Novel oral contraceptive for heavy menstrual bleeding: estradiol valerate and dienogest

References

• CoteIJacobsPCummingDCUse of health services associated with increased menstrual loss in the United StatesAm J Obstet Gynecol200318834334812592237
   PubMed Web of Science ®Google Scholar
• SpencerCPWhiteheadMIEndometrial assessment re-visitedBr J Obstet Gynaecol199910662363210428515
   PubMedGoogle Scholar
• ThompsonBLPonce de LeonRKiekeBVelebilPWingoPATrends in hospitalizations for abnormal uterine bleeding in the United States: 1980–1992J Women’s Health1997673819065376
   PubMed Web of Science ®Google Scholar
• ShapleyMJordanKCroftPRIncreased vaginal bleeding and psychological distress: a longitudinal study of their relationship in the communityBJOG200311054855412798470
   PubMed Web of Science ®Google Scholar
• CoteIJacobsPCummingDWork loss associated with increased menstrual loss in the United StatesObstet Gynecol200210068368712383534
   PubMed Web of Science ®Google Scholar
• MunroMGCritchleyHOBroderMSFraserISFIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive ageInt J Gynaecol Obstet201111331321345435
   PubMed Web of Science ®Google Scholar
• LiuZDoanQVBlumenthalPDuboisRWA systematic review evaluating health-related quality of life, work impairment, and healthcare costs and utilization in abnormal uterine bleedingValue Health20071018319417532811
   PubMed Web of Science ®Google Scholar
• American College of Obstetricians and GynecologistsPractice bulletin no 128: diagnosis of abnormal uterine bleeding in reproductive-aged womenObstet Gynecol201212019720622914421
   PubMedGoogle Scholar
• FraserISCritchleyHOMunroHGBroderMA process designed to lead to international agreement on terminologies and definitions to be used to describe abnormalities of menstrual bleedingFertil Steril20078746647617362717
   PubMed Web of Science ®Google Scholar
• JamesAHMore than menorrhagia: a review of the obstetric and gynaecological manifestations of bleeding disordersHaemophilia20051129530716011580
   PubMed Web of Science ®Google Scholar
• ShankarMLeeCASabinCAEconomidesDLKadirRAvon Willebrand disease in women with menorrhagia: a systematic reviewBJOG200473474015198765
   PubMed Web of Science ®Google Scholar
• DilleyADrewsCMillerCvon Willebrand disease and other inherited bleeding disorders in women with diagnosed menorrhagiaObstet Gynecol20019763063611275041
   PubMed Web of Science ®Google Scholar
• KadirRAEconomidesDLSabinCAOwensDLeeCAFrequency of inherited bleeding disorders in women with menorrhagiaLancet19983514854899482440
   PubMed Web of Science ®Google Scholar
• Natazia (estradiol valerate/dienogest) [package insert]Wayne, NJBayer HealthCare Pharmaceuticals2012 Available from: http://labeling.bayerhealthcare.com/html/products/pi/natazia_pi.pdfAccessed April 9, 2013
   Google Scholar
• FruzzettiFBitzerJReview of clinical experience with estradiol in combined oral contraceptivesContraception20108181520004267
   PubMed Web of Science ®Google Scholar
• KileyJWShulmanLPEstradiol valerate and dienogest: a new approach to oral contraceptionInt J Womens Health2011328128621892339
   PubMedGoogle Scholar
• PalaciosSWildtLParkeSMachlittARömerTBitzerJEfficacy and safety of a novel oral contraceptive based on oestradiol (oestradiol valerate/dienogest): a Phase III trialEur J Obstet Gynecol Reprod Biol2010149576219969409
   PubMed Web of Science ®Google Scholar
• ZeunSLuMUddinAPharmacokinetics of an oral contraceptive containing oestradiol valerate and dienogestEur J Contracept Reprod Health Care20091422123219565420
   PubMed Web of Science ®Google Scholar
• RuanXSeegerHMueckAOThe pharmacology of dienogestMaturitas20127133734422364708
   PubMed Web of Science ®Google Scholar
• SasagawaSShimizuYKamiHDienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profileSteroids20087322223118061638
   PubMed Web of Science ®Google Scholar
• JensenJTParkeSMellingerUMachlittAFraserISEffective treatment of heavy menstrual bleeding with estradiol valerate and dienogest: a randomized controlled trialObstet Gynecol201111777778721422847
   PubMed Web of Science ®Google Scholar
• FraserISRomerTParkeSEffective treatment of heavy and/or prolonged menstrual bleeding with an oral contraceptive containing estradiol valerate and dienogest: a randomized, double-blind Phase III trialHum Reprod2011262698270821784734
   PubMed Web of Science ®Google Scholar
• FraserISParkeSMellingerUMachlittASerraniMJensenJEffective treatment of heavy and/or prolonged menstrual bleeding without organic cause: pooled analysis of two multinational, randomized, double-blind, placebo-controlled trials of oestradiol valerate and dienogestEur J Contracept Reprod Health Care20111625826921774563
   PubMed Web of Science ®Google Scholar
• FraserISJensenJSchaefersMMellingerUParkeSSerraniMNormalization of blood loss in women with heavy menstrual bleeding treated with an oral contraceptive containing estradiol valerate/dienogestContraception2012869610122240178
   PubMed Web of Science ®Google Scholar
• AhrendtHJMakalovaDParkeSMellingerUMansourDBleeding pattern and cycle control with an estradiol-based oral contraceptive: a seven cycle, randomized, comparative trial of estradiol valerate/dienogest and ethinyl estradiol/levonorgestrelContraception20098043644419835717
   PubMed Web of Science ®Google Scholar
• ParkeSNahumGMellingerUJungeWMetabolic effect of a new four-phasic oral contraceptive containing estradiol valerate and dienogestObstet Gynecol2008111Suppl 4S12S13
   Web of Science ®Google Scholar
• HoySMScottLJEstradiol valerate/dienogest: in oral contraceptionDrugs2009691635164619678714
   PubMed Web of Science ®Google Scholar
• ParkeSJungeWMellingerUDujkersIKlippingCComparative effects of a four-phasic regimen of estradiol valerate/dienogest versus ethinyl estradiol/levonorgestrel on haemostatic parametersHum Reprod200823Suppl 1i78i79
   Google Scholar
• International Active Surveillance Study-Safety of Contraceptives: Role of Estrogens (INAS-SCORE) Available from: from: http://clinicaltrials.gov/Accessed January 31, 2013
   Google Scholar
• NelsonASampson-LandersCParkeSJensenJTEfficacy of estradiol valerate/dienogest OC: results of 3 large studies in North America and EuropeAbstract presented at the 57th Annual Clinical Meeting of the American Congress of Obstetricians and GynecologistsMay 2–6, 2009Chicago, IL
   Google Scholar
• BorgeltLMMartellCWEstradiol valerate/dienogest: a novel combined oral contraceptiveClin Ther201234375522169052
   PubMed Web of Science ®Google Scholar
• American College of Obstetricians and GynecologistsACOG practice bulletin: management of anovulatory bleedingInt J Gynaecol Obstet20017226327111296797
   PubMed Web of Science ®Google Scholar
• [No authors listed]ACOG practice bulletin: Noncontraceptive uses of hormonal contraceptivesObstet Gynecol2010110206218
   Google Scholar
• ShaabanMMZakherahMSEl-NasharSALevonorgestrel-releasing intrauterine system compared to low dose combined oral contraceptive pills for idiopathic menorrhagia: a randomized clinical trialContraception201183485421134503
   PubMed Web of Science ®Google Scholar
• GuptaJKaiJMiddletonLPattisonHGrayRDanielsJLevonorgestrel intrauterine system versus medical therapy for menorrhagiaN Engl J Med201336812813723301731
   PubMed Web of Science ®Google Scholar
• LethabyAECookeIReesMProgesterone or progestogen-releasing intrauterine systems for heavy menstrual bleedingCochrane Database Syst Rev200519CD00212616235297
   PubMed Web of Science ®Google Scholar
• FraserISMcCarronGRandomized trial of 2 hormonal and 2 prostaglandin-inhibiting agents in women with a complaint of menorrhagiaAust N Z J Obstet Gynaecol19913166701872778
   PubMed Web of Science ®Google Scholar
• MäkäräinenLYlikorkalaOPrimary and myoma-associated menorrhagia: role of prostaglandins and effects of ibuprofenBr J Obstet Gynaecol1986939749783533137
   PubMedGoogle Scholar
• HallPMaclachlanNThornNNuddMWTaylorCGGarriochDBControl of menorrhagia by the cyclo-oxygenase inhibitors naproxen sodium and mefenamic acidBr J Obstet Gynaecol1987945545583304401
   PubMedGoogle Scholar
• LethabyAAugoodCDuckittKNonsteroidal anti-inflammatory drugs for heavy menstrual bleedingCochrane Database Syst Rev20021CD00040011869575
   PubMedGoogle Scholar
• CarrBRMarshburnPBWeatherallPTAn evaluation of the effect of gonadotropin-releasing hormone analogs and medroxyprogesterone acetate on uterine leiomyomata volume by magnetic resonance imaging: a prospective, randomized, double blind, placebo-controlled, crossover trialJ Clin Endocrinol Metab199376121712238496313
   PubMed Web of Science ®Google Scholar
• MarshallLMSpiegelmanDGoldmanMBA prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomataFertil Steril1998704324399757871
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and PreventionUS medical eligibility criteria for contraceptive use, 2010MMWR Available from: http://www.cdc.gov/mmwr/pdf/rr/rr59e0528.pdfAccessed April 9, 2013
   Google Scholar
• World Health OrganizationMedical Eligibility Criteria for Contraceptive Use4th edGeneva, SwitzerlandWorld Health Organization2009 Available from: http://www.who.int/reproductivehealth/publications/family_planning/9789241563888/en/index.htmlAccessed April 9, 2013
   Google Scholar