References
- World Health Organization (WHO). Ageing and health. 2018 Available from: https://www.who.int/news-room/fact-sheets/detail/ageing-and-health. Accessed 315, 2020.
- World Health Organization (WHO). Mental health of older adults. 2017 Available from: https://www.who.int/news-room/fact-sheets/detail/mental-health-of-older-adults. Accessed 315, 2020.
- Alzheimer’s Association. Alzheimer’s disease facts and figures. 2020 Available from: https://www.alz.org/media/Documents/alzheimers-facts-and-figures.pdf. Accessed 410, 2020.
- Steinberg M, Shao H, Zandi P, et al. Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the cache county study. Int J Geriatr Psychiatry. 2008;23(2):170–177. doi:10.1002/gps.185817607801
- Appleby BS, Roy P, Valenti A, Lee HB. Diagnosis and treatment of depression in Alzheimer’s disease: impact on mood and cognition. Panminerva Med. 2007;49(3):139–149.17912149
- Netuveli G, Blane D. Quality of life in older ages. Br Med Bull. 2008;85:113–126. doi:10.1093/bmb/ldn00318281376
- Kales HC, Chen P, Blow FC, Welsh DE, Mellow AM. Rates of clinical depression diagnosis, functional impairment, and nursing home placement in coexisting dementia and depression. Am J Geriatr Psychiatry. 2005;13(6):441–449. doi:10.1097/00019442-200506000-0000215956263
- Buettner LL, Fitzsimmons S, Dudley WN. Impact of underlying depression on treatment of neuropsychiatric symptoms in older adults with dementia. Res Gerontol Nurs. 2010;3(3):221–232. doi:10.3928/19404921-20100601-0220635806
- Buhr GT, White HK. Difficult behaviors in long-term care patients with dementia. J Am Med Dir Assoc. 2006;7(3):180–192. doi:10.1016/j.jamda.2005.12.00316503312
- Herrmann N, Lanctot KL. Pharmacologic management of neuropsychiatric symptoms of alzheimer disease. Can J Psychiatry. 2007;52(10):630–646. doi:10.1177/07067437070520100418020111
- Sink KM, Holden KF, Yaffe K. Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. JAMA. 2005;293(5):596–608. doi:10.1001/jama.293.5.59615687315
- Lyketsos CG, DelCampo L, Steinberg M, et al. Treating depression in Alzheimer disease: efficacy and safety of sertraline therapy, and the benefits of depression reduction: the DIADS. Arch Gen Psychiatry. 2003;60(7):737–746. doi:10.1001/archpsyc.60.7.73712860778
- Caballero J, Hitchcock M, Beversdorf D, Scharre D, Nahata M. Long-term effects of antidepressants on cognition in patients with Alzheimer’s disease. J Clin Pharm Ther. 2006;31(6):593–598. doi:10.1111/j.1365-2710.2006.00778.x17176364
- Starkstein SE, Mizrahi R. Depression in Alzheimer’s disease. Expert Rev Neurother. 2006;6(6):887–895. doi:10.1586/14737175.6.6.88716784411
- Cooper JP. Buspirone for anxiety and agitation in dementia. J Psychiatry Neurosci. 2003;28(6):469.14631458
- Rosenberg PB, Martin BK, Frangakis C, et al. Sertraline for the treatment of depression in Alzheimer disease. Am J Geriatr Psychiatry. 2010;18(2):136–145. doi:10.1097/JGP.0b013e3181c796eb20087081
- Weintraub D, Rosenberg PB, Drye LT, et al. Sertraline for the treatment of depression in Alzheimer disease: week-24 outcomes. Am J Geriatr Psychiatry. 2010;18(4):332–340. doi:10.1097/JGP.0b013e3181cc033320220589
- Dudas R, Malouf R, McCleery J, Dening T. Antidepressants for treating depression in dementia. Cochrane Database Syst Rev. 2018;8:CD003944.30168578
- Banerjee S, Hellier J, Romeo R, et al. Study of the use of antidepressants for depression in dementia: the HTA-SADD trial–a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine. Health Technol Assess. 2013;17(7):1–166. doi:10.3310/hta17070
- Orgeta V, Tabet N, Nilforooshan R, Howard R. Efficacy of antidepressants for depression in Alzheimer’s disease: systematic review and meta-analysis. J Alzheimers Dis. 2017;58(3):725–733. doi:10.3233/JAD-16124728505970
- Su JA, Chang CC, Wang HM, Chen KJ, Yang YH, Lin CY. Antidepressant treatment and mortality risk in patients with dementia and depression: a nationwide population cohort study in Taiwan. Ther Adv Chronic Dis. 2019;10:2040622319853719. doi:10.1177/204062231985371931210918
- Bhattacharjee S, Lee JK, Patanwala AE, et al. Extent and predictors of potentially inappropriate antidepressant use among older adults with dementia and major depressive disorder. Am J Geriatr Psychiatry. 2019;27(8):794–805. doi:10.1016/j.jagp.2019.02.00230926273
- Assurance NCfQ. HEDIS Technical Specifications. Vol. 2 Washington, DC: National Committee for Quality Assurance; 2016:160–163.
- By the American Geriatrics Society Beers Criteria Update Expert P. American Geriatrics Society 2015 updated beers criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2015;63(11):2227–2246. doi:10.1111/jgs.1370226446832
- O’Mahony D, O’Sullivan D, Byrne S, O’Connor MN, Ryan C, Gallagher P. STOPP/START criteria for potentially inappropriate prescribing in older people: version 2. Age Ageing. 2015;44(2):213–218. doi:10.1093/ageing/afu14525324330
- Centers for Medicare and Medicaid Services. Chronic conditions data warehouse. Available from: https://www.ccwdata.org/web/guest/condition-categories. 2016 Accessed 310, 2020.
- Wei W, Sambamoorthi U, Olfson M, Walkup JT, Crystal S. Use of psychotherapy for depression in older adults. Am J Psychiatry. 2005;162(4):711–717. doi:10.1176/appi.ajp.162.4.71115800143
- Crystal S, Sambamoorthi U, Walkup JT, Akincigil A. Diagnosis and treatment of depression in the elderly medicare population: predictors, disparities, and trends. J Am Geriatr Soc. 2003;51(12):1718–1728. doi:10.1046/j.1532-5415.2003.51555.x14687349
- Sambamoorthi U, Olfson M, Walkup JT, Crystal S. Diffusion of new generation antidepressant treatment among elderly diagnosed with depression. Med Care. 2003;41(1):180–194. doi:10.1097/00005650-200301000-0001912544554
- Sambamoorthi U, Shen C, Findley P, Frayne S, Banerjea R. Depression treatment patterns among women veterans with cardiovascular conditions or diabetes. World Psychiatry. 2010;9(3):177–182. doi:10.1002/j.2051-5545.2010.tb00306.x20975865
- Perez A, Anzaldua M, McCormick J, Fisher-Hoch S. High frequency of chronic end-stage liver disease and hepatocellular carcinoma in a Hispanic population. J Gastroenterol Hepatol. 2004;19(3):289–295. doi:10.1111/j.1440-1746.2003.03277.x14748876
- Quan H, Sundararajan V, Halfon P, et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care. 2005;43(11):1130–1139. doi:10.1097/01.mlr.0000182534.19832.8316224307
- Zhu CW, Cosentino S, Ornstein KA, Gu Y, Andrews H, Stern Y. Interactive effects of dementia severity and comorbidities on medicare expenditures. J Alzheimers Dis. 2017;57(1):305–315. doi:10.3233/JAD-16107728222520
- Bhattacharjee S, Metzger A, Tworek C, Wei W, Pan X, Sambamoorthi U. Parkinson’s disease and home healthcare use and expenditures among elderly medicare beneficiaries. Parkinsons Dis. 2015;2015:606810.26090265
- Noyes K, Liu H, Holloway R, Dick AW. Accuracy of medicare claims data in identifying parkinsonism cases: comparison with the medicare current beneficiary survey. Mov Disord. 2007;22(4):509–514. doi:10.1002/mds.2129917230477
- Bhattacharya R, Shen C, Wachholtz AB, Dwibedi N, Sambamoorthi U. Depression treatment decreases healthcare expenditures among working age patients with comorbid conditions and type 2 diabetes mellitus along with newly-diagnosed depression. BMC Psychiatry. 2016;16:247. doi:10.1186/s12888-016-0964-927431801
- Harpaz-Rotem I, Libby D, Rosenheck RA. Psychotherapy use in a privately insured population of patients diagnosed with a mental disorder. Soc Psychiatry Psychiatr Epidemiol. 2012;47(11):1837–1844. doi:10.1007/s00127-012-0486-922349151
- Bhattacharjee S, Oh YM, Reiman EM, Burke WJ. Prevalence, patterns, and predictors of depression treatment among community-dwelling elderly individuals with dementia in the United States. Am J Geriatr Psychiatry. 2017;25(7):803–813. doi:10.1016/j.jagp.2017.03.00328392190
- Akincigil A, Olfson M, Siegel M, Zurlo KA, Walkup JT, Crystal S. Racial and ethnic disparities in depression care in community-dwelling elderly in the United States. Am J Public Health. 2012;102(2):319–328. doi:10.2105/AJPH.2011.30034922390446
- Alegria M, Chatterji P, Wells K, et al. Disparity in depression treatment among racial and ethnic minority populations in the United States. Psychiatr Serv. 2008;59(11):1264–1272. doi:10.1176/ps.2008.59.11.126418971402
- Miranda J, Cooper LA. Disparities in care for depression among primary care patients. J Gen Intern Med. 2004;19(2):120–126. doi:10.1111/j.1525-1497.2004.30272.x15009791
- Health UDoHaHSM. Culture, Race, and Ethnicity a Supplement to Mental Health: A Report of the Surgeon General. Rockville, MD: US Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Mental Health Services; 2001:2001.
- Gonzalez HM, Vega WA, Williams DR, Tarraf W, West BT, Neighbors HW. Depression care in the United States: too little for too few. Arch Gen Psychiatry. 2010;67(1):37–46. doi:10.1001/archgenpsychiatry.2009.16820048221
- Cardemil EV, Nelson T, Keefe K. Racial and ethnic disparities in depression treatment. Curr Opin Psychol. 2015;4:37–42. doi:10.1016/j.copsyc.2015.01.021
- Bosworth HB, Voils CI, Potter GG, Steffens DC. The effects of antidepressant medication adherence as well as psychosocial and clinical factors on depression outcome among older adults. Int J Geriatr Psychiatry. 2008;23(2):129–134. doi:10.1002/gps.185217563920
- Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353(5):487–497. doi:10.1056/NEJMra05010016079372
- Cooper LA, Gonzales JJ, Gallo JJ, et al. The acceptability of treatment for depression among African-American, hispanic, and white primary care patients. Med Care. 2003;41(4):479–489. doi:10.1097/01.MLR.0000053228.58042.E412665712
- Burnett-Zeigler I, Kim HM, Chiang C, et al. The association between race and gender, treatment attitudes, and antidepressant treatment adherence. Int J Geriatr Psychiatry. 2014;29(2):169–177. doi:10.1002/gps.398423801324
- Akincigil A, Bowblis JR, Levin C, Walkup JT, Jan S, Crystal S. Adherence to antidepressant treatment among privately insured patients diagnosed with depression. Med Care. 2007;45(4):363–369. doi:10.1097/01.mlr.0000254574.23418.f617496721
- Gaspar FW, Zaidel CS, Dewa CS. Rates and determinants of use of pharmacotherapy and psychotherapy by patients with major depressive disorder. Psychiatr Serv. 2019;70(4):262–270. doi:10.1176/appi.ps.20180027530630402
- Katon W, von Korff M, Lin E, Bush T, Ormel J. Adequacy and duration of antidepressant treatment in primary care. Med Care. 1992;30(1):67–76. doi:10.1097/00005650-199201000-000071729588
- Croghan TW, Melfi CA, Dobrez DG, Kniesner TJ. Effect of mental health specialty care on antidepressant length of therapy. Med Care. 1999;37(4Suppl Lilly):AS20–AS23. doi:10.1097/00005650-199904001-0000410217389
- Pampallona S, Bollini P, Tibaldi G, Kupelnick B, Munizza C. Patient adherence in the treatment of depression. Br J Psychiatry. 2002;180:104–109. doi:10.1192/bjp.180.2.10411823317
- Work Group on Major Depressive Disorder. Practice guideline for the treatment of patients with major depressive disorder: third edition. 2010 Available from: https://psychiatryonline.org/pb/assets/raw/sitewide/practice_guidelines/guidelines/mdd.pdf. Accessed 314, 2020.
- Bull SA, Hu XH, Hunkeler EM, et al. Discontinuation of use and switching of antidepressants: influence of patient-physician communication. JAMA. 2002;288(11):1403–1409. doi:10.1001/jama.288.11.140312234237
- Foley KF, DeSanty KP, Kast RE. Bupropion: pharmacology and therapeutic applications. Expert Rev Neurother. 2006;6(9):1249–1265. doi:10.1586/14737175.6.9.124917009913
- Santarsieri D, Schwartz TL. Antidepressant efficacy and side-effect burden: a quick guide for clinicians. Drugs Context. 2015;4:212290. doi:10.7573/dic.21229026576188
- Quitkin FM, Taylor BP, Kremer C. Does mirtazapine have a more rapid onset than SSRIs? J Clin Psychiatry. 2001;62(5):358–361. doi:10.4088/JCP.v62n050911411818