119
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Protective Reactivity and Alteration of the Brain Tissue in Alcoholics Evidenced by SOD1, MMP9 Immunohistochemistry, and Electron Microscopy

, MSci, , PhD, , , & , PhD
Pages 346-355 | Received 29 Apr 2013, Accepted 27 May 2013, Published online: 22 Jul 2013

References

  • Caputo F, Vignoli T, Leggio L, et al. Alcohol use disorders in the elderly: a brief overview from epidemiology to treatment options. Exp Gerontol 2012;47: 411–16
  • Syapin PJ, Brain damage and alcohol dependence: how one may influence the other. Alcohol Treat Q 2011;29:132–45
  • Kruman II, Henderson GI, Bergeson SE. DNA damage and neurotoxicity of chronic alcohol abuse. Exp Biol Med (Maywood) 2012;237: 740–7
  • Ji C. Mechanisms of alcohol-induced endoplasmic reticulum stress and organ injuries. Biochem Res Int 2012;2012:216450
  • Zelko IN, Mariani TJ, Folz RJ. Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med 2002;33: 337–49
  • Yon JM, Baek IJ, Lee SR, et al. Immunohistochemical identification and quantitative analysis of cytoplasmic Cu/Zn superoxide dismutase in mouse organogenesis. J Vet Sci 2008;9: 233–40
  • Linseman DA. Targeting oxidative stress for neuroprotection. Antioxid Redox Signal 2009;11: 421–4
  • Mattson MP. Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol 2000;1: 120–9
  • Maier CM. Role of superoxide dismutases in oxidative damage and neurodegenerative disorders. Neuroscientist 2002;8: 323–34
  • Uttara B, Singh AV, Zamboni P, Mahajan RT. Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol 2009;7: 65–74
  • Kocatürk PA, Akbostanci MC, Tan F, Kavas GÖ. Superoxide dismutase activity and zinc and copper concentrations in Parkinson's disease. Pathophysiology 2000;7: 63–7
  • Johnson F, Giulivi C. Superoxide dismutases and their impact upon human health. Mol Aspects Med 2005;26: 340–52
  • Floreani NA, Rump TJ, Abdul Muneer PM, et al. Alcohol-induced interactive phosphorylation of Src and toll-like receptor regulates the secretion of inflammatory mediators by human astrocytes. J Neuroimmune Pharmacol 2010;5: 533–45
  • Kim GW, Gasche Y, Grzeschik S, et al. Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood–brain barrier disruption? J Neurosci 2003;23: 8733–42
  • Lehner C, Gehwolf R, Tempfer H,et al. Oxidative stress and blood–brain barrier dysfunction under particular consideration of matrix metalloproteinases. Antioxid Redox Signal 2011;15: 1305–23
  • Rosenberg GA. Neurological diseases in relation to the blood–brain barrier. J Cereb Blood Flow Metab 2012;32: 1139–51
  • Rosenberg GA. Matrix metalloproteinases and their multiple roles in neurodegenerative diseases. Lancet Neurol 2009;8: 205–16
  • Kim EM, Hwang O. Role of matrix metalloproteinase-3 in neurodegeneration. J Neurochem 2011;116: 22–32
  • Sternlicht MD, Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 2001;17:463–516
  • Dityatev A, Seidenbecher CI, Schachner M. Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain. Trends Neurosci 2010;33: 503–12
  • Sternlicht MD, Bissell MJ, Werb Z. The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter. Oncogene 2000;19: 1102–13
  • Newman TA, Woolley ST, Hughes PM, et al. T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: involvement of metalloproteinases. Brain 2001;124: 2203–14
  • Yong VW. Metalloproteinases: mediators of pathology and regeneration in the CNS. Nat Rev Neurosci 2005;6: 931–44
  • Gupta VK. CSD, BBB and MMP-9 elevations: animal experiments versus clinical phenomena in migraine. Expert Rev Neurother 2009;9: 1595–614
  • Zhang H, Adwanikar H, Werb Z, Noble-Haeusslein LJ. Matrix metalloproteinases and neurotrauma: evolving roles in injury and reparative processes. Neuroscientist 2010;16: 156–70
  • Duran-Vilaregut J, del Valle J, Manich G, et al. Role of matrix metalloproteinase-9 (MMP-9) in striatal blood–brain barrier disruption in a 3-nitropropionic acid model of Huntington's disease. Neuropathol Appl Neurobiol 2011;37: 525–37
  • Seo JH, Miyamoto N, Hayakawa K, et al. Oligodendrocyte precursors induce early blood-brain–barrier opening after white matter injury. J Clin Invest 2013;123: 782–6
  • Yong VW, Power C, Forsyth P, Edwards DR. Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci 2001;2: 502–11
  • Pereira JA, Lebrun-Julien F, Suter U. Molecular mechanisms regulating myelination in the peripheral nervous system. Trends Neurosci 2012;35: 123–34
  • Milward E, Kim KJ, Szklarczyk A, et al. Cleavage of myelin associated glycoprotein by matrix metalloproteinases. J Neuroimmunol 2008;193: 140–8
  • Morita-Fujimura Y, Fujimura M, Gasche Y, et al. Overexpression of copper and zinc superoxide dismutase in transgenic mice prevents the induction and activation of matrix metalloproteinases after cold injury-induced brain trauma. J Cereb Blood Flow Metab 2000;20: 130–8
  • Vandooren J, Van den Steen PE, Opdenakker G. Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decade. Crit Rev Biochem Mol Biol 2013;48:222–72
  • Mizoguchi H, Yamada K, Nabeshima T. Matrix metalloproteinases contribute to neuronal dysfunction in animal models of drug dependence, Alzheimer's disease, and epilepsy. Biochem Res Int 2011;2011:681385
  • Hartung HP, Kieseier BC. The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system. J Neuroimmunol 2000;107: 140–7
  • Fields RD. White matter in learning, cognition and psychiatric disorders. Trends Neurosci 2008;31: 361–70
  • Bühler M, Mann K. Alcohol and the human brain: a systematic review of different neuroimaging methods. Alcohol Clin Exp Res 2011;35: 1771–93
  • Ullén F. Is activity regulation of late myelination a plastic mechanism in the human nervous system? Neuron Glia Biol 2009;5: 29–34
  • Harper C, Dixon G, Sheedy D, Garrick T. Neuropathological alterations in alcoholic brains. Studies arising from the New South Wales Tissue Resource Centre. Prog Neuropsychopharmacol Biol Psychiatry 2003;27: 951–61
  • Djordjević VB. Free radicals in cell biology. Int Rev Cytol 2004;237:57–89
  • Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000;408: 239–47
  • Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 2003;92: 827–39
  • Peluffo H, Acarin L, Faiz M, et al. Cu/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury. J Neuroinflamm 2005;2: 12
  • Rosenberg GA. Matrix metalloproteinases in neuroinflammation. Glia 2002;39: 279–91
  • Asahi M, Wang X, Mori T, et al. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 2001;21: 7724–32
  • Quarles RH. Myelin-associated glycoprotein (MAG): past, present and beyond. J Neurochem 2007;100: 1431–48
  • Rosenberg GA. Matrix metalloproteinases and neuroinflammation in multiple sclerosis. Neuroscientist 2002;8: 586–95
  • Kettenmann H, Kirchhoff F, Verkhratsky A. Microglia: new roles for the synaptic stripper. Neuron 2013;77: 10–18
  • Takeuchi Y, Miki T, Liu JQ, et al. Morphological evidence of an altered process of synaptic transcytosis in adult rats exposed to ethanol. Alcohol 2012;47: 671–6
  • Kobayashi H, Chattopadhyay S, Kato K, et al. MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage. Mol Cell Neurosci 2008;39: 619–27
  • Moore CS, Milner R, Nishiyama A, et al. Astrocytic tissue inhibitor of metalloproteinase-1 (TIMP-1) promotes oligodendrocyte differentiation and enhances CNS myelination. J Neurosci 2011;31: 6247–54
  • Mentlein R, Hattermann K, Held-Feindt J. Lost in disruption: role of proteases in glioma invasion and progression. Biochim Biophys Acta 2012;1825: 178–85
  • De la Monte SM. Disproportionate atrophy of cerebral white matter in chronic alcoholics. Arch Neurol 1988;45: 990–2

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.