63
Views
9
CrossRef citations to date
0
Altmetric
Review

Rilonacept in the management of cryopyrin-associated periodic syndromes (CAPS)

, &
Pages 1-8 | Published online: 19 Jan 2010

References

  • NevenBCryopyrinopathies: update on pathogenesis and treatmentNat Clin Pract Rheumatol20084948148918665151
  • HoffmanHMHereditary immunologic disorders caused by pyrin and cryopyrinCurr Allergy Asthma Rep20077532333017697637
  • PrieurAMA chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome. A specific entity analysed in 30 patientsScand J Rheumatol Suppl19876657683482735
  • HoffmanHMFamilial cold autoinflammatory syndrome: phenotype and genotype of an autosomal dominant periodic feverJ Allergy Clin Immunol2001108461562011590390
  • HoffmanHMMutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndromeNat Genet200129330130511687797
  • HoffmanHMPrevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonistLancet200436494471779178515541451
  • ThorntonBDSuccessful treatment of renal amyloidosis due to familial cold autoinflammatory syndrome using an interleukin 1 receptor antagonistAm J Kidney Dis200749347748117336710
  • HawkinsPNInterleukin-1-receptor antagonist in the Muckle- Wells syndromeN Engl J Med2003348252583258412815153
  • DinarelloCAImmunological and inflammatory functions of the interleukin-1 familyAnnu Rev Immunol20092751955019302047
  • Kogan-SakinIProstate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1Carcinogenesis200930469870519233959
  • MaFYBlockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the ratLab Invest200989447048419188913
  • TsuzakiMIL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cellsJ Orthop Res200321225626412568957
  • AksentijevichIDe novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseasesArthritis Rheum200246123340334812483741
  • ChurchLDPrimer: inflammasomes and interleukin 1beta in inflammatory disordersNat Clin Pract Rheumatol200841344218172447
  • ArosteguiJIClinical and genetic heterogeneity among Spanish patients with recurrent autoinflammatory syndromes associated with the CIAS1/PYPAF1/NALP3 geneArthritis Rheum200450124045405015593220
  • AgannaEAssociation of mutations in the NALP3/CIAS1/ PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosisArthritis Rheum20024692445245212355493
  • MartinonFThe inflammasomes: guardians of the bodyAnnu Rev Immunol20092722926519302040
  • MuruveDAThe inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune responseNature2008452718310310718288107
  • PetrilliVThe inflammasome: a danger sensing complex triggering innate immunityCurr Opin Immunol200719661562217977705
  • ArendWPIL-1, IL-18, and IL-33 families of cytokinesImmunol Rev2008223203818613828
  • RossJBUse of anakinra (Kineret) in the treatment of familial cold autoinflammatory syndrome with a 16-month follow-upJ Cutan Med Surg200812181618258152
  • Goldbach-ManskyRA pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (Interleukin-1 Trap) in patients with familial cold autoinflammatory syndromeArthritis Rheum20085882432244218668591
  • LachmannHJUse of canakinumab in the cryopyrin-associated periodic syndromeN Engl J Med2009360232416242519494217
  • SavicSMcDermottMFInflammation: canakinumab for the cryopyrin-associated periodic syndromesNat Rev Rheumatol200951052953019798026
  • StychBDobrovolnyDFamilial cold auto-inflammatory syndrome (FCAS): characterization of symptomatology and impact on patients’ livesCurr Med Res Opin20082461577158218423104
  • EconomidesANCytokine traps: multi-component, high-affinity blockers of cytokine actionNat Med200391475212483208
  • HoffmanHMRilonacept for the treatment of cryopyrin-associated periodic syndromes (CAPS)Expert Opin Biol Ther20099451953119344287
  • Arcalyst (rilonacept) [prescribing information]Tarrytown, NYRegeneron2008
  • HoffmanHMEfficacy and safety of rilonacept (Interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studiesArthritis Rheum20085882443245218668535
  • RoldanRAnakinra: new therapeutic approach in children with Familial Mediterranean Fever resistant to colchicineJoint Bone Spine200875450450518541452
  • SacreKDramatic improvement following interleukin 1beta blockade in tumor necrosis factor receptor-1-associated syndrome (TRAPS) resistant to anti-TNF-alpha therapyJ Rheumatol200835235735818260167
  • PickersgillLMMandrup-PoulsenTRThe anti-interleukin-1 in type 1 diabetes action trial – background and rationaleDiabetes Metab Res Rev200925432132419405081
  • ApostolakisSIL-1 cytokines in cardiovascular disease: diagnostic, prognostic and therapeutic implicationsCardiovasc Hematol Agents Med Chem20086215015818473780
  • TerkeltaubRThe interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot studyAnn Rheum Dis200968101613161719635719
  • LequerreTInterleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in FranceAnn Rheum Dis200867330230817947302
  • RiderTGJordanKMThe modern management of goutRheumatology (Oxford)2009
  • Rilonacept [IL-1 Trap, Arcalyst; Regeneron Pharmaceuticals] has reduced the incidence of gout flares in a phase II studyInpharma200811655991
  • HainesKAJuvenile idiopathic arthritis: therapies in the 21st centuryBull NYU Hosp Jt Dis200765320521117922671
  • YokotaSTherapeutic efficacy of humanized recombinant antiinterleukin- 6 receptor antibody in children with systemic-onset juvenile idiopathic arthritisArthritis Rheum200552381882515751095
  • PascualVRole of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockadeJ Exp Med200520191479148615851489
  • LovellDJPreliminary evidence for sustained bioactivity of IL-1 Trap (rilonacept), a long acting IL-1 inhibitor, in systemic juvenile idiopathic arthritis (SJIA)Program and abstracts of the American College of Rheumatology (ACR) 71st Annual MeetingNovember 6–11 2007Boston, MassachusettsAbstract 1282
  • LovellDJLong-term safety and efficacy of rilonacept in patients with systemic juvenile idiopathic arthritisProgram and abstracts of the American College of Rheumatology (ACR) Annual MeetingOctober 17–21 2009Philadelphia Presentation 2053
  • FeldmannMAnti-TNF therapy: where have we got to in 2005?J Autoimmun200525Suppl262816260118
  • EleishiHHThree years experience with the prescription of anti-TNF-alpha inhibitors at Dr Soliman Fakeeh hospital in Jeddah, Saudi ArabiaInt J Rheum Dis200912141920374311
  • KapurSBonkMERilonacept (Arcalyst), an interleukin-1 Trap for the treatment of cryopyrin-associated periodic syndromesP T200934313814119561849
  • Registered clinical studies in the United States of America and global locations URL: http://clinicaltrials.gov/ct2/results?term=rilonaceptAccessed October 12, 2009