In vitro and in vivo evaluations of PLGA microsphere vaccine formulations containing pDNA coexpressing Hepatitis B surface antigen and Interleukin-2

References

• Ando S, Putnam D, Pack DW, Langer R. PLGA microspheres containing plasmid DANN: Preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization. J Pharm Sci 1998; 88: 126–130
   Web of Science ®Google Scholar
• Boyer JD, Ugen KE, Wang B, Agadjanyani MG, Gilbert L, Bagarazzi ML, et al. Protection of chimpanzees from high-dose heterologous HIV-I challenge by DNA vaccination. Nature Med 1997; 3: 526–532
   PubMed Web of Science ®Google Scholar
• Choudary S, Ravikumar P, Ashok Kumar C, Suryanarayana VVS, Reddy GR. Enhanced immune response of DNA vaccine (VP1-pCDNA) adsorbed on cationic PLG for foot and mouth disease in guinea pig. Virus Genes 2008; 37: 81–87
   PubMedGoogle Scholar
• Chow YH, Huang WL, Chi WK, Chu YD, Tao MH. Improvement of Hepatitis B virus DNA vaccines by plasmids coexpressing Hepatitis B surface antigen and interleukin-2. J Virol 1997; 71: 169–179
   PubMed Web of Science ®Google Scholar
• Coelho-Castelo AA, Santos Junior RR, Bonato VDL, Jamur MC, Oliver C, Silva CL. B-lymphocytes in bone marrow or lymph nodes can take up plasmid DNA after intramuscular delivery. Human Gene Ther 2003; 14: 1279–1285
   PubMed Web of Science ®Google Scholar
• Dastan T, Turan K. In vitro characterization and delivery of chitosan-DNA microparticles into mammalian cells. J Pharm Pharm Sci 2004; 7: 205–214
   PubMed Web of Science ®Google Scholar
• Davis HL, Michel ML, Whalen RG. DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody. Human Molec Genet 1993; 2: 1847–1851
   PubMed Web of Science ®Google Scholar
• Denis-Mize KS, Dupuis M, MacKichan ML, Singh M, Doe B, O’Hagan D, et al. Plasmid DNA adsorbed onto cationic microparticles mediates target gene expression and antigen presentation by dendritic cells. Gene Therapy 2000; 7: 2105–2112
   PubMed Web of Science ®Google Scholar
• Dietrich G, Spreng S, Favre D, Viret JF, Guzman CA. Live attenuated bacteria as vectors to deliver plasmid DNA vaccines. Curr Opin Molec Ther 2003; 5: 10–19
   PubMed Web of Science ®Google Scholar
• Diez S, Tros de Ilarduya C. Versatility of biodegredabla poly(D;L-lactic-co-glycolic acid) microspheres for plasmid DNA delivery. Eur J Pharm Biopharm 2006; 63: 188–197
   PubMed Web of Science ®Google Scholar
• Espuelay S, Irache JM, Gamazo C. Synthetic particulate antigen delivery systems for vaccination. Immunologia 2005; 24: 208–223
   Google Scholar
• Fu K, Pack DW, Klibanow AM, Langer R. Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres. Pharm Res 2000; 17: 100–106
   PubMed Web of Science ®Google Scholar
• Garg S, Oran A, Wajchman J, Sasaki S, Maris CH, Kapp JA, et al. Genetic tagging shows increased frequency and longevity of antigen-presenting, skin derived dendritic cells in vivo. Nature Immunol 2003; 4: 907–912
   PubMedGoogle Scholar
• Gregoriadis G, Saffie R, Souza JB. Mediated DNA vaccination. FEBS Lett 1997; 402: 107–110
   PubMed Web of Science ®Google Scholar
• He XW, Wang F, Jiang L, Li J, Liu SK, Xiao ZY, et al. Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg. J Gen Virol 2005; 86: 601–610
   PubMed Web of Science ®Google Scholar
• Hedley ML, Gurley J, Urban R. Microspheres containing plasmid encoded antigens elicit cytotoxic T-cell responses. Nature Med 1998; 4: 365–368
   PubMed Web of Science ®Google Scholar
• Jaganathan KS, Vyas SP. Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant hepatitis B antigen administered intranasally. Vaccine 2006; 24: 4201–4211
   PubMed Web of Science ®Google Scholar
• Jeffry H, Stanley SS, O’Hagan DT. The preparation and characterization of poly(lactide-co-glycolide) microparticles. II. The entrapment of a model protein using a (water-in-oil)-in water emulsion solvent evaporation technique. Pharm Res 1993; 10: 362–368
   PubMedGoogle Scholar
• Jones DH, Corris S, McDonald S, Clegg JCS, Farrar GH. Poly (D,L-Lactic-co-glycolide) encapsulated plasmid DNA elicits systemic and mucosal antibody responses to encoded protein after oral administration. Vaccine 1997; 15: 814–817
   PubMed Web of Science ®Google Scholar
• Klencke B, Matijevic M, Urban RG, Lathey JL, Hedley ML, Berry M, et al. Encapsulated plasmid DNA treatment for human papilloma virus 16-associated anal displasia: A phase I study of ZYC101. Clin Cancer Res 2002; 8: 1028–1037
   PubMed Web of Science ®Google Scholar
• McClements WL, Armstrong ME, Keys RD, Liu MA. Immunization with DNA vaccines encoding glycoprotein D or glycoprotein B, alone or in combination, induces protective immunity in animal models of herpes simplex virus-2 disease. Proc Natl Acad Sci USA 1996; 93: 11414–11420
   PubMed Web of Science ®Google Scholar
• Mok H, Park TG. Direct plasmid DNA encapsulation within PLGA nanospheres by single oil-in-water emulsion method. Eur J Pharm Biopharm 2008; 68: 105–111
   PubMed Web of Science ®Google Scholar
• O’Donnell PB, McGinity JW. Preparation of microspheres by the solvent evaporation technique. Adv Drug Deliv Rev 1997; 28: 25–42
   PubMed Web of Science ®Google Scholar
• Pandit S, Cevher E, Zariwala MG, Somavarapu S, Alpar HO. Enhancement of immune response of HBsAg loaded poly (L-lactic acid) microspheres against hepatitis B through incorporation of alum and chitosan. J Microencapsulation 2007; 24: 539–552
   PubMed Web of Science ®Google Scholar
• Rosca ID, Watari I, Uo M. Microparticle formation and its mechanism in single and double emulsion solvent evaporation. J Contr Rel 2004; 99: 271–280
   PubMed Web of Science ®Google Scholar
• Sambrook J, Fritsch EF, Maniatis T. Plasmid vectors. Molecular cloning, J Sambrook, EF Fritsch, T Maniatis. Cold spring harbor laboratory press, New YorkUSA 1989; 1.33–1.40
   Google Scholar
• Shi L, Caulfield MJ, Chern RT, Wilson RA, Sanyal G, Volkin DB. Pharmaceutical and immunological evaluation of a single-shot hepatitis B vaccine formulated with PLGA microspheres. J Pharm Sci 2002; 91: 1019–1035
   PubMed Web of Science ®Google Scholar
• Singh M, Briones M, Ott G, O’Hagan D. Cationic microparticles: a potent delivery system for DNA vaccines. Proc Natl Acad Sci USA 2000; 97: 811–816
   PubMed Web of Science ®Google Scholar
• Tang DC, DeVith M, Johmston SA. Genetic immunization is a simple method for eliciting an immune responce. Nature 1992; 356: 152–154
   PubMed Web of Science ®Google Scholar
• Tinsley-Brown AM, Fretwell R, Dowsett AB, Davis SL, Farrar GH. Formulation of poly (D,L-Lactic-co-glycolic acid) microparticles for rapid plasmid DNA delivery. J Contr Rel 2000; 66: 229–241
   PubMed Web of Science ®Google Scholar
• Tuttenberg A, Jonuleit H, Tüting T, Brück J, Knop J, Enk AH. Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor specific CD8 T cells: Implications for an efficient vaccination strategy. Gene Ther 2003; 10: 243–250
   PubMedGoogle Scholar
• Ulmar JB, Donelly JJ, Parker SE, Rhode GH, Felgner PL, Dwarki V, et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993; 259: 1745–1749
   PubMedGoogle Scholar
• Walter E, Moelling K, Pavlovic J, Merkle HP. Microencapsulation of DNA using poly(D,L-lactic-co-glycolide): Stability issues and release characteristics. J Contr Rel 1999; 61: 361–374
   PubMed Web of Science ®Google Scholar
• Wang D, Robinson DR, Kwon GS, Samuel J. Encapsulation of plasmid DNA in biodegradable poly (D,L-Lactic-co-glycolic acid) microspheres as a novel approach for immunogene delivery. J Contr Rel 1999; 57: 9–18
   PubMed Web of Science ®Google Scholar
• Wang S, Liu X, Fisher K, Smith JG, Chen F, Tobery TW, et al. Enhanced type I immune response to a hepatitis B DNA vaccine by formulation with calcium or aluminium phosphate. Vaccine 2000; 18: 1227–1235
   PubMed Web of Science ®Google Scholar
• Wolff JA, Dowty ME, Jiao S, Repetto G, Berg RK, Ludtke JJ, et al. Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle. J Cell Sci 1992; 103: 1249–1259
   PubMed Web of Science ®Google Scholar
• Wolff JA, Malona RW, Williams P, Chong W, Acsadi G, Jani A, et al. Direct gene transfer into mouse muscle in vivo. Science 1990; 247: 1465–1468
   PubMed Web of Science ®Google Scholar
• Zhang W, Dong SF, Sun SH, Wang Y, Li GD, Qu D. Coimmunization with IL-15 plasmid enhances the longevity of CD8 T cells induced by DNA encoding hepatitis B virus core antigen. W J Gastroenterol 2006; 12: 4727–4735
   PubMed Web of Science ®Google Scholar