Propranolol Versus Diazepam in the Management of the Alcohol Withdrawal Syndrome: Double-Blind Controlled Trial

References

• Kaim S. C, Klett C. J., Rothfeld B. Treatment of the acute alcohol withdrawal state: A comparison of four drugs. Am. J. Psychiatry 1969; 125: 1640–1646
   PubMed Web of Science ®Google Scholar
• Liskow B. I., Goodwin D. W. Pharmacological treatment of alcohol intoxication, withdrawal and dependence: A critical review. J. Stud. Alcohol 1987; 48: 356–370
   PubMed Web of Science ®Google Scholar
• Sellers E. M., Kalant H. Alcohol intoxication and withdrawal. New Engl. J. Med. 1976; 294: 757–762
   PubMed Web of Science ®Google Scholar
• Greenblatt D. J., Shader R. I., Abernethy D. R. Current status of benzodiazepines. New Engl. J. Med. 1983; 309: 410–416
   PubMed Web of Science ®Google Scholar
• Benzer D., Cushman P. Alcohol and benzodiazepines: Withdrawal syndromes. Alcoholism: Clin. Exp. Res. 1980; 4: 243–247
   PubMed Web of Science ®Google Scholar
• Sellers E. M. Alcohol, barbiturate and benzodiazepine withdrawal syndromes: Clinical management. Can. Med. Assoc. J. 1988; 139: 113–118
   PubMed Web of Science ®Google Scholar
• Airaksinen M. M., Peura P. Mechanisms of alcohol withdrawal syndrome. Med. Biol. 1987; 65: 105–112
   PubMedGoogle Scholar
• Borg S., Czarnecka A., Kvande H., Mossberg D., Sedvall G. Clinical conditions and concentrations of MOPEG in the cerebrospinal fluid and urine of male alcoholic patients during withdrawal. Alcoholism: Clin. Exp. Res. 1983; 7: 411–415
   PubMed Web of Science ®Google Scholar
• Hawley R. J., Major L. F., Schulman E. A., Lake C. R. CSF levels of norepinephrine during alcohol withdrawal. Arch. Neurol. 1981; 38: 289–292
   PubMed Web of Science ®Google Scholar
• Hawley R. J., Major L. F., Schulman E. A., Linnoila M. Cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and norephinephine levels in alcohol withdrawal. Arch. Gen. Psychiatry 1985; 42: 1056–1062
   PubMed Web of Science ®Google Scholar
• Tabakoff B., Hoffman P., Moses F. Neurochemical correlates of ethanol withdrawal: Alterations in serotoninergic function. J. Pharm. Pharmacol. 1977; 29: 471–476
   PubMed Web of Science ®Google Scholar
• Linnoila M., Mefford I., Nutt D., Adinoff B. Alcohol withdrawal and noradrenergic function. Ann. Intern. Med. 1987; 107: 875–889
   PubMed Web of Science ®Google Scholar
• Hawley R. J., Major L. F., Schulman E., Trocha P. J., Takenaga J. K., Catravas G. N. Cerebrospinal fluid cyclic nucleotides and GABA do not change in alcohol withdrawal. Life Sci. 1981; 28: 295–299
   PubMed Web of Science ®Google Scholar
• Hemmingsen R., Clemmesen L., Barry D. Blind study of the effect of the alpha-adrenergic agonists clonidine and lofexidine on alcohol withdrawal in the rat. J. Stud. Alcohol 1984; 45: 310–315
   PubMed Web of Science ®Google Scholar
• Manhem P., Nilsson L. H., Moberg A. L., Wadstein J., Hokfelt B. Alcohol withdrawal: Effects of clonidine treatment on sympathetic activity, the renin-aldosterone system, and clinical symptoms. Acoholism: Clin. Exp. Res. 1985; 4: 238–243
   Google Scholar
• Robinson B. J., Robinson G. M., Maling T. J. B., Johnson R. H. Is clonidine useful in the treatment of alcohol withdrawal?. Alcoholism: Clin. Exp. Res. 1989; 13: 95–98
   PubMed Web of Science ®Google Scholar
• Nutt D., Glue P., Molyneux S., Clark E. Alpha-2-adrenoceptor function in alcohol withdrawal: A pilot study of the effects of IV clonidine in alcoholics and normals. Alcoholism: Clin. Exp. Res. 1988; 12: 14–18
   PubMed Web of Science ®Google Scholar
• Baumgertner G. R., Rowen R. C. Clonidine vs chlordiazepoxide in the management of acute alcohol withdrawal syndrome. Arch. Intern. Med. 1987; 147: 1223–1226
   PubMedGoogle Scholar
• Glue P., Nutt D. Clonidine in alcohol withdrawal: A pilot study of differential symptom responses following I.V. clonidine. Alcohol Alcoholism 1987; 22: 161–166
   PubMed Web of Science ®Google Scholar
• Cushman P., Forbes R., Lerner W., Stewart M. Alcohol withdrawal syndromes: Clinical management with lofexidine. Alcoholism: Clin. Exp. Res. 1985; 9: 103–107
   PubMed Web of Science ®Google Scholar
• Horowitz R. I., Gottlieb L. D., Kraus M. L. The efficacy of atenolol in the outpatient management of the alcohol withdrawal syndrome. Arch. Intern. Med. 1989; 149: 1089–1093
   PubMedGoogle Scholar
• Sellers E. M., Zilm D. H., Degani N. C. Comparative efficacy of propranolol and chlordiazepoxide in alcohol withdrawal. J. Stud. Alcohol 1977; 38: 2096–2108
   PubMed Web of Science ®Google Scholar
• Kraus M. L., Gottleib L. D., Horowitz R. I., Anscher M. Randomized clinical trial of atenolol in patients with alcohol withdrawal. New Engl. J. Med. 1985; 313: 905–909
   PubMed Web of Science ®Google Scholar
• Zechnich R. J. Beta blockers can obscure diagnosis of delirium tremens. Lancet 1982; 1: 1071–1072
   PubMed Web of Science ®Google Scholar
• Jacob M. S., Zilm D. H., Macleod S. M., Sellers E. M. Propranolol-associated confused states during alcohol withdrawal. J. Clin. Psychopharmacol. 1983; 3: 185–187
   PubMed Web of Science ®Google Scholar
• Malcolm R., Ballenger J. C, Sturgis E. T., Anton R. Double-blind controlled trial comparing carbamazepine to oxazepam treatment of alcohol withdrawal. Am. J. Psychiatry 1989; 146: 617–621
   PubMed Web of Science ®Google Scholar
• Shaw J. M., Kolesar G. S., Sellers E. M., Kaplan H. L., Sandor P. Development of optimal treatment tactics for alcohol withdrawal. I. Assessment and effectiveness of supportive care. J. Clin. Psychopharmacol. 1981; 1: 382–387
   PubMed Web of Science ®Google Scholar
• Sullivan J. T., Sykora K., Schneiderman J., Naranjo C. A., Sellers E. M. Assessment of alcohol withdrawal: The revised clinical institute withdrawal assessment for alcohol scale (CrWA-Ar). Br. J. Addict. 1989; 84: 1353–1357
   PubMedGoogle Scholar
• Gross M. M., Lewis E., Nagarajan M. The Anatomy of the Acute Alcohol Withdrawal States and Its Application to the Evaluation of Treatment. Presented at the 125th Annual Meeting. American Psychiatric Association, Dallas, Texas 1972
   Google Scholar