Approaches of CRISPR/Cas9-Based Genome-Editing to Combat This Health Emergency | Full Text | References | PDF (9.7 MB) | EPUB
  • 515 Views
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Article
Synthesis and Characterization of Graphene Oxide/Polyethylene Glycol/Folic Acid/Brucine Nanocomposites and Their Anticancer Activity on HepG2 Cells
Ibrahim Abdel Aziz Ibrahim, Abdullah R Alzahrani, Ibrahim M Alanazi, Naiyer Shahzad, Imran Shahid, Alaa Hisham Falemban, Mohd Fahami Nur Azlina & Palanisamy Arulselvan
Pages: 1109-1124
Published online: 04 Feb 2024
AbstractforSynthesis and Characterization of Graphene Oxide/Polyethylene Glycol/Folic Acid/Brucine Nanocomposites and Their Anticancer Activity on HepG2 Cells | Full Text | References | PDF (11.5 MB) | EPUB
  • 172 Views
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Article
Dipsacus Asperoides-Derived Exosomes-Like Nanoparticles Inhibit the Progression of Osteosarcoma via Activating P38/JNK Signaling Pathway
Jiaxu Lu, Jiaxian Chen, Junhong Ye, Zhen Shi, Xiang Gao, Peicong Chen, Yanzhou Chang, Hao Lin & Peng Li
Pages: 1097-1108
Published online: 01 Feb 2024
AbstractforDipsacus Asperoides-Derived Exosomes-Like Nanoparticles Inhibit the Progression of Osteosarcoma via Activating P38/JNK Signaling Pathway | Full Text | References | PDF (7.4 MB) | EPUB
  • 155 Views
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Article
Donepezil-Loaded Nanocarriers for the Treatment of Alzheimer’s Disease: Superior Efficacy of Extracellular Vesicles Over Polymeric Nanoparticles
Rummenigge Oliveira Silva, Hermine Counil, Jean-Michel Rabanel, Mohamed Haddad, Charlotte Zaouter, Mohamed Raâfet Ben Khedher, Shunmoogum A Patten & Charles Ramassamy
Pages: 1077-1096
Published online: 31 Jan 2024
AbstractforDonepezil-Loaded Nanocarriers for the Treatment of Alzheimer’s Disease: Superior Efficacy of Extracellular Vesicles Over Polymeric Nanoparticles | Full Text | References | PDF (7.7 MB) | EPUB
  • 375 Views
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REVIEW

Review
Regulating Cholesterol in Tumorigenesis: A Novel Paradigm for Tumor Nanotherapeutics
Huifeng Wu, Xiaodong Wu, Mengdan Zhao, Jingjing Yan, Chaoqun Li, Zhewei Zhang, Sangsang Tang, Rong Wang & Weidong Fei
Pages: 1055-1076
Published online: 01 Feb 2024
AbstractforRegulating Cholesterol in Tumorigenesis: A Novel Paradigm for Tumor Nanotherapeutics | Full Text | References | PDF (9.8 MB) | EPUB
  • 232 Views
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Article
TiO2-Ti3C2 Nanocomposites Utilize Their Photothermal Activity for Targeted Treatment of Colorectal Cancer
Zhenlei Wang, Zengci Run, Huamin Wang, Xiaojun He & Jian Li
Pages: 1041-1054
Published online: 31 Jan 2024
AbstractforTiO2-Ti3C2 Nanocomposites Utilize Their Photothermal Activity for Targeted Treatment of Colorectal Cancer | Full Text | References | PDF (12.8 MB) | EPUB
  • 161 Views
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Review
Anticancer Mechanisms and Potential Anticancer Applications of Antimicrobial Peptides and Their Nano Agents
Ziyi Dong, Xinyu Zhang, Qing Zhang, Jakkree Tangthianchaichana, Mingxue Guo, Shouying Du & Yang Lu
Pages: 1017-1039
Published online: 31 Jan 2024
AbstractforAnticancer Mechanisms and Potential Anticancer Applications of Antimicrobial Peptides and Their Nano Agents | Full Text | References | PDF (4.8 MB) | EPUB
  • 292 Views
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Article
Dexamethasone-Loaded Lipid Calcium Phosphate Nanoparticles Treat Experimental Colitis by Regulating Macrophage Polarization in Inflammatory Sites
Kai Dong, Ying Zhang, Hong Rui Ji, Ze Lin Guan, Dan Yang Wang, Zi Yang Guo, Shu Jing Deng, Bin Yang He, Jian Feng Xing & Cui Yu You
Pages: 993-1016
Published online: 27 Jan 2024
AbstractforDexamethasone-Loaded Lipid Calcium Phosphate Nanoparticles Treat Experimental Colitis by Regulating Macrophage Polarization in Inflammatory Sites | Full Text | References | PDF (13.1 MB) | EPUB
  • 254 Views
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REVIEW

Review
Metal Nanoparticles: Advanced and Promising Technology in Diabetic Wound Therapy
Qinzhou Zheng, Cuimin Chen, Yong Liu, Jie Gao, Luxin Li, Chuan Yin & Xiaohuan Yuan
Pages: 965-992
Published online: 27 Jan 2024
AbstractforMetal Nanoparticles: Advanced and Promising Technology in Diabetic Wound Therapy | Full Text | References | PDF (10.4 MB) | EPUB
  • 440 Views
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Review
Research Progress of SN38 Drug Delivery System in Cancer Treatment
Qing-rui Qi, Huan Tian, Bao-sen Yue, Bing-tao Zhai & Feng Zhao
Pages: 945-964
Published online: 26 Jan 2024
AbstractforResearch Progress of SN38 Drug Delivery System in Cancer Treatment | Full Text | References | PDF (616.9 KB) | EPUB
  • 417 Views
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Review
Nanoplatform-Mediated Autophagy Regulation and Combined Anti-Tumor Therapy for Resistant Tumors
Caixia Yang, Yuan Ding, Zhengwei Mao & Weilin Wang
Pages: 917-944
Published online: 26 Jan 2024
AbstractforNanoplatform-Mediated Autophagy Regulation and Combined Anti-Tumor Therapy for Resistant Tumors | Full Text | References | PDF (6.4 MB) | EPUB
  • 213 Views
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Article
Combined Placental Mesenchymal Stem Cells with Guided Nanoparticles Effective Against Diabetic Nephropathy in Mouse Model
Ke Wang, Te Liu, Yucheng Zhang, Huiying Lv, Hua Yao, Ye Zhao, Jing Li & Xiuying Li
Pages: 901-915
Published online: 25 Jan 2024
AbstractforCombined Placental Mesenchymal Stem Cells with Guided Nanoparticles Effective Against Diabetic Nephropathy in Mouse Model | Full Text | References | PDF (14.5 MB) | EPUB
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REVIEW

Review
Hydrogel Loaded with Components for Therapeutic Applications in Hypertrophic Scars and Keloids
Yixiu Zhong, Youfan Zhang, Beibei Lu, Zhenjun Deng, Zhiwen Zhang, Qi Wang & Jianglin Zhang
Pages: 883-899
Published online: 25 Jan 2024
AbstractforHydrogel Loaded with Components for Therapeutic Applications in Hypertrophic Scars and Keloids | Full Text | References | PDF (6.8 MB) | EPUB
  • 280 Views
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Review
Recent Development and Applications of Polydopamine in Tissue Repair and Regeneration Biomaterials
Kai Guo, Yong Wang, Zi-Xuan Feng, Xiao-Ying Lin, Zhang-Rui Wu, Xin-Cao Zhong, Ze-Ming Zhuang, Tao Zhang, Jian Chen & Wei-Qiang Tan
Pages: 859-881
Published online: 25 Jan 2024
AbstractforRecent Development and Applications of Polydopamine in Tissue Repair and Regeneration Biomaterials | Full Text | References | PDF (10.7 MB) | EPUB
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ORIGINAL RESEARCH

Article
A One Step Strategy Based on Hollow Gold Nanoparticles to Detect C-Reactive Protein with High Sensitivity (Hs-CRP) in Serum for Monitoring Cardiovascular Disease
Changyou Luo, Ruiqing Zhang, Ji Liu, Xingyue He, Shengzhou Li, Chuanjiang Ran, Songbo Ma & Yan Shen
Pages: 845-858
Published online: 25 Jan 2024
AbstractforA One Step Strategy Based on Hollow Gold Nanoparticles to Detect C-Reactive Protein with High Sensitivity (Hs-CRP) in Serum for Monitoring Cardiovascular Disease | Full Text | References | PDF (5.1 MB) | EPUB
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REVIEW

Review
Nanosuspension-Based Drug Delivery Systems for Topical Applications
Mohamed Mahmud E Aldeeb, Gofarana Wilar, Cecep Suhandi, Khaled M Elamin & Nasrul Wathoni
Pages: 825-844
Published online: 25 Jan 2024
AbstractforNanosuspension-Based Drug Delivery Systems for Topical Applications | Full Text | References | PDF (1.9 MB) | EPUB
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Review
Recent Advances of Emerging Metal-Containing Two-Dimensional Nanomaterials in Tumor Theranostics
Chenxi Li, Xueyang Fang, Han Zhang & Bin Zhang
Pages: 805-824
Published online: 24 Jan 2024
AbstractforRecent Advances of Emerging Metal-Containing Two-Dimensional Nanomaterials in Tumor Theranostics | Full Text | References | PDF (14.1 MB) | EPUB
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ORIGINAL RESEARCH

Article
Preparation, Characterization, and Anti-Lung Cancer Activity of Tetrandrine-Loaded Stealth Liposomes
Zhengyu Fang, Peihong Lin, Rui Gao, Wenjing Yang, Aizhen Zhou & Wenying Yu
Pages: 787-803
Published online: 24 Jan 2024
AbstractforPreparation, Characterization, and Anti-Lung Cancer Activity of Tetrandrine-Loaded Stealth Liposomes | Full Text | References | PDF (14.2 MB) | EPUB
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REVIEW

Review
Bacteria-Based Nanoprobes for Cancer Therapy
Yiping Lu, Nan Mei, Yinwei Ying, Dongdong Wang, Xuanxuan Li, Yajing Zhao, Yuqi Zhu, Shun Shen & Bo Yin
Pages: 759-785
Published online: 23 Jan 2024
AbstractforBacteria-Based Nanoprobes for Cancer Therapy | Full Text | References | PDF (9 MB) | EPUB
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ORIGINAL RESEARCH

Article
Engineered Exosomes Carrying miR-588 for Treatment of Triple Negative Breast Cancer Through Remodeling the Immunosuppressive Microenvironment
Zhengjia Zhang, Xinyi Luo, Xiaoxia Xue, Mingshi Pang, Xiangpeng Wang, Liuchunyang Yu, Jinxiu Qian, Xiaoyu Li, Meng Tian, Aiping Lu, Cheng Lu & Yuanyan Liu
Pages: 743-758
Published online: 23 Jan 2024
AbstractforEngineered Exosomes Carrying miR-588 for Treatment of Triple Negative Breast Cancer Through Remodeling the Immunosuppressive Microenvironment | Full Text | References | PDF (9.5 MB) | EPUB
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Article
Sequentially Released Liposomes Enhance Anti-Liver Cancer Efficacy of Tetrandrine and Celastrol-Loaded Coix Seed Oil
Yunyan Chen, Ziwei Zhang, Zhilei Qian, Rui Ma, Minna Luan & Yu Sun
Pages: 727-742
Published online: 22 Jan 2024
AbstractforSequentially Released Liposomes Enhance Anti-Liver Cancer Efficacy of Tetrandrine and Celastrol-Loaded Coix Seed Oil | Full Text | References | PDF (13.9 MB) | EPUB
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Article
A pH-Sensitive Nanoparticle as Reactive Oxygen Species Amplifier to Regulate Tumor Microenvironment and Potentiate Tumor Radiotherapy
Xiaomei Jiang, Xiaohong Jiang, Dongjie Wu, Wanzhu Xie, Xiong Liu & Jintao Zheng
Pages: 709-725
Published online: 22 Jan 2024
AbstractforA pH-Sensitive Nanoparticle as Reactive Oxygen Species Amplifier to Regulate Tumor Microenvironment and Potentiate Tumor Radiotherapy | Full Text | References | PDF (13.1 MB) | EPUB
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Article
Synergistic Combination of an Intelligent Nanozyme and Radiotherapy for Treating Renal Cancer
Lei Lei & Ke Wang
Pages: 699-707
Published online: 22 Jan 2024
AbstractforSynergistic Combination of an Intelligent Nanozyme and Radiotherapy for Treating Renal Cancer | Full Text | References | PDF (7.8 MB) | EPUB
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SHORT REPORT

Brief Report
Intratumoral Treatment of Melanoma Tumors with Large Surface Area Microparticle Paclitaxel and Synergy with Immune Checkpoint Inhibition
Holly A Maulhardt, Alyson M Marin & Gere S diZerega
Pages: 689-697
Published online: 21 Jan 2024
AbstractforIntratumoral Treatment of Melanoma Tumors with Large Surface Area Microparticle Paclitaxel and Synergy with Immune Checkpoint Inhibition | Full Text | References | PDF (3 MB) | EPUB
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ORIGINAL RESEARCH

Article
Preparation of Budesonide-Loaded Liposomal Nanoparticles for Pulmonary Delivery and Their Therapeutic Effect in OVA-Induced Asthma in Mice
Xu Zuo, Yinuo Gu, Xiaoping Guo, Wenxue Zheng, Haoyu Zheng, Yiming An, Caina Xu & Fang Wang
Pages: 673-688
Published online: 20 Jan 2024
AbstractforPreparation of Budesonide-Loaded Liposomal Nanoparticles for Pulmonary Delivery and Their Therapeutic Effect in OVA-Induced Asthma in Mice | Full Text | References | PDF (13.1 MB) | EPUB
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Article
Magnesium-Doped Nano-Hydroxyapatite/Polyvinyl Alcohol/Chitosan Composite Hydrogel: Preparation and Characterization
Kui Zhang, Yan Liu, Zhenrui Zhao, Xuewen Shi, Ruihao Zhang, Yixiang He, Huaibin Zhang & Wenji Wang
Pages: 651-671
Published online: 19 Jan 2024
AbstractforMagnesium-Doped Nano-Hydroxyapatite/Polyvinyl Alcohol/Chitosan Composite Hydrogel: Preparation and Characterization | Full Text | References | PDF (20 MB) | EPUB
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Article
Specific Targeting of Mesothelin-Expressing Malignant Cells Using Nanobody-Functionalized Magneto-Fluorescent Nanoassemblies
Tina Briolay, Judith Fresquet, Damien Meyer, Brigitte Kerfelec, Patrick Chames, Eléna Ishow & Christophe Blanquart
Pages: 633-650
Published online: 19 Jan 2024
AbstractforSpecific Targeting of Mesothelin-Expressing Malignant Cells Using Nanobody-Functionalized Magneto-Fluorescent Nanoassemblies | Full Text | References | PDF (7.6 MB) | EPUB
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Article
Effect of C7-3-Peptide-Loaded Chitosan Nanoparticles Against Multi-Drug-Resistant Neisseria gonorrhoeae
Asma Ismail Albdrawy, Fadilah Sfouq Aleanizy, Esraa Kamal Eltayb, Abdullah A Aldossari, Mohammed M Alanazi, Rihaf Alfaraj, Eram Eltahir, Hibah M Albasri, Jouri S Alanazi & Fulwah Yahya Alqahtani
Pages: 609-631
Published online: 18 Jan 2024
AbstractforEffect of C7-3-Peptide-Loaded Chitosan Nanoparticles Against Multi-Drug-Resistant Neisseria gonorrhoeae | Full Text | References | PDF (9.2 MB) | EPUB
  • 218 Views
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REVIEW

Review
Biomimetic Nano-Drug Delivery System: An Emerging Platform for Promoting Tumor Treatment
Xiujuan Han, Chunai Gong, Qingru Yang, Kaile Zheng, Zhuo Wang & Wei Zhang
Pages: 571-608
Published online: 18 Jan 2024
AbstractforBiomimetic Nano-Drug Delivery System: An Emerging Platform for Promoting Tumor Treatment | Full Text | References | PDF (23.4 MB) | EPUB
  • 780 Views
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Review
Nano-Drug Delivery Systems Based on Natural Products
Ying Lv, Wenqing Li, Wei Liao, Haibo Jiang, Yuwei Liu, Jiansheng Cao, Wenfei Lu & Yufei Feng
Pages: 541-569
Published online: 17 Jan 2024
AbstractforNano-Drug Delivery Systems Based on Natural Products | Full Text | References | PDF (9.7 MB) | EPUB
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ORIGINAL RESEARCH

Article
A Targeted Multi-Crystalline Manganese Oxide as a Tumor-Selective Nano-Sized MRI Contrast Agent for Early and Accurate Diagnosis of Tumors
Gongxin Yang, Jikai Xia, Xiaoqing Dai, Hongbo Zhao, Weiqing Gao, Weilong Ding, Xiaofeng Tao & Ling Zhu
Pages: 527-540
Published online: 17 Jan 2024
AbstractforA Targeted Multi-Crystalline Manganese Oxide as a Tumor-Selective Nano-Sized MRI Contrast Agent for Early and Accurate Diagnosis of Tumors | Full Text | References | PDF (11.1 MB) | EPUB
  • 139 Views
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Article
Efficacy and Mechanism of a Biomimetic Nanosystem Carrying Doxorubicin and an IDO Inhibitor for Treatment of Advanced Triple-Negative Breast Cancer
Chuling Hu, Yan Liu, Wei Cao, Na Li, Shen Gao, Zhuo Wang & Fenfen Gu
Pages: 507-526
Published online: 17 Jan 2024
AbstractforEfficacy and Mechanism of a Biomimetic Nanosystem Carrying Doxorubicin and an IDO Inhibitor for Treatment of Advanced Triple-Negative Breast Cancer | Full Text | References | PDF (18 MB) | EPUB
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Article
Empowering Cartilage Restructuring with Biodegradable Magnesium Doped-Silicon Based-Nanoplatforms: Sustained Delivery and Enhanced Differentiation Potential
Min Chen, Tao Liu, Wenqiang Li, Yingting Li, Puxin Zhong, Huanchen Yan, Jingyin Kong & Weixiang Liang
Pages: 491-506
Published online: 17 Jan 2024
AbstractforEmpowering Cartilage Restructuring with Biodegradable Magnesium Doped-Silicon Based-Nanoplatforms: Sustained Delivery and Enhanced Differentiation Potential | Full Text | References | PDF (14.1 MB) | EPUB
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CORRIGENDUM

Correction
Advances in Formulations of Microneedle System for Rheumatoid Arthritis Treatment [Corrigendum]
Pages: 489-490
Published online: 17 Jan 2024
CitationforAdvances in Formulations of Microneedle System for Rheumatoid Arthritis Treatment [Corrigendum] | Full Text | PDF (235.6 KB) | EPUB
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ORIGINAL RESEARCH

Article
Bone-Targeting Peptide and RNF146 Modified Apoptotic Extracellular Vesicles Alleviate Osteoporosis
Linyuan Gui, Qingyuan Ye, Lu Yu, Geng Dou, Yang Zhou, Yang Liu, Yanqi Zhang, Xiaoshan Yang, Fang Jin, Shiyu Liu, Yan Jin & Lili Ren
Pages: 471-488
Published online: 17 Jan 2024
AbstractforBone-Targeting Peptide and RNF146 Modified Apoptotic Extracellular Vesicles Alleviate Osteoporosis | Full Text | References | PDF (13.2 MB) | EPUB
  • 229 Views
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Article
Characterization, Synthesis, and Biological Activities of Silver Nanoparticles Produced via Green Synthesis Method Using Thymus Vulgaris Aqueous Extract
Umer Ejaz, Muhammad Afzal, Modasrah Mazhar, Muhammad Riaz, Naveed Ahmed, Waleed Y Rizg, Amerh Aiad Alahmadi, Moutaz Y Badr, Rayan Y Mushtaq & Chan Yean Yean
Pages: 453-469
Published online: 16 Jan 2024
AbstractforCharacterization, Synthesis, and Biological Activities of Silver Nanoparticles Produced via Green Synthesis Method Using Thymus Vulgaris Aqueous Extract | Full Text | References | PDF (5.9 MB) | EPUB
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REVIEW

Review
Application of the Peroxidase‒like Activity of Nanomaterials for the Detection of Pathogenic Bacteria and Viruses
Cheng Luo, Xianglong Li & Yan Li
Pages: 441-452
Published online: 15 Jan 2024
AbstractforApplication of the Peroxidase‒like Activity of Nanomaterials for the Detection of Pathogenic Bacteria and Viruses | Full Text | References | PDF (2.9 MB) | EPUB
  • 259 Views
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ORIGINAL RESEARCH

Article
Preclinical Activity of Two Paclitaxel Nanoparticle Formulations After Intraperitoneal Administration in Ovarian Cancer Murine Xenografts
Jesse Demuytere, Charlotte Carlier, Leen Van de Sande, Anne Hoorens, Kaat De Clercq, Silvia Giordano, Lavinia Morosi, Cristina Matteo, Massimo Zucchetti, Enrico Davoli, Jo Van Dorpe, Chris Vervaet & Wim Ceelen
Pages: 429-440
Published online: 16 Jan 2024
AbstractforPreclinical Activity of Two Paclitaxel Nanoparticle Formulations After Intraperitoneal Administration in Ovarian Cancer Murine Xenografts | Full Text | References | PDF (6.7 MB) | EPUB
  • 179 Views
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Article
Apoptotic Extracellular Vesicles Derived from Human Umbilical Vein Endothelial Cells Promote Skin Repair by Enhancing Angiogenesis: From Death to Regeneration
Jinzhao Liu, Jia Dong & Xibo Pei
Pages: 415-428
Published online: 15 Jan 2024
AbstractforApoptotic Extracellular Vesicles Derived from Human Umbilical Vein Endothelial Cells Promote Skin Repair by Enhancing Angiogenesis: From Death to Regeneration | Full Text | References | PDF (12.7 MB) | EPUB
  • 231 Views
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Article
Copper-Based Single-Atom Nanozyme System Mimicking Platelet Cells for Enhancing the Outcome of Radioimmunotherapy
Cheng Chen, Nandi Chen, Yan Qi, Meng Lyu, Chaoyan Wu, Conghua Xie & Haijun Yu
Pages: 403-414
Published online: 15 Jan 2024
AbstractforCopper-Based Single-Atom Nanozyme System Mimicking Platelet Cells for Enhancing the Outcome of Radioimmunotherapy | Full Text | References | PDF (10.1 MB) | EPUB
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Article
Development of a Magnetically-Assisted SERS Biosensor for Rapid Bacterial Detection
Siyun Cheng, Zhijie Tu, Shuai Zheng, Adeel Khan, Ping Yang, Han Shen & Bing Gu
Pages: 389-401
Published online: 15 Jan 2024
AbstractforDevelopment of a Magnetically-Assisted SERS Biosensor for Rapid Bacterial Detection | Full Text | References | PDF (9.1 MB) | EPUB
  • 279 Views
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REVIEW

Review
The Application of Nanovaccines in Autoimmune Diseases
Yuhong Tang & Lili Li
Pages: 367-388
Published online: 11 Jan 2024
AbstractforThe Application of Nanovaccines in Autoimmune Diseases | Full Text | References | PDF (7.6 MB) | EPUB
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ORIGINAL RESEARCH

Article
Magnesium Ion-Doped Mesoporous Bioactive Glasses Loaded with Gallic Acid Against Myocardial Ischemia/Reperfusion Injury by Affecting the Biological Functions of Multiple Cells
Wenpeng Yu, Jingli Ding, Jianfeng Chen, Ying Jiang, Jinping Zhao, Jichun Liu, Jianliang Zhou & Jinping Liu
Pages: 347-366
Published online: 11 Jan 2024
AbstractforMagnesium Ion-Doped Mesoporous Bioactive Glasses Loaded with Gallic Acid Against Myocardial Ischemia/Reperfusion Injury by Affecting the Biological Functions of Multiple Cells | Full Text | References | PDF (16.1 MB) | EPUB
  • 203 Views
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REVIEW

Review
A Promising Application of Injectable Hydrogels in Nerve Repair and Regeneration for Ischemic Stroke
Yuan Gao, Ting-Lin Zhang, Hong-Jian Zhang, Jie Gao & Peng-Fei Yang
Pages: 327-345
Published online: 11 Jan 2024
AbstractforA Promising Application of Injectable Hydrogels in Nerve Repair and Regeneration for Ischemic Stroke | Full Text | References | PDF (5.8 MB) | EPUB
  • 441 Views
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ORIGINAL RESEARCH

Article
A Pralidoxime Nanocomplex Formulation Targeting Transferrin Receptors for Reactivation of Brain Acetylcholinesterase After Exposure of Mice to an Anticholinesterase Organophosphate
Kathleen F Pirollo, Manish Moghe, Miaoyin Guan, Antonina S Rait, Aibing Wang, Sang-Soo Kim, Esther H Chang & Joe B Harford
Pages: 307-326
Published online: 11 Jan 2024
AbstractforA Pralidoxime Nanocomplex Formulation Targeting Transferrin Receptors for Reactivation of Brain Acetylcholinesterase After Exposure of Mice to an Anticholinesterase Organophosphate | Full Text | References | PDF (5.8 MB) | EPUB
  • 191 Views
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REVIEW

Review
Drug-Coformer Loaded-Mesoporous Silica Nanoparticles: A Review of the Preparation, Characterization, and Mechanism of Drug Release
Arif Budiman, Yoga Windhu Wardhana, Ahmad Ainurofiq, Yuda Prasetya Nugraha, Ridhatul Qaivani, Siti Nazila Awaliyyah Lukmanul Hakim & Diah Lia Aulifa
Pages: 281-305
Published online: 11 Jan 2024
AbstractforDrug-Coformer Loaded-Mesoporous Silica Nanoparticles: A Review of the Preparation, Characterization, and Mechanism of Drug Release | Full Text | References | PDF (5.1 MB) | EPUB
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Article
Enhancing Dendritic Cell Activation Through Manganese-Coated Nanovaccine Targeting the cGAS-STING Pathway
Qiyu Wang, Ying Gao, Qiang Li, Ao He, Qinglin Xu & Yongbin Mou
Pages: 263-280
Published online: 11 Jan 2024
AbstractforEnhancing Dendritic Cell Activation Through Manganese-Coated Nanovaccine Targeting the cGAS-STING Pathway | Full Text | References | PDF (11.9 MB) | EPUB
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Article
Hypoxia and Singlet Oxygen Dual-Responsive Micelles for Photodynamic and Chemotherapy Therapy Featured with Enhanced Cellular Uptake and Triggered Cargo Delivery
Xuliang Guo, Lefei Han, Wenyu Chen, Huixin He, Weijin Zhang, Chaoqi Huang & Xiu Wang
Pages: 247-261
Published online: 11 Jan 2024
AbstractforHypoxia and Singlet Oxygen Dual-Responsive Micelles for Photodynamic and Chemotherapy Therapy Featured with Enhanced Cellular Uptake and Triggered Cargo Delivery | Full Text | References | PDF (11.3 MB) | EPUB
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Article
A TA/Cu2+ Nanoparticle Enhanced Carboxymethyl Chitosan-Based Hydrogel Dressing with Antioxidant Properties and Promoting Wound Healing
Yongjun Huang, Yong Chen, Guoyun Cheng, Wenqiang Li, Hongan Zhang, Chaoqun Yu, Jia Fang, Jieyi Zuo, Ying Li, Lei Xu & Dawei Sun
Pages: 231-245
Published online: 10 Jan 2024
AbstractforA TA/Cu2+ Nanoparticle Enhanced Carboxymethyl Chitosan-Based Hydrogel Dressing with Antioxidant Properties and Promoting Wound Healing | Full Text | References | PDF (14 MB) | EPUB
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Article
Repaglinide–Solid Lipid Nanoparticles in Chitosan Patches for Transdermal Application: Box–Behnken Design, Characterization, and In Vivo Evaluation
Hany SM Ali, Nader Namazi, Hossein M Elbadawy, Abdelaziz AA El-Sayed, Sameh A Ahmed, Rawan Bafail, Mohannad A Almikhlafi & Yaser M Alahmadi
Pages: 209-230
Published online: 10 Jan 2024
AbstractforRepaglinide–Solid Lipid Nanoparticles in Chitosan Patches for Transdermal Application: Box–Behnken Design, Characterization, and In Vivo Evaluation | Full Text | References | PDF (7.4 MB) | EPUB
  • 399 Views
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Article
Glucose-Regulated Protein 78 Targeting ICG and DOX Loaded Hollow Fe3O4 Nanoparticles for Hepatocellular Carcinoma Diagnosis and Therapy
Yushen Jin, Zhongquan Cheng, Zhu Yuan, Yang Du, Jie Tian & Bing Shao
Pages: 189-208
Published online: 08 Jan 2024
AbstractforGlucose-Regulated Protein 78 Targeting ICG and DOX Loaded Hollow Fe3O4 Nanoparticles for Hepatocellular Carcinoma Diagnosis and Therapy | Full Text | References | PDF (16.7 MB) | EPUB
  • 215 Views
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Article
SiRNF8 Delivered by DNA Framework Nucleic Acid Effectively Sensitizes Chemotherapy in Colon Cancer
Zhao Guo, Haoyun Song, Yingxia Tian, Jie Xu, Guokun Zhang, Yanan Guo, Rong Shen & Degui Wang
Pages: 171-188
Published online: 05 Jan 2024
AbstractforSiRNF8 Delivered by DNA Framework Nucleic Acid Effectively Sensitizes Chemotherapy in Colon Cancer | Full Text | References | PDF (11.2 MB) | EPUB
  • 189 Views
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Article
Targeted Delivery of Geraniol via Hyaluronic Acid-Conjugation Enhances Its Anti-Tumor Activity Against Prostate Cancer
Han Yu, Na Ning, Fujin He, Jiao Xu, Han Zhao, Shaofeng Duan & Yunqi Zhao
Pages: 155-169
Published online: 05 Jan 2024
AbstractforTargeted Delivery of Geraniol via Hyaluronic Acid-Conjugation Enhances Its Anti-Tumor Activity Against Prostate Cancer | Full Text | References | PDF (9.5 MB) | EPUB
  • 317 Views
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Article
Synergistic Effects of Nanoscale CaO2 Combined with PD-1 Inhibitors in the Treatment of Hepatocellular Carcinoma: A Promising Combination
Yingliang Wang, Shuguang Ju, Huimin Zhou, Yaowei Bai, Chen Zhou, Jiacheng Liu, Xiangjun Dong & Chuansheng Zheng
Pages: 137-154
Published online: 04 Jan 2024
AbstractforSynergistic Effects of Nanoscale CaO2 Combined with PD-1 Inhibitors in the Treatment of Hepatocellular Carcinoma: A Promising Combination | Full Text | References | PDF (13.5 MB) | EPUB
  • 123 Views
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REVIEW

Review
TME-Related Biomimetic Strategies Against Cancer
Cheng Peng, Yilin Xu, Jing Wu, Donghai Wu, Lili Zhou & Xinhua Xia
Pages: 109-135
Published online: 03 Jan 2024
AbstractforTME-Related Biomimetic Strategies Against Cancer | Full Text | References | PDF (2.7 MB) | EPUB
  • 470 Views
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ORIGINAL RESEARCH

Article
Iron-Based Nanovehicle Delivering Fin56 for Hyperthermia-Boosted Ferroptosis Therapy Against Osteosarcoma
Yiran Zhang, Qingcheng Song, Yueyao Zhang, Jiheng Xiao, Xiangtian Deng, Xin Xing, Hongzhi Hu & Yingze Zhang
Pages: 91-107
Published online: 03 Jan 2024
AbstractforIron-Based Nanovehicle Delivering Fin56 for Hyperthermia-Boosted Ferroptosis Therapy Against Osteosarcoma | Full Text | References | PDF (11.1 MB) | EPUB
  • 216 Views
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Article
Fe-Capsaicin Nanozymes Attenuate Sepsis-Induced Acute Lung Injury via NF-κB Signaling
Ruijie Wang, Quan Li, Pengxin Wu, Ke Ren, Yan Li, Yang Wang, Huadong Zhu & Chuanzhu Lv
Pages: 73-90
Published online: 26 Feb 2024
AbstractforFe-Capsaicin Nanozymes Attenuate Sepsis-Induced Acute Lung Injury via NF-κB Signaling | Full Text | References | PDF (16.4 MB) | EPUB
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Article
MMP-2 Responsive Peptide Hydrogel-Based Nanoplatform for Multimodal Tumor Therapy
Qing Zhang, Wenjun Hu, Mingxue Guo, Xinyu Zhang, Qin Zhang, Fengqi Peng, Liwen Yan, Zucheng Hu, Jakkree Tangthianchaichana, Yan Shen, Haiyan Hu, Shouying Du & Yang Lu
Pages: 53-71
Published online: 02 Jan 2024
AbstractforMMP-2 Responsive Peptide Hydrogel-Based Nanoplatform for Multimodal Tumor Therapy | Full Text | References | PDF (11.9 MB) | EPUB
  • 243 Views
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Article
Topical Application of Cell-Penetrating Peptide Modified Anti-VEGF Drug Alleviated Choroidal Neovascularization in Mice
Weinan Hu, Wenting Cai, Yan Wu, Chengda Ren, Donghui Yu, Tingting Li, Tianyi Shen, Ding Xu & Jing Yu
Pages: 35-51
Published online: 02 Jan 2024
AbstractforTopical Application of Cell-Penetrating Peptide Modified Anti-VEGF Drug Alleviated Choroidal Neovascularization in Mice | Full Text | References | PDF (14.2 MB) | EPUB
  • 245 Views
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REVIEW

Review
Nanoparticle-Facilitated Therapy: Advancing Tools in Peripheral Nerve Regeneration
Shaoyan Shi, Xuehai Ou & Deliang Cheng
Pages: 19-34
Published online: 02 Jan 2024
AbstractforNanoparticle-Facilitated Therapy: Advancing Tools in Peripheral Nerve Regeneration | Full Text | References | PDF (8.2 MB) | EPUB
  • 265 Views
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ORIGINAL RESEARCH

Article
Remineralization of Dentin with Cerium Oxide and Its Potential Use for Root Canal Disinfection
Yinlin Wang, Xinyue Zhang, Haiyan Zheng, Zihuai Zhou, Si Li, Jimin Jiang, Mingxing Li & Baiping Fu
Pages: 1-17
Published online: 29 Dec 2023
AbstractforRemineralization of Dentin with Cerium Oxide and Its Potential Use for Root Canal Disinfection | Full Text | References | PDF (12 MB) | EPUB
  • 375 Views
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