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Research Article

L-α-Acetylmethadol-Induced Tissue Alterations in Mice

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Pages 91-112 | Published online: 27 Sep 2008

References

  • Axelrod J. Possible mechanism of tolerance to narcotic drugs. Science (1956); 124: 236
  • Kato R., Gillete J. R. Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes. J. Pharmacol. Exp. Ther. (1965); 150: 285
  • Sladek N. E., Chaplin M. D., Mannering G. L. Sex-dependent differences in drug metabolism in the rat. IV. Effect of morphine administration. Drug Metab. Disp. (1973); 4: 244
  • Amzel V., van der Hoeven T. Morphine-induced depression of the hepatic microsomal drug-metabolizing enzyme-Effect on the lipid component. Biochem. Pharmacol. (1980); 29: 658
  • Guarantz D., Correia M. A. Morphine-mediated effects on rat hepatic heem and cytochrome P-450 in vivo, antagonism by naltrexone in the liver. Biochem. Pharmacol. (1981); 30: 1529
  • Buening M. K., Franklin M. R. SKF525-A inhibition, induction and 452-nm complex formation. Drug Metab. Disp. (1975); 4: 244
  • Franklin M. R. Inhibition of mixed function oxidations by substrate forming reduced cytochrome P-450 metabolic-intermediate complexes. Pharmac. Ther. A. (1977); 2: 227
  • Roberts S. M., Frankl M. R. Modification of hepatic microsomal oxidative metabolism in rats by the opiate maintenance drugs acetylmethadol, propoxyphene and methadone. Life Sci. (1979); 25: 845, it is
  • Gumbrecht J. R., Franklin M. R. The formation of cytochrome P-450-metabolic intermediate complexes from amines, in the isolated perfused liver. Xenobiotica (1979); 9: 547
  • Masten L. W., Peterson G. R., Burkhalter A., Way E. L. Tolerance to methadone lethality and microsomal enzyme induction in mice tolerant to and dependent on morphine. Drug Alcohol Dep. (1980); 5: 27
  • Datta R. K., Johnson E. A., Stenger R. J. Effects of morphine sulfate on NAPH-cytochrome C reductase and cytochrome P-450 of mouse liver microsomes. Arch. Int. Pharmacodyn. (1976); 223: 180
  • Masten L. W., Price S. R., Burnett C. J. Microsomal enzyme induction following repeated oral administration of LAAM. Res. Commun. Chem. Pathol. Pharmacol. (1978); 20: 1
  • Peterson G. R., Hostitler R. M., Lehman T., Covault H. P. Acute inhibition of oxidative drug metabolism by propoxyphene (Darvon). Biochem. Pharmacol. (1979); 28: 1783
  • Jollow D. J., Smith C. Biochemical aspects of toxic metabolites—Formation, detoxication and covalent binding. “Biological Reactive Intermediates”, D. J. Jollow, J. J. Kocsis, R. Snyder, H. Vainio. Plenum, New York (1972); 42
  • Hicks R., Hulbert P. B., Kurzeia E. N. Inhibition of induction of drug-metabolism in relation to dextro-propoxyphene-induced glutathione depletion in isolated hepatocytes. Proc. Br. Pharmaceut. Soc (1981); 3: 302
  • James R. C., Harbison R. D. Hepatic glutathione and hepatotoxicity. Effects on cytochrome P-450 complexing compounds SKF525-A, L-α-acetylmethadol (LAAM), norLAAM, and piperonyl butoxide. Biochem. Pharmacol. (1982); 31: 1829
  • James R. C., Goodman D. R., Harbison R. D. Hepatic glutathione and hepatotoxicity: Changes induced by selected narcotics. J. Pharmacol. Exp. Ther. (1982a); 221: 708
  • Meister A., Tate S. S. Glutathione and related γ-glutamyl compounds: Biosynthesis and utilization. Ann. Rev. Biochem. (1976); 45: 559
  • Cherubin C. E., Kane S., Weinburger D. R., Wolfe E., McGinn T. Persistence of transaminase abnormalities in former addicts. Ann. Int. Med. (1972); 76: 385
  • Kreek M. J., Dodes L., Kane S., Knobler J., Martin R. Long term methadone maintenance therapy: Effects on liver function. Ann. Int. Med. (1972); 77: 598
  • Klein N. C., Magida M. G. Propoxyphene hepatotoxicity. Dig. Dis. (1971); 16: 467
  • Lee T. H., Rees P. J. Hepatotoxicity of dextro-propoxyphene. Br. Med. J. (1977); 2: 296
  • Ostor A. G. The medical complications of narcotic addiction. Med. J. Aust. (1977); 1: 497
  • Norris R. F., Potter H. P. Hepatic inflammation in narcotic addicts. Viral hepatitis a possible cause. Arch. Env. Health (1965); 11: 662
  • Gorodetzky C. W., Sapira J., Jasinski D. R., Martin W. R. Liver disease in narcotic addicts. I. The role of the drug. Clin. Pharmacol. Ther. (1968); 9: 720
  • Hurwitz A. Narcotic effects on anionic dye disposition in mice. Gastroenterol. (1979); 76: 1285
  • Thureson-Klein A., Wang-Yang J., Ho I. K. Lipid accumulation in mouse hepatocytes after morphine exposure. Experentia (1978); 34: 773
  • Chang Y. H., Ho I. K. Effects of acute and continuous morphine administration on serum glutamate oxalacetate transaminase and glutamate pyruvate transaminase activities in the mouse. Biochem. Pharmacol. (1979); 28: 1373
  • Needham W. P., Shuster L., Kanel G. C., Thompson M. L. Liver damage from narcotics in mice. Toxicol. Appl. Pharmacol. (1981); 58: 157
  • Ellman G. L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. (1959); 82: 70
  • Reitman S., Frankel S. A colorimetric method for the determination of serum glutamic-oxalacetic and glutamic-pyruvic transaminases. Am. J. Clin. Pathol. (1957); 28: 56
  • Tiffany T. O., Jansen J. M., Burtis C. A., Overton J. B., Scott C D. Enzymatic kinetic rate and end-point analyses of substrate, by use of GeMSAEC fast analyzer. Clin. Chem. (1972); 18: 829
  • Fabiny D. L., Ertingshausen G. Automated reaction-rate method for determination of serum creatinine with the Centrifichem. Clin. Chem. (1971); 17: 697
  • Emmerson J. L., Gison W. R., Harris P. N., Todd G. C., Pierce E. C., Anderson R. C. Short-term toxicity of propoxyphene salts in rats and dogs. Toxicol. Appl. Pharmacol. (1971); 19: 452
  • Hogberg J., Kristoferson A. A correlation between glutathione levels and cellular damage in isolated hepatocytes. Eur. J. Biochem. (1977); 74: 77
  • Mukhtar H., Bend J. R. Serum glutathione-S-transferase: Perinatal development, sex differences, and effect of carbon tetrachloride administration on enzyme activity in the rat. Life Sci. (1977); 21: 1277
  • Mitchell J. R., Jollow D. J., Potter W. Z., Gillette J. R., Brodie B. B. Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J. Pharmacol. Exp. Ther. (1973); 187: 211
  • Evans M. A., Harbison R. D. Cocaine-induced hepatic necrosis in mice. Toxicol. Appl. Pharmacol. (1978); 45: 739
  • Docks E. L., Krishna G. Role of glutathione in chloroform-induced hepatotoxicity. Exp. Mol. Pathol. (1976); 24: 13
  • Reitz K. C., Steele W. J. Mechanism of inhibition of protein synthesis by morphine in rat brain and liver. Mol. Pharmacol. (1982); 22: 706

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