32
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Serum NPTX2 as a Potential Predictive Biomarker for Postoperative Delirium in Patients with Acute Type A Aortic Dissection

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, , , , & show all
Pages 979-987 | Received 21 Feb 2024, Accepted 06 May 2024, Published online: 08 May 2024

References

  • Hameed I, Cifu AS, Vallabhajosyula P. Management of Thoracic Aortic Dissection. JAMA. 2023;329(9):756–757. doi:10.1001/jama.2023.0265
  • Zhu Y, Lingala B, Baiocchi M, et al. Type A Aortic Dissection-Experience Over 5 Decades: JACC Historical Breakthroughs in Perspective. J Am Coll Cardiol. 2020;76(14):1703–1713. doi:10.1016/j.jacc.2020.07.061
  • Bossone E, Eagle KA. Epidemiology and management of aortic disease: aortic aneurysms and acute aortic syndromes. Nat Rev Cardiol. 2021;18(5):331–348. doi:10.1038/s41569-020-00472-6
  • Song Y, Liu L, Jiang B, Wang Y. Risk factors of cerebral complications after Stanford type A aortic dissection undergoing arch surgery. Asian J Surg. 2022;45(1):456–460. doi:10.1016/j.asjsur.2021.07.071
  • Li T, Li J, Yuan L, et al. Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: the RAGA Randomized Trial. JAMA. 2022;327(1):50–58. doi:10.1001/jama.2021.22647
  • Goldberg TE, Chen C, Wang Y, et al. Association of Delirium With Long-term Cognitive Decline: a Meta-analysis. JAMA Neurol. 2020;77(11):1373–1381. doi:10.1001/jamaneurol.2020.2273
  • Koster S, Hensens AG, van der Palen J. The long-term cognitive and functional outcomes of postoperative delirium after cardiac surgery. Ann Thorac Surg. 2009;87(5):1469–1474. doi:10.1016/j.athoracsur.2009.02.080
  • Cai S, Zhang X, Pan W, et al. Prevalence, Predictors, and Early Outcomes of Post-operative Delirium in Patients With Type A Aortic Dissection During Intensive Care Unit Stay. Front Med Lausanne. 2020;7:572581. doi:10.3389/fmed.2020.572581
  • Liu J, Yang F, Luo S, et al. Incidence, Predictors and Outcomes of Delirium in Complicated Type B Aortic Dissection Patients After Thoracic Endovascular Aortic Repair. Clin Interv Aging. 2021;16:1581–1589. doi:10.2147/cia.S328657
  • Liu Z, Pang X, Zhang X, Cao G, Fang C, Wu S. Incidence and Risk Factors of Delirium in Patients After Type-A Aortic Dissection Surgery. J Cardiothorac Vasc Anesth. 2017;31(6):1996–1999. doi:10.1053/j.jvca.2016.11.011
  • Xiao M-F, Xu D, Craig MT, et al. NPTX2 and cognitive dysfunction in Alzheimer’s Disease. Elife. 2017;6:798. doi:10.7554/eLife.23798
  • Libiger O, Shaw LM, Watson MH, et al. Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer’s disease. Alzheimers Dement. 2021;17(12):1976–1987. doi:10.1002/alz.12353
  • Shao K, Shan S, Ru W, Ma C. Association between serum NPTX2 and cognitive function in patients with vascular dementia. Brain Behav. 2020;10(10):e01779. doi:10.1002/brb3.1779
  • Xiao MF, Roh SE, Zhou J, et al. A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function. Sci Adv. 2021;7(48):eabf6935. doi:10.1126/sciadv.abf6935
  • Inouye SK, Westendorp RG, Saczynski JS. Delirium in elderly people. Lancet. 2014;383(9920):911–922. doi:10.1016/s0140-6736(13)60688-1
  • Maldonado JR. Neuropathogenesis of delirium: review of current etiologic theories and common pathways. Am J Geriatr Psychiatry. 2013;21(12):1190–1222. doi:10.1016/j.jagp.2013.09.005
  • Soldan A, Moghekar A, Walker KA, et al. Resting-State Functional Connectivity Is Associated With Cerebrospinal Fluid Levels of the Synaptic Protein NPTX2 in Non-demented Older Adults. Front Aging Neurosci. 2019;11:132. doi:10.3389/fnagi.2019.00132
  • Segal A, Parkes L, Aquino K, et al. Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders. Nat Neurosci. 2023;26(9):1613–1629. doi:10.1038/s41593-023-01404-6
  • Ham T, Leff A, de Boissezon X, Joffe A, Sharp DJ. Cognitive control and the salience network: an investigation of error processing and effective connectivity. J Neurosci. 2013;33(16):7091–7098. doi:10.1523/jneurosci.4692-12.2013
  • Menon V, Uddin LQ. Saliency, switching, attention and control: a network model of insula function. Brain Struct Funct. 2010;214(5–6):655–667. doi:10.1007/s00429-010-0262-0
  • Shi Q, Mu X, Zhang C, Wang S, Hong L, Chen X. Risk Factors for Postoperative Delirium in Type A Aortic Dissection Patients: a Retrospective Study. Med Sci Monit. 2019;25:3692–3699. doi:10.12659/msm.913774
  • Inouye SK, Charpentier PA. Precipitating factors for delirium in hospitalized elderly persons. Predictive model and interrelationship with baseline vulnerability. JAMA. 1996;275(11):852–857.
  • Nashef SA, Roques F, Sharples LD, et al. EuroSCORE II. Eur J Cardiothorac Surg. 2012;41(4):734–744. doi:10.1093/ejcts/ezs043
  • Greaves D, Psaltis PJ, Davis DHJ, et al. Risk Factors for Delirium and Cognitive Decline Following Coronary Artery Bypass Grafting Surgery: a Systematic Review and Meta-Analysis. J Am Heart Assoc. 2020;9(22):e017275. doi:10.1161/jaha.120.017275
  • Nežić DG, Živković IS, Miličić MD, et al. On-line risk prediction models for acute type A aortic dissection surgery: validation of the German Registry of Acute Aortic Dissection Type A score and the European System for Cardiac Operative Risk Evaluation II. Eur J Cardiothorac Surg. 2022;61(5):1068–1075. doi:10.1093/ejcts/ezab517
  • Luehr M, Merkle-Storms J, Gerfer S, et al. Evaluation of the GERAADA score for prediction of 30-day mortality in patients with acute type A aortic dissection. Eur J Cardiothorac Surg. 2021;59(5):1109–1114. doi:10.1093/ejcts/ezaa455
  • O’Neal JB, Billings F, Liu X, et al. Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass. Can J Anaesth. 2017;64(11):1129–1137. doi:10.1007/s12630-017-0938-5
  • Habeeb-Allah A, Alshraideh JA. Delirium post-cardiac surgery: incidence and associated factors. Nurs Crit Care. 2021;26(3):150–155. doi:10.1111/nicc.12492
  • Salem M, Salib M, Friedrich C, et al. Influence of Age on Postoperative Neurological Outcomes after Surgery of Acute Type A Aortic Dissection. J Clin Med. 2021;10(8):546.
  • Pupovac SS, Hemli JM, Bavaria JE, et al. Moderate Versus Deep Hypothermia in Type A Acute Aortic Dissection Repair: insights from the International Registry of Acute Aortic Dissection. Ann Thorac Surg. 2021;112(6):1893–1899. doi:10.1016/j.athoracsur.2021.01.027
  • Fleck TM, Czerny M, Hutschala D, Koinig H, Wolner E, Grabenwoger M. The incidence of transient neurologic dysfunction after ascending aortic replacement with circulatory arrest. Ann Thorac Surg. 2003;76(4):1198–1202. doi:10.1016/s0003-4975(03)00832-4
  • Marcantonio ER. Delirium in Hospitalized Older Adults. N Engl J Med. 2017;377(15):1456–1466. doi:10.1056/NEJMcp1605501
  • Mulkey MA, Roberson DW, Everhart DE, Hardin SR. Choosing the Right Delirium Assessment Tool. J Neurosci Nursing. 2018;50(6):343–348. doi:10.1097/jnn.0000000000000403
  • Boukrina O, Kowalczyk M, Koush Y, Kong Y, Barrett AM. Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: an fMRI Study. Stroke. 2022;53(3):930–938. doi:10.1161/strokeaha.121.035733
  • Choi SH, Lee H, Chung TS, et al. Neural network functional connectivity during and after an episode of delirium. Am J Psychiatry. 2012;169(5):498–507. doi:10.1176/appi.ajp.2012.11060976
  • Pelkey KA, Barksdale E, Craig MT, et al. Pentraxins coordinate excitatory synapse maturation and circuit integration of parvalbumin interneurons. Neuron. 2015;85(6):1257–1272. doi:10.1016/j.neuron.2015.02.020
  • Galasko D, Xiao M, Xu D, et al. Synaptic biomarkers in CSF aid in diagnosis, correlate with cognition and predict progression in MCI and Alzheimer’s disease. Alzheimers Dement. 2019;5:871–882. doi:10.1016/j.trci.2019.11.002
  • Swanson A, Willette AA. Neuronal Pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer’s disease spectrum. Brain Behav Immun. 2016;58:201–208. doi:10.1016/j.bbi.2016.07.148