The use of FDG-PET/CT and diffusion-weighted magnetic resonance imaging for response prediction before, during and after preoperative chemoradiotherapy for rectal cancer

References

• Kapiteijn E, Marijnen CA, Nagtegaal ID, Putter H, Steup WH, Wiggers T, . Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 2001;345:638–46.
   PubMed Web of Science ®Google Scholar
• Folkesson J, Birgisson H, Pahlman L, Cedermark B, Glimelius B, Gunnarsson U. Swedish Rectal Cancer Trial: Long lasting benefits from radiotherapy on survival and local recurrence rate. J Clin Oncol 2005;23:5644–50.
   PubMed Web of Science ®Google Scholar
• Bosset JF, Collette L, Calais G, Mineur L, Maingon P, Radosevic-Jelic L, . Chemotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med 2006;355:1114–23.
   PubMed Web of Science ®Google Scholar
• Valentini V, Coco C, Cellini N, Picciocchi A, Fares MC, Rosetto ME, . Ten years of preoperative chemoradiation for extraperitoneal T3 rectal cancer: Acute toxicity, tumor response, and sphincter preservation in three consecutive studies. Int J Radiat Oncol Biol Phys 2001;51:371–83.
   PubMed Web of Science ®Google Scholar
• Bosset JF, Calais G, Mineur L, Maingon P, Radosevic-Jelic L, Daban A, . Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: Preliminary results—EORTC 22921. J Clin Oncol 2005; 23:5620–7.
   PubMed Web of Science ®Google Scholar
• Capirci C, Rampin L, Erba PA, Galeotti F, Crepaldi G, Banti E, . Sequential FDG-PET/CT reliably predicts response of locally advanced rectal cancer to neo-adjuvant chemo-radiation therapy. Eur J Nucl Med Mol Imaging 2007;34: 1583–93.
   PubMed Web of Science ®Google Scholar
• Capirci C, Valentini V, Cionini L, De PA, Rodel C, Glynne-Jones R, . Prognostic value of pathologic complete response after neoadjuvant therapy in locally advanced rectal cancer: Long-term analysis of 566 ypCR patients. Int J Radiat Oncol Biol Phys 2008;72:99–107.
   PubMed Web of Science ®Google Scholar
• Vecchio FM, Valentini V, Minsky BD, Padula GD, Venkatraman ES, Balducci M, . The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer. Int J Radiat Oncol Biol Phys 2005;62:752–60.
   PubMed Web of Science ®Google Scholar
• Habr-Gama A, Perez RO, Nadalin W, Sabbaga J, Ribeiro U, Jr., Silva E Sousa AH Jr., . Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: Long-term results. Ann Surg 2004;240: 711–7.
   PubMed Web of Science ®Google Scholar
• Bujko K, Richter P, Kolodziejczyk M, Nowacki MP, Kulig J, Popiela T, . Preoperative radiotherapy and local excision of rectal cancer with immediate radical re-operation for poor responders. Radiother Oncol 2009;92:195–201.
   PubMed Web of Science ®Google Scholar
• Kim YH, Kim DY, Kim TH, Jung KH, Chang HJ, Jeong SY, . Usefulness of magnetic resonance volumetric evaluation in predicting response to preoperative concurrent chemoradiotherapy in patients with resectable rectal cancer. Int J Radiat Oncol Biol Phys 2005;62:761–8.
   PubMed Web of Science ®Google Scholar
• Denecke T, Rau B, Hoffmann KT, Hildebrandt B, Ruf J, Gutberlet M, . Comparison of CT, MRI and FDG-PET in response prediction of patients with locally advanced rectal cancer after multimodal preoperative therapy: Is there a benefit in using functional imaging? Eur Radiol 2005;15: 1658–66.
   PubMed Web of Science ®Google Scholar
• Roels S, Slagmolen P, Nuyts J, Lee JA, Loeckx D, Maes F, . Biological image-guided radiotherapy in rectal cancer: Is there a role for FMISO or FLT, next to FDG? Acta Oncol 2008;47:1237–48.
   PubMed Web of Science ®Google Scholar
• Janssen MH, Ollers MC, Riedl RG, van den Bogaard J, Buijsen J, van Stiphout RG, . Accurate prediction of pathological rectal tumor response after two weeks of preoperative radiochemotherapy using (18)F-Fluorodeoxyglucose-positron emission tomography-computed tomography imaging. Int J Radiat Oncol Biol Phys 2010;77:392–9.
   PubMed Web of Science ®Google Scholar
• Cascini GL, Avallone A, Delrio P, Guida C, Tatangelo F, Marone P, . 18F-FDG PET is an early predictor of pathologic tumor response to preoperative radiochemotherapy in locally advanced rectal cancer. J Nucl Med 2006;47: 1241–8.
   PubMed Web of Science ®Google Scholar
• Rosenberg R, Herrmann K, Gertler R, Kunzli B, Essler M, Lordick F, . The predictive value of metabolic response to preoperative radiochemotherapy in locally advanced rectal cancer measured by PET/CT. Int J Colorectal Dis 2009; 24:191–200.
   PubMed Web of Science ®Google Scholar
• Dzik-Jurasz A, Domenig C, George M, Wolber J, Padhani A, Brown G, . Diffusion MRI for prediction of response of rectal cancer to chemoradiation. Lancet 2002;360:307–8.
   PubMed Web of Science ®Google Scholar
• Sun YS, Zhang XP, Tang L, Ji JF, Gu J, Cai Y, . Locally advanced rectal carcinoma treated with preoperative chemotherapy and radiation therapy: Preliminary analysis of diffusion-weighted MR imaging for early detection of tumor histopathologic downstaging. Radiology 2010;254:170–8.
   PubMed Web of Science ®Google Scholar
• Hein PA, Kremser C, Judmaier W, Griebel J, Pfeiffer KP, Kreczy A, . Diffusion-weighted magnetic resonance imaging for monitoring diffusion changes in rectal carcinoma during combined, preoperative chemoradiation: Preliminary results of a prospective study. Eur J Radiol 2003;45:214–22.
   PubMed Web of Science ®Google Scholar
• Koh DM, Collins DJ. Diffusion-weighted MRI in the body: Applications and challenges in oncology. AJR Am J Roentgenol 2007;188:1622–35.
   PubMed Web of Science ®Google Scholar
• Chenevert TL, Stegman LD, Taylor JM, Robertson PL, Greenberg HS, Rehemtulla A, . Diffusion magnetic resonance imaging: An early surrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst 2000;92:2029–36.
   PubMedGoogle Scholar
• Vandecaveye V, Dirix P, De Keyzer F, Op de Beek K, Vander Poorten V, Roebben I, . Predictive value of diffusion-weighted magnetic resonance imaging during chemoradiotherapy for head and neck squamous cell carcinoma. Eur Radiol 2010.
   PubMed Web of Science ®Google Scholar
• Eccles C, Haider MA, Dawson LA. In reply to letter to the editor by Dr Willems et al. re: Eccles et al. Change in diffusion weighted MRI during liver cancer radiotherapy: Preliminary observations. Acta Oncol 2010;49:256–57.
   PubMed Web of Science ®Google Scholar
• Kremser C, Judmaier W, Hein P, Griebel J, Lukas P, de VA. Preliminary results on the influence of chemoradiation on apparent diffusion coefficients of primary rectal carcinoma measured by magnetic resonance imaging. Strahlenther Onkol 2003;179:641–9.
   PubMed Web of Science ®Google Scholar
• Comtat C, Kinahan P, Defrise M, Michel C, Townsend DW. Fast reconstruction of 3D PET data with accurate statistical modeling. IEEE Trans Nucl Sci 1998;45:1083–9.
   Web of Science ®Google Scholar
• Geets X, Lee JA, Bol A, Lonneux M, Gregoire V. A gradient-based method for segmenting FDG-PET images: Methodology and validation. Eur J Nucl Med Mol Imaging 2007;34:1427–38.
   PubMed Web of Science ®Google Scholar
• Beaulieu S, Kinahan P, Tseng J, Dunnwald LK, Schubert EK, Pham P, . SUV varies with time after injection in (18)F-FDG PET of breast cancer: Characterization and method to adjust for time differences. J Nucl Med 2003;44: 1044–50.
   PubMed Web of Science ®Google Scholar
• Sobin LH, Wittekind CH. International Union Against Cancer (UICC): TNM classification of malignant tumours. 6th. New York: Wiley; 2002.
   Google Scholar
• Janssen MH, Ollers MC, van Stiphout RG, Riedl RG, van den BJ, Buijsen J, . Blood glucose level normalization and accurate timing improves the accuracy of PET-based treatment response predictions in rectal cancer. Radiother Oncol 2010;95:203–8.
   PubMed Web of Science ®Google Scholar
• Habr-Gama A, Perez RO, Nadalin W, Nahas SC, Ribeiro U, Jr., Silva E Sousa AH Jr., . Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival. J Gastrointest Surg 2005; 9:901–9.
   Web of Science ®Google Scholar
• Rodel C, Martus P, Papadoupolos T, Fuzesi L, Klimpfinger M, Fietkau R, . Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer. J Clin Oncol 2005;23:8688–96.
   PubMed Web of Science ®Google Scholar
• Bujko K, Kolodziejczyk M, Nasierowska-Guttmejer A, Michalski W, Kepka L, Chmielik E, . Tumour regression grading in patients with residual rectal cancer after preoperative chemoradiation. Radiother Oncol 2010.
   Web of Science ®Google Scholar
• Mignanelli ED, Campos-Lobato LF, Stocchi L, Lavery IC, Dietz DW. Downstaging after chemoradiotherapy for locally advanced rectal cancer: Is there more (tumor) than meets the eye? Dis Colon Rectum 2010;53:251–6.
   PubMed Web of Science ®Google Scholar
• Majno G, Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995;146:3–15.
   PubMed Web of Science ®Google Scholar
• Gray LH, Conger AD, Ebert M, Hornsey S, Scott OC. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 1953;26: 638–48.
   PubMed Web of Science ®Google Scholar
• Leek RD, Landers RJ, Harris AL, Lewis CE. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br J Cancer 1999;79:991–5.
   PubMed Web of Science ®Google Scholar