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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 8
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Original Article

Hepatic and extrahepatic metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor, of amphetamines in rats: sex and strain differences

Takemi Yoshida Department of Biochemical Toxicology, School of Pharmaceutical Sciences, Showa University, 1–5–8 Hatanodai, Shinagawa-ku, Tokyo, 142, Japan
,
Takiko Oguro Department of Biochemical Toxicology, School of Pharmaceutical Sciences, Showa University, 1–5–8 Hatanodai, Shinagawa-ku, Tokyo, 142, Japan
&
Yukio Kuroiwa Department of Biochemical Toxicology, School of Pharmaceutical Sciences, Showa University, 1–5–8 Hatanodai, Shinagawa-ku, Tokyo, 142, Japan
Pages 957-963 | Received 16 Oct 1986, Published online: 30 Sep 2009

References

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  • Less A. J., Shaw K. M., Kohout L., Stern G. H., Elsworth J. D., Sandler M., Youdim M. B. H. Deprenyl in Parkinson's disease. Lancet 1977; ii: 791–795
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  • Philips S. R. Amphetamine, p-hydroxyamphetamine and β-phenethylamine in mouse brain and urine after (—) — and (+) — deprenyl administration. Journal of Pharmacy and Pharmacology 1981; 33: 739–741
  • Wurtman R. J., Axelrod J. A sensitive and specific assay for the estimation of monoamine oxidase. Biochemical Pharmacology 1963; 12: 1439–1441
  • Yoshida T., Yamada Y., Yamamoto T., Kuroiwa Y. Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: relationship of metabolism to MAO-B inhibitory potency. Xenobiotica 1986; 16: 129–136

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