REFERENCES
- Chu H, Xia J, Yang Z, Gao J. Melanocortin 4 receptor induces hyperalgesia and allodynia after chronic constriction injury by activation of p38 MAPK in DRG. Int J Neurosci. 2012;122:74–81.
- Bertorelli R, Fredduzzi S, Tarozzo G, Campanella M, Grundy R, Beltramo M, Reggiani A. Endogenous and exogenous melanocortin antagonists induce anti-allodynic effects in a model of rat neuropathic pain. Behav Brain Res. 2005;157:55–62.
- Starowicz K, Mousa SA, Obara I, Chocyk A, Przewłocki R, Wedzony K, Machelska H, Przewłocka B. Peripheral antinociceptive effects of MC4 receptor antagonists in a rat model of neuropathic pain — a biochemical and behavioral study. Pharmacol Rep. 2009;61:1086–95.
- Kalange AS, Kokare DM, Singru PS, Upadhya MA, Chopde CT, Subhedar NK. Central administration of selective melanocortin 4 receptor antagonist HS014 prevents morphine tolerance and withdrawal hyperalgesia. Brain Res. 2007;1181:10–20.
- Starowicz K, Obara I, Przewlocki R, Przewlocka B. Inhibition of morphine tolerance by spinal melanocortin receptor blockade. Pain. 2005;117:401–11.
- Chaki S, Okuyama S. Involvement of melanocortin-4 receptor in anxiety and depression. Peptides. 2005;26:1952–64.