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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 6
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Research Article

Effects of Guanxinning injection on rat cytochrome P450 isoforms activities in vivo and in vitro

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Pages 481-487 | Received 27 Sep 2014, Accepted 25 Nov 2014, Published online: 12 Dec 2014

References

  • Barnes J. (2003). Pharmacovigilance of herbal medicines: a UK perspective. Drug Saf 26:829–51
  • Beischlag TV, Luis MJ, Hollingshead BD, et al. (2008). The aryl hydrocarbon receptor complex and the control of gene expression. Crit Rev Eukaryot Gene Expr 18:207–50
  • Bjornsson TD, Callaghan JT, Einolf HJ, et al. (2003). The conduct of in vitro and in vivo drug–drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective. Drug Metab Dispos 31:815–32
  • Chen L. (2013). Observation of therapeutic effect of Atorvastatin combined with Guangxinning injection on unstable angina. China Health Care Nutr 2:817–18
  • Cheng CW, Fan W, Ko SG, et al. (2010). Evidence-based management of herb–drug interaction in cancer chemotherapy. Explore 6:324–9
  • Chien CF, Wu YT, Lee WC, et al. (2010). Herb–drug interaction of Andrographis paniculata extract and andrographolide on the pharmacokinetics of theophylline in rats. Chem Biol Interact 184:458–65
  • China Pharmacopoeia Committee. (1998). Chinese medicine drugs preparations ministerial standard Perhexiline injection (WS3-B-3267-3267). Beijing: The Ministry of Health of the People’s Republic of China Press
  • Corcos L, Marc N, Wein S, et al. (1998). Phenobarbital induces cytochrome P4501A2 hnRNA, mRNA and protein in the liver of C57BL/6J wild type and aryl hydrocarbon receptor knock-out mice. FEBS Lett 425:293–7
  • De Smet PA. (2006). Clinical risk management of herb–drug interactions. Br J Clin Pharmacol 63:258–67
  • Donovan JL, DeVane CL, Chavin KD, et al. (2003). Siberian ginseng (Eleutheroccus senticosus) effects on CYP2D1 and CYP3A1/2 activity in normal volunteers. Drug Metab Dispos 31:519–22
  • Dzeletovic N, McGuire J, Daujat M, et al. (1997). Regulation of dioxin receptor function by omeprazole. J Biol Chem 272:12705–13
  • Fuhr U. (2000). Induction of drug metabolizing enzymes: pharmacokinetic and toxicological consequences in humans. Clin Pharmacokinet 38:493–504
  • Gibbson GG, Sheet P. (1994). Introduction to drug metabolism, 2nd ed. London: Blackie Academic and Professional
  • Gonzalez FJ. (2007). The 2006 Bernard B. Brodie award lecture. Cyp2e1. Drug Metab Dispos 35:1–8
  • Han YG, Wang M. (2013). The analysis of curative effect of Perhexiline injection combined with western medicine in the treatment to unstable angina. Modern Chin Med Appl 7:62
  • He DJ. (2013). Adverse drug reactions induced by Guanxinning injection: literature analysis of 80 cases. Eval Anal Drug-Use Hospitals China 13:944–6
  • Honkakoski P, Sueyoshi T, Negishi M, et al. (2003). Drug-activated nuclear receptors CAR and PXR. Ann Med 35:172–82
  • Izzo AA, Ernst E. (2009). Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs 69:1777–98
  • Jaja C, Burke W, Thummel K, et al. (2008). Cytochrome p450 enzyme polymorphism frequency in indigenous and Native American populations: a systematic review. Community Genet 11:141–9
  • Jin YQ. (2013). Clinical curative effect observation of Guanxinning injection in the treatment of coronary heart disease. Mod Diagn Treat 24:1100–1
  • Ju MH, Li Y. (1998). Effect of cytochrome isoforms in metabolism of foreign substances. Foreign Med Sci Pharm 25:218–23
  • Kennedy DA, Seely D. (2010). Clinically based evidence of drug–herb interactions: a systematic review. Expert Opin Drug Saf 9:79–124
  • Lan K, He JL, Tian Y, et al. (2008). Intra-herb pharmacokinetics interaction between quercetin and isorhamnetin. Acta Pharmacol Sin 29:1376–82
  • Li XB. (2004). Treatment of unstable angina with low molecular heparin calcium combined with Guanxinning injection. Heilongjiang Med J 28:687–8
  • Li Y, Innocentin S, Withers DR, et al. (2011). Exogenous stimuli maintain intraepithelial lymphocytes viaaryl hydrocarbon receptor activation. Cell 147:629–40
  • Li XM, Tu LB. (2010). Clinical summary of new use of Perhexiline injection. J Epidemiol 19:240–1
  • Liu ZJ, Fu DX, Tang G. (2008). FDA drug interactions study guide (draft) version 2006 interpretation. Int J Pharm Res 35:50–8
  • Liu Y, Li X, Yang CJ, et al. (2013). UPLC–MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone in rat plasma and its application to cytochrome P450 activity study in rats. J Chromatogr Sci 51:26–32
  • MacPherson H, Liu B. (2005). The safety of Chinese herbal medicine: a pilot study for a national survey. J Altern Complem Med 11:617–26
  • Moore LB, Maglich JM, McKee DD, et al. (2002). Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors. Mol Endocrinol 16:977–86
  • Otani K, Aoshima T. (2000). Pharmacogenetics of classical and new antipsychotic drugs. Ther Drug Monit 22:118–21
  • Peng XY. (2013). The parallel control study of Perhexiline injection combined with western medicine in the treatment to unstable angina. Pract Internal Med Traditional Chinese Med 27:83–4
  • Ren WH. (2014). Observation of urokinase and Guanxinning injection in the treatment of unstable angina pectoris. Med Innovation China 11:42–4
  • Sandrine V, William B, Robert VH. (2009). Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D1 and 3A. Br J Clin Pharmacol 68:928–35
  • Sharma A, Pilote S, Belanger PM, et al. (2004). A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study. Br J Clin Pharmacol 58:288–97
  • Shimada T, Yamazaki H, Mimura M, et al. (1994). Inter individual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270:414–23
  • Shu Y, Zhou HH. (2000). The progress of cytochrome P450 enzymes in genetic pharmacology. Beijing: Science Press
  • Tao SC, Zhou HT. (2011). Therapeutic effects of Guangxinning on early diabetic nephropathy. J Clin Res 25:1324–5
  • Tirona RG, Kim RB. (2005). Nuclear receptors and drug disposition gene regulation. J Pharm Sci 94:1169–86
  • Tucker GT, Houston JB, Huang SM. (2001). Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential toward a consensus. Pharm Res 18:1071–80
  • Wu W, Li L, Yin KX. (2012). Adverse reaction reports of Guanxinning injection. Anhui Med Pharm J 16:552–3
  • Wu SH, Wu JR, Huang TF, et al. (2014). Clinical study of Guanxinning injection in the treatment of angina pectoris patients. Med Innovation China 11:041–3
  • Xia Y. (2011). 50 cases of treatment by Perhexiline injection combined with western medicine to unstable angina. Shaanxi J Traditional Chin Med 32:1471–2
  • Xiao P, Zhou HH. (2008). Advance in cytochrome P450 1A2. J Cent South Univ 33:456–460
  • Xu Y. (2003). Interactions between cytochrome P450 enzymes and drugs metabolism. Chin Rem Clin 3:142–3
  • Yang JP. (2013). The observation of curative effect of Perhexiline and captopril in treatment to chronic cor pulmonale heart failure. Chinese J Clin Rational Drug Use 6:62–3
  • Yin HM. (2013). The parallel control study of Perhexiline injection combined with western medicine in the treatment to coronary heart disease. Pract Internal Med Traditional Chin Med 27:113–14
  • Zhang Y, Li LF, Qiao FB, et al. (2011). The clinical research of acute aggravating period of Perhexiline injection combined with valsartan in the treatment to chronic cor pulmonale. Hebei Traditional Chin Med 33:1213–14
  • Zhang S, Qin C, Safe SH. (2003). Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context. Environ Health Perspect 111:1877–82
  • Zhang SY, Wei YL, Pan YF. (2010). The observation of curative effect of Perhexiline and mesalazine in treatment to ulcerative colitis. Chin J Clin Rational Drug Use 3:39–40
  • Zhou YH, Zhu LP. (2011). Adverse reaction reports of Guanxinning injection. J Clin Exp Med 10:1127–9

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