Development of a novel drug delivery system: chitosan nanoparticles entrapped in alginate microparticles

References

• Abdelwahed W, Degobert G, Stainmesse S, Fessi H. Freeze-drying of nanoparticles: Formulation, process and storage considerations. Adv Drug Deliv Rev, 2006;58(15):1688–713
   PubMed Web of Science ®Google Scholar
• Behrens I, Pena AI, Alonso MJ, Kissel T. Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: The effect of mucus on particle adsorption and transport. Pharm Res, 2002;19(8):1185–93
   PubMed Web of Science ®Google Scholar
• Bernkop-Schnurch A, Guggi D, Pinter Y. Thiolated chitosans: Development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery system. J Control Release, 2004;94(1):177–86
   PubMed Web of Science ®Google Scholar
• Berthold A, Cremer K, Kreuter J. Preparation and characterization of chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for antiinflammatory drugs. J Control Release, 1996;39(9):17–25
   Google Scholar
• Bihari P, Vippola M, Schultes S, Praetner M, Khandoga AG, Reichel CA, Coester C, Tuomi T, Rehberg M, Krombach F. Optimized dispersion of nanoparticles for biological in vitro and in vivo studies. Part Fibre Toxicol, 2008;5:14 . doi:10.1186/1743-8977-5-14
   PubMed Web of Science ®Google Scholar
• Borges O, Borchard G, Verhoef JC, de Sousa A, Junginger HE. Preparation of coated nanoparticles for a new mucosal vaccine delivery system. Int J Pharm, 2005;299(1–2):155–66
   PubMed Web of Science ®Google Scholar
• Carino GP, Mathiowitz E. Oral insulin delivery. Adv Drug Deliv Rev, 1999;35(2–3):249–57
   PubMed Web of Science ®Google Scholar
• Chen L, Subirade M. Effect of preparation conditions on the nutrient release properties of alginate-whey protein granular microspheres. Eur J Pharm Biopharm, 2007;65(3):354–62
   PubMed Web of Science ®Google Scholar
• Chen SC, Wu YC, Mi FL, Lin YH, Yu LC, Sung HW. A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. J Control Release, 2004;96(2):285–300
   PubMed Web of Science ®Google Scholar
• Cheng Q, Feng J, Chen J, Zhu X, Li F. Brain transport of neurotoxin-I with PLA nanoparticles through intranasal administration in rats: A microdialysis study. Biopharm Drug Dispos, 2008;29(8):431–9
   PubMed Web of Science ®Google Scholar
• Chickering DE, Jacob JS, Desai TA, Harrison M, Harris WP, Morrell CN, Chaturvedi P, Mathiowitz E. Bioadhesive microspheres: III. An in vivo transit and bioavailability study of drug-loaded alginate and poly(fumaric-co-sebacic anhydride) microspheres. J Control Release, 1997;48(1):35–46
   Web of Science ®Google Scholar
• Dambies L, Guimon C, Yiacoumi S, Guibal E. Characterization of metal ion interactions with chitosan by X-ray photoelectron spectroscopy. Colloids Surf, 2001;177:203–14
   Google Scholar
• Deacon MP, McGurk S, Roberts CJ, Williams PM, Tendler SJ, Davies MC, Davis SS, Harding SE. Atomic force microscopy of gastric mucin and chitosan mucoadhesive systems. Biochem J, 2000;348(Pt(3)):557–63
   PubMed Web of Science ®Google Scholar
• Douglas KL, Tabrizian M. Effect of experimental parameters on the formation of alginate–chitosan nanoparticles and evaluation of their potential application as DNA carrier. J Biomater Sci Polym Ed, 2005;16(1):43–56
   PubMed Web of Science ®Google Scholar
• Dulieu C, Bazile D. Influence of lipid nanocapsules composition on their aptness to freeze-drying. Pharm Res, 2005;22(2):285–92
   PubMed Web of Science ®Google Scholar
• Ermak TH, Giannasca PJ. Microparticle targeting to M cells. Adv Drug Deliv Rev, 1998;34(2–3):261–83
   PubMed Web of Science ®Google Scholar
• George M, Abraham TE. Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan – a review. J Control Release, 2006;114(1):1–14
   PubMed Web of Science ®Google Scholar
• Hillgren A, Alden M. A comparison between the protection of LDH during freeze-thawing by PEG 6000 and Brij 35 at low concentrations. Int J Pharm, 2002;244(1–2):137–49
   PubMed Web of Science ®Google Scholar
• Huang M, Ma Z, Khor E, Lim LY. Uptake of FITC-chitosan nanoparticles by A549 cells. Pharm Res, 2002;19(10):1488–94
   PubMed Web of Science ®Google Scholar
• Li XY, Jin LJ, McAllister TA, Stanford K, Xu JY, Lu YN, Zhen YH, Sun YX, Xu YP. Chitosan-alginate microcapsules for oral delivery of egg yolk immunoglobulin (IgY). J Agric Food Chem, 2007;55(8):2911–17
   PubMed Web of Science ®Google Scholar
• Liu P, Krishnan TR. Alginate-pectin-poly-l-lysine particulate as a potential controlled release formulation. J Pharm Pharmacol, 1999;51(2):141–9
   PubMed Web of Science ®Google Scholar
• Mladenovska K, Cruaud O, Richomme P, Belamie E, Raicki RS, Venier-Julienne MC, Popovski E, Benoit JP, Goracinova K. 5-ASA loaded chitosan-Ca-alginate microparticles: Preparation and physicochemical characterization. Int J Pharm, 2007;345(1–2):59–69
   PubMed Web of Science ®Google Scholar
• Ozbas-Turan S, Akbuga J, Aral C. Controlled release of interleukin-2 from chitosan microspheres. J Pharm Sci, 2002;91(5):1245–51
   PubMed Web of Science ®Google Scholar
• Suksamran T, Opanasopit P, Rojanarata T, Ngawhirunpat T. Development of alginate/chitosan microparticles for dust mite allergen. Trop J Pharmaceut Res, 2011;10(3):317–24
   Web of Science ®Google Scholar
• Takka S, Gurel A. Evaluation of chitosan/alginate beads using experimental design: Formulation and in vitro characterization. AAPS PharmSciTech, 2010;11(1):460–6
   PubMed Web of Science ®Google Scholar
• Wang JJ, Zeng ZW, Xiao RZ, Xie T, Zhou GL, Zhan XR, Wang SL. Recent advances of chitosan nanoparticles as drug carriers. Int J Nanomedicine, 2011;6:765–74
   PubMed Web of Science ®Google Scholar
• Wee S, Gombotz WR. Protein release from alginate matrices. Adv Drug Deliv Rev, 1998;31(3):267–85
   PubMed Web of Science ®Google Scholar
• Woitiski CB, Neufeld RJ, Veiga F, Carvalho RA, Figueiredo IV. Pharmacological effect of orally delivered insulin facilitated by multilayered stable nanoparticles. Eur J Pharm Sci, 2010;41(3–4):556–63
   PubMed Web of Science ®Google Scholar
• Wong TW. Chitosan and its use in design of insulin delivery system. Recent Pat Drug Deliv Formul, 2009;3(1):8–25
   PubMedGoogle Scholar
• Wong TW. Design of oral insulin delivery systems. J Drug Target, 2010;18(2):79–92
   PubMed Web of Science ®Google Scholar