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Scandinavian Journal of Gastroenterology Volume 26, 1991 - Issue 7
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Original Article

The Multi-Crossover Model for Classifying Patients as Responders to a Given Treatment

S. Larsen Medstat Centre for Administration, Design and Statistical Analysis in Medical Research, Strømmen; Dept. of Medicine, Gjøvik County Hospital, Gjøvik; Medical Dept., Glaxo Norway A/S, Oslo, Norway; Dept. of Internal Medicine, Ullevål Hospital, University of Oslo, Oslo, Norway
,
P. Farup Medstat Centre for Administration, Design and Statistical Analysis in Medical Research, Strømmen; Dept. of Medicine, Gjøvik County Hospital, Gjøvik; Medical Dept., Glaxo Norway A/S, Oslo, Norway; Dept. of Internal Medicine, Ullevål Hospital, University of Oslo, Oslo, Norway
,
O. Flaten Medstat Centre for Administration, Design and Statistical Analysis in Medical Research, Strømmen; Dept. of Medicine, Gjøvik County Hospital, Gjøvik; Medical Dept., Glaxo Norway A/S, Oslo, Norway; Dept. of Internal Medicine, Ullevål Hospital, University of Oslo, Oslo, Norway
&
M. Osnes Medstat Centre for Administration, Design and Statistical Analysis in Medical Research, Strømmen; Dept. of Medicine, Gjøvik County Hospital, Gjøvik; Medical Dept., Glaxo Norway A/S, Oslo, Norway; Dept. of Internal Medicine, Ullevål Hospital, University of Oslo, Oslo, Norway
Pages 763-770 | Received 02 Nov 1990, Accepted 07 Mar 1991, Published online: 08 Jul 2009

References

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  • Sandvik L. Single case studies from a statistician's point of view. Scand J Gastroenterol 1988; 23(suppl 147)38–39
  • Øvergaard T, Høyeraal H M, Pale J A, Larsen S. A three years retrospective study of synovectomies in children. Clin Orthop 1990; 259: 76–82
  • Johannessen T, Fjøsne U, Kleveland P M, et al. Cimetidine responders in non-ulcer-dyspepsia. Scand J Gastroenterol 1988; 23: 327–336
  • Johannessen T, Fosstvedt D, Petersen H. Experience with a multi crossover model in dyspepsia. Scand J Gastroenterol 1988; 23(suppl 147)33–39
  • Kleveland P M, Johannessen T, Kristensen P, et al. Effect of pancreatic enzymes in non-ulcer dyspepsia. A pilot study. Scand J Gastroenterol 1990; 25: 298–301
  • Dickstein K, Knutsen H. A double-blind multiple cross-over trial evaluating a transdermal nitroglycerine system versus placebo. Eur Heart J 1985; 6: 50–56
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  • Larsen S, Telstad W, Sørensen Ø, et al. Carbamazepine therapy in restless legs. Discrimination between responder and non-responder. Acta Med Scand 1985; 218: 223–227
  • Hoff G, Larsen S. Epidemiology of polyps in the rectum and sigmoid colon. Discriminant analysis for identification of individuals at risk of developing colorectal neoplasia. Scand J Gastroenterol 1986; 21: 848–852
  • Lærum E, Larsen S. It is possible to characterize recurrent urinary stone formers. Who benefits from thiazide prophylaxis. Acta Med Scand 1987; 221: 103–108
  • Farup P, Larsen S, Ulshagen K, Osnes M. Ranitidine for non-ulcer dyspepsia. The symptomatic effect of ranitidine and classification of responders to treatment. Scand J Gastroenterol 1991; 26, in press
  • Larsen S, Aabakken L, Lillevold P E, et al. Assessing soft data in clinical trials. Pharmaceut Med 1991; 5, in press
  • Kendall M, Stuart A. The advanced theory of statistics. Charles Griffin & Co. Ltd, London 1979; Vol. II
  • Lee E T. Statistical methods for survival data analysis. Lifetime Learning Publications, Belmont 1980
  • Kalbfleisch J D, Prentice R L. The statistical analysis of failure time data. John Wiley & Sons, New York 1980

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