A Decade of Experiences with Radioimmunoassays for Cholecystokinin in the Netherlands

References

• Jansen J BMJ., Lamers C BHW. Low binding of Bolton-Hunter labeled cholecystokinin-33 to carboxyl-terminal CCK-anti-bodies. J Immunol Meth 1982; 51: 223–30
   PubMedGoogle Scholar
• Jansen J BMJ., Lamers C BHW. Radioimmunoassay of chole-cystokinin: production and evaluation of antibodies. J Clin Chem Clin Biochem 1983; 21: 387–94
   PubMedGoogle Scholar
• Jansen J BMJ., Lamers C BHW. Characterization of antisera to cholecystokinin employing different cholecystokinin labels. J Immunol Meth 1984; 71: 1–8
   PubMedGoogle Scholar
• Jansen J BMJ., Lamers C BHW. Immunological evidence of cholecystokinin-39 in porcine brain. Life Sci 1983; 32: 911–3
   PubMedGoogle Scholar
• Jansen J BMJ., Lamers C BHW. Radioimmunoassay of cholecystokinin in human tissue and plasma. Clin Chim Acta 1983; 131: 305–16
   PubMed Web of Science ®Google Scholar
• Jansen J BMJ., Lamers C BHW. Ratio between large and small molecular forms of cholecystokinin in brain and gut of different species. Experientia 1986; 42: 1240–1
   PubMedGoogle Scholar
• Jansen J BMJ., Lamers C BHW. Studies in brain cholecystokinin in different species using sequence specific antisera. Ann NY Acad Sci 1985; 448: 24–32
   PubMedGoogle Scholar
• Jansen J BMJ., Hopman W PM, Lamers C BHW. Plasma cholecystokinin concentrations in patients with pancreatic insufficiency measured by sequence specific radioimmunoassays. Dig DisSci 1984; 29: 1109–17
   PubMed Web of Science ®Google Scholar
• Jansen J BMJ., Lamers C BHW. Effect of bombesin on plasma cholecystokinin in normal subjects and gastrectomized patients measured by sequence specific radioimmunoassays. Surgery 1984; 96: 55–60
   PubMed Web of Science ®Google Scholar
• De Jong A JL, Jansen J BMJ., Hafkenscheid J CM, Lamers C BHW. Role of cholecystokinin in bombesin-stimulated pancreatic enzyme secretion in conscious rats. Pancreas 1990; 5: 194–200
   PubMedGoogle Scholar
• Lamers C BHW., de Jong A JL, Hafkenscheid J CM, Jansen J BMJ. Effect of immunoneutralisation of cholecystokinin on bombesin-stimulated pancreactic enzyme secretion in the rat. Regul Peptides 1989; 26: 305–12
   PubMedGoogle Scholar
• Hopman W PM, Jansen J BMJ., Lamers C BHW. Comparative study of the effect of fat, protein and starch on plasma cholecystokinin in man. Scand J Gastroenterol 1985; 20: 843–7
   PubMed Web of Science ®Google Scholar
• Hopman W PM, Rosenbusch G, Jansen J BMJ., de Jong A JL, Lamers C BHW. Gallbladder contraction: effect of fatty meals and cholecystokinin. Radiology 1985; 157: 37–9
   PubMed Web of Science ®Google Scholar
• Hopman W PM, Jansen J BMJ., Rosenbusch G, Lamers C BHW. Effect of equimolar amounts of long chain trigylycerides and medium chain triglycerides on plasma cholecystokinin and gallbladder contraction. Am J Clin Nutr 1984; 39: 356–9
   PubMed Web of Science ®Google Scholar
• Hopman W PM, de Jong A SL, Rosenbusch G, Jansen J BMJ., Lamers C BHW. Elemental diet stimulates gallbladder contraction and secretion of cholecystokinin and pancreatic polypeptide in man. Dig Dis Sci 1987; 32: 45–9
   PubMedGoogle Scholar
• Douglas B R, Jansen J BMJ., de Jong A JL, Lamers C BHW. Effect of different triglycerides on plasma cholecystokinin levels in the rat. J Nutr 1990; 120: 686–90
   PubMed Web of Science ®Google Scholar
• Douglas B R, Wouterse R A, Jansen J BMJ., de Jong A JL, Lamers C BHW. The influence of different nutrients on plasma cholecystokinin levels in the rat. Experientia 1988; 44: 21–23
   PubMedGoogle Scholar
• Douglas B R, Jansen J BMJ., Tjon aTham R TO, Lamers C BHW. Coffee stimulates cholecystokinin release and gallbladder contraction in man. Am J Clin Nutr 1990; 52: 553–6
   PubMed Web of Science ®Google Scholar
• Layer P, Hotz J, Eysselein V E, Jansen J BMJ., Lamers C BHW., Schmitz-Moormann, Goebell H. Effects of acute hypercalcemia on exocrine pancreatic secretion in the cat. Gastroenterology 1985; 88: 1168–75
   PubMedGoogle Scholar
• Masclee A AM, Jansen J BMJ., Driessen W MM, Geuskens L M, Lamers C BHW. Effect of aging on gallbladder contraction and plasma cholecystokinin secretion in humans. Age 1988; 11: 136–41
   Google Scholar
• Jansen J BMJ., Lamers C BHW. Molecular forms of cholecystokinin in human plasma during infusion of bombesin. Life Sci 1984; 33: 2197–205
   Google Scholar
• Jansen J BMJ., Lamers C BHW. Molecular forms of cholecystokinin in plasma from normal and gastrectomized human subjects following a fat meal. Peptides 1987; 8: 801–5
   PubMed Web of Science ®Google Scholar
• Hopman W PM, Jansen J BMJ., Lamers C BHW. Plasma cholecystokinin response to oral fat in patients with Billroth I and Billroth II gastrectomy. Ann Surg 1984; 199: 276–80
   PubMed Web of Science ®Google Scholar
• Jansen J BMJ., Lamers C BHW. Effect of Insulin-hypoglycaemia on plasma cholecystokinin and plasma pancreatic polypeptide. Scand J Gastroenterol 1983; 18: 219–21, Suppl 82
   Web of Science ®Google Scholar
• Hopman W PM, Jansen J BMJ., Rosenbusch G, Lamers C BHW. Cephalic stimulation of gallbladder contraction in humans. Digestion 1987; 38: 197–203
   PubMed Web of Science ®Google Scholar
• Fried M, Jansen J BMJ., Harpole T, et al. Pancreatobiliary responses to an intragastric amino acid meal. Gastroenterology 1989; 97: 1544–9
   PubMedGoogle Scholar
• Masclee A AM, Jansen J BMJ., Driessen W MM, Geuskens L M, Lamers C BHW. Role of gastric phase in fat induced gallbladder contraction and cholecystokinin release in humans. Eur J Clin Invest 1989; 19: 442–7
   PubMedGoogle Scholar
• de Boer S Y, Masclee A AM, Jebbink M CW, Schipper J, Jansen J BMJ., Lamers C BHW. Effect of intravenous fat on cholecystokinin secretion and gallbladder motility in man. J Enteral Parenteral Nutr 1992; 16: 16–9
   PubMedGoogle Scholar
• Welberg J, Jansen J, Kerstens P, Hessels M, Hafkenscheid J, Lamers C. Intravenous amino-acids stimulate pancreatic enzyme secretion by an atropine-resistant somatostatin-sensitive mechanism. Digestion 1984; 30: 83
   Google Scholar
• Konturek S J, Tasler J, Bilski J, de Jong A JL, Jansen J BMJ., Lamers C BHW. Effect of atropine and somatostatin on cholecystokinin and pancreatic polypeptide secretion in the dog. Intern J Pancreatol 1987; 2: 223–35
   PubMedGoogle Scholar
• Masclee A AM, Jansen J BMJ., Driessen W MM, Geuskens L M, Lamers C BHW. Delayed plasma cholecystokinin and gallbladder responses to intestinal fat in patients with Billroth 1 and II gastrectomy. Surgery 1989; 106: 502–8
   PubMedGoogle Scholar
• de Jong A JL, Klamer M, Jansen J BMJ., Lamers C BHW. Effect of atropine and somatostatin on bombesin stimulated plasma gastrin, cholecystokinin and pancreatic polypeptide in man. Regul Peptides 1987; 17: 285–93
   PubMedGoogle Scholar
• Hopman W PM, Jansen J BMJ., Rosenbusch G, Lamers C BHW. Role of cholecystokinin and the cholinergic system in intestinal stimulation of gallbladder contraction in man. Hepatology 1990; 11: 261–5
   PubMed Web of Science ®Google Scholar
• Masclee A AM, Jansen J BMJ., Driessen W M, Geuskens L M, Lamers C BHW. Effect of truncal vagotomy on cholecystokinin release, gallbladder contraction, and gallbladder sensitivity to cholecystokinin in humans. Gastroenterology 1990; 98: 1338–44
   PubMed Web of Science ®Google Scholar
• Hopman W PM, Jansen J BMJ., Lamers C HW. Plasma cholecystokinin response to a liquid fat meal in vagotimized patients. Ann Surg 1984; 200: 693–7
   PubMed Web of Science ®Google Scholar
• Hopman W PM, Jansen J BMJ., Lamers C BHW. Effect of atropine on plasma cholecystokinin response to intraduodenal fat in man. Digestion 1984; 291: 19–25
   Google Scholar
• Jansen J BMJ., de Jong A JL, Lamers C BHW. The chole-cystokinin-receptor antagonist CR-1409 increases plasma cholecystokinin in rats. Regul Peptides 1989; 24: 209–13
   PubMedGoogle Scholar
• Konturek S J, Tasler J, Bilski J, De Jong A S, Jansen J BMJ., Lamers C BHW. Physiological role and localisation of cholecystokinin release in dogs. Am J Physiol 1986; 250: G391–8
   Google Scholar
• Beglinger C, Kohler E, Stalder G A, Jansen J, Gyr K. What is de maximal effective dose of caerulein in stimulating pancreatic enzyme secretion in man?. Digestion 1986; 35: 125–8
   PubMedGoogle Scholar
• Hopman W PM, Jansen J BMJ., Rosenbusch G, Lamers C BHW. Gallbladder contraction by cholecystokinin bolus; injection or infusion?. Br Med J 1986; 292: 375–6
   PubMed Web of Science ®Google Scholar
• Masclee A AM, Hopman W PM, Corstens F HM, Rosenbusch G, Jansen J BMJ., Lamers C BHW. Simultaneous measurement of gallbladder emptying by cholescintigraphy and ultrasonography during infusion of physiologic doses of cholecystokinin; comparison of two techniques. Radiology 1989; 173: 407–10
   PubMed Web of Science ®Google Scholar
• Beglinger C, Fried M, Whitehouse I, Jansen J B, Lamers C B, Gyr K. Pancreatic enzyme response to a liquid meal and to hormonal stimulation: correlation with plasma secretin and cholecystokinin levels. J Clin Invest 1985; 75: 1471–7
   PubMed Web of Science ®Google Scholar
• Singer M V, Niebel W, Jansen J BMJ., Hoffmeister D, Gotthold S, Goebell H, Lamers C BHW. Pancreatic secretory response to intravenous caerulein and intraduodenal tryptophan studies. Gastroenterology 1989; 96: 925–34
   PubMed Web of Science ®Google Scholar
• Hopman W PM, Kerstens P JSM., Jansen J BMJ., Rosenbusch G, Lamers C BHW. Effect of graded physiologic doses of cholecystokinin on gallbladder contraction measured by ultrasonography; determination of treshold, dose-response relationships and comparison with intraduodenal bilirubin output. Gastroenterology 1985; 83: 1242–7
   Google Scholar
• Kerstens P JSM., Lamers C BHW., Jansen J BMJ., de Jong A JL, Hessels M, Hafkenscheid J CM. Physiological plasma concentrations of cholecystokinin stimulate pancreatic enzyme secretion and gallbladder contraction in man. Life Sci 1985; 36: 565–9
   PubMed Web of Science ®Google Scholar
• Lamers C BHW., Poitras P, Jansen J BMJ., Walsh J H. Relative potencies of cholecytokinin-33 and cholecystokinin-8 measured by radioimmunoassay and bioassay. Scand J Gastroenterol 1983; 18: 191–2, Suppl 82
   Web of Science ®Google Scholar
• Meyer B M, Beglinger C, Jansen J BMJ., et al. Role of cholecystokinin in regulation of gastrointestinal motor functions. Lancet 1989; 2: 12–5
   PubMed Web of Science ®Google Scholar
• Hildebrand P, Beglinger C, Gyr K, et al. Effect of a cholecystokinin receptor antagonist on intestinal phase of pancreatic and biliary responses in man. J Clin Invest 1990; 85: 640–53
   PubMed Web of Science ®Google Scholar
• Jansen J BMJ., Jebbink M CW, Douglas B R, Lamers C BHW. Effect of loxiglumide on bombesin- and meal-stimulated plasma CCK release in man. Eur J Clin Pharmacol 1990; 38: 367–70
   PubMedGoogle Scholar
• Fried M, Erlacher U, Schwizer W, et al. Role of cholecystokinin in the regulation of gastric emptying and pancreatic enzyme secretion in humans. Studies with the cholecystokinin-receptor antagonist loxiglumide. Gastroenterology 1991; 101: 503–11
   PubMed Web of Science ®Google Scholar
• Douglas B R, Jebbink M CW, Tjon A, Tham R, Jansen J BMJ., Lamers C BHW. Effect of loxiglumide (CR-1505) on basal and bombesin stimulated gallbladder volume in man. Eur J Pharmacol 1989; 166: 307–9
   PubMedGoogle Scholar
• Jebbink M CW, Jansen J BMJ., Mooy D M, Rovati L C, Lamers C BHW. Effect of loxiglumide on basal-, gastrin-, and bombesin-stimulated gastric acid secretion and serum gastrin levels in man. Gastroenterology, In press
   Google Scholar
• Jebbink M CW, Jansen J BMJ., Masclee A AM, Lamers C BHW. Lack of effect of the specific CCK-receptor antagonist loxiglumide on CCK-clearance from plasma in man. Br J Clin Pharmacol 1990; 29: 770–3
   PubMedGoogle Scholar
• Jebbink M CW, Jansen J BMJ., Mooy D M, Schouten L M, Lamers C BHW. Effect of exogenous CCK-8s on endogenous cholecystokinin release: evidence against autocrine regulation of cholecystokinin secretion. Peptides, In press
   Google Scholar
• Jebbink M C, Jansen J BMJ., Mooy D M, Rovati L C, Lamers C B. Effect of the specific cholecystokinin-receptor antagonist loxiglumide on bombesin stimulated pancreatic enzyme secretion in man. Regul Pept 1991; 32: 361–8
   PubMedGoogle Scholar
• de Jong A J, Singer M V, Jansen J B, Niebel W, Rovati L C, Lamers C B. Effect of the cholecystokinin-receptor antagonist lorglumide on pancreatic enzyme secretion stimulated by bombesin. food, and caerulein, giving similar plasma cholecystokinin concentrations in the dog. Gut 1991; 32: 215–9
   PubMedGoogle Scholar
• Layer P, Jansen J BMJ., Cherian L, Goebell H. Feedback regulation of human pancreatic secretion: Effects of protease inhibition on duodenal delivery and small intestinal transit of pancreatic enzymes. Gastroenterology 1990; 98: 1338–44
   PubMedGoogle Scholar
• Douglas B R, Woutersen R A, Jansen J BMJ., Rovati L C, Lamers C BHW. Comparison of the effect of lorglumide on pancreatic growth stimulated by camostate in rat and hamster. Life Sci 1990; 46: 281–6
   PubMedGoogle Scholar
• Douglas B R, Woutersen R A, Jansen J BMJ., De Jong A JL, Rovati L C, Lamers C BHW. Modulation by CR-1409 (lorglumide), a cholecystokinin receptor antagonist, of trypsin-inhibitor enhanced growth of azaserine-induced putative preneoplastic lesions in rat pancreas. Cancer Res 1989; 49: 2438–41
   PubMed Web of Science ®Google Scholar
• Masclee A AM, Jansen J BMJ., Driessen W MM, Geuskens L M, Lamers C BHW. Reversible gallbladder dysfunction in pancreatic insufficiency. Gut 1989; 30: 866–72
   PubMed Web of Science ®Google Scholar
• Jansen J BMJ., Lamers C BHW. Cholecystokinin and cystic fibrosis. Lancet 1985; 1: 58
   PubMedGoogle Scholar
• Guicherit O R, Gooszen H G, Jansen J B, van der Burg M P, Lamers C B. Postprandial release of cholecystokinin after duodenum-preserving total pancreatectomy is independent of intraluminal pancreatic protease activity in dogs. Digestion 1990; 47: 226–31
   PubMedGoogle Scholar
• Jansen J BMJ., Jebbink M CW, Mulders H JA, Lamers C BHW. Effect of pancreatic enzyme supplementation on postprandial plasma cholecystokinin secretion in patients with pancreatic insufficiency. Regul Peptides 1989; 25: 333–42
   PubMedGoogle Scholar
• Jebbink M CW, Jansen J BMJ., van der Kley F GH, Mooy D M, Rovati L C, Lamers C BHW. Effect of duodenal juice on bombesin stimulated cholecystokinin release during loxiglumide administration in man. Digestion 1991; 49: 25
   Google Scholar
• Jansen J BMJ., Hopman W PM, Rosenbusch G, Lamers C BHW. Plasma cholecystokinin and gallbladder responses to intraduodenal fat and intravenous cholecystokinin in patients with coeliac disease. Eur J Gastroenterol Hepatol 1992; 4: 349–53
   Google Scholar
• Hopman W PM, Rosenbusch G, Jansen J BMJ. Gallbladder and plasa cholecystokinin responses to intestinally perfused fat and products of fat digestion in patients with untreated celiac disease [abstract]. Gastroenterology 1992, In press
   Google Scholar
• van Haren E H, Hopman W P, Jansen J B, Rosenbusch G, Lamers C B, van Herwaarden C L. Increased plasma cholecystokinin levels and small gall bladders in adult patients with cystic fibrosis. Clin Sci 1991; 81: 85–9
   Google Scholar
• Fried M, Schwizer W, Beglinger C, Keller U, Jansen J B, Lamers C B. Physiological role of cholecystokinin on postprandial insulin secretion and gastric meal emptying in man. Studies with the cholecystokinin receptor antagonist loxiglumide. Diabetologica 1991; 34: 721–6
   PubMedGoogle Scholar
• Fried M, Mayer E A, Jansen J BMJ., et al. Temporal relationships of cholecystokinin release, pancreatobiliary secretion, and gastric emptying of a mixed meal. Gastroenterology 1988; 95: 1344–50
   PubMed Web of Science ®Google Scholar
• Jansen J BMJ., Lamers C BHW. Cholecystokinin, cholecysto-kinin-receptor antagonists and the sphincter of Oddi. Cholecystokinin antagonists in gastroenterology, G Adler, C Beglinger. Springer-Verlag, Berlin 1991; 220–9
   Google Scholar
• Lamers C BHW., Douglas B R, Jansen J BMJ. Cholecystokinin and pancreatic cancer. Scand J Gastroenterol 1988; 23: 103–6, Suppl 154
   PubMed Web of Science ®Google Scholar
• Douglas B R, Woutersen R A, Jansen J BMJ., de Jong A JL, Rovati L C, Lamers C BHW. Modulation by a cholecystokinin receptor antagonist of the effects of cholecystokinin and bombesin on growth of azaserine-induced putative preneoplastic lesions in rat pancreas. Gastroenterology 1989; 96: 462–9
   PubMed Web of Science ®Google Scholar
• Douglas B R, Woutersen R A, Jansen J BMJ., Rovati L C, Lamers C BHW. Study into the role of cholecystokinin in bombesin stimulated pancreatic growth in rats and hamsters. Eur J Pharmacol 1989; 161: 209–14
   PubMedGoogle Scholar
• Meijers M, van Garderen-Hoetmer A, Lamers C BHW., Rovati L C, Jansen J BMJ., Woutersen R A. Effects of the synthetic trypsin inhibitor camostate on the development of BOP-induced pancreatic lesions in hamsters. Cancer Lett 1991; 60: 205–11
   PubMed Web of Science ®Google Scholar
• Lamers C BHW., Douglas B R, Jansen J BMJ., Wouterse R A. Cholecystokinin-receptor antagonists in experimental pancreatic tumor growth. Cholecystokinin antagonists in gastroenterology, G Adler, C Beglinger. Springer-Verlag, Berlin 1991; 203–9
   Google Scholar
• Meijers M, Van Garderen-Hoetmer A, Lamers C BHW., Rovati L C, Jansen J BMJ., Woutersen R A. Effects of bombesin on the development of N-nitrosobis(2-oxopropyl)amine induced pancreatic lesions in hamsters. Cancer Lett 1991; 59: 45–50
   PubMedGoogle Scholar
• Masclee A AM, Jansen J BMJ., Driessen W MM, Geuskens L M, Lamers C BHW. Gallbladder emptying in gallstone patients. Responses to endogenously released cholecystokinin and to caerulein infusion. Dig Dis Sci 1989; 34: 353–9
   PubMedGoogle Scholar
• van Erpecum K J, van Berge Henegouwen G P, Stolk M F, Hop-Man W P, Jansen J BMJ., Lamers C BHW. Effects of ursodeoxycholic acid on gallbladder contraction and cholecystokinin release in gallstone patients and normal subjects. Gastroenterology 1990; 99: 836–42
   PubMedGoogle Scholar