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Original Article

Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid

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Pages 181-189 | Received 31 May 1994, Accepted 03 Nov 1994, Published online: 02 Jul 2009

References

  • Burton G. W., Ingold K. U. Vitamin E: Application of physical organic chemistry to the exploration of its structure and function. Acct. Chem. Res. 1986; 19: 194–204
  • Niki E. Antioxidants in relation to lipid peroxidation. Chem. Phys. Lipids 1987; 44: 227–236
  • Mukai K., Kageyama K. Y., Ishida T., Fukuda K. Synthesis and kinetic study of antioxidan activity of new tocopherol (vitamin E) compounds. J. Org. Chem. 1989; 54: 552–556
  • Niki E., Yamamoto Y., Takahashi M., Komuro E., Miyama Y. Inhibition of oxidation of biomembranes by α-tocopherol. Ann. N. Y. Acad. Sci. 1989; 570: 23–31
  • Barclay L. R. C., Bailey A. M. H., Kong D. The antioxidant activity of α-tocopherol-bovine serum albumin complex in micellar and liposome autoxidations. J. Biol. Chem. 1985; 260: 15809–15814
  • Anderson R. E., Maude M. B. Lipids of ocular tissues. Viii. The effects of essential fatty acid deficiency on the phospholipids of the photoreceptor membranesof rat retina. Arch. Biochem. Biophys. 1972; 151: 270–276
  • Kagan V. E., Shvedova A. A., Novikov K. N., Kozlov Y. P. Light-induced free radical oxidation of membrane lipids in photoreceptors of frog retina. Biochim. Biophys. Acta 1973; 330: 76–79
  • Aveldano M. I., Bazan N. G. Free fatty acids, diacyl-and triacylglycerols and total phospholipids in vertebrate retina: comparison with brain, choroid and plasma. J. Neurochem. 1974; 23: 1127–1135
  • Anderson R. E., Maude M. B., Zimmerman W. Lipids of tissues X. Lipid composition of subcellular fractions of bovine retina. Vision Res. 1975; 15: 1087–1090
  • Delmelle M. Generation of singlet oxygen by retinal. Photochem. Photobiol. 1978; 27: 731–734
  • Krasnovsky A. A., Kagan V. E. Generation and quenching of singlet oxygen by retinals. Proc. Natl. Acad. Sci. USSR 1978; 242: 229–232
  • Krasnovsky A. A., Kagan V. E. Photosensitized oxidation and quenching of singlet oxygen by pigments and lipids of photoreceptor cells of the retina. FEBS Lett. 1979; 108: 152–154
  • Stephens R. J., Negi D. S., Short S. M., van Kuijk F. J., Dratz E. A., Thomas D. W. Vitamin E distribution in ocular tissues following long-term dietary depletion and supplementation as determined by microdissection and gas-chromatography-mass spectrometry. Exp. Eye Res. 1988; 47: 237–245
  • Kagan V. E. Lipid Peroxidation in Biomembranes. CRC Press, Boca Raton 1988; 1–184
  • Hyes K. C. Retinal degeneration in monkeys induced by deficiencies of vitamin E or A. Invest. Ophthalmol. Vis Sci. 1974; 13: 499–510
  • Robison W. G., Kuwubara T., Bieri J. G. Deficiencies of vitamin E and A in the rat. Retinal damage and lipofuscin accumulation. Invest. Ophthalmol. Vis. Sci. 1980; 19: 1030–1037
  • Amemiya T. Effect of vitamin E administration on photoreceptor outer segment and retinal pigment epithelium of vitamin E deficient rats. Int. J. Wit. Nutr. Res. 1981; 51: 114–118
  • Goss-Sampson M. A., Muller D. R. P., Kriss A. Abnormalities of the electroretinogram and visual evoked potential in vitamin E deficient rats. Exp. Eye Res. 1991; 53: 623–627
  • Goss-Sampson M. A., Kriss A., Lindley K. J., Muller D. P. R. Vitamin E and retinal function. Free Radical Res. Commun. 1992; 16(S1)154
  • Muller D. P. R., Lloyd J. K., Wolff O. H. Vitamin E and neurological function. Lancet 1983; i: 225–227
  • Farnsworth C. C., Dratz E. A. Oxidative damage of retinal rod outer segment membranes and the role of vitamin E. Biochim. Biophys. Acta. 1976; 443: 556–570
  • Hunt D. F., Organisciak D. T., Wang H. M., Wu R. L. C. α-Tocopherol in the developing rat retina: a high pressure liquid chromatographic analysis. Curr. Eye Res. 1984; 3: 1281–1288
  • Vatassery G. T., Angerhofer C. K., Knox C. A., Deshmukh D. S. Concentrations of vitamin E in various neuroanatomical regions and subcellular fractions, and the uptake of vitamin E by specific areas of rat brain. Biochim. Biophys. Acta. 1984; 792: 118–122
  • Lang J., Gohil K., Packer L. Simultaneous determination of α-tocopherols, ubiquinols and ubiquinones in blood, plasma, tissue homogenates and subcellular fractions. Anal. Biochem. 1986; 157: 106–116
  • Lanero D. R. Therapeutic potential of vitamin E pathogenesis of spontaneous atherosclerosis. Free Radical Biol. Med. 1991; 11: 129–144
  • McPhail D. B., Nicol F., Arthur J. R., Goodman B. A. influence of dietary history production of free radicals in rat liver microsomes. Free Rad. Res. Comm. 1988; 4: 337–342
  • Cross C. E., Halliwell B., Borish E. T., Pryor W. A., Ames B. N., Saul R. L., McCord J. M., Harman D. Oxygen radicals and human disease. Ann. Int. Med. 1987; 107: 526–545
  • Halliwell B., Gutteridge J. M. C. Free Radicals in Biology and Medicine. Clarendon Press, Oxford 1989; 372–390
  • Takahashi M., Ikeda H., Sato E. E., Akimaru K., Edamatsu R., Inoue M., Utzumi K. Stimulus-specific enhancement of luminol chemiluminescence in neutrophils by phosphatidylserine liposomes. Arch. Biochem. Biophys. 1992; 298: 43–48
  • Machlin L. J. Vitamin E. Handbook of Vitamins: Nutritional, Biochemical and Clinical Aspects., L. J. Machlin. Marcel Dekker, NY 1984; 99–145
  • Young R. W. The renewal of photoreceptor cell outer segments. J. Cell Biol. 1967; 33: 61–72
  • Young R. W. The renewal of rod and cone outer segments in the rhesus monkey. J. Cell Biol. 1971; 49: 303–318
  • Bok D. Retinal photoreceptor-pigment epithelium interactions. Invest. Ophthalmol. Vis. Sci. 1985; 26: 1659–1694
  • Packer J. E., Slater T. R., Willson R. L. Direct observation of a free radical interaction vitamin E and vitamin C. Nature 1979; 278: 737–738
  • Scarpa M. A., Rigo M., Maiorino M., Ursini F., Gregolin C. Formation of α-tocopherol radical and recycling of α-tocopherol by ascorbate during peroxidation of phosphatidylcholine liposomes. Biochim. Biophys. Acta. 1984; 801: 215–219
  • Kagan V. E., Serbinova E. A., Packer L. Generation and recycling of radicals from phenolic antioxidants. Arch. Biochem. Biophys. 1990; 280: 33–39
  • Kagan V. E., Serbinova E. A., Forte T., Scita G., Packer L. Recycling of vitamin E in human low density lipoproteins. J. Lipid Res. 1992; 33: 385–397
  • Niki E., Tsuchiya J., Tanimura R., Kamiya Y. The regeneration of vitamin E from α-chromanoxyl radical by GSH and vitamin C. Chem. Lett. 1982; 6: 789–792
  • Wefers H., Sies H. The protection by ascorbate and GSH against microsomal lipid peroxidation is dependent on vitamin E. Eur. J. Biochem. 1988; 174: 533–537
  • Organisciak D. T., Wang H. M., Kou A. L. Rod outer segment lipid-opsin ratios in the developing normal and dystrophic rat. Exp. Eye Res. 1982; 34: 401–407
  • Stephens R. J., Negi D. S., Short S. M., van Kuijk R. J. G. M., Dratz E. A., Thomas D. W. Vitamin E distribution in ocular tissues following long-term dietary depletion and supplementation as determined by microdissection and gas chromatography-mass spectrometry. Exp. Eye Res. 1988; 47: 237–245
  • Organisciak D. T., Wang H. M., Kou A. L. Ascorbate and GSH levels in the developing normal and dystrophic rat retina: effect of intense light exposure. Curr. Eye Res. 1984; 3: 257–267
  • Winkler B. S., Giblin F. J. Gluthatione oxidation in retina: effects on biochemical and electrical activities. Exp. Eye. Res. 1983; 36: 287–297
  • Kagan V. E., Witt E., Goldman R., Scita G., Packer L. Ultraviolet light-induced generation of vitamin E radicals and their recycling. A possible photosensitizing effect of vitamin E in skin. Free Radical Res. Communs. 1992; 16: 51–64
  • Bowry V. W., Stocker R. Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein. J. Am. Chem. Soc 1993; 115: 6029–6044
  • Kannan R., Tang D., Mackic J. B., Zlokovic B. V., Fernandez-Checa J. C. A simple technique to determine GSH (GSH) levels and synthesis in ocular tissues as GSH-bimane adduct: application to normal and galactosemic guinea-pigs. Exp. Eye Res. 1993; 56: 45–50
  • Flohe L., Loschen G., Guntzler W. A., Eichele E. GSH peroxidase V; the kinetic mechanism. Hoppe-Seyler's. Z. Physiol. Chem. 1971; 353: 987–999
  • Winkler B. S. In vitro oxidation of ascorbic acid and its prevention by GSH. Biochim. Biophys. Acta 1987; 925: 258–264
  • Lam K. W., Wang L., Hong B. S., Treble D. Purification of phospholipid hydroperoxide GSH peroxidase from bovine retina. Current Eye Res. 1993; 12: 9–15
  • Loach P. A. Handbook of Biochemistry and Molecular Biology (3rd ed.), Physical and Chemical Data, Vol. I, G. D. Fasman. CRC Press. 1976; 123–130
  • Asmus K. D. Sulfur-centered free radicals. Methods in Enzymol. 1990; 186: 168–180
  • Altenkrich H., Stoltenbur-Didinger H., Wagner M., Herrman J., Walter G. Effects of lipoic acid in hexacarbon-induced neuropathy. Neurotoxicol. Teratol. 1990; 12: 619–622
  • Piering W. F., Bratanow N. Role of the clinical laboratory in guiding treatment of Amanita virosa mushroom poisoning: report of two cases. Clin Chem. 1990; 36: 571–574
  • Ramakrishnan N. W. W., Wolfe G. N. C. Radioprotection of hematopoietic tissues in mice by lipoic acid. Radiation Research. 1992; 130: 360–365
  • Katz M. L., Eldred G. E. Failure of vitamin E to protect the retina against damage resulting from bright cyclic light exposure. Invest. Ophthalmol. Vis. Sci. 1989; 30: 29–36
  • Katz M. L., Robison W. G. Light and aging effects on vitamin E in the retina and retinal pigment epithelium. Vision Res. 1987; 27: 1875–1879
  • Organisciak D. T., Wang H. M., Li Z. Y., Tso M. O. M. The ascorbate protective effect in retinal ligh damage. Invest. Ophthalmol. Vis. Sci. 1985; 26: 1580–1588
  • Organisciak D. T., Jiang Y. L., Wang H. M., Pickford M., Blanks J. C. Retinal light damage in rats exposed to intermittent light. Invest. Ophthalmol. Vis. Sci. 1989; 30: 795–805
  • Organisciak D. T., Jiang Y. L., Wang H. M., Bicknell I. The protective effect of ascorbic acid in retinal light damage of rats exposed to intermittent light. Invest. Ophthalmol. Vis. Sci. 1990; 31: 1195–1202

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