522
Views
4
CrossRef citations to date
0
Altmetric
Original Article

Poly(ADP-ribose) polymerase inhibition improves endothelin-1-induced endothelial dysfunction in rat thoracic aorta

, , , &
Pages 215-222 | Received 03 Feb 2014, Accepted 21 Mar 2014, Published online: 16 Jun 2014

References

  • Perticone F, Sciacqua A, Maio R, Perticone M, Maas R, Boger RH, et al. Asymmetric dimethylarginine, l-arginine, and endothelial dysfunction in essential hypertension. J Am Coll Cardiol. 2005;46:518–23.
  • De Vriese AS, Verbeuren TJ, Van de Voorde J, Lameire NH, Vanhoutte PM. Endothelial dysfunction in diabetes. Br J Pharmacol. 2000;130:963–74.
  • Treasure CB, Vita JA, Cox DA, Fish RD, Gordon JB, Mudge GH, et al. Endothelial-dependent dilation of the coronary microvasculature is impaired in dilated cardiomyopathy. Circulation. 1990;91:772–9.
  • Poredos P. Endothelial dysfunction and cardiovascular disease. Pathophysiol Haemost Thromb. 2002;32:274–7.
  • Böhm F, Pernow J. The importance of endothelin-1 for vascular dysfunction in cardiovascular disease. Cardiovasc Res. 2007;76:8–18.
  • Münzel T, Just H, Harrison DG. The physiology and pathophysiology of the nitric oxide/superoxide system. In Born GVR, Schwartz CJ, editors. Vascular endothelium: physiology, pathology and therapeutic options. Stuttgart: Schattauer; 1997. p 205–20.
  • Li L, Fink GD, Watts SW, Northcott CA, Galligan JJ, Pagano PJ, et al. Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation. 2003;107:1053–8.
  • Gómez-Guzmán M, Jiménez R, Sánchez M, Zarzuelo MJ, Galindo P, Quintela AM, et al. Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension. Free Radic Biol Med. 2012;52:70–9.
  • Jiménez R, López-Sepúlveda R, Kadmiri M, Romero M, Vera R, Sánchez M, et al. Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase. Free Radic Biol Med. 2007;43:462–73.
  • Radovits T, Lin LN, Zotkina J, Gero D, Szabó C, Karck M, et al. Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro. Eur J Pharmacol. 2007;564:158–66.
  • Celik-Ozenci C, Tasatargil A, Tekcan M, Sati L, Gungor E, Isbir M, et al. Effects of abamectin exposure on male fertility in rats: potential role of oxidative stress-mediated poly(ADP-ribose) polymerase (PARP) activation. Regul Toxicol Pharmacol. 2011;61:310–17.
  • Tekcan M, Koksal IT, Tasatargil A, Kutlu O, Gungor E, Celik-Ozenci C. Potential role of poly(ADP-ribose) polymerase activation in the pathogenesis of experimental left varicocele. J Androl. 2012;33:122–32.
  • Tasatargil A, Dalaklioglu S, Sadan G. Poly(ADP-ribose) polymerase inhibition prevents homocysteine-induced endothelial dysfunction in the isolated rat aorta. Pharmacology. 2004;72:99–105.
  • McDonald MC, Mota-Filipe H, Wright JA, Abdelrahman M, Threadgill MD, Thompson AS, et al. Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly(ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock. Br J Pharmacol. 2000;130:843–50.
  • Spina-Purrello V, Patti D, Giuffrida-Stella AM, Nicoletti VG. Parp and cell death or protection in rat primary astroglial cell cultures under LPS/IFNgamma induced proinflammatory conditions. Neurochem Res. 2008;33:2583–92.
  • Drummond GR, Selemidis S, Griendling KK, Sobey CG. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov. 2011;10:453–71.
  • Takac I, Schröder K, Brandes RP. The Nox family of NADPH oxidases: friend or foe of the vascular system? Curr Hypertens Rep. 2012;14:70–8.
  • Homburg S, Visochek L, Moran N, Dantzer F, Priel E, Asculai E, et al. A fast signal-induced activation of poly(ADP-ribose) polymerase: a novel downstream target of phospholipase c. J Cell Biol. 2000;150:293–307.
  • Berger NA. Poly(ADP-ribose) in the cellular response to DNA damage. Radiat Res. 1985;101:4–15.
  • Schraufstatter IU, Hinshaw DB, Hyslop PA, Spragg RG, Cochrane CG. Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide. J Clin Invest. 1986;77:1312–20.
  • Sallmann FR, Bourassa S, Saint-Cyr J, Poirier GG. Characterization of antibodies specific for the caspase cleavage site on poly(ADP-ribose) polymerase: specific detection of apoptotic fragments and mapping of the necrotic fragments of poly(ADP-ribose) polymerase. Biochem Cell Biol. 1997;75:451–6.