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Research Article

Development and characterization of buoyant theophylline microspheres with near zero order release kinetics

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Pages 725-737 | Received 05 Feb 1998, Accepted 04 Mar 1998, Published online: 27 Sep 2008

References

  • Baker R. Controlled Release of Biologically Active Agents. John Wiley & Sons, New York 1987; 1–21
  • Bechard S., McMullen J. N. Solute release from a porous polymeric matrix: inwardly tapered disk with a central releasing hole. Journal of Pharmaceutical Sciences 1988; 77: 222–228
  • Bechgaard H. Design of controlled release products as adapted to gastrointestinal pH and transit time. Optimization of Drug Delivery, H. Benchgaard, A. B. Hansen, H. Kofod. Alfred Benzon Foundation, Copenhagen 1981; 67–79
  • Ch'ng H. S., Park H., Kelly P., Roberson J. R. Bioadhesive polymers as platforms for oral controlled drug delivery. 11. Synthesis and evaluation of some swelling, water-insoluble polymers. Journal of Pharmaceutical Sciences 1985; 74: 406–411
  • Desai S., Bolton S. A floating controlled-release drug delivery system: In vitro-in vivo evaluation. Pharmaceutical Research 1993; 10: 1321–1325
  • Harris D., Fell J. T., Sharma H. L., Taylor D. C. GI transit of potential bioadhesive formulations in man: a scintigraphic study. Journal of Controlled Release 1990; 12: 45–53
  • Ingani H. M., Timmermans J., Moes A. J. Conception and in vivo investigation of peroral sustained release dosage forms with enhanced gastrointestinal transit. International Journal of Pharmaceutics 1987; 35: 157–164
  • Kawashima Y., Niwa T., Takeuchi H., Hino T., Itoh Y. Hollow microspheres for use as a floating controlled drug delivery system in the stomach. Journal of Pharmaceutical Sciences 1992; 81: 135–140
  • Kim C. J. Compressed donut-shaped tablets with zero-order release kinetics. Pharmaceutical Research 1995; 12: 1045–1048
  • Lee P. I. Constant-rate drug release from novel anionic gel beads with transient composite structure. Journal of Pharmaceutical Sciences 1993; 82: 964–967
  • Menon A., Ritschel W. A., Sakr A. Development and evaluation of monolithic floating dosage form for furosemide. Journal of Pharmaceutical Sciences 1994; 83: 239–245
  • Moes A. J. Gastroretentive dosage forms. Critical Reviews in Therapeutic Drug Carrier Systems 1993; 10: 143–195
  • Oth M. P., Franz M., Timmermans J., Moes A. J. Bilayer floating capsule: a stomach directed drug delivery system for Misoprostol. Pharmaceutical Research 1992; 9: 298–302
  • Park K., Park H. Enzyme-digestible balloon hydrogels for long-term oral drug delivery: synthesis and characterization. Proceedings of International Symposium on Controlled Release of Bioactive Materials 1987; 14: 41–43
  • Rao K. V. R., Devi K. P., Buri P. Influence of molecular size and water solubility of the solute on its release from swelling and erosion controlled polymeric matrices. Journal of Controlled Release 1990; 12: 133–141
  • Saunders K. J. Cellulose and related polymers. Organic Polymer Chemistry, 2nd edition. Chapman & Hall, New York 1988; 286–315
  • Scott D. C., Hollenbeck R. G. Design and manufacture of a zero-order sustained-release pellet dosage form through nonuniform drug distribution in a diffusional matrix. Pharmaceutical Research 1991; 8: 156–161
  • Stithit S. Development and characterization of buoyant theophylline microspheres with near zero order dissolution kinetics. The University of Georgia. 1996, Ph.D Dissertation
  • Sugito K., Ogata H., Goto H., Noguchi M., Kogure T., Takano M., Maruyama Y., Sasaki Y. Gastrointestinal transit of non-disintegrating solid formulations in humans. International Journal of Pharmaceutics 1990; 60: 89–92
  • Zhang G., Schwartz J. B., Schnaare R. L. Bead coating. I. change in release kinetics (and mechanism) due to coating levels. Pharmaceutical Research 1991; 8: 331–335

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