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Original Articles

Hyperthermia and radiotherapy in the management of head and neck cancers: A systematic review and meta-analysis

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Pages 31-40 | Received 04 Jul 2015, Accepted 21 Sep 2015, Published online: 16 Nov 2015

References

  • Kodaira T, Nishimura Y, Kagami Y, Ito Y, Shikama N, Ishikura S, et al. Definitive radiotherapy for head and neck squamous cell carcinoma: Update and perspectives on the basis of EBM. Jpn J Clin Oncol 2015;45:235–43
  • Baujat B, Bourhis J, Blanchard P, Overgaard J, Ang KK, Saunders M, et al. Hyperfractionated or accelerated radiotherapy for head and neck cancer. Cochrane Database Syst Rev 2010;12:CD002026
  • Pignon JP, le Maitre A, Maillard E, Bourhis J, Group M-NC. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients. Radiother Oncol 2009;92:4–14
  • Levy AR, Johnston KM, Sambrook J, Donato B, Penrod JR, Corral M, et al. Indirect comparison of the efficacy of cetuximab and cisplatin in squamous cell carcinoma of the head and neck. Curr Med Res Opin 2011;27:2253–9
  • Overgaard J. Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – a systematic review and meta-analysis. Radiother Oncol 2011;100:22–32
  • Overgaard J. The heat is (still) on – the past and future of hyperthermic radiation oncology. Radiother Oncol 2013;109:185–7
  • Datta NR, Ordonez SG, Gaipl US, Paulides MM, Crezee H, Gellermann J, et al. Local hyperthermia combined with radiotherapy and/or chemotherapy: Recent advances and promises for the future. Cancer Treat Rev 2015;41:742–53
  • Dewhirst MW, Vujaskovic Z, Jones E, Thrall D. Re-setting the biologic rationale for thermal therapy. Int J Hyperthermia 2005;21:779–90
  • Song CW, Park H, Griffin RJ. Improvement of tumor oxygenation by mild hyperthermia. Radiat Res 2001;155:515–28
  • Jones EL, Prosnitz LR, Dewhirst MW, Marcom PK, Hardenbergh PH, Marks LB, et al. Thermochemoradiotherapy improves oxygenation in locally advanced breast cancer. Clin Cancer Res 2004;10:4287–93
  • Brizel DM, Scully SP, Harrelson JM, Layfield LJ, Dodge RK, Charles HC, et al. Radiation therapy and hyperthermia improve the oxygenation of human soft tissue sarcomas. Cancer Res 1996;56:5347–50
  • Thrall DE, Maccarini P, Stauffer P, Macfall J, Hauck M, Snyder S, et al. Thermal dose fractionation affects tumour physiological response. Int J Hyperthermia 2012;28:431–40
  • Vujaskovic Z, Poulson JM, Gaskin AA, Thrall DE, Page RL, Charles HC, et al. Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment. Int J Radiat Oncol Biol Phys 2000;46:179–85
  • Arcangeli G, Arcangeli G, Guerra A, Lovisolo G, Cividalli A, Marino C, et al. Tumour response to heat and radiation: Prognostic variables in the treatment of neck node metastases from head and neck cancer. Int J Hyperthermia 1985;1:207–17
  • Valdagni R, Amichetti M, Pani G. Radical radiation alone versus radical radiation plus microwave hyperthermia for N3 (TNM-UICC) neck nodes: A prospective randomized clinical trial. Int J Radiat Oncol Biol Phys 1988;15:13–24
  • Amichetti M, Romano M, Busana L, Bolner A, Fellin G, Pani G, et al. Hyperfractionated radiation in combination with local hyperthermia in the treatment of advanced squamous cell carcinoma of the head and neck: A phase I–II study. Radiother Oncol 1997;45:155–8
  • Valdagni R, Kapp DS, Valdagni C. N3 (TNM-UICC) metastatic neck nodes managed by combined radiation therapy and hyperthermia: Clinical results and analysis of treatment parameters. Int J Hyperthermia 1986;2:189–200
  • Kang M, Liu WQ, Qin YT, Wei ZX, Wang RS. Long-term efficacy of microwave hyperthermia combined with chemoradiotherapy in treatment of nasopharyngeal carcinoma with cervical lymph node metastases. Asian Pac J Cancer Prev 2013;14:7395–400
  • Hua Y, Ma S, Fu Z, Hu Q, Wang L, Piao Y. Intracavity hyperthermia in nasopharyngeal cancer: A phase III clinical study. Int J Hyperthermia 2011;27:180–6
  • Hiraki Y, Nakajo M, Miyaji N, Takeshita T, Churei H, Ogita M. Effectiveness of RF capacitive hyperthermia combined with radiotherapy for stages III and IV oro-hypopharyngeal cancers: A non-randomized comparison between thermoradiotherapy and radiotherapy. Int J Hyperthermia 1998;14:445–57
  • Wen QL, He LJ, Ren PR, Chen CQ, Wu JB. Comparing radiotherapy with or without intracavitary hyperthermia in the treatment of primary nasopharyngeal carcinoma: A retrospective analysis. Tumori 2014;100:49–54
  • Huilgol NG, Gupta S, Sridhar CR. Hyperthermia with radiation in the treatment of locally advanced head and neck cancer: A report of randomized trial. J Cancer Res Ther 2010;6:492–6
  • Valdagni R, Amichetti M. Report of long-term follow-up in a randomized trial comparing radiation therapy and radiation therapy plus hyperthermia to metastatic lymph nodes in stage IV head and neck patients. Int J Radiat Oncol Biol Phys 1994;28:163–9
  • Perez CA, Pajak T, Emami B, Hornback NB, Tupchong L, Rubin P. Randomized phase III study comparing irradiation and hyperthermia with irradiation alone in superficial measurable tumors. Final report by the Radiation Therapy Oncology Group. Am J Clin Oncol 1991;14:133–41
  • Datta NR, Bose AK, Kapoor HK, Gupta S. Head and neck cancers: Results of thermoradiotherapy versus radiotherapy. Int J Hyperthermia 1990;6:479–86
  • Arcangeli G, Benassi M, Cividalli A, Lovisolo GA, Mauro F. Radiotherapy and hyperthermia. Analysis of clinical results and identification of prognostic variables. Cancer 1987;60:950–6
  • Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration. BMJ 2009;339:b2700
  • Comprehensive Meta-analysis Software, version 3.0. Available from http://www.meta-analysis.com/index.php
  • IBM SPSS software. Available from http://www-01.ibm.com/support/docview.wss?uid=swg21608060
  • Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994;50:1088–101
  • Bonner JA, Harari PM, Giralt J, Cohen RB, Jones CU, Sur RK, et al. Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival. Lancet Oncol 2010;11:21–8
  • Marta GN, Silva V, de Andrade Carvalho H, de Arruda FF, Hanna SA, Gadia R, et al. Intensity-modulated radiation therapy for head and neck cancer: Systematic review and meta-analysis. Radiother Oncol 2014;110:9–15
  • Suntharalingam M, Haas ML, van Echo DA, Haddad R, Jacobs MC, Levy S, et al. Predictors of response and survival after concurrent chemotherapy and radiation for locally advanced squamous cell carcinomas of the head and neck. Cancer 2001;91:548–54
  • Hauswald H, Simon C, Hecht S, Debus J, Lindel K. Long-term outcome and patterns of failure in patients with advanced head and neck cancer. Radiat Oncol 2011;6:70
  • Michiels S, Le Maitre A, Buyse M, Burzykowski T, Maillard E, Bogaerts J, et al. Surrogate endpoints for overall survival in locally advanced head and neck cancer: Meta-analyses of individual patient data. Lancet Oncol 2009;10:341–50
  • Perez CA, Gillespie B, Pajak T, Hornback NB, Emami B, Rubin P. Quality assurance problems in clinical hyperthermia and their impact on therapeutic outcome: A report by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys 1989;16:551–8
  • Dewhirst MW, Phillips TL, Samulski TV, Stauffer P, Shrivastava P, Paliwal B, et al. RTOG quality assurance guidelines for clinical trials using hyperthermia. Int J Radiat Oncol Biol Phys 1990;18:1249–59
  • Bergs JW, Franken NA, Haveman J, Geijsen ED, Crezee J, van Bree C. Hyperthermia, cisplatin and radiation trimodality treatment: A promising cancer treatment? A review from preclinical studies to clinical application. Int J Hyperthermia 2007;23:329–41
  • Lohaus F, Linge A, Tinhofer I, Budach V, Gkika E, Stuschke M, et al. HPV16 DNA status is a strong prognosticator of loco-regional control after postoperative radiochemotherapy of locally advanced oropharyngeal carcinoma: Results from a multicentre explorative study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG). Radiother Oncol 2014;113:317–23
  • Pang E, Delic NC, Hong A, Zhang M, Rose BR, Lyons JG. Radiosensitization of oropharyngeal squamous cell carcinoma cells by human papillomavirus 16 oncoprotein E6 *I. Int J Radiat Oncol Biol Phys 2011;79:860–5
  • Xie X, Piao L, Bullock BN, Smith A, Su T, Zhang M, et al. Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma. Oncogene 2014;33:1037–46
  • Datta NR, Kumar P, Singh S, Gupta D, Srivastava A, Dhole TN. Does pretreatment human papillomavirus (HPV) titers predict radiation response and survival outcomes in cancer cervix? A pilot study. Gynecol Oncol 2006;103:100–5
  • Kim JY, Park S, Nam BH, Roh JW, Lee CH, Kim YH, et al. Low initial human papilloma viral load implicates worse prognosis in patients with uterine cervical cancer treated with radiotherapy. J Clin Oncol 2009;27:5088–93
  • Vozenin MC, Lord HK, Hartl D, Deutsch E. Unravelling the biology of human papillomavirus (HPV) related tumours to enhance their radiosensitivity. Cancer Treat Rev 2010;36:629–36
  • Datta NR, Singh S, Kumar P, Gupta D. Human papillomavirus confers radiosensitivity in cancer cervix: A hypothesis toward a possible restoration of apoptotic pathways based on clinical outcomes. Future Oncol 2015;11:1363–71
  • Oei AL, van Leeuwen CM, ten Cate R, Rodermond HM, Buist MR, Stalpers LJA, et al. Hyperthermia selectively targets human papillomavirus in cervical tumors via p53-dependent apoptosis. Cancer Res 2015 (in press)
  • Schmidtner J, Distel LV, Ott OJ, Nkenke E, Sprung CN, Fietkau R, et al. Hyperthermia and irradiation of head and neck squamous cancer cells causes migratory profile changes of tumour infiltrating lymphocytes. Int J Hyperthermia 2009;25:347–54
  • Masterson L, Moualed D, Liu ZW, Howard JE, Dwivedi RC, Tysome JR, et al. De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma: A systematic review and meta-analysis of current clinical trials. Eur J Cancer 2014;50:2636–48
  • Togni P, Rijnen Z, Numan WC, Verhaart RF, Bakker JF, van Rhoon GC, et al. Electromagnetic redesign of the HYPERcollar applicator: Toward improved deep local head-and-neck hyperthermia. Phys Med Biol 2013;58:5997–6009
  • Paulides MM, Stauffer PR, Neufeld E, Maccarini PF, Kyriakou A, Canters RA, et al. Simulation techniques in hyperthermia treatment planning. Int J Hyperthermia 2013;29:346–57
  • Verhaart RF, Fortunati V, Verduijn GM, van der Lugt A, van Walsum T, Veenland JF, et al. The relevance of MRI for patient modeling in head and neck hyperthermia treatment planning: A comparison of CT and CT-MRI based tissue segmentation on simulated temperature. Med Phys 2014;41:123302
  • Verhaart RF, Fortunati V, Verduijn GM, van Walsum T, Veenland JF, Paulides MM. CT-based patient modeling for head and neck hyperthermia treatment planning: Manual versus automatic normal-tissue-segmentation. Radiother Oncol 2014;111:158–63
  • Verhaart RF, Rijnen Z, Fortunati V, Verduijn GM, van Walsum T, Veenland JF, et al. Temperature simulations in hyperthermia treatment planning of the head and neck region: Rigorous optimization of tissue properties. Strahlenther Onkol 2014;190:1117–24
  • Pichardo S, Kohler M, Lee J, Hynnyen K. In vivo optimisation study for multi-baseline MR-based thermometry in the context of hyperthermia using MR-guided high intensity focused ultrasound for head and neck applications. Int J Hyperthermia 2014;30:579–92
  • Rijnen Z, Bakker JF, Canters RA, Togni P, Verduijn GM, Levendag PC, et al. Clinical integration of software tool VEDO for adaptive and quantitative application of phased array hyperthermia in the head and neck. Int J Hyperthermia 2013;29:S181–93)

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