Human Corneal Basal Epithelial Cells Express an Embryonic Stem Cell Marker OCT4

REFERENCES

• Kenyon KR, Tseng SC. Limbal autograft transplantation for ocular surface disorders. Ophthalmology. 1989;96:709–722.
   PubMed Web of Science ®Google Scholar
• Cotsarelis G, Cheng S, Dong G, et al. Existence of slow cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelium stem cells. Cell. 1989;57:201–209.
   PubMed Web of Science ®Google Scholar
• Davanger M, Evensen A. Role of the pericorneal papillary structure in renewal of corneal epithelium. Nature. 1971;229:560–561.
   PubMed Web of Science ®Google Scholar
• Dua HS, Azuara-Blanco A. Limbal stem cells of the corneal epithelium. Surv Ophthalmol. 2000;44:415–425.
   PubMed Web of Science ®Google Scholar
• Chen Z, de Paiva CS, Luo L, et al. Characterization of putative limbal stem cell phenotype in human limbal epithelia. Stem Cells. 2004;22:355–366.
   PubMed Web of Science ®Google Scholar
• De Paiva CS, Chen Z, Corrales R, et al. ABCG2 transporter identifies a population of clonogenic human limbal epithelial cells. Stem Cells. 2005;23:63–73.
   PubMed Web of Science ®Google Scholar
• Schermer A, Galvin S, Sun TT. Differentiation related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol. 1986;103:49–62.
   PubMed Web of Science ®Google Scholar
• Matic M, Petrov I, Chen S, et al. Stem cells of the corneal epithelium lack connexins and metabolite transfer capacity. Differentiation. 1997;61:251–260.
   PubMed Web of Science ®Google Scholar
• Chen W, Hara K, Tian Q, et al. Existence of small slow-cycling Langerhans cells in the limbal basal epithelium that express ABCG2. Exp Eye Res. 2007;84:626–634.
   PubMed Web of Science ®Google Scholar
• Takeda J, Seino S, Bell GI. Human Oct-3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues. Nucleic Acids Res. 1992;20:4613–4620.
   PubMed Web of Science ®Google Scholar
• Pesce M, Schöler HR. Oct-4: Gatekeeper in the beginnings of mammalian development. Stem Cells. 2001;19:271–278.
   PubMed Web of Science ®Google Scholar
• Pesce M, Anastassiadis K, Schöler HR. Oct-4: Lessons of totipotency from embryonic stem cells. Tissues Organs. 1999;165:144–152.
   PubMed Web of Science ®Google Scholar
• Pesce M, Schöler HR. Oct-4: Control of totipotency and germline determination. Molec Reprod Devel. 2000;55:452–457.
   PubMed Web of Science ®Google Scholar
• Nichols J, Zevnik B, Anastassiadis K, et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct-4. Cell. 1998;95:379–391.
   PubMed Web of Science ®Google Scholar
• Okamoto K, Okazawa H, Okuda A, et al. A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell. 1990;60:461–472.
   PubMed Web of Science ®Google Scholar
• Rosner MH, Vigano MA, Ozato K, et al. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature. 1990;345:686–692.
   PubMed Web of Science ®Google Scholar
• Cheng L. Establishing a germ cell origin for metastatic tumors using OCT-4 immunohistochemistry. Cancer. 2004;101:2006–2010.
   PubMed Web of Science ®Google Scholar
• Monk M, Holding C. Human embryonic genes re-expressed in cancer cells. Oncogene. 2001;20,8085–8091.
   PubMed Web of Science ®Google Scholar
• Reubinoff BE, Pera MF, Fong CY, et al. Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro. Nat Biotechnol. 2000;18:399–404.
   PubMed Web of Science ®Google Scholar
• Niwa H, Miyazaki JI, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nature Genet. 2000;24:372–376
   PubMed Web of Science ®Google Scholar
• Hansis C, Grifo JA, Krey LC. Oct-4 expression in inner cell mass and trophectoderm of human blastocysts. Mol Hum Reprod. 2000;6:999–1004.
   PubMed Web of Science ®Google Scholar
• Boiani M, Eckardt S, Scholer HR, et al. Oct-4 distribution and level in mouse clones: Consequences for pluripotency. Genes Dev. 2002;16:1209–1219.
   PubMed Web of Science ®Google Scholar
• Tai MH, Chang CC, Kiupel M, et al. Oct-4 expression in adult human stem cells: Evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis. 2005;26:495–502.
   PubMed Web of Science ®Google Scholar
• Miki T, Lehmann T, Cai H, et al. Stem cell characteristics of amniotic epithelial cells. Stem Cells. 2005;23:1540–1559.
   Web of Science ®Google Scholar
• Abdel-Rahman B, Fiddler M, Rappolee D, et al. Expression of transcription regulating genes in human preimplantation embryos. Hum Reprod. 1995;10:2787–2792.
   PubMed Web of Science ®Google Scholar
• Suo GL, Han J, Wang X, et al. Oct-4 pseudogenes are transcribed in cancers. Biochem Biophys Res Commun. 2005;337:1047–1051.
   PubMed Web of Science ®Google Scholar
• Pellegrini G, Dellambra E, Golisano O, et al. P63 identifies keratinocyte stem cells. PNAS. 2001;98:3156–3161.
   PubMed Web of Science ®Google Scholar
• Palmieri SL, Peter W, Hess H, et al. Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev Biol. 1994;166:259–267.
   PubMed Web of Science ®Google Scholar
• Prusa AR, Marton E, Rosner M, et al. OCT-4-expressing cells in human amniotic fluid: A new source for stem cell research? Hum Reprod. 2003;18:1489–1493.
   PubMed Web of Science ®Google Scholar
• Verlinsky Y, Morozov G, Verlinsky O, et al. Isolation of cDNA libraries from individual human preimplantation embryos. Mol Hum Reprod. 1998;4:571–575.
   PubMed Web of Science ®Google Scholar
• Jin T, Branch DR, Zhang X, et al. Examination of POU homeobox gene expression in human breast cancer cells. Int J Cancer. 1999;81:104–112.
   PubMed Web of Science ®Google Scholar
• Looijenga LH, Stoop H, de Leeuw HP, et al. POU5F1 (OCT-3/4) identifies cells with pluripotent potential in human germ cell tumors. Cancer Res. 2003;63:2244–2250.
   PubMed Web of Science ®Google Scholar
• Steingart RA, Heldenberg E, Pinhasov A, et al. A vasoactive intestinal peptide receptor analog alters the expression of homeobox genes. Life Sci. 2002;71:2543–2552.
   PubMed Web of Science ®Google Scholar
• Gidekel S, Bergman Y. A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element. J Biol Chem. 2002;277:34521–34530.
   PubMed Web of Science ®Google Scholar
• Kimura H, Tada M, Nakatsuji N, et al. Histone code modifications on pluripotential nuclei of reprogrammed somatic cells. Mol Cell Biol. 2004;24:5710–5720.
   PubMed Web of Science ®Google Scholar
• Ben-Shushan E, Sharir H, Pikarsky E, et al. A dynamic balance between ARP-1/COUP-TFII, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol Cell Biol. 1995;15:1034–1048.
   PubMed Web of Science ®Google Scholar
• Monk M, Boubelik M, Lehnert S. Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development. 1987;99:371–382.
   PubMed Web of Science ®Google Scholar
• Byrne JA, Simonsson S, Western PS, et al. Nuclei of adult mammalian somatic cells are directly reprogrammed to Oct-4 stem cell gene expression by amphibian oocytes. Curr Biol. 2003;13:1206–1213.
   PubMed Web of Science ®Google Scholar