References
- Ayres M, Ayres MJ, Ayres DL, Santos AS. (2005). Bioestat 5.0: aplicações estatísticas nas áreas das ciências biomédicas [Bioestat 5.0: Statistical applications in areas of biomedical sciences]. Belém, Pará: Sociedade Civil Mamirauá, MCT-CNPq
- Bolaños-Díaz R, Zavala-Gonzales JC, Mezones-Holguín E, Francia-Romero J. (2011). Soy extracts versus hormone therapy for reduction of menopausal hot flushes: indirect comparison. Menopause 18:825–829
- Carmignani LO, Pedro AO, Costa-Paiva LH, Pinto-Neto AM. (2010). The effect of dietary soy supplementation compared to estrogen and placebo on menopausal symptoms: a randomized controlled trial. Maturitas 67:262–269
- Chen WF, Huang MH, Tzang CH, et al. (2003). Inhibitory actions of genistein in human breast cancer (MCF-7) cells. Biochim Biophys Acta 1638:187–196
- Denton H, McGregor JC, Coombs GH. (2004). Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1. Biochem J 381:405–412
- Dimicheli C, Frézard F, Lecouvey M, Garnier-Suillerot A. (2002). Antimony(V) complex formation with adenine nucleosides in aqueous solution. Biochim Biophys Acta 1570:192–198
- Ding WH, Liu YH. (2011). Genistein attenuates genioglossus muscle fatigue under chronic intermittent hypoxia by down-regulation of oxidative stress level and up-regulation of antioxidant enzyme activity through ERK1/2 signaling pathway. Oral Disease 17:677–684
- Duncam AM, Phipps WR, Kurzer MS. (2003). Phyto-oestrogens. Best Pract Res Clin Endocrinol Metab 17:253–271
- Erba D, Casiraghi MC, Martinez-Conesa C, et al. (2012). Isoflavone supplementation reduces DNA oxidative damage and increases O-β-N-acetyl-d-glucosaminidase activity in healthy women. Nutr Res 32:233–240
- Ferguson LR. (2001). Role of plant polyphenols in genomic stability. Mutat Res 475:89–111
- Fox JT, Sakamuru S, Huang R, et al. (2012). High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci USA 109:5423–5428
- Frezard F, Demicheli C, Ferreira CS, Costa MAP. (2001). Glutathione-induced conversion of pentavalent antimony to trivalent antimony in meglumine antimoniate. Antimicrob Agents Chemother 45:913–916
- Frezard F, Demicheli C, Ribeiro RR. (2009). Pentavalent antimonials: new perspectives for old drugs. Molecules 30:2317–2336
- Hagen MK, Ludke A, Araujo AS, et al. (2012). Antioxidant characterization of soy derived products in vitro and the effect of a soy diet on peripheral markers of oxidative stress in a heart disease model. Can J Physiol Pharmacol 90:1095–1103
- Haldar AK, Sen P, Roy S. (2011). Use of antimony in the treatment of leishmaniasis: current status and future directions. Mol Biol Int 2011:1–23
- Heddle JA. (1973). A rapid in vivo test for chromosomal damage. Mutat Res 18:187–190
- Iovine B, Iannella ML, Gasparri F, et al. (2011). Synergic effect of genistein and daidzein on UVB-induced DNA damage: an effective photoprotective combination. J Biomed Biotechnol 2011:1–8
- Jian L. (2009). Soy, isoflavones, and prostate cancer. Mol Nutr Food Res 53:217–226
- Kalaiselvan V, Kalaivani M, Vijayakumar A, et al. (2010). Current knowledge and future direction of research on soy isoflavones as a therapeutic agents. Pharmacogn Rev 4:111–117
- Kang T, Liang M. (1997). Studies on the inhibitory effects of quercetin on the growth of HL460 leukemia cells. Bioch Pharmacol 54:1013–1018
- Kim EJ, Shin HK, Park JH. (2005). Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of genistein. J Med Food 8:431–438
- Lehmann L, Esch HL, Wagner J, et al. (2005). Estrogenic and genotoxic potential of equol and two hydroxylated metabolites of daidzein in cultured human Ishikawa cells. Toxicol Lett 158:72–86
- Levis S, Strickman-Stein N, Ganjei-Azar P, et al. (2011). Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms: a randomized, double-blind trial. Arch Intern Med 171:1363–1369
- Lima MIS, Arruda VO, Alves EVC, et al. (2010). Genotoxic effects of the antileishmanial drug Glucantime®. Arch Toxicol 84:227–232
- Liu J, Chang SK, Wiesenborn D. (2005). Antioxidant properties of soybean isoflavone extract and tofu in vitro and in vivo. J Agric Food Chem 53:2333–2340
- Luo H, Jiang BH, King SM, Chen YC. (2008). Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids. Nutr Cancer 60:800–809
- Michels G, Watjen W, Niering P, et al. (2005). Pro-apoptotic effects of the flavonoid luteolin in rat H4IIE cells. Toxicol 206:337–348
- Molla MD, Hidalgo-Mora JJ, Soteras MG. (2011). Phytotherapy as alternative to hormone replacement therapy. Front Biosci (Schol Ed) 3:191–204
- Mookerjee Basu J, Mookerjee A, Sen P, et al. (2006). Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogenactivated protein kinase activation in Leishmania donovani infected macrophages. Antimicrob Agents Chemother 50:1788–1797
- Oliveira LF, Schubach AO, Martins MM, et al. (2011). Systematic review of the adverse effects of cutaneous leishmaniasis treatment in the New World. Acta Trop 118:87–96
- Park JS, Jung JS, Jeong YH, et al. (2011). Antioxidant mechanism of isoflavone metabolites in hydrogen peroxide-stimulated rat primary astrocytes: critical role of hemeoxygenase-1 and NQO1 expression. J Neurochem 119:909–919
- Roberts WL, Mcmurray WJ, Rainey PM. (1998). Characterization of the antimonial antileishmanial agent meglumine antimonate (Glucantime). Antimicrob Agents Chemother 42:1075–1082
- Romagnolo DF, Selmin OI. (2012). Flavonoids and cancer prevention: a review of the evidence. J Nutr Gerontol Geriatr 31:206–238
- Sato Y, Itagaki S, Oikawa S, et al. (2011). Protective effect of soy isoflavone genistein on ischemia-reperfusion in the rat small intestine. Biol Pharm Bull 34:1448–1454
- Sereno D, Holzmuller P, Mangot I, et al. (2001). Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes. Antimicrob Agents Chemother 45:2064–2068
- Sha GH, Lin SQ. (2008). Genistein inhibits proliferation of human endometrial endothelial cell in vitro. Chin Med Sci J 23:49–53
- Sierens J, Hartley JA, Campbell MJ, et al. (2002). In vitro isoflavone supplementation reduces hydrogen peroxide-induced DNA damage in sperm. Teratog Carcinog Mutagen 22:227–234
- Singh NP, Mccoy MT, Tice RR, Schneider EL. (1988). A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184–191
- Somjen D, Grafi-Cohen M, Weisinger G, et al. (2012). Growth inhibition of human thyroid carcinoma and goiter cells in vitro by the isoflavone derivative 7-(O)-carboxymethyl daidzein conjugated to N-t-Boc-hexylenediamine. Thyroid 22:809–813
- Speit G, Hartmann A. (1995). The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (Comet assay). Mutagenesis 10:555–559
- Sundar S, Chakravarty J. (2010). Antimony toxicity. Int J Environ Res Public Health 7:4267–4277
- Szkutnik-Fiedler D, Jedrzejczyk M, Grześkowiak E, et al. (2010). The role of phytoestrogen therapy in relieving postmenopausal symptoms. Ginekol Pol 81:929–934
- Valencia C, Arévalo J, Dujardin JC, et al. (2012). Prediction score for antimony treatment failure in patients with ulcerative leishmaniasis lesions. PLoS Negl Trop Dis 6:1656–1662
- Van Zanden JJ, Hamman OB, van Iersel MLPS, et al. (2003). Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin. Chem Biol Interact 145:139–148
- Waters MD, Brady AL, Stack HF, Brockman HE. (1990). Antimutagenicity profiles for some model compounds. Mutat Res 238:57–85
- Wei H, Bowen R, Cai Q, et al. (1995). Antioxidant and antipromotional effects of the soybean isoflavone genistein. Proc Soc Exp Biol Med 208:124–130
- Widyarini S, Domanski D, Painter N, Reeve VE. (2012). Photoimmune protective effect of the phytoestrogenic isoflavonoid equol is partially due to its antioxidant activities. Photochem Photobiol Sci 11:1186–1192
- Yen GC, Lai HH. (2003). Inhibition of reactive nitrogen species effets in vitro and in vivo by isoflavones and soy-based food extracts. J Agric Food Chem 57:7892–7900
- Zhou Y, Messier N, Ouellette M, et al. (2004). Leishmania major LmACR2 is a pentavalent antimony reductase that confers sensitivity to the drug Pentostam. J Biol Chem 279:37445–37451