3,034
Views
76
CrossRef citations to date
0
Altmetric
Original Article

Heidelberg Ion Therapy Center (HIT): Initial clinical experience in the first 80 patients

, , , , , , , , , , , , , & show all
Pages 1132-1140 | Received 05 May 2010, Accepted 27 May 2010, Published online: 13 Sep 2010

References

  • Combs SE, Jakel O, Haberer T, Debus J. Particle therapy at the Heidelberg Ion Therapy Center (HIT) – Integrated research-driven university-hospital-based radiation oncology service in Heidelberg, Germany. Radiother Oncol 2010;95: 41–4.
  • Schulz-Ertner D, Didinger B, Nikoghosyan A, Jakel O, Zuna I, Wannenmacher M, . Optimization of radiation therapy for locally advanced adenoid cystic carcinomas with infiltration of the skull base using photon intensity-modulated radiation therapy (IMRT) and a carbon ion boost. Strahlenther Onkol 2003;179:345–51.
  • Schulz-Ertner D, Nikoghosyan A, Hof H, Didinger B, Combs SE, Jakel O, . Carbon ion radiotherapy of skull base chondrosarcomas. Int J Radiat Oncol Biol Phys 2007; 67:171–7.
  • Schulz-Ertner D, Karger CP, Feuerhake A, Nikoghosyan A, Combs SE, Jakel O, . Effectiveness of carbon ion radiotherapy in the treatment of skull-base chordomas. Int J Radiat Oncol Biol Phys 2007;68:449–57.
  • Combs SE, Nikoghosyan A, Jaekel O, Karger CP, Haberer T, Munter MW, . Carbon ion radiotherapy for pediatric patients and young adults treated for tumors of the skull base. Cancer 2009;115:1348–55.
  • Combs SE, Hartmann C, Nikoghosyan A, Jakel O, Karger CP, Haberer T, . Carbon ion radiation therapy for high-risk meningiomas. Radiother Oncol 2010;95:54–9.
  • Scholz M, Matsufuji N, Kanai T. Test of the local effect model using clinical data: Tumour control probability for lung tumours after treatment with carbon ion beams. Radiat Prot Dosimetry 2006;122:478–9.
  • Elsasser T, Kramer M, Scholz M. Accuracy of the local effect model for the prediction of biologic effects of carbon ion beams in vitro and in vivo. Int J Radiat Oncol Biol Phys 2008; 71:866–72.
  • Jakel O, Schulz-Ertner D, Debus J. Specifying carbon ion doses for radiotherapy: The Heidelberg approach. J Radiat Res (Tokyo) 2007;48(Suppl A):A87–95.
  • Kramer M, Jakel O, Haberer T, Rietzel E, Schardt D, Scholz M, . Treatment planning for scanned ion beams. Radiother Oncol 2004;73(Suppl 2):S80–5.
  • Jakel O, Debus J, Kramer M, Scholz M, Kraft G. Treatment planning for light ions: How to take into account relative biological effectiveness (RBE). Strahlenther Onkol 1999; 175(Suppl 2):12–4.
  • Haberer T, Debus J, Eickhoff H, Jakel O, Schulz-Ertner D, Weber U. The Heidelberg Ion Therapy Center. Radiother Oncol 2004;73(Suppl 2):S186–90.
  • Haberer T, Becher W, Schardt D, Kraft G. Magnetic scanning system for heavy ion therapy. Nucl Instrument Meth Phys Res 1993;A330:296–305.
  • Schulz-Ertner D, Karger CP, Feuerhake A, Nikoghosyan A, Combs SE, Jakel O, . Effectiveness of carbon ion radiotherapy in the treatment of skull-base chordomas. Int J Radiat Oncol Biol Phys 2007;68:449–57.
  • Suit H, Goldberg S, Niemierko A, Trofimov A, Adams J, Paganetti H, . Proton beams to replace photon beams in radical dose treatments. Acta Oncol 2003;42:800–8.
  • Suit H, Kooy H, Trofimov A, Farr J, Munzenrider J, DeLaney T, . Should positive phase III clinical trial data be required before proton beam therapy is more widely adopted? No. Radiother Oncol 2008;86:148–53.
  • Suit H, DeLaney T, Goldberg S, Paganetti H, Clasie B, Gerweck L, . Proton vs carbon ion beams in the definitive radiation treatment of cancer patients. Radiother Oncol 2010;95:3–22.
  • Pommier P, Lievens Y, Feschet F, Borras JM, Baron MH, Shtiliyanova A, . Simulating demand for innovative radiotherapies: An illustrative model based on carbon ion and proton radiotherapy. Radiother Oncol 2010.
  • Pijls-Johannesma M, van Mastrigt G, Hahn SM, De Ruysscher D, Baumert BG, Lammering G, . A systematic methodology review of phase I radiation dose escalation trials. Radiother Oncol 2010;95:135–41.
  • Peeters A, Grutters JP, Pijls-Johannesma M, Reimoser S, De Ruysscher D, Severens JL, . How costly is particle therapy? Cost analysis of external beam radiotherapy with carbon-ions, protons and photons. Radiother Oncol 2010;95: 45–53.
  • Pijls-Johannesma M, Grutters JP, Verhaegen F, Lambin P, De Ruysscher D. Do we have enough evidence to implement particle therapy as standard treatment in lung cancer? A systematic literature review. Oncologist 2010;15:93–103.
  • Schulz-Ertner D, Tsujii H. Particle radiation therapy using proton and heavier ion beams. J Clin Oncol 2007;25: 953–64.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.