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Original Research

Delivery of dexamethasone from bioactive nanofiber matrices stimulates odontogenesis of human dental pulp cells through integrin/BMP/mTOR signaling pathways

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Pages 2557-2567 | Published online: 03 Jun 2016

References

  • SharmaSSikriVSharmaNKSharmaVMRegeneration of tooth pulp and dentin: trends and advancesAnn Neurosci20101713143
  • AboutIBotteroMJde DenatoPCampsJFranquinJCMitsiadisTAHuman dentin production in vitroExp Cell Res20002581334110912785
  • BohlKSShonJRutherfordBMooneyDJRole of synthetic extracellular matrix in development of engineered dental pulpJ Biomater Sci Polym Ed1998977497649686338
  • HoltgraveEADonathKResponse of odontoblast-like cells to hydroxyapatite ceramic granulesBiomaterials19951621551597734651
  • OhgushiHCaplanAIStem cell technology and bioceramics: from cell to gene engineeringJ Biomed Mater Res199948691392710556859
  • KimHWKimHEKnowlesJCProduction and potential of bioactive glass nanofibers as a next-generation biomaterialAdv Funct Mater2006161215291535
  • KimHWLeeHHChunGSBioactivity and osteoblast responses of novel biomedical nanocomposites of bioactive glass nanofiber filled poly(lactic acid)J Biomed Mater Res A200885365166317876800
  • KimHWSongJHKimHEBioactive glass nanofiber-collagen nanocomposite as a novel bone regeneration matrixJ Biomed Mater Res A200679369870516850456
  • SongJHKimHEKimHWCollagen-apatite nanocomposite membranes for guided bone regenerationJ Biomed Mater Res B Appl Biomater200783124825717385223
  • PrescottRSAlsaneaRFayadMIIn vivo generation of dental pulp-like tissue by using dental pulp stem cells, a collagen scaffold, and dentin matrix protein 1 after subcutaneous transplantation in miceJ Endod200834442142618358888
  • BaeWJMinKSKimJJKimJJKimHWKimECOdontogenic responses of human dental pulp cells to collagen/nanobioactive glass nanocompositesDent Mater201228121271127923031484
  • KimGHParkYDLeeSYOdontogenic stimulation of human dental pulp cells with bioactive nanocomposite fiberJ Biomater Appl201529685486625098335
  • JaiswalNHaynesworthSECaplanAIBruderSPOsteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitroJ Cell Biochem19976422953129027589
  • MartinsADuarteARFariaSMarquesAPReisRLNevesNMOsteogenic induction of hBMSCs by electrospun scaffolds with dexamethasone release functionalityBiomaterials201031225875588520452016
  • LiLZhouGWangYYangGDingSZhouSControlled dual delivery of BMP-2 and dexamethasone by nanoparticle-embedded electrospun nanofibers for the efficient repair of critical-sized rat calvarial defectBiomaterials20153721822925453952
  • El-FiqiAKimJHKimHWOsteoinductive fibrous scaffolds of biopolymer/mesoporous bioactive glass nanocarriers with excellent bioactivity and long-term delivery of osteogenic drugACS Appl Mater Interfaces2015721140115225531645
  • El-FiqiAKimHWMesoporous bioactive nanocarriers in electrospun biopolymer fibrous scaffolds designed for sequential drug deliveryRSC Adv20144944444452
  • KitagawaMUedaHIizukaSImmortalization and characterization of human dental pulp cells with odontoblastic differentiationArch Oral Biol200752872773117350587
  • JayantRDMcShaneMJSrivastavaRPolyelectrolyte-coated alginate microspheres as drug delivery carriers for dexamethasone releaseDrug Deliv200916633134019606947
  • PatilSDPapadmitrakopoulosFBurgessDJConcurrent delivery of dexamethasone and VEGF for localized inflammation control and angiogenesisJ Control Release20071171687917169457
  • WangQWangJXLuQHDetamoreMSBerklandCInjectable PLGA based colloidal gels for zero-order dexamethasone release in cranial defectsBiomaterials201031184980498620303585
  • HanksCTFangDSunZEdwardsCAButlerWTDentin-specific proteins in MDPC-23 cell lineEur J Oral Sci1998106suppl 12602669541235
  • NarayananKSrinivasRRamachandranAHaoJQuinnBGeorgeADifferentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1Proc Natl Acad Sci U S A20019884516452111287660
  • NakashimaKZhouXKunkelGThe novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formationCell20021081172911792318
  • HarrisHThe human alkaline phosphatases: what we know and what we don’t knowClin Chim Acta199018621331502178806
  • ShiXWangYVarshneyRRRenLGongYWangDAMicrosphere-based drug releasing scaffolds for inducing osteogenesis of human mesenchymal stem cells in vitroEur J Pharm Sci2010391–3596719895885
  • KimJJBaeWJKimJMMineralized polycaprolactone nanofibrous matrix for odontogenesis of human dental pulp cellsJ Biomater Appl20142871069107823839784
  • LeeSKLeeSKLeeSIEffect of calcium phosphate cements on growth and odontoblastic differentiation in human dental pulp cellsJ Endod20103691537154220728723
  • ZhangJParkYDBaeWJEffects of bioactive cements incorporating zinc-bioglass nanoparticles on odontogenic and angiogenic potential of human dental pulp cellsJ Biomater Appl201529795496425201908
  • DingSLiJRLuoCLiLYangGZhouSBSynergistic effect of released dexamethasone and surface nanoroughness on mesenchymal stem cell differentiationBiomater Sci201311010911100
  • ShresthaSDiogenesAKishenATemporal-controlled dexamethasone releasing chitosan nanoparticle system enhances odontogenic differentiation of stem cells from apical papillaJ Endod20154181253125825956605
  • YangCMJiangLQBuSJIntravitreal administration of dexamethasone-loaded PLGA-TPGS nanoparticles for the treatment of posterior segment diseasesJ Biomed Nanotechnol2013991617162323980509
  • ZhangLHLiYZhangCWangYSSongCXPharmacokinetics and tolerance study of intravitreal injection of dexamethasone-loaded nanoparticles in rabbitsInt J Nanomedicine2009417518319774116
  • HynesROIntegrins: bidirectional, allosteric signaling machinesCell2002110667368712297042
  • SchallerMDFAK and paxillin: regulators of N-cadherin adhesion and inhibitors of cell migration?J Cell Biol2004166215715915263014
  • MoghePVBerthiaumeFEzzellRMTonerMTompkinsRGYarmushMLCulture matrix configuration and composition in the maintenance of hepatocyte polarity and functionBiomaterials19961733733858745335
  • WangYKYuXCohenDMBone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tensionStem Cells Dev20122171176118621967638
  • LaiCFChengSLAlphavbeta integrins play an essential role in BMP-2 induction of osteoblast differentiationJ Bone Miner Res200520233034015647827
  • DuJChenXLiangXIntegrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticityProc Natl Acad Sci U S A2011108239466947121593411
  • PantovicAKrsticAJanjetovicKCoordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cellsBone201352152453123111315
  • BjornstiMAHoughtonPJThe TOR pathway: a target for cancer therapyNat Rev Cancer20044533534815122205
  • YehLCMaXFordJJAdamoMLLeeJCRapamycin inhibits BMP-7-induced osteogenic and lipogenic marker expressions in fetal rat calvarial cellsJ Cell Biochem201311481760177123444145
  • LeeDYLiYSChangSFOscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathwayJ Biol Chem20102851304219889638
  • OgawaTTokudaMTomizawaKOsteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cellsBiochem Biophys Res Commun199824912262309705862
  • SinghaUKJiangYYuSRapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cellsJ Cell Biochem2008103243444617516572
  • VinalsFLopez-RoviraTRosaJLVenturaFInhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2FEBS Lett20025101–29910411755539