Drug and Chemical Toxicology, Volume 38, Issue 3 (2015)

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Drug and Chemical Toxicology, Volume 38, Issue 3 (2015)

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Review Article

The effects of Andrographis paniculata (Burm.f.) Nees extract and diterpenoids on the CYP450 isoforms’ activities, a review of possible herb–drug interaction risks
Mei Lan Tan & Lin Ee Lim
Pages: 241-253
Published online: 26 Aug 2014
AbstractforThe effects of Andrographis paniculata (Burm.f.) Nees extract and diterpenoids on the CYP450 isoforms’ activities, a review of possible herb–drug interaction risks | Full Text | References | PDF (163 KB)
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Original Article

Evaluating the Teratogenicity of Ritodrine and Nifedipine using a Frog Embryo Teratogenesis assay (FETAX)
Ayper Boğa Pekmezekmek, Uğur Seçil Binokay, Mehmet Ata Seçilmiş, Eda Kumcu, Erhan Şimşek, Kübra Akillioğlu, Yaşar Sertdemir & Besim Özaykan
Pages: 254-265
Published online: 26 Aug 2014
AbstractforEvaluating the Teratogenicity of Ritodrine and Nifedipine using a Frog Embryo Teratogenesis assay (FETAX) | Full Text | References | PDF (1 MB)
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Research Article

The in vitro genotoxic and cytotoxic effects of remeron on human peripheral blood lymphocytes
Mostafa Norizadeh Tazehkand & Mehmet Topaktas
Pages: 266-271
Published online: 26 Aug 2014
AbstractforThe in vitro genotoxic and cytotoxic effects of remeron on human peripheral blood lymphocytes | Full Text | References | PDF (280.6 KB)
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Original Paper

Relative potencies of three glucocorticoids to induce hypoplasia of the physis and concomitant biochemical alterations in the rat
Boška Hrvačić, Kristina Šitum, Koraljka Đurić, Berislav Bošnjak, Željko Ferenčić, Karmen Brajša, Stribor Marković & Ines Glojnarić
Pages: 272-277
Published online: 11 Aug 2014
AbstractforRelative potencies of three glucocorticoids to induce hypoplasia of the physis and concomitant biochemical alterations in the rat | Full Text | References | PDF (371.4 KB)
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Research Article

Oxidative stress and biochemical responses in the tissues of African catfish Clarias gariepinus juvenile following exposure to primextra herbicide
Christopher Didigwu Nwani, Charles Tobechukwu Ifo, Helen Ogochukwu Nwamba, Vincent Chikwendu Ejere, Grace Chinenye Onyishi, Stanley Ndubuisi Oluah, Ogbonnaya Egbe Ikwuagwu & Gregory Ejike Odo
Pages: 278-285
Published online: 13 Aug 2014
AbstractforOxidative stress and biochemical responses in the tissues of African catfish Clarias gariepinus juvenile following exposure to primextra herbicide | Full Text | References | PDF (223 KB)
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Proteomic analysis reveals KRIT1 as a modulator for the antioxidant effects of valproic acid in human bone-marrow mesenchymal stromal cells
Kyoung Hwa Jung, Dal Mu Ri Han, Sin-Gu Jeong, Mi Ran Choi, Young Gyu Chai & Goang-Won Cho
Pages: 286-292
Published online: 09 Sep 2014
AbstractforProteomic analysis reveals KRIT1 as a modulator for the antioxidant effects of valproic acid in human bone-marrow mesenchymal stromal cells | Full Text | References | PDF (1.1 MB) | Supplemental
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Protective effects of Scutellaria lindbergii root extract against oxidative-induced cell and DNA damage in mouse fibroblast-like cells
Melika Ehtesham-Gharaee, Ameneh Eshaghi, Susan Shojaee, Javad Asili, Seyed Ahmad Emami, Javad Behravan & Fatemeh Mosaffa
Pages: 293-299
Published online: 19 Sep 2014
AbstractforProtective effects of Scutellaria lindbergii root extract against oxidative-induced cell and DNA damage in mouse fibroblast-like cells | Full Text | References | PDF (297.1 KB)
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Original Article

Acute toxicity studies of a novel excipient arabinoxylan isolated from Ispaghula (Plantago ovata) husk
Alia Erum, Sajid Bashir, Shazia Saghir, Ume Ruqia Tulain, Uzma Saleem, Muhammad Nasir, Farina Kanwal & Muhammad Nasir Hayat malik
Pages: 300-305
Published online: 09 Sep 2014
AbstractforAcute toxicity studies of a novel excipient arabinoxylan isolated from Ispaghula (Plantago ovata) husk | Full Text | References | PDF (538.7 KB)
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Research Article

Genotoxic evaluation of terbinafine in human lymphocytes in vitro
Danielle Tolomeotti, Marialba Avezum Alves de Castro-Prado, Juliane Rocha de Sant’Anna, Ana Beatriz Tozzo Martins & Valter Augusto Della-Rosa
Pages: 306-311
Published online: 18 Sep 2014
AbstractforGenotoxic evaluation of terbinafine in human lymphocytes in vitro | Full Text | References | PDF (159.7 KB)
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Article
Soy isoflavones have antimutagenic activity on DNA damage induced by the antileishmanial Glucantime (meglumine antimoniate)
Ludymila Furtado Cantanhêde, Laís Pinheiro Almeida, Rossy-Eric Pereira Soares, Patrícia Valéria Gomes Castelo Branco & Silma Regina Ferreira Pereira
Pages: 312-317
Published online: 30 Sep 2014
AbstractforSoy isoflavones have antimutagenic activity on DNA damage induced by the antileishmanial Glucantime (meglumine antimoniate) | Full Text | References | PDF (133.7 KB)
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Article
The effect of five artificial sweeteners on Caco-2, HT-29 and HEK-293 cells
Armorel Diane van Eyk
Pages: 318-327
Published online: 15 Oct 2014
AbstractforThe effect of five artificial sweeteners on Caco-2, HT-29 and HEK-293 cells | Full Text | References | PDF (434.1 KB)
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Article
Immunotoxicity assessment of sub-chronic oral administration of acetamiprid in Wistar rats
R. K. Shakthi Devan, P. C. Prabu & S. Panchapakesan
Pages: 328-336
Published online: 13 Oct 2014
AbstractforImmunotoxicity assessment of sub-chronic oral administration of acetamiprid in Wistar rats | Full Text | References | PDF (1.2 MB)
  • 308 Views
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Article
Assessment of cytotoxic and genotoxic potential of pyracarbolid by Allium test and micronucleus assay
Arzu Özkara, Dilek Akyıl, Yasin Eren, S. Feyza Erdoğmuş, Muhsin Konuk & Esra Sağlam
Pages: 337-341
Published online: 02 Oct 2014
AbstractforAssessment of cytotoxic and genotoxic potential of pyracarbolid by Allium test and micronucleus assay | Full Text | References | PDF (136.2 KB)
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Article
An in vivo assay of the mutagenic potential of imidacloprid using sperm head abnormality test and dominant lethal test
Preeti Bagri, Vinod Kumar & Anil Kumar Sikka
Pages: 342-348
Published online: 15 Oct 2014
AbstractforAn in vivo assay of the mutagenic potential of imidacloprid using sperm head abnormality test and dominant lethal test | Full Text | References | PDF (912.3 KB)
  • 172 Views
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Article
Using urinary 1-hydroxypyrene concentrations to evaluate polycyclic aromatic hydrocarbon exposure in women using biomass combustion as main energy source
Tania Ruíz-Vera, Lucia G. Pruneda-Alvarez, Francisco J. Pérez-Vázquez, Angeles C. Ochoa-Martínez, Sandra T. Orta-García, Cesar A. Ilizaliturri-Hernández & Iván N. Pérez-Maldonado
Pages: 349-354
Published online: 13 Oct 2014
AbstractforUsing urinary 1-hydroxypyrene concentrations to evaluate polycyclic aromatic hydrocarbon exposure in women using biomass combustion as main energy source | Full Text | References | PDF (269 KB)
  • 112 Views
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Article
Investigation of flurbiprofen genotoxicity and cytotoxicity in rat bone marrow cells
Taygun Timocin & Hasan B. Ila
Pages: 355-360
Published online: 13 Oct 2014
AbstractforInvestigation of flurbiprofen genotoxicity and cytotoxicity in rat bone marrow cells | Full Text | References | PDF (200.3 KB)
  • 200 Views
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