Clonidine and Naltrexone in the Outpatient Treatment of Heroin Withdrawal

References

• Gold M. S., Redmond D. E., Jr., Kleber H. D. Clonidine in opiate withdrawal. Lancet 1978; 1: 929–930
   PubMed Web of Science ®Google Scholar
• Gold M. S., Redmond D. E., Kleber H. D. Clonidine blocks acute opiate withdrawal symptoms. Lancet 1978; 2: 599–602
   PubMed Web of Science ®Google Scholar
• Uhde T. W., Redmond D. E., Kleber H. D. Clonidine suppresses the opioid abstinence syndrome without clonidine-withdrawal symptoms: A blind inpatient study. Psychiatry Res. 1980; 2: 37–47
   PubMed Web of Science ®Google Scholar
• Washton A. M., et al. Clonidine for opiate detoxification: Outpatient clinical trial. Am. J. Psychiatry 1980; 137: 1121–1122
   PubMed Web of Science ®Google Scholar
• Washton A. M., Resnick R. B. Clonidine vs methadone for opiate detoxification: Double blind outpatient trials. Problems of Drug Dependence: NIDA Research Monograph, L. S. Harris. Department of Health and Human Services publication (ADM). 1980; #34, 89–94; 81–1058
   Google Scholar
• Charney D. S., et al. The clinical use of clonidine in abrupt withdrawal from methadone. Arch. Gen. Psychiatry 1981; 38: 1273–1277
   PubMed Web of Science ®Google Scholar
• Jasinski D. R., Johnson R. E., Kocher T. R. Clonidine in morphine withdrawal: Differential effects on signs and symptoms. Arch. Gen. Psychiatry 1985; 42: 1063–1066
   PubMed Web of Science ®Google Scholar
• Kleber H. D., et al. Clonidine in outpatient detoxification from methadone maintenance. Arch. Gen. Psychiatry 1985; 42: 391–394
   PubMed Web of Science ®Google Scholar
• Wilson B. K., Elms R. R., Thomson C. P. Outpatient vs hospital methadone detoxification: An experimental comparison. Int. J. Addict. 1975; 10(1)13–21
   PubMed Web of Science ®Google Scholar
• Silsby H, Tennant F. S. Short-term, ambulatory detoxification of opiate addicts using methadone. Int. J. Addict. 1974; 9(1)167–170
   PubMed Web of Science ®Google Scholar
• Dorus W., Senay E. C, Showalter C. V. Short term detoxification with methadone. Ann. N. Y. Acad. Sci. 1981; 362: 203–216
   PubMedGoogle Scholar
• Riordan C. E., Kleber H. D. Rapid opiate detoxification with clonidine and naloxone. Lancet 1980; 1: 1079–1080
   PubMed Web of Science ®Google Scholar
• Charney D. S., et al. Clonidine and naltrexone. Arch. Gen. Psychiatry 1982; 39: 1327–1332
   PubMed Web of Science ®Google Scholar
• Martin W. R., et al. Naltrexone, an antagonist for the treatment of heroin dependence. Arch. Gen. Psychiatry 1973; 28: 784–791
   PubMed Web of Science ®Google Scholar
• Hamburg M., Tallman J. F. Chronic morphine administration increases the apparent number of alpha-2 adrenergic receptors in rat brain. Nature 1981; 291: 493–495
   PubMed Web of Science ®Google Scholar
• Anderson R. J., et al. Clonidine overdose: Report of six cases and review of the literature. Ann. Emergency Med. 1981; 10(2)107–112
   PubMed Web of Science ®Google Scholar
• Wang R. I., et al. Rating the presence and severity of opiate dependence. Clin. Pharmacol. Ther. 1974; 16(4)653–658
   PubMed Web of Science ®Google Scholar
• Weisen R. L., et al. The safety and value of naloxone as a therapeutic aid. Drug Alcohol Depend. 1977; 2: 123–130
   PubMed Web of Science ®Google Scholar
• Wang R. I., et al. Initial methadone dose in treating opiate addiction. Int. J. Addict. 1982; 17(2)357–363
   PubMed Web of Science ®Google Scholar
• Hansson L., et al. Blood pressure crisis following withdrawal of clonidine with special reference to arterial and urinary catecholamine levels, and suggestions for acute management. Am. Heart J. 1975; 85: 605
   Web of Science ®Google Scholar
• Stelzer F. P., et al. Late toxicity of clonidine withdrawal. New Engl. J. Med. 1976; 294: 1182
   PubMed Web of Science ®Google Scholar
• Pettinger W. S. Clonidine–A new antihypertensive drug. New Engl. J. Med. 1975; 293: 1179
   PubMed Web of Science ®Google Scholar
• Brahen L. S., et al. Naltrexone and cyclazocine. Arch. Gen. Psychiatry 1977; 34: 1181–1184
   PubMed Web of Science ®Google Scholar
• Callahan E. J., . Comparison of two naltrexone treatment programs: Naltrexone alone versus naltrexone plus behavior therapy. Narcotic Antagonists: Naltrexone, D. Julius, P. Renault, et al. NIDA Research Monograph. 1976; 163–171; 9
   Google Scholar
• Resnick R. B., et al. Psychotherapy and Naltrexone in Opioid Dependence. Paper Presented at Committee on Problems of Drug Dependence. 1980
   Google Scholar
• Kosten T. R., Kleber H. D. Strategies to improve compliance with narcotic antagonists. Am. J. Alcohol Abuse 1984; 10(2)249–266
   PubMed Web of Science ®Google Scholar
• Dorus W. Withdrawal from opioid drugs: A review of techniques and outcomes. Drug Dependent Patients, Treatment and Research, R. J. Craig, S. L. Baker. Thomas, Springfield, Illinois 1982; 7–36
   Google Scholar
• Rotellar J. A. O., et al. Clonidine in thousand-fold overdose. Lancet 1981; 1: 1312
   PubMed Web of Science ®Google Scholar
• Judson B. A., et al. The naloxone test for opiate dependence. Clin. Pharmacol. Ther. 1980; 27: 492–501
   PubMed Web of Science ®Google Scholar
• Redmond D. E., Jr., Krystal J. H. Multiple mechanisms of withdrawal from opioid drugs. Annu. Rev. Neurosci. 1984; 7: 443–478
   PubMed Web of Science ®Google Scholar
• Korf J., Bunney B. S., Aghajanian G. K. Noradrenergic neurons: Morphine inhibition of spontaneous activity. Eur. J. Pharmacol. 1974; 25: 165–169
   PubMed Web of Science ®Google Scholar
• Bird S. J., Kuhar M. J. Iontophoretic application of opiates to the locus coeruleus. Brain Res. 1977; 122: 523–533
   PubMed Web of Science ®Google Scholar
• Llorens C, et al. Hypersensitivity to noradrenaline in cortex after chronic morphine: Relevance to tolerance and dependence. Nature 1978; 274: 603–605
   PubMed Web of Science ®Google Scholar
• Vasquez B. J., Overstreet D. H., Russell R. W. Psychopharmacological evidence for increase in receptor sensitivity following chronic morphine treatment. Psychopharmacologia 1974; 38: 287–302
   PubMedGoogle Scholar
• Gunne L. M. Noradrenaline and adrenaline in the rat brain during acute and chronic morphine administration and during withdrawal. Nature 1959; 184: 1950–1951
   PubMed Web of Science ®Google Scholar
• Crawley J. N., Laverty R. N., Roth R. H. Clonidine reversal of increased norepinephrine metabolite levels during morphine withdrawal. Eur. J. Pharmacol. 1979; 57: 247–255
   PubMed Web of Science ®Google Scholar
• Laverty R., Roth R. H. Clonidine reverses the increased norepinephrine turnover during morphine withdrawal in rats. Brain Res. 1980; 182: 482–485
   PubMed Web of Science ®Google Scholar
• Aghajanian G. K. Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine. Nature 1978; 276: 186–188
   PubMed Web of Science ®Google Scholar
• Cedarbaum J. M., Aghajanian G. K. Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization. Eur. J. Pharmacol. 1977; 44: 375–385
   PubMed Web of Science ®Google Scholar
• Lahti R., Collins R. H. Chronic naloxone results in prolonged increase in opiate binding sites in brain. Eur. J. Pharmacol. 1978; 51: 185–186
   PubMed Web of Science ®Google Scholar
• Schulz R., Wuster M., Herz A. Supersensitivity to opioids following the chronic blockage of endorphin action by naloxone. Nauvn Schmiedebergs Arch. Pharmacol. 1979; 306: 93–96
   PubMed Web of Science ®Google Scholar
• Kosterlitz H. W., Hughes J. Some thoughts on the significance of enkephalin, the endogenous ligand. Life Sci. 1975; 17: 91–96
   PubMed Web of Science ®Google Scholar
• Goldstein A., Cox B. M. Opioid peptides (endorphins in pituitary and brain). Psychoneuroenocrinology 1977; 2: 11–16
   PubMed Web of Science ®Google Scholar
• Kleber H. D., et al. Nontolerance to the opioid antagonism of naltrexone. Biol. Psychiatry 1985; 20: 66–72
   PubMed Web of Science ®Google Scholar
• Sells S. B. Follow-up and treatment outcome. Substance Abuse: Clinical Problems and Perspectives, J. H. Lowinson, P. Ruiz. Williams and Wilkins, Baltimore, Maryland 1981; 783–800
   Google Scholar