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Articles

Failure of oral DHEA treatment to increase local salivary androgen outputs of female patients with Sjögren's syndrome

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Pages 387-390 | Accepted 07 Apr 2011, Published online: 31 Aug 2011

References

  • Vitali CS, Bombardierdi R, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American–European Consensus Group. Ann Rheum Dis 2002;61:554–8.
  • Valtysdottir ST, Wide L, Hallgren R. Low serum dehydroepiandrosterone sulphate in women with primary Sjögren's syndrome as an isolated sign of impaired HPA axis function. J Rheumatol 2001;28:1259–65.
  • Laine M, Porola P, Udby L, Kjeldsen L, Cowland JB, Borregaard N, Low salivary DHEA and androgen-regulated CRISP-3 in Sjögren's syndrome. Arthritis Rheum 2007;56:2575–84.
  • Porola P, Virkki L, Przybyla BD, Laine M, Patterson TA, Pihakari A, Androgen deficiency and defective intracrine processing of dehydroepiandrosterone in salivary glands in Sjögren's syndrome. J Rheumatol 2008;35:2229–35.
  • Spaan M, Porola P, Laine M, Rozman B, Azuma M, Konttinen YT. Healthy human salivary glands contain a DHEA-S processing intracrine machinery, which is deranged in primary Sjögren's syndrome. J Cell Mol Med 2009;13:1261–70.
  • Forsblad d'Elia H, Carlsten H, Labrie F, Konttinen YT, Ohlsson C. Low serum levels of sex-steroids are associated with disease characteristics in primary Sjogren's syndrome; supplementation with dehydroepiandrosterone restores the concentrations. J Clin Endocrinol Metab 2009;94:2044–51.
  • Virkki LM, Porola P, Forsblad-d'Elia H, Valtysdottir S, Solovieva SA, Konttinen YT. Dehydroepiandrosterone (DHEA) substitution treatment in severe fatigue in DHEA-deficient patients with primary Sjögren's syndrome. Arthritis Care Res (Hoboken) 2010;62:118–24.
  • Hammes A, Andreassen TK, Spoelgen R, Raila J, Hubner N, Schulz H, Role of endocytosis in cellular uptake of sex steroids. Cell 2005;122:751–62.
  • Morales AJ, Nolan JJ, Nelson JC, Yen SS. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab 1994;78:1360–7.
  • van Niekerk JK, Huppert FA, Herbert J. Salivary cortisol and DHEA: association with measures of cognition and well-being in normal older men, and effects of three months of DHEA supplementation. Psychoneuroendocrinology 2001;26:591–612.
  • Alhaj HA, Massey AE, McAllister-Williams RH. Effects of DHEA administration on episodic memory, cortisol and mood in healthy young men: a double-blind, placebo-controlled study. Psychopharmacology (Berl) 2006;188:541–51.
  • Swinkels LM, Meulenberg PM, Ross HA, Benraad TJ. Salivary and plasma free testosterone and androstenedione levels in women using oral contraceptives containing desogestrel or levonorgestrel. Ann Clin Biochem 1988;25:354–9.
  • Granger DA, Schwartz EB, Booth A, Curran M, Zakaria D. Assessing dehydroepiandrosterone in saliva: a simple radioimmunoassay for use in studies of children, adolescents and adults. Psychoneuroendocrinology 1999;24:567–79.
  • Ahn RS, Lee YJ, Choi JY, Kwon HB, Chun SI. Salivary cortisol and DHEA levels in the Korean population: age-related differences, diurnal rhythm, and correlations with serum levels. Yonsei Med J 2007;30:48:379–88.
  • Labrie F, Luu-The V, Belanger A, Lin SX, Simard J, Pelletier G, Is dehydroepiandrosterone a hormone? J Endocrinol 2005;187:169–96.

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