503
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Staurosporine induces apoptosis and necroptosis in cultured rat astrocytes

&
Pages 399-405 | Received 05 May 2011, Accepted 13 Oct 2011, Published online: 29 Feb 2012

References

  • Belmokhtar, C. A., Hillion, J., Ségal-Bendirdjian, E. (2001). Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms. Oncogene 20:3354–3362.
  • Cho, Y. S., Challa, S., Moquin, D., Genga, R., Ray, T. D., Guildford, M., et al. (2009). Phosphorylation driven assembly of the RIP1 RIP3 complex regulates programmed necrosis and virus induced inflammation. Cell 137:1112–1123.
  • D’Alimonte, I., Ballerini, P., Nargi, E., Buccella, S., Giuliani, P., Di Iorio, P., et al. (2007). Staurosporine-induced apoptosis in astrocytes is prevented by A1 adenosine receptor activation. Neurosci Lett 418:66–71.
  • Degterev, A., Huang, Z., Boyce, M., Li, Y., Jagtap, P., Mizushima, N., et al. (2005). Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2:112–119.
  • Degterev, A., Hitomi, J., Germscheid, M., Ch’en, I. L., Korkina, O., Teng, X., et al. (2008). Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 5:313–321.
  • Falsig, J., Latta, M., Leist, M. (2004). Defined inflammatory states in astrocyte cultures: correlation with susceptibility towards CD95-driven apoptosis. J Neurochem 1:181–193.
  • He, S., Wang, L., Miao, L., Wang, T., Du, F., Zhao, L., et al. (2009). Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 137:1100–1111.
  • Holler, N., Zaru, R., Micheau, O., Thome, M., Attinger, A., Valitutti, S., et al. (2000). Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 6:489–495.
  • Ishizaki, Y., Cheng, L., Mudge, A. W., Raff, M. C. (1995). Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells. Mol Biol Cell 6:1443–1458.
  • Kroemer, G., Galluzzi, L., Vandenabeele, P., Abrams, J., Alnemri, E. S., Baehrecke, E. H., et al. (2009). Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ 16:3–11.
  • Kumar, S. (2007). Caspase function in programmed cell death. Cell Death Differ 14:32–43.
  • Laird, M. D., Wakade, C., Alleyne, C. H., Dhandapani, K. M. (2008). Hemin induced necroptosis involves glutation depetion in mouse astrocytes. Free Radic Biol Med 45:1103–1114.
  • Martin, S. J., Reutelingsperger, C. E. M., McGahon, A. J., Rader, J. A., van Schie, R. C. A. A., LaFace, D. M., et al. (1995). Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J Exp Med 182:1545–1556.
  • Schmid, I., Uittenbogaart, C. H., Keld, B., Giorgi, J. V. (1994). A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry. J Immunol Methods 170:145–157.
  • Seth, P., Koul, N. (2008). Astrocyte, the star avatar: redefined. J Biosci 33:405–421.
  • Song, J. H., Bellail, A., Tse, M. C. L., Wee Yong, V., Hao, C. (2006). Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis inducing ligand induced apoptosis. J Neurosci 26:3299–3308.
  • Stepczynska, A., Lauber, K., Engels, I. H., Janssen, O., Kabelitz, D., Wesselborg, S., et al. (2001). Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation. Oncogene 20:1193–1202.
  • Takuma, K., Baba, A., Matsuda, T. (2004). Astrocyte apoptosis: implications for neuroprotection. Prog Neurobiol 72:111–127.
  • Taylor, R. C., Cullen, S. P., Martin, S. J. (2008). Apoptosis: controlled demolition at the cellular level. Nat Rev Cell Mol Biol 9:231–241.
  • Ting, A. T., Pimentel-Muiños, F. X., Seed, B. (1996). RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1 initiated apoptosis. EMBO J 15:6189–6196.
  • Vercammen, D., Brouckaert, G., Denecker, G., van de Craen, M., Declercq, W., Fiers, W., et al. (1998). Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways. J Exp Med 188:919–930.
  • Vermes, I., Haanen, C., Steffens-Nakken, H., Reutelingsperger, C. (1995). A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 184:39–51.
  • Wang, L., Du, F., Wang, X. (2008). TNF-α induces two distinct capsase 8 activation pathways. Cell 133:693–703.
  • Xue, L. Y., Chiu, S. M., Oleinick, N. L. (2003). Staurosporine-induced death of MCF-7 human breast cancer cells: a distinction between caspase-3 dependent steps of apoptosis and the critical lethal lesions. Exp Cell Res 283:135–145.
  • Zhang, D. W., Shao, J., Lin, J., Zhang, N., Lu, B. J., Lin, S. C., et al. (2009). RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325:332–336.
  • Zhang, X. D., Gillespie, S. K., Hersey, P. (2004). Staurosporine induces apoptosis of melanoma by both caspase dependent and independent apoptotic pathways. Mol Cancer Ther 3:187–197.
  • Zong, W. X., Thompson, C. B. (2006). Necrotic death as a cell fate. Genes Dev 20:1–15

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.