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Research Article

Protective effects of alpha-lipoic acid on experimental sciatic nerve crush injury in rats: assessed with functional, molecular and electromicroscopic analyses

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Pages 935-943 | Received 30 Dec 2013, Accepted 05 Mar 2014, Published online: 09 Apr 2014

References

  • Robinson LR. Traumatic injury to peripheral nerves. Muscle Nerve 2000;23(6):863–73.
  • Dahlin LB, Lundborg G. Use of tubes in peripheral nerve repair. Neurosurg Clin N Am 2001;12(2):341–3.
  • Raimondo S, Fornaro M, Tos P, Perspectives in regeneration and tissue engineering of peripheral nerves. Ann Anat 2011;193(4):334–40.
  • Abe N, Cavalli V. Nerve injury signaling. Curr Opin Neurobiol 2008;18(3):276–83.
  • Navarro X, Vivo M, Valero-Cabre A. Neural plasticity after peripheral nerve injury and regeneration. Prog Neurobiol 2007;82(4):163–201.
  • Ellis-Behnke RG, Liang YX, You SW, Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision. Proc Natl Acad Sci USA 2006;103(13):5054–9.
  • Chen CJ, Ou YC, Liao SL, Transplantation of bone marrow stromal cells for peripheral nerve repair. Exp Neurol 2007;204(1):443–53.
  • Eto M, Sumi H, Fujimura H, Pioglitazone promotes peripheral nerve remyelination after crush injury through CD36 upregulation. J Peripher Nerv Syst 2008;13(3):242–8.
  • Emmez H, Yildirim Z, Kale A, Anti-apoptotic and neuroprotective effects of alpha-lipoic acid on spinal cord ischemia-reperfusion injury in rabbits. Acta Neurochir (Wien) 2010;152(9):1591–600; discussion 600–1.
  • Cadirci E, Altunkaynak BZ, Halici Z, Alpha-lipoic acid as a potential target for the treatment of lung injury caused by cecal ligation and puncture-induced sepsis model in rats. Shock 2010;33(5):479–84.
  • Packer L, Tritschler HJ, Wessel K. Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free Radic Biol Med 1997;22(1–2):359–78.
  • Senoglu M, Nacitarhan V, Kurutas EB, Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve. J Brachial Plex Peripher Nerve Inj 2009;4:22–7.
  • Cameron NE, Cotter MA, Horrobin DH, Tritschler HJ. Effects of alpha-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids. Diabetologia 1998;41(4):390–9.
  • Panigrahi M, Sadguna Y, Shivakumar BR, alpha-Lipoic acid protects against reperfusion injury following cerebral ischemia in rats. Brain Res 1996;717(1–2):184–8.
  • Chen WZ, Qiao H, Zhou W, Upgraded nerve growth factor expression induced by low-intensity continuous-wave ultrasound accelerates regeneration of neurotometicly injured sciatic nerve in rats. Ultrasound Med Biol 2010;36(7):1109–17.
  • Dijkstra JR, Meek MF, Robinson PH, Gramsbergen A. Methods to evaluate functional nerve recovery in adult rats: walking track analysis, video analysis and the withdrawal reflex. J Neurosci Methods 2000;96(2):89–96.
  • Albayrak A, Halici Z, Cadirci E, Inflammation and peripheral 5-HT7 receptors: the role of 5-HT7 receptors in carrageenan induced inflammation in rats. Eur J Pharmacol 2013;715(1–3):270–9.
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method. Methods 2001;25(4):402–8.
  • Pan HC, Yang DY, Ou YC, Neuroprotective effect of atorvastatin in an experimental model of nerve crush injury. Neurosurgery 2010;67(2):376–88; discussion 88–9.
  • Mitsui Y, Schmelzer JD, Zollman PJ, Alpha-lipoic acid provides neuroprotection from ischemia-reperfusion injury of peripheral nerve. J Neurol Sci 1999;163(1):11–6.
  • Kaplan KA, Odabasoglu F, Halici Z, Alpha-lipoic acid protects against indomethacin-induced gastric oxidative toxicity by modulating antioxidant system. J Food Sci 2012;77(11):H224–30.
  • Ranieri M, Sciuscio M, Cortese AM, The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life. Int J Immunopathol Pharmacol 2009;22(3 Suppl):45–50.
  • Ranieri M, Sciuscio M, Cortese A, Possible role of alpha-lipoic acid in the treatment of peripheral nerve injuries. J Brachial Plex Peripher Nerve Inj 2010;5:15–9.
  • Tamaddonfard E, Farshid AA, Ahmadian E, Hamidhoseyni A. Crocin enhanced functional recovery after sciatic nerve crush injury in rats. Iran J Basic Med Sci 2013;16(1):83–90.
  • Sandvig A, Berry M, Barrett LB, Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: expression, receptor signaling, and correlation with axon regeneration. Glia 2004;46(3):225–51.
  • Kang YM, Zhang ZH, Johnson RF, Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure. Circ Res 2006;99(7):758–66.
  • Jaggi AS, Singh N. Exploring the potential of telmisartan in chronic constriction injury-induced neuropathic pain in rats. Eur J Pharmacol 2011;667(1–3):215–21.
  • Leung L, Cahill CM. TNF-alpha and neuropathic pain–a review. J Neuroinflamm 2010;7:27.
  • Wu CY, Tang ZH, Jiang L, PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. Mol Cell Biochem 2012;359(1–2):347–58.
  • Wu F, Miao X, Chen J, Down-regulation of GAP-43 by inhibition of caspases-3 in a rat model of neuropathic pain. Int. J Clin Exp Pathol 2012;5(9):948–55.
  • Stefanis L. Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury. Neuroscientist: a review journal bringing neurobiology, neurology and psychiatry 2005;11(1):50–62.
  • Piotrowski P, Wierzbicka K, Smialek M. Neuronal death in the rat hippocampus in experimental diabetes and cerebral ischaemia treated with antioxidants. Folia Neuropathol/ Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2001;39(3): 147–54.

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