Multiple sclerosis: association with the interleukin-1 gene family polymorphisms in the Turkish population

References

• Noseworthy JH, Lucchinetti C, Rodriguez M, Weinshenker BG. Multiple sclerosis. N Engl J Med 2000;343:938–52.
   PubMed Web of Science ®Google Scholar
• Turkboru U, Alp R, Sur H, Gul L. Prevalence of multiple sclerosis door-to-door survey in Maltepe, Istanbul, Turkey. Neuroepidemiology 2006;27:17–21.
   Google Scholar
• Celik Y, Birgili O, Kiyat A, Guldiken B, Ozkan H, Yılmaz H, Saip S, Yandim-Kuscu D, Sütlaş N, Ağaoğlu J, Utku U, Hayran O, Siva A. Prevalence of multiple sclerosis in the metropolitan area of Edirne City, Turkey. Balkan Med J 2011;28:193–6.
   Web of Science ®Google Scholar
• Dyment DA, Sadovnick AD, Ebers GC. Genetics of multiple sclerosis. Hum Mol Genet 1997;6:1693–8.
   PubMed Web of Science ®Google Scholar
• Kenealy SJ, Babron MC, Bradford Y, Schnetz-Boutaud N, Haines JL, Rimmler JB, Schmidt S, Pericak-Vance MA, Barcellos LF, Lincoln RR, Oksenberg JR, Hauser SL, Clanet M, Brassat D, Edan G, Yaouanq J, Semana G, Cournu-Rebeix I, Lyon-Caen O, Fontaine B, American-French Multiple Sclerosis Genetics Group. A second-generation genomic screen for multiple sclerosis. Am J Hum Genet 2004;75:1070–8.
   Google Scholar
• Lundmark F, Duvefelt K, Iacobaeus E, Kockum I, Wallström E, Khademi M, Oturai A, Ryder LP, Saarela J, Harbo HF, Celius EG, Salter H, Olsson T, Hillert J. Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet 2007;39:1108–13.
   PubMed Web of Science ®Google Scholar
• Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ, Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA, Dubois B, Hauser SL, Garcia-Blanco MA, Pericak-Vance MA, Haines JL, Multiple Sclerosis Genetics Group. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet 2007;39:1083–91.
   PubMed Web of Science ®Google Scholar
• Dinarello CA, Wolff SM. The role of interleukin-1 in disease. N Engl J Med 1993;328:106–13.
   PubMed Web of Science ®Google Scholar
• Hirsch EC, Hunot S, Damier P, Faucheux B. Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration?. Ann Neurol 1998;44(Suppl1):S115–20.
   Google Scholar
• Auron PE. The interleukin 1 receptor: ligand interactions and signal transduction. Cytokine & Growth Factor Rev 1998;9:221–37.
   PubMed Web of Science ®Google Scholar
• Huang J, Xie ZK, Lu RB, Xie ZF. Association of interleukin-1 gene polymorphisms with multiple sclerosis: a meta-analysis. Inflamm Res 2013;62:97–106.
   Google Scholar
• Tarlow JK, Blakemore AI, Lennard A, Solari R, Huges HN, Steinkasserer A, Duff GW. Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat. Human Genetics 1993;91: 403–4.
   PubMed Web of Science ®Google Scholar
• McDowell TL, Symons JA, Ploski R, Førre O, Duff GW. A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism. Arthritis Rheum 1994;38:221–8.
   Google Scholar
• Di Giovine FS, Takhsh E, Blakemore AI, Duff GW. Single base polymorphism at −511 in the human interleukin-1 beta gene (IL1 beta). Hum Mol Genet 1992;1:450.
   PubMedGoogle Scholar
• Pociot F, Molvig J, Wogensen L, Worsaae H, Nerup J. A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro. Eur J Clin Invest 1992;22:396–402.
   PubMed Web of Science ®Google Scholar
• Schrijver HM, Crusius JB, Uitdehaag BM, García González MA, Kostense PJ, Polman CH, Peña AS. Association of interleukin-1beta and interleukin-1 receptor antagonist genes with disease severity in MS. Neurology 1999;52: 595–9.
   PubMedGoogle Scholar
• Schrijver HM, Van As J, Crusius JB, Dijkstra CD, Uitdehaag BM. Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1beta and IL-1ra production in multiple sclerosis. Mediators Inflamm 2003;12:89–94.
   PubMed Web of Science ®Google Scholar
• BorzaniI, Tola MR, Caniatti L, Collins A, De Santis G, Luiselli D, Mamolini E, Scapoli C. The interleukin-1 cluster gene region is associated with multiple sclerosis in an Italian Caucasian population. Eur J Neurol 2010;17:930–8.
   Google Scholar
• Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O'Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 2011;69:292–302.
   PubMed Web of Science ®Google Scholar
• Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
   PubMed Web of Science ®Google Scholar
• Arman A, Yılmaz B, Coker A, Inanc N, Direskeneli H. Interleukin-1 receptor antagonist (IL-1RN) and interleukin-1B gene polymorphisms in Turkish patients with rheumatoid arthritis. Clin Exp Rheumatol 2006;24:643–8.
   PubMed Web of Science ®Google Scholar
• Brosnan CF, Cannella B, Battistini L, Raine CS. Cytokine localization in multiple sclerosis lesions: correlation with adhesion molecule expression and reactive nitrogen species. Neurology 1995;45(Suppl 6):S16–21.
   Google Scholar
• Matsuda M, Tsukada N, Miyagi K, Yanagisawa N. Increased interleukin-1 production by peripheral blood mononuclear cells in patients with multiple sclerosis. J Neurol Sci 1991; 102:100–4.
   Google Scholar
• Imamura K, Suzumura A, Hayashi F, Marunouchi T. Cytokine production by peripheral blood monocytes/macrophages in multiple sclerosis patients. Acta Neurol Scand 1993;87:281–5.
   PubMed Web of Science ®Google Scholar
• Cannella B, Raine CS. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 1995;37:424–35.
   PubMed Web of Science ®Google Scholar
• Dinarello CA, Wolff SM. The role of interleukin-1 in disease. N Engl J Med 1993;328:106–13.
   PubMed Web of Science ®Google Scholar
• Dinerallo CA. A clinical perspective of IL-1β as the gatekeeper of inflammation. Eur J Immunol 2011;41:1203–17.
   Google Scholar
• O'Neill LA. The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol Rev 2008;226:10–18.
   PubMed Web of Science ®Google Scholar
• Inoue M, Shinohara ML. NLRP3 inflammasome and MS/EAE. Autoimmune Diseases 2012;2013:1–8.
   Google Scholar
• Furlan R, Martino G, Galbiati F, Poliani PL, Smiroldo S, Bergami A, Desina G, Comi G, Flavell R, Su MS, Adorini L. Caspase-1 regulates the inflammatory process leading to autoimmune demyelination. Journal of Immunology 1999;163:2403–9.
   PubMed Web of Science ®Google Scholar
• Inoue M, Williams KL, Oliver T, Vandenabeele P, Rajan JV, Miao EA, Mari L, Shinohara ML. Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome. Science Signaling 2012;5(225):1–17.
   Google Scholar
• De Jong BA, Huizinga TW, Bollen EL, Uitdehaag BM, Bosma GP, van Buchem MA, Remarque EJ, Burgmans AC, Kalkers NF, Polman CH, Westendorp RG. Production of IL-1Ra and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis. J Neuroimmunol 2002;126(1–2):172–9.
   Google Scholar
• Carrol ED, Payton A, Payne D, Miyajima F, Chaponda M, Mankhambo LA, Banda DL, Molyneux EM, Cox H, Jacobson G, Carr DF, Molyneux ME, Stewart JP, Quinn JP, Hart CA, Ollier WE. The IL1RN promoter rs4251961 correlates with IL-1 receptor antagonist concentrations in human infection and is differentially regulated by GATA-1. J Immunol 2011;186:2329–35.
   PubMed Web of Science ®Google Scholar
• Arend WP. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev 2002;13:323–40.
   PubMed Web of Science ®Google Scholar
• Huang WX, He B, Hillert J. An interleukin 1-receptor-antagonist gene polymorphism is not associated with multiple sclerosis. J Neuroimmunol 1996;67:143–4.
   PubMed Web of Science ®Google Scholar
• Feakes R, Sawcer S, Broadley S, Coraddu F, Roxburgh R, Gray J, Clayton D, Compston A. Interleukin 1 receptor antagonist (IL-1Ra) in multiple sclerosis. J Neuroimmunol 2000;105:96–101.
   Google Scholar
• Kantarci OH, Atkinson EJ, Hebrink DD, McMurray CT, Weinshenker BG. Association of two variants in IL-1beta and IL-1 receptor antagonist genes with multiple sclerosis. J Neuroimmunol 2000;106:220–7.
   Google Scholar
• Mirowska-Guzel D, Gromadzka G, Mach A, Czlonkowski A, Czlonkowska A. Association of IL1A, IL1B, ILRN, IL6, IL10 and TNF-α polymorphisms with risk and clinical course of multiple sclerosis in a Polish population. J Neuroimmunol 2011;236:87–92.
   PubMed Web of Science ®Google Scholar
• Sciacca FL, Ferri C, Vandenbroeck K, Veglia F, Gobbi C, Martinelli F, Franciotta D, Zaffaroni M, Marrosu M, Martino G, Martinelli V, Comi G, Canal N, Grimaldi LM. Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients. Neurology 1999;52: 1896–8.
   PubMed Web of Science ®Google Scholar
• De la Concha EG, Arroyo R, Crusius JB, Campillo JA, Martin C, Varela de Seijas E, Peña AS, Clavería LE, Fernandez-Arquero M. Combined effect of HLA-DRB1*1501 and interleukin-1 receptor antagonist gene allele 2 in susceptibility to relapsing/remitting multiple sclerosis. J Neuroimmunol 1997;80:172–8.
   Google Scholar
• Mann CL, Davies MB, Stevenson VL, Leary SM, Boggild MD, KoKo C, Jones PW, Fryer AA, Strange RC, Thompson AJ, Hawkins CP. Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity. Neuroimmunol 2002;129:197–204.
   PubMedGoogle Scholar
• Luomala M, Lehtimäki T, Elovaara I, Wang X, Ukkonen M, Mattila K, Laippala P, Koivula T, Hurme M. A study of interleukin-1 cluster genes in susceptibility to and severity of multiple sclerosis. J Neurol Sci 2001;185:123–7.
   PubMedGoogle Scholar
• Hurme M, Santtila S. IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes. Eur J Immunol 1998;28:2598–602.
   PubMed Web of Science ®Google Scholar
• Aggelakis K, Zacharaki F, Dardiotis E, Xiromerisiou G, Tsimourtou V, Ralli S, Gkaraveli M, Bourpoulas D, Rodopoulou P, Papadimitriou A, Hadjigeorgiou G. Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms in Greek multiple sclerosis (MS) patients with bout-onset MS. Neurol Sci 2010;31:253–7.
   Google Scholar
• Harding KE, Liang K, Cossburn MD, Ingram G, Hirst CL, Pickersgill TP, Te Water Naude J, Wardle M, Ben-Shlomo Y, Robertson NP, et al. Long-term outcome of paediatric-onset multiple sclerosis: a population-based study. J Neurol Neurosurg Psychiatry 2013;84:141–7.
   PubMed Web of Science ®Google Scholar
• Rovaris M, Confavreux C, Furlan R, Kappos L, Comi G, Filippi M. Secondary progressive multiple sclerosis: current knowledge and future challenges. Lancet Neurol 2006;5(4):343–54.
   PubMed Web of Science ®Google Scholar