REFERENCES
- Abalain JH, Dossou H, Colin J, et al. Levels of collagen degradation products (telopeptides) in the tear film of patients with keratoconus. Cornea. 2000;19:474–476.
- Lane JD, Krumholz DM, Sack RA, et al. Tear glucose dynamics in diabetes mellitus. Curr Eye Res. 2006;31:895–901.
- Sack RA, Conradi L, Krumholz D, et al. Membrane array characterization of 80 chemokines, cytokines, and growth factors in open- and closed-eye tears: Angiogenin and other defense system constituents. Invest Ophthalmol Vis Sci. 2005;46:1228–1238.
- Carney FP, Morris CA, Willcox MD. Effect of hydrogel lens wear on the major tear proteins during extended wear. Australian & New Zealand J Ophthalmol. 1997;25 Suppl 1:S36–S38.
- Glasson MJ, Stapleton F, Keay L, et al. Differences in clinical parameters and tear film of tolerant and intolerant contact lens wearers. Invest Ophthalmol Vis Sci. 2003;44:5116–5124.
- Tan M, Thakur A, Morris C, et al. Presence of inflammatory mediators in the tears of contact lens wearers and non-contact lens wearers. Australian & New Zealand J Ophthalmol. 1997;25 Suppl 1:S27–S29.
- Thakur A, Willcox MDP. Contact lens wear alters the production of certain inflammatory mediators in tears. Exper Eye Res. 2000;70:255–259.
- Stapleton F, Willcox MD, Morris CA, et al. Tear changes in contact lens wearers following overnight eye closure. Curr Eye Res. 1998;17:183–188.
- Green-Church KB, Nichols KK, Kleinholz NM, et al. Investigation of the human tear film proteome using multiple proteomic approaches. Molec Vis. 2008;14:456–470.
- Li S, Sack R, Vijmasi T, et al. Antibody protein array analysis of the tear film cytokines. Optometry Vis Sci. 2008;85:653–660.
- Sakimoto T, Shoji J, Yamada A, et al. Upregulation of matrix metalloproteinases in tear fluid of patients with recurrent corneal erosion. Japan J Ophthalmol. 2007;51:343–346.
- van Setten GB, Stephens R, Tervo T, et al. Effects of the Schirmer test on the fibrinolytic system in the tear fluid. Exp Eye Res. 1990;50:135–141.
- van Haeringen NJ, Glasius E. The origin of some enzymes in tear fluid, determined by comparative investigation with two collection methods. Exp Eye Res. 1976;22:267–272.
- Choy CK, Cho P, Chung WY, et al. Water-soluble antioxidants in human tears: Effect of the collection method. Invest Ophthalmol Vis Sci. 2001;42:3130–3134.
- Sack R, Conradi L, Beaton A, et al. Antibody array characterization of inflammatory mediators in allergic and normal tears in the open and closed eye environments. Exper Eye Res. 2007;85:527–538.
- Fullard RJ, Tucker DL. Changes in human tear protein levels with progressively increasing stimulus. Invest Ophthalmol Vis Sci. 1991;32:2290–2301.
- Fukuda M, Fullard RJ, Willcox MD, et al. Fibronectin in the tear film. Invest Ophthalmol Vis Sci. 1996;37:459–467.
- Argueso P, Balaram M, Spurr-Michaud S, et al. Decreased levels of the goblet cell mucin MUC5AC in tears of patients with Sjogren syndrome. Invest Ophthalmol Vis Sci. 2002;43:1004–1011.
- Bjerrum KB, Prause JU. Collection and concentration of tear proteins studied by SDS gel electrophoresis. Presentation of a new method with special reference to dry eye patients. Graefes Arch Clin Exper Ophthalmol 1994;232:402–405.
- Caffery B, Joyce E, Boone A, et al. Tear lipocalin and lysozyme in Sjogren and non-Sjogren dry eye. Optometry Vis Sci. 2008;85:661–667.
- Ng V, Cho P, Mak S, et al. Variability of tear protein levels in normal young adults: Between-day variation. Graefes Arch Clin Exper Ophthalmol. 2000;238:892–899.
- Ng V, Cho P, Wong F, et al. Variability of tear protein levels in normal young adults: Diurnal (daytime) variation. Graefes Arch Clin Exper Ophthalmol. 2001;239:257–263.
- Smith VA, Khan-Lim D, Anderson L, et al. Does orally administered doxycycline reach the tear film? Br J Ophthalmol. 2008;92:856–859.
- Yasueda S-I Yamakawa, K, Nakanishi Y, et al. Decreased mucin concentrations in tear fluids of contact lens wearers. J Pharmaceut Biomed Anal. 2005;39:187–195.
- Smith VA, Hoh HB, Easty DL. Role of ocular matrix metalloproteinases in peripheral ulcerative keratitis. Br J Ophthalmol. 1999;83:1376–1383.
- Spurr-Michaud S, Argueso P, Gipson I. Assay of mucins in human tear fluid. Exper Eye Res. 2007;84:939–950.
- Van Haeringen NJ. Clinical biochemistry of tears. Survey Ophthalmol. 1981;26:84–96.
- Sack RA, Tan KO, Tan A. Diurnal tear cycle: Evidence for a nocturnal inflammatory constitutive tear fluid. Invest Ophthalmol Vis Sci. 1992;33:626–640.
- Laemmli UK. Cleavage of structural proteins during the assembly of the head of the bacteriophage. Nature. 1970;227:680–685.
- David NP, Darryl JCP, David MC, et al. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis. 1999;20:3551–3567.
- Keller A, Nesvizhskii AI, Kolker E, et al. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem. 2002;74:5383–5392.
- Nesvizhskii AI, Keller A, Kolker E, et al. A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem. 2003;75:4646–4658.
- Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement [see comment]. Lancet. 1986;1:307–310.
- Molloy MP, Bolis S, Herbert BR, et al. Establishment of the human reflex tear two-dimensional polyacrylamide gel electrophoresis reference map: New proteins of potential diagnostic value. Electrophoresis. 1997;18:2811–2815.
- Fullard RJ, Snyder C. Protein levels in nonstimulated and stimulated tears of normal human subjects. Invest Ophthalmol Vis Sci. 1990;31:1119–1126.
- Li D-Q Luo, L, Chen Z, et al. JNK and ERK MAP kinases mediate induction of IL-1[beta], TNF-[alpha] and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exper Eye Res. 2006;82:588–596.