Advancing our quantitative understanding of radiotherapy normal tissue morbidity

References

• Tucker SL, Liao Z, Dinh J, Bian SX, Mohan R, Martel MK, et al. Is there an impact of heart exposure on the incidence of radiation pneumonitis?Analysis of data from a large clinical cohort. Acta Oncol 2014;53:590–6.
   Google Scholar
• Beetz I, Steenbakkers RJ, Chouvalova O, Leemans CR, Doornaert P, van der Laan BF, et al. The QUANTEC criteria for parotid gland dose and their efficacy to prevent moderate to severe patient-rated xerostomia. Acta Oncol 2014;53:597–604.
   PubMed Web of Science ®Google Scholar
• Appelt AL, Vogelius IR, Farr KP, Khalil AA, Bentzen SM. Towards individualized dose constraints: Adjusting the QUANTEC radiation pneumonitis model for clinical risk factors. Acta Oncol 2014;53:605–12.
   PubMed Web of Science ®Google Scholar
• Cella L, Liuzzi R, D’Avino V, Conson M, Di Biase A, Picardi M, et al. Pulmonary damage in Hodgkin’s lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury. Acta Oncol 2014;53: 613–9.
   PubMed Web of Science ®Google Scholar
• Johansen S, Fosså K, Nesvold IL, Malinen E, Fosså SD. Arm and shoulder morbidity following surgery and radiotherapy for breast cancer. Acta Oncol 2014;53:521–9.
   PubMed Web of Science ®Google Scholar
• Lindblom U, Garskog O, Kjellen E, Laurell G, Jaghagen EL, Wahlberg P, et al. Radiation-induced trismus in the ARTSCAN head and neck trial. Acta Oncol 2014;53:620–7.
   PubMed Web of Science ®Google Scholar
• Chow TL, Louie AV, Palma DA, D’Souza DP, Perera F, Rodrigues GB, et al. Radiation-induced lung injury after concurrent neoadjuvant chemoradiotherapy for locally advanced breast cancer. Acta Oncol 2014;53:697–701.
   PubMed Web of Science ®Google Scholar
• Huang EX, Hope AJ, Lindsay PE, Trovo M, El Naqa I, Deasy JO, et al. Heart irradiation as a risk factor for radiation pneumonitis. Acta Oncol 2011;50:51–60.
   PubMed Web of Science ®Google Scholar
• Deasy J, Robinson C, Huang E, Molotievschi A, Bradley J. Independent test of a model to predict radiation pneumonitis after definitive radiation therapy for locally advanced non-small cell lung cancer: Heart irradiation is (again) a statistically significant risk factor (abstr). Int J Radiat Oncol Biol Phys 2012;84(Suppl 1):S32.
   Google Scholar
• Novakova-Jiresova A, van Luijk P, van Goor H, Kampinga HH, Coppes RP. Pulmonary radiation injury: Identification of risk factors associated with regional hypersensitivity. Cancer Res 2005;65:3568–76.
   PubMed Web of Science ®Google Scholar
• van Luijk P, Novakova-Jiresova A, Faber H, Schippers JM, Kampinga HH, Meertens H, et al. Radiation damage to the heart enhances early radiation-induced lung function loss. Cancer Res 2005;65:6509–11.
   PubMed Web of Science ®Google Scholar
• van Luijk P, Faber H, Meertens H, Schippers JM, Langendijk JA, Brandenburg S, et al. The impact of heart irradiation on dose-volume effects in the rat lung. Int J Radiat Oncol Biol Phys 2007;69:552–9.
   PubMed Web of Science ®Google Scholar
• Ghobadi G, van der Veen S, Bartelds B, de Boer RA, Dickinson MG, de Jong JR, et al. Physiological interaction of heart and lung in thoracic irradiation. Int J Radiat Oncol Biol Phys 2012;84:e639–46.
   PubMed Web of Science ®Google Scholar
• Deasy JO, Moiseenko V, Marks L, Chao KS, Nam J, Eisbruch A. Radiotherapy dose-volume effects on salivary gland function. Int J Radiat Oncol Biol Phys 2010;76(Suppl 3): S58–63.
   PubMed Web of Science ®Google Scholar
• Deasy JO, Bentzen SM, Jackson A, Ten Haken RK, Yorke ED, Constine LS, et al. Improving normal tissue complication probability models: The need to adopt a “data-pooling” culture. Int J Radiat Oncol Biol Phys 2010;76(Suppl 3): S151–4.
   PubMed Web of Science ®Google Scholar
• Roelofs E, Persoon L, Nijsten S, Wiessler W, Dekker A, Lambin P. Benefits of a clinical data warehouse with data mining tools to collect data for a radiotherapy trial. Radiother Oncol 2013;108:174–9.
   PubMed Web of Science ®Google Scholar
• Roelofs E, Dekker A, Meldolesi E, van Stiphout RG, Valentini V, Lambin P. International data-sharing for radiotherapy research: An open-source based infrastructure for multicentric clinical data mining. Radiother Oncol 2014;110:370–4.
   PubMed Web of Science ®Google Scholar
• Mutter RW, Liu F, Abreu A, Yorke E, Jackson A, Rosenzweig KE. Dose-volume parameters predict for the development of chest wall pain after stereotactic body radiation for lung cancer. Int J Radiat Oncol Biol Phys 2012; 82:1783–90.
   PubMed Web of Science ®Google Scholar
• Bentzen SM, Constine LS, Deasy JO, Eisbruch A, Jackson A, Marks LB, et al. Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): An introduction to the scientific issues. Int J Radiat Oncol Biol Phys 2010;76(Suppl 3):S3–9.
   PubMed Web of Science ®Google Scholar
• Marks LB, Yorke ED, Jackson A, Ten Haken RK, Constine LS, Eisbruch A, et al. Use of normal tissue complication probability models in the clinic. Int J Radiat Oncol Biol Phys 2010;76(Suppl 3):S10–9.
   PubMed Web of Science ®Google Scholar
• Jackson A, Marks LB, Bentzen SM, Eisbruch A, Yorke ED, Ten Haken RK, et al. The lessons of QUANTEC: Recommendations for reporting and gathering data on dose-volume dependencies of treatment outcome. Int J Radiat Oncol Biol Phys 2010;76(Suppl 3):S155–60.
   PubMed Web of Science ®Google Scholar
• Liu M, Moiseenko V, Agranovich A, Karvat A, Kwan W, Saleh ZH, et al. Normal Tissue Complication Probability (NTCP) modeling of late rectal bleeding following external beam radiotherapy for prostate cancer: A test of the QUANTEC-recommended NTCP model. Acta Oncol 2010;49:1040–4.
   PubMed Web of Science ®Google Scholar
• Trott KR, Doerr W, Facoetti A, Hopewell J, Langendijk J, van Luijk P, et al. Biological mechanisms of normal tissue damage: Importance for the design of NTCP models. Radiother Oncol 2012;105:79–85.
   PubMed Web of Science ®Google Scholar
• Mukesh M, Harris E, Jena R, Evans P, Coles C. Relationship between irradiated breast volume and late normal tissue complications: A systematic review. Radiother Oncol 2012;104:1–10.
   PubMed Web of Science ®Google Scholar
• Vogelius IR, Bentzen SM. A literature-based meta-analysis of clinical risk factors for development of radiation induced pneumonitis. Acta Oncol 2012;51:975–83.
   PubMed Web of Science ®Google Scholar
• Lee TF, Fang FM. Quantitative analysis of normal tissue effects in the clinic (QUANTEC) guideline validation using quality of life questionnaire datasets for parotid gland constraints to avoid causing xerostomia during head-and-neck radiotherapy. Radiother Oncol 2013;106: 352–8.
   PubMed Web of Science ®Google Scholar
• Ravn S, Holmberg M, Sørensen P, Frøkjær JB, Carl J. Differences in supratentorial white matter diffusion after radiotherapy – new biomarker of normal brain tissue damage?Acta Oncol 2013;52:1314–9.
   PubMed Web of Science ®Google Scholar
• De Ruysscher D, Sharifi H, Defraene G, Kerns SL, Christiaens M, De Ruyck K, et al. Quantification of radiation-induced lung damage with CT scans: The possible benefit for radiogenomics. Acta Oncol 2013;52:1405–10.
   PubMed Web of Science ®Google Scholar
• Thor M, Apte A, Deasy JO, Karlsdóttir À, Moiseenko V, Liu M, et al. Dose/volume-response relations for rectal morbidity using planned and simulated motion-inclusive dose distributions. Radiother Oncol 2013;109:388–93.
   PubMed Web of Science ®Google Scholar
• Stenmark MH, Conlon AS, Johnson S, Daignault S, Litzenberg D, Marsh R, et al. Dose to the inferior rectum is strongly associated with patient reported bowel quality of life after radiation therapy for prostate cancer.Radiother Oncol 2014;110:291–7.
   PubMed Web of Science ®Google Scholar
• Peeters ST, Lebesque JV, Heemsbergen WD, van Putten WL, Slot A, Dielwart MF, et al. Localized volume effects for late rectal and anal toxicity after radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 2006;64:1151–61.
   PubMed Web of Science ®Google Scholar
• Heemsbergen WD, Al-Mamgani A, Witte MG, van Herk M, Pos FJ, Lebesque JV. Urinary obstruction in prostate cancer patients from the Dutch trial (68 Gy vs. 78 Gy): Relationships with local dose, acute effects, and baseline characteristics. Int J Radiat Oncol Biol Phys 2010;78:19–25.
   PubMed Web of Science ®Google Scholar
• Liang Y, Messer K, Rose BS, Lewis JH, Jiang SB, Yashar CM, et al. Impact of bone marrow radiation dose on acute hematologic toxicity in cervical cancer: Principal component analysis on high dimensional data. Int J Radiat Oncol Biol Phys 2010;78:912–9.
   PubMed Web of Science ®Google Scholar