Neutrophil-rich Gastric Carcinomas: Light and Electron Microscopic Study of 9 Cases with Particular Reference to Neutrophil Apoptosis

References

• Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26: 239–57
   PubMed Web of Science ®Google Scholar
• Kroemer G, Galluzzi L, Vandenabeele P, et al. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 2009;16: 3–11
   PubMed Web of Science ®Google Scholar
• Savill JS, Wyllie AH, Henson JE, et al. Macrophage phagocytosis of aging neutrophils in inflammation: programmed cell death in the neutrophil leads to its recognition by macrophages. J Clin Invest 1989;83: 865–75
   PubMed Web of Science ®Google Scholar
• Serhan CN, Savill J. Resolution of inflammation: the beginning programs the end. Nat Immunol 2005;6: 1191–7
   PubMed Web of Science ®Google Scholar
• Caruso RA, Speciale G, Inferrera C. Neutrophil interaction with tumour cells in small early gastric cancer: ultrastructural observations. Histol Histopathol 1994;9: 295–303
   PubMed Web of Science ®Google Scholar
• Caruso RA, Bellocco R, Pagano M, et al. Prognostic value of intratumoral neutrophils in advanced gastric carcinoma in a high-risk area in northern Italy. Mod Pathol 2002;15: 831–7
   PubMed Web of Science ®Google Scholar
• Caruso RA, Bonanno A, Finocchiaro G, Cavaliere R. Ultrastructural observations on inflammatory angiogenesis in gastric carcinomas with massive neutrophil infiltration. Ultrastruct Pathol 2009;33: 1–5
   PubMed Web of Science ®Google Scholar
• Rice AJ, Griffiths AP, Martin IG, Dixon MF. Gastric carcinoma with prominent neutrophil infiltration. Histopathology 2000;37: 289–90
   PubMedGoogle Scholar
• Caruso RA, Muda AO, Bersiga A, et al. Morphological evidence of neutrophil-tumor cell phagocytosis (cannibalism) in human gastric adenocarcinomas. Ultrastruct Pathol 2002;26: 315–21
   PubMed Web of Science ®Google Scholar
• Sobin LH, Wittekand CH, eds. TNM Classification of Malignant Tumors, 6th ed. New York: Wiley-Liss, 2002
   Google Scholar
• Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis: the updated Sydney system. International workshop on the histopathology of gastritis, Houston 1994. Am J Surg Pathol 1996;20: 1161–81
   PubMed Web of Science ®Google Scholar
• Correa P, Piazuelo MB. The gastric precancerous cascade. J Dig Dis 2012;13: 2–9
   PubMed Web of Science ®Google Scholar
• Mantovani A, Cassatella MA, Costantini C, Jaillon S. Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 2011;11: 519–31
   PubMed Web of Science ®Google Scholar
• Balkwill FR, Mantovani A. Cancer-related inflammation: common themes and therapeutic opportunities. Semin Cancer Biol 2012;22: 33–40
   PubMed Web of Science ®Google Scholar
• Fridlender ZG, Sun J, Kim S, et al. Polarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TAN. Cancer Cell 2009;16: 183–194
   PubMed Web of Science ®Google Scholar
• Fridlender ZG, Albelda SM. Tumor-associated neutrophils: friend or foe? Carcinogenesis 2012;33: 949–55
   PubMed Web of Science ®Google Scholar
• Kaplanski G, Marin V, Montero-Julian F, et al. IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation. Trends Immunol 2003;24: 25–9
   PubMed Web of Science ®Google Scholar
• Dinarello CA. Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Curr Opin Immunol 1991;3: 941–8
   PubMedGoogle Scholar
• Dinarello CA. The paradox of pro-inflammatory cytokines in cancer. Cancer Metastasis Rev 2006;25: 307–13
   PubMed Web of Science ®Google Scholar
• Borges VM, Vandivier RW, McPhillips KA, et al. TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation. Am J Physiol Lung Cell Mol Physiol 2009;297: L586–95
   Google Scholar
• Taylor EL, Rossi AG, Dransfield I, Hart SP. Analysis of neutrophil apoptosis. Methods Mol Biol 2007;412: 177–200
   PubMedGoogle Scholar
• Caruso RA, Fedele F, Finocchiaro G, et al. Neutrophil-tumor cell phagocytosis (cannibalism) in human tumors: an update and literature review. Exp Oncol 2012;34: 306–11
   PubMedGoogle Scholar
• Lugini L, Matarrese P, Tinari A, et al. Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells. Cancer Res 2006;66: 3629–38
   PubMed Web of Science ®Google Scholar
• Xia P, Wang S, Guo Z, Yao X. Emperipolesis, entosis and beyond: dance with fate. Cell Res 2008;18: 705–7
   PubMed Web of Science ®Google Scholar
• Payne CM, Glasser L, Tischler ME, et al. Programmed cell death of the normal human neutrophil: an in vitro model of senescence. Microsc Res Tech 1994;28: 327–44
   PubMed Web of Science ®Google Scholar
• Hébert MJ, Takano T, Holthöfer H, Brady HR. Sequential morphologic events during apoptosis of human neutrophils: modulation by lipoxygenase-derived eicosanoids. J Immunol 1996;157: 3105–15
   PubMed Web of Science ®Google Scholar
• Guejes L, Zurgil N, Deutsch M, et al. The influence of different cultivating conditions on polymorphonuclear leukocyte apoptotic processes in vitro, I: the morphological characteristics of PMN spontaneous apoptosis. Ultrastruct Pathol 2003;27: 23–32
   Google Scholar
• Guejes L, Zurgil N, Stambler I, et al. The influence of different cultivating conditions on polymorphonuclear leukocyte apoptotic process in vitro, II: ultrastructural characteristics of PMN populations incubated with proteinase 3 anti-neutrophil autoantibodies. Ultrastruct Pathol 2005;29: 37–51
   Web of Science ®Google Scholar
• Gilligan HM, Bredy B, Brady HR, Hébert MJ. Antineutrophil cytoplasmic autoantibodies interact with primary granule constituents on the surface of apoptotic neutrophils in the absence of neutrophil priming. J Exp Med 1996;184: 2231–41
   PubMed Web of Science ®Google Scholar
• Simon, HU. Neutrophil apoptosis pathways and their modifications in inflammation. Immunol Rev 2003;193: 101–10
   PubMed Web of Science ®Google Scholar