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Original Article

Investigation of the effect of telmisartan on experimentally induced peripheral nerve injury in rats

, , , , , & show all
Pages 464-473 | Received 25 Oct 2013, Accepted 20 Jul 2014, Published online: 26 Aug 2014

References

  • Robinson LR. Traumatic injury to peripheral nerves. Muscle Nerve 2000;23(6):863–73.
  • Liuzzi J, Tedeschi B. Peripheral nerve regeneration. Neurosurg Clin N Am 1991;2:31–99.
  • Burnett M, Zager E. Pathophysiology of peripheral nerve injury: a brief review. Neurosurg Focus 2004;16:1–7.
  • Lundborg G. A 25-year perspective of peripheral nerve surgery: evolving neuroscientific concepts and clinical significance. J Hand Surg Am 2000;25:391–414.
  • Sweetman S. Martindale. 35th ed. London: Pharmaceutical Press; 2007:1191–277.
  • Tang H, Pavel J, Saavedra J, Brimijoin S. Type-1 angiotensin receptors are expressed and transported in motor and sensory axons of rat sciatic nerves. Neuropeptides 2009;43:81–92.
  • Gallinat S, Yu M, Dorst A, et al. Sciatic nerve transection evokes lasting up-regulation of angiotensin AT2 and AT1 receptor mRNA in adult rat dorsal root ganglia and sciatic nerves. Mol Brain Res 1998;57:111–22.
  • Kayaalp S. Rasyonel tedavi yönünden tıbbi farmakoloji. 10. Baskı ed. Ankara: Hacettepe-Taş; 2002.
  • Kasaharaa Y, Taguchia A, Unoa H, et al. Telmisartan suppresses cerebral injury in a murine model of transient focal ischemia. Brain Res 2010;1340:70–80.
  • Gaillard V, Casellas D, Seguin-Devaux C, et al. Pioglitazone improves aortic wall elasticity in a rat model of elastocalcinotic arteriosclerosis. Hypertension 2005;46:372–9.
  • Diep Q, El Mabrouk M, Cohn J, et al. Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptorgamma. Circulation 2002;105:2296–302.
  • Beyer A, Baumbach G, Halabi C, et al. Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy and remodeling. Hypertension 2008;51:867–71.
  • Iwanami J, Mogi M, Tsukuda K, et al. Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator activated receptor-gamma activation in diabetic mice. Hypertension 2010;28:1730–7.
  • Benson S, Pershadsingh H, Ho C, et al. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension 2004;43:993–1002.
  • Derosa G, Cicero AF, Bertone G, et al. Comparison of the effects of telmisartan and nifedipine gastrointestinal therapeutic system on blood pressure control, glucose metabolism, and the lipid profile in patients with type 2 diabetes mellitus and mild hypertension: a 12-month, randomized, double-blind study. Clin Ther 2004;26(8):1228–36.
  • Shindo T, Takasaki K, Uchida K, et al. Ameliorative effects of telmisartan on the inflammatory response and impaired spatial memory in a rat model of Alzheimer's disease incorporating additional cerebrovascular disease factors. Biol Pharm Bull 2012;35(12):2141–7.
  • Jaggi AS, Singh N. Exploring the potential of telmisartan in chronic constriction injury-induced neuropathic pain in rats. Eur J Pharmacol 2011;667(1–3):215–21.
  • Halici Z, Bilen H, Albayrak F, et al. Does telmisartan prevent hepatic fibrosis in rats with alloxan-induced diabetes? Eur J Pharmacol 2009;614(1–3):146–52.
  • Bishnoi HK, Mahadevan N, Balakumar P. The combined strategy with PPAR alpha agonism and AT(1) receptor antagonism is not superior relative to their individual treatment approach in preventing the induction of nephropathy in the diabetic rat. Pharmacol Res 2012;66(4):349–56.
  • Goyal S, Arora S, Bhatt TK, et al. Modulation of PPAR-gamma by telmisartan protects the heart against myocardial infarction in experimental diabetes. Chem-Biol Interact 2010;185(3):271–80.
  • Dijkstra JR, Meek MF, Robinson PH, Gramsbergen A. Methods to evaluate functional nerve recovery in adult rats: walking track analysis, video analysis and the withdrawal reflex. J Neurosci Methods 2000;96(2):89–96.
  • Albayrak A, Halici Z, Cadirci E, et al. Inflammation and peripheral 5-HT7 receptors: the role of 5-HT7 receptors in carrageenan induced inflammation in rats. Eur J Pharmacol 2013;715(1–3):270–9.
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method. Methods 2001;25(4):402–8.
  • Rodrigues MC, Rodrigues AA Jr., Glover LE, et al. Peripheral nerve repair with cultured Schwann cells: getting closer to the clinics. Sci World J 2012;2012:413091.
  • Santo Neto H, Teodori RM, Somazz MC, Marques MJ. Axonal regeneration through muscle autografts submitted to local anaesthetic pretreatment. Br J Plast Surg 1998;51(7):555–60.
  • Thanos PK, Okajima S, Terzis JK. Ultrastructure and cellular biology of nerve regeneration. J Reconstruct Microsurg 1998;14(6):423–36.
  • Lundborg G. A 25-year perspective of peripheral nerve surgery: evolving neuroscientific concepts and clinical significance. J Hand Surg 2000;25(3):391–414.
  • Estus S, Zaks WJ, Freeman RS, et al. Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J Cell Biol 1994;127(6 Pt 1):1717–27.
  • Herdegen T, Skene P, Bahr M. The c-Jun transcription factor–bipotential mediator of neuronal death, survival and regeneration. Trends Neurosci 1997;20(5):227–31.
  • Jung KH, Chu K, Lee ST, et al. Blockade of AT1 receptor reduces apoptosis, inflammation, and oxidative stress in normotensive rats with intracerebral hemorrhage. J Pharmacol Exp Ther 2007;322(3):1051–8.
  • Jiang T, Gao L, Shi J, et al. Angiotensin-(1-7) modulates renin-angiotensin system associated with reducing oxidative stress and attenuating neuronal apoptosis in the brain of hypertensive rats. Pharmacol Res 2013;67(1):84–93.
  • Akishita M, Nagai K, Xi H, et al. Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats. Hypertension 2005;45(6):1188–93.
  • Lodha S, Dani D, Mehta R, et al. Angiotensin II-induced mesangial cell apoptosis: role of oxidative stress. Mol Med 2002;8(12):830–40.
  • Wu CY, Tang ZH, Jiang L, et al. PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. Mol Cell Biochem 2012;359(1–2):347–58.
  • Wu F, Miao X, Chen J, et al. Down-regulation of GAP-43 by inhibition of caspases-3 in a rat model of neuropathic pain. Int J Clin Exp Pathol 2012;5(9):948–55.
  • Stefanis L. Caspase-dependent and -independent neuronal death: two distinct pathways to neuronal injury. Neuroscientist 2005;11(1):50–62.
  • Fouad AA, Qureshi HA, Al-Sultan AI, et al. Nephroprotective effect of telmisartan in rats with ischemia/reperfusion renal injury. Pharmacology 2010;85(3):158–67.
  • Culman J, Nguyen-Ngoc M, Glatz T, et al. Treatment of rats with pioglitazone in the reperfusion phase of focal cerebral ischemia: a preclinical stroke trial. Exp Neurol 2012;238(2):243–53.
  • Schiffrin EL, Amiri F, Benkirane K, et al. Peroxisome proliferator-activated receptors: vascular and cardiac effects in hypertension. Hypertension 2003;42(4):664–8.
  • Medhi B, Aggarwal R, Chakrabarti A. Neuroprotective effect of pioglitazone on acute phase changes induced by partial global cerebral ischemia in mice. Indian J Exp Biol 2010;48(8):793–9.
  • Ito T, Yamakawa H, Bregonzio C, et al. Protection against ischemia and improvement of cerebral blood flow in genetically hypertensive rats by chronic pretreatment with an angiotensin II AT1 antagonist. Stroke 2002;33(9):2297–303.
  • Qureshi AI, Suri MF, Ostrow PT, et al. Apoptosis as a form of cell death in intracerebral hemorrhage. Neurosurgery 2003;52(5):1041–7; discussion 7–8.
  • Chen M, Wang J. Initiator caspases in apoptosis signaling pathways. Apoptosis 2002;7(4):313–9.
  • Budihardjo I, Oliver H, Lutter M, et al. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 1999;15:269–90.
  • Cain K, Bratton SB, Cohen GM. The Apaf-1 apoptosome: a large caspase-activating complex. Biochimie 2002;84(2–3):203–14.
  • Petak I, Houghton JA. Shared pathways: death receptors and cytotoxic drugs in cancer therapy. Pathol Oncol Res 2001;7(2):95–106.
  • Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J 1998;17(6):1675–87.
  • Huang DM, Shen YC, Wu C, et al. Investigation of extrinsic and intrinsic apoptosis pathways of new clerodane diterpenoids in human prostate cancer PC-3 cells. Eur J Pharmacol 2004;503(1–3):17–24.
  • Nakamura T, Keep RF, Hua Y, et al. Oxidative DNA injury after experimental intracerebral hemorrhage. Brain Res 2005;1039(1–2):30–6.
  • Muroya M, Chang K, Uchida K, et al. Analysis of cytotoxicity induced by proinflammatory cytokines in the human alveolar epithelial cell line A549. Biosci Trends 2012;6(2):70–80.
  • Kramer C, Sunkomat J, Witte J, et al. Angiotensin II receptor-independent antiinflammatory and antiaggregatory properties of losartan: role of the active metabolite EXP3179. Circulat Res 2002;90(7):770–6.
  • Nagai N, Oike Y, Izumi-Nagai K, et al. Angiotensin II type 1 receptor-mediated inflammation is required for choroidal neovascularization. Arterioscler Thromb Vasc Biol 2006;26(10):2252–9.
  • Kang YM, Zhang ZH, Johnson RF, et al. Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure. Circulat Res 2006;99(7):758–66.
  • Leung L, Cahill CM. TNF-alpha and neuropathic pain–a review. J Neuroinflam. 2010;7:27.
  • Sukumaran V, Watanabe K, Veeraveedu PT, et al. Telmisartan, an angiotensin-II receptor blocker ameliorates cardiac remodeling in rats with dilated cardiomyopathy. Hypertens Res 2010;33(7):695–702.
  • Nakamura T, Fujiwara N, Kawagoe Y, et al. Effects of telmisartan and enalapril on renoprotection in patients with mild to moderate chronic kidney disease. Eur J Clin Invest 2010;40(9):790–6.
  • Haraguchi T, Iwasaki K, Takasaki K, et al. Telmisartan, a partial agonist of peroxisome proliferator-activated receptor gamma, improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia. Brain Res 2010;1353:125–32.
  • Kasahara Y, Taguchi A, Uno H, et al. Telmisartan suppresses cerebral injury in a murine model of transient focal ischemia. Brain Res 2010;1340:70–80.
  • Potter DD, Sobey CG, Tompkins PK, et al. Evidence that macrophages in atherosclerotic lesions contain angiotensin II. Circulation 1998;98(8):800–7.
  • Kitazono T, Padgett RC, Armstrong ML, et al. Evidence that angiotensin-II is present in human monocytes. Circulation 1995;91(4):1129–34.
  • Pastore L, Tessitore A, Martinotti S, et al. Angiotensin II stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo. Circulation 1999;100(15):1646–52.
  • Kakuta H, Sudoh K, Sasamata M, Yamagishi S. Telmisartan has the strongest binding affinity to angiotensin II type 1 receptor: comparison with other angiotensin II type 1 receptor blockers. Int J Clin Pharmacol Res 2005;25(1):41–6.
  • Marshall TG, Lee RE, Marshall FE. Common angiotensin receptor blockers may directly modulate the immune system via VDR, PPAR and CCR2b. Theor Biol Med Model 2006;3:1.
  • Kumtepe Y, Odabasoglu F, Karaca M, et al. Protective effects of telmisartan on ischemia/reperfusion injury of rat ovary: biochemical and histopathologic evaluation. Fertil Steril 2010;93(4):1299–307.

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