Intensity of stromal changes predicts biochemical recurrence-free survival in prostatic carcinoma

References

• De Wever O, Mareel M. Role of myofibroblasts at the invasion front. Biol Chem 2002;383:55–67.
   PubMed Web of Science ®Google Scholar
• De Wever O, Mareel M. Role of tissue stroma in cancer cell invasion. J Pathol 2003;200:429–47.
   PubMed Web of Science ®Google Scholar
• Kalluri R, Zeisberg M. Fibroblasts in cancer. Nat Rev Cancer 2006;6:392–401.
   PubMed Web of Science ®Google Scholar
• Shimoda M, Mellody KT, Orimo A. Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression. Semin Cell Dev Biol 2010;21:19–25.
   PubMed Web of Science ®Google Scholar
• Ostman A, Augsten M. Cancer-associated fibroblasts and tumor growth -- bystanders turning into key players. Curr Opin Genet Dev 2009;19:67–73.
   PubMed Web of Science ®Google Scholar
• Ronnov-Jessen L, Celis JE, Van Deurs B, Peterson OW. A fibroblast-associated antigen: characterization in fibroblasts and immunoreactivity in smooth muscle differentiated stromal cells. J Histochem Cytochem 1992;40:475–86.
   PubMed Web of Science ®Google Scholar
• Skalli O, Pelte MF, Peclet MC, Gabbiani G, Gugliotta P, Bussolati G, Alpha-smooth muscle actin, a differentiation marker of smooth muscle cells, is present in microfilamentous bundles of pericytes. J Histochem Cytochem 1989;37:315–21.
   PubMed Web of Science ®Google Scholar
• Hast J, Schiffer IB, Neugebauer B, Teichman E, Schreiber W, Brieger J, Angiogenesis and fibroblast proliferation precede formation of recurrent tumors after radiation therapy in nude mice. Anticancer Res 2002;22:677–88.
   PubMed Web of Science ®Google Scholar
• Petersen OW, Nielsen HL, Gudjonsson T, Villadsen R, Rank F, Niebuhr E, Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma. Am J Pathol 2003;162:391–402.
   PubMed Web of Science ®Google Scholar
• Radisky DC, Kenny PA, Bissell MJ. Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT? J Cell Biochem 2007;101:830–9.
   PubMed Web of Science ®Google Scholar
• Ronnov-Jessen L, Petersen OW, Koteliansky VE, Bissell MJ. The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells. J Clin Invest 1995;95:859–73.
   PubMed Web of Science ®Google Scholar
• Chauhan H, Abraham A, Phillips JR, Pringle JH, Walker RA, Jones JL. There is more than one kind of myofibroblast: analysis of CD34 expression in benign, in situ, and invasive breast lesions. J Clin Pathol 2003;56:271–6.
   PubMed Web of Science ®Google Scholar
• Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Res 2007;67:10123–8.
   PubMed Web of Science ®Google Scholar
• Mishra PJ, Mishra PJ, Humeniuk R, Medina DJ, Alexe G, Mesirov JP, Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. Cancer Res 2008;68:4331–9.
   PubMed Web of Science ®Google Scholar
• Cunha GR, Hayward SW, Wang YZ, Ricke WA. Role of the stromal microenvironment in carcinogenesis of the prostate. Int J Cancer 2003;107:1–10.
   PubMed Web of Science ®Google Scholar
• Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DR. Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clin Cancer Res 2002;8:2912–23.
   PubMed Web of Science ®Google Scholar
• Tomas D, Kruslin B. The potential value of (myo)fibroblastic stromal reaction in the diagnosis of prostatic adenocarcinoma. Prostate 2004;61:324–31.
   PubMed Web of Science ®Google Scholar
• Tomas D, Ulamec M, Hudolin T, Bulimbasic S, Belicza M, Kruslin B. Myofibroblastic stromal reaction and expression of tenascin-C and laminin in prostate adenocarcinoma. Prostate Cancer Prostatic Dis 2006;9:414–9.
   PubMed Web of Science ®Google Scholar
• Niu YN, Xia SJ. Stroma--epithelium crosstalk in prostate cancer. Asian J Androl 2009;11:28–35.
   PubMed Web of Science ®Google Scholar
• Augsten M, Hägglöf C, Olsson E, Stolz C, Tsagozis P, Levchenko T, CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth. Proc Natl Acad Sci USA 2009;106:3414–9.
   PubMed Web of Science ®Google Scholar
• Tlsty TD. Stromal cells can contribute oncogenic signals. Semin Cancer Biol 2001;11:97–104.
   PubMed Web of Science ®Google Scholar
• Sobin LH, Wittekind C, . International Union Against Cancer (UICC): TNM classification of malignant tumours. 5th ed. New York: Wiley Liss; 1997.
   Google Scholar
• Ayala G, Tuxhorn JA, Wheeler TM, Frolov A, Scardino PT, Ohori M, Reactive stroma as a predictor of biochemical-free recurrence in prostate cancer. Clin Cancer Res 2003;9:4792–801.
   PubMed Web of Science ®Google Scholar
• Hayward SW, Cunha GR, Dahiya R. Normal development and carcinogenesis of the prostate. A unifying hypothesis. Ann N Y Acad Sci 1996;784:50–62.
   PubMed Web of Science ®Google Scholar
• Wong YC, Wang XH, Ling MT. Prostate development and carcinogenesis. Int Rev Cytol 2003;227:65–130.
   PubMedGoogle Scholar
• Cunha GR, Hayward SW, Dahiya R, Foster BA. Smooth muscle--epithelial interactions in normal and neoplastic prostatic development. Acta Anat (Basel) 1996;155:63–72.
   PubMedGoogle Scholar
• Wong YC, Tam NN. Differentiation of stromal smooth muscle as a factor in prostate carcinogenesis. Differentiation 2002;70:633–45.
   PubMed Web of Science ®Google Scholar
• Cunha GR, Ricke W, Thomson A, Marker PC, Risbridger G, Hayward SW, Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development. J Steroid Biochem Mol Biol 2004;92:221–36.
   PubMed Web of Science ®Google Scholar
• Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999;59:5002–11.
   PubMed Web of Science ®Google Scholar
• Yang F, Tuxhorn JA, Ressler SJ, Mcalhany SJ, Dang TD, Rowley DR. Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis. Cancer Res 2005;65:8887–95.
   PubMed Web of Science ®Google Scholar
• Gabbiani G. The myofibroblast in wound healing and fibrocontractive diseases. J Pathol 2003;200:500–3.
   PubMed Web of Science ®Google Scholar
• Yanagisawa N, Li R, Rowley D, Liu H, Kadmon D, Miles BJ, Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy. Hum Pathol 2007;38:1611–20.
   PubMed Web of Science ®Google Scholar