Is plasma symmetric dimethylarginine a suitable marker of renal function in children and adolescents?

References

• Kakimoto Y, Akazawa S. Isolation and identification of N-G,N-G- and N-G,N′-G-dimethyl-arginine, N-epsilon-mono-, di-, and trimethyllysine, and glucosylgalactosyl- and galactosyl-delta-hydroxylysine from human urine. J Biol Chem 1970;245:5751–8.
   PubMed Web of Science ®Google Scholar
• Lee J, Cook J, Yang Z, Mirochnitchenko O, Gunderson S, Felix A, PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine. J Biol Chem 2005;280:3656–64.
   PubMed Web of Science ®Google Scholar
• Richard S, Morel M, Cléroux P. Arginine methylation regulates IL-2 gene expression: a role for protein arginine methyltransferase 5 (PRMT5). Biochem J 2005;388:379–86.
   PubMed Web of Science ®Google Scholar
• Kielstein J, Boger R, Bode-Boger S, Frölich J, Haller H, Ritz E, Marked increase of asymmetric dimethylarginine in patients with incipient primary chronic renal disease. J Am Soc Nephrol 2002;13:170–6.
   PubMed Web of Science ®Google Scholar
• Marescau B, Nagels G, Possemiers I, De Broe M, Becaus I, Billiouw J, Guanidino compounds in serum and urine of nondialyzed patients with chronic renal insufficiency. Metabolism 1997;46:1024–31.
   PubMed Web of Science ®Google Scholar
• Goonasekera C, Rees D, Woolard P, Frend A, Shah V, Dillon M. Nitric oxide synthase inhibitors and hypertension in children and adolescents. J Hypertens 1997;15:901–9.
   PubMed Web of Science ®Google Scholar
• Kielstein J, Salpeter S, Bode-Boger S, Cooke J, Fliser D. Symmetric dimethylarginine (SDMA) as endogenous marker of renal function – a meta-analysis. Nephrol Dial Transplant 2006;21:2446–51.
   PubMed Web of Science ®Google Scholar
• Fliser D, Kronenberg F, Kielstein J, Morath C, Bode-Boger S, Haller H, Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study. J Am Soc Nephrol 2005;16:2456–61.
   PubMed Web of Science ®Google Scholar
• Perrone R, Madias N, Levey A. Serum creatinine as an index of renal function: new insights into old concepts. Clin Chem 1992;38:1933–53.
   PubMed Web of Science ®Google Scholar
• Gowans E, Fraser C. Biological variation of serum and urine creatinine and creatinine clearance: ramifications for interpretation of results and patient care. Ann Clin Biochem 1988;25:259–63.
   PubMed Web of Science ®Google Scholar
• Schwartz G, Brion L, Spitzer A. The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. Pediatr Clin North Am 1987;34:571–90.
   PubMed Web of Science ®Google Scholar
• Dharnidharka VR, Kwon C, Stevens G. Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am J Kidney Dis 2002;40:221–6.
   PubMed Web of Science ®Google Scholar
• Risch L, Herklotz R, Blumberg A, Huber A. Effects of glucocorticoid immunosuppression on serum cystatin C concentrations in renal transplant patients. Clin Chem 2001;47:2055–9.
   PubMed Web of Science ®Google Scholar
• Fricker M, Wiesli P, Brandle M, Schwegler B, Schmid C Impact of thyroid dysfunction on serum cystatin C. Kidney Int 2003;63;1994–7.
   Web of Science ®Google Scholar
• Levey AS, Eckardt KU, Tsukamoto Y, Levin A, Coresh J, Rossert J, Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int 2005;67:2089–100.
   PubMed Web of Science ®Google Scholar
• Harmon WE. Glomerular filtration rate in children with chronic kidney disease. Clin Chem 2009;55:400–1.
   PubMed Web of Science ®Google Scholar
• Narvaez-Sanchez R, Silva M, Salamanca A, Ríos D. Are the techniques for glomerular filtration rate estimation reliable? Rev UDCA 2006;9:115–20.
   Google Scholar
• Fleck C, Janz A, Schweitzer F, Karge E, Schwertfeger M, Stein G. Serum concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in renal failure patients. Kidney Int Suppl 2001;78:S14–18.
   PubMedGoogle Scholar
• Brooks ER, Langman CB, Wang S, Price HE, Hodges AL, Darling L, Methylated arginine derivatives in children and adolescents with chronic kidney disease. Pediatr Nephrol 2009;24:129–34.
   PubMed Web of Science ®Google Scholar
• Billecke SS, D'Alecy LG, Platel R, Whitesall SE, Jamerson KA, Perlman RL, Blood content of asymmetric dimethylarginine: new insights into its dysregulation in renal disease. Nephrol Dial Transplant 2009;24:489–96.
   PubMed Web of Science ®Google Scholar
• Bode-Boger SM, Scalera F, Kielstein JT, Martens-Lobenhoffer J, Breithardt G, Fobker M, Symmetrical dimethylarginine: a new combined parameter for renal function and extent of coronary artery disease. J Am Soc Nephrol 2006;17:1128–34.
   PubMed Web of Science ®Google Scholar
• Bjarnadottir M, Grubb A, Olafsson I. Promoter-mediated, dexamethasone-induced increase in cystatin C production by HeLa cells. Scand J Clin Lab Invest 1995;55:617–23.
   PubMed Web of Science ®Google Scholar
• Risch L, Herklotz R, Blumberg A, Huber AR. Effects of glucocorticoid immunosuppression on serum cystatin C concentrations in renal transplant patients. Clin Chem 2001;47:2055–9.
   PubMed Web of Science ®Google Scholar
• Uchida HA, Nakamura Y, Kaihara M, Norii H, Hanayama Y, Sugiyama H, Steroid pulse therapy impaired endothelial function while increasing plasma high molecule adiponectin concentration in patients with IgA nephropathy. Nephrol Dial Transplant 2006;21:3475–80.
   PubMed Web of Science ®Google Scholar
• Zoccali C, Maas R, Cutrupi S, Pizzini P, Finocchiaro P, Cambareri F, Asymmetric dimethyl-arginine (ADMA) response to inflammation in acute infections. Nephrol Dial Transplant 2007;22:801–6.
   PubMed Web of Science ®Google Scholar
• Rule AD, Bergstralh EJ, Slezak JM, Bergert J, Larson TS. Glomerular filtration rate estimated by cystatin C among different clinical presentations. Kidney Int 2006;69:399–405.
   PubMed Web of Science ®Google Scholar
• Tarnow L, Hovind P, Teerlink T, Stehouwer CD, Parving HH. Elevated plasma asymmetric dimethylarginine as a marker of cardiovascular morbidity in early diabetic nephropathy in type 1 diabetes. Diabetes Care 2004;27:765–9.
   PubMed Web of Science ®Google Scholar
• Dalton RN, Booth C, Mallard B, Rigby E, Ridgen S, Turner C SDMA is an endogenous marker of glomerular filtration rate (abstract). J Am Soc Nephrol 2005;16.
   Google Scholar
• Marcovecchio ML, Dalton RN, Turner C, Prevost AT, Widmer B, Amin R, Symmetric dimethylarginine, an endogenous marker of glomerular filtration rate, and the risk for microalbuminuria in young people with type 1 diabetes. Arch Dis Child 2010;95:119–24.
   PubMed Web of Science ®Google Scholar
• Kielstein JT, Veldink H, Martens-Lobenhoffer J, Haller H, Burg M, Lorenzen JM, SDMA is an early marker of change in GFR after living-related kidney donation. Nephrol Dial Transplant 2010;26:324–8.
   PubMed Web of Science ®Google Scholar
• White C, Akbari A, Hussain N, Dinh L, Filler G, Lepage N, Estimating glomerular filtration rate in kidney transplantation: a comparison between serum creatinine and cystatin C-based methods. J Am Soc Nephrol 2005;16:3763–70.
   PubMed Web of Science ®Google Scholar
• Stevens LA, Coresh J, Schmid CH, Feldman HI, Froissart M, Kusek J, Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD. Am J Kidney Dis 2008;51:395–406.
   PubMed Web of Science ®Google Scholar
• Delanghe JR. How to estimate GFR in children. Nephrol Dial Transplant 2009;24:714–16.
   PubMed Web of Science ®Google Scholar