The T and B Cell Repertoire of Patients with Rheumatoid Arthritis

References

• Burnet FM. The clonal selection theory of acquired immunity. Cambridge University Press, London 1959
   Google Scholar
• Wen L, Hanvanich M, Werner-Favre Ch, Brouwers M, Penin L H, Zubler RH. Limiting dilution assay for human B cells based on their activation by mutant EL4 thymoma cells: total and anti-malaria responder cell frequencies. Eur J Immunol 1987; 17: 887–92
   PubMed Web of Science ®Google Scholar
• Schwab J, Lukowsky A, Volk H-D, Peter H H, Melchers I. Precursor frequencies for DNA-specific B lymphocytes in patients with systemic lupus erythematosus (SLE). Clin Exp Immunol 1994; 96: 450–7
   PubMed Web of Science ®Google Scholar
• Lefkovits I, Waldmann H. Limiting dilution analysis of cells in the immune system. Cambridge University press., Cambridge 1979
   Google Scholar
• Klareskog L, Olsson T. Autoimmunity to collagen II and myelin basic protein: Comparative studies in humans and rodents. Immunol Rev 1990; 118: 285–310
   PubMed Web of Science ®Google Scholar
• Cohen IR. Autoimmunity to chaperonins in the pathogen-esis of arthritis and diabetes. Ann Rev Immunol 1991; 9: 567–89
   PubMed Web of Science ®Google Scholar
• Rudolphi U, Hohlbaum A, Lang B, Peter H H, Melchers I. The B cell repertoire of patients with rheumatoid arthritis Frequencies and specificities of peripheral blood B cells reacting with human IgG, human collagens, a mycobac-terial heat shock protein and other antigens. Clin Exp Immunol 1993; 92: 404–11
   PubMed Web of Science ®Google Scholar
• Heat shock proteins and immune response. Current topics in microbiology and immunology. Springer., Berlin 1991
   Google Scholar
• Shin E K, Matsuda F, Ozaki S, Kumagai S, Olerup O, Ström H, et al. Polymorphism of the Human Im-munoglobulin Variable Region Segment V1–4.1. Im-munogenetics 1993; 38: 304–6
   PubMed Web of Science ®Google Scholar
• Roether E, Schaefer H E, Schlesier M, Peter HH. Felty-Syndrom. Klinische Immunologie, H H Peter. Urban & Schwarzenberg., München-Wien-Baltimore 1991; 160
   Google Scholar
• Saizawa K M, Melchers I, Eichmann K. Genetic control of B cell function. III. IgVH controlled polymorphism in the frequencies of B cells that recognize xenogeneic red blood cells. Eur J Immunol 1984; 15: 124
   Web of Science ®Google Scholar
• Stasny P. Association of the B-cell alloantigen DR4w4 with rheumatoid arthritis. N Engl J Med 1978; 298: 869–71
   PubMed Web of Science ®Google Scholar
• Wallin J, Hillert J, Olerup O, Carlsson B, Ström H. Association of rheumatoid arthritis with a dominant DR1/DR4/Dw14 sequence motif, but not with T cell receptor β chain gene alleles or haplotypes. Arthrtitis Rheum 1991; 34: 1415–23
   Google Scholar
• Weyand C M, Xie C, Goronzy JJ. Homozygosity for the HLA-DRB1 allele selects for extra-articular manifestations in rheumatois arthritis. J Clin Invest 1992; 89: 2033–9
   PubMed Web of Science ®Google Scholar
• Winchester R, Dwyer E, Rose S. The genetic basis of rheumatoid arthritis: the shared epitope hypothesis. Rheumatic Disease Clinics of North America 1992; 18: 761–83
   PubMed Web of Science ®Google Scholar
• Goronzy J J, Weyand CM. Interplay of T lymphocytes and HLA-DR molecules in rheumatoid arthritis. Curr in Rheumatol 1993; 5: 169–77
   PubMedGoogle Scholar
• Ziff M. Role of endothelium in chronic inflammatory synovitis. Arthritis Rheum 1991; 34: 1345–52
   PubMed Web of Science ®Google Scholar
• Panayi G S, Lanchbury J S, Kingsley GH. The importance of the T cell in initiatiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992; 35: 729–35
   PubMed Web of Science ®Google Scholar
• Firestein G S, Zvaifler NJ. How important are T cells in chronic rheumatoid synovitis. Arthritis Rheum 1990; 33: 768–73
   PubMed Web of Science ®Google Scholar
• Haqqi T M, Anderson G D, Banerjee TI, David CS. Restricted heterogeneity in T-cell antigen receptor V beta gene usage in the lymph nodes and arthritic joints of mice. Proc Natl Acad Sci USA 1992; 89: 1253–5
   PubMed Web of Science ®Google Scholar
• Griffiths M M, Cole B C, Ito J, Harper D S, Anderson G D, Cannon G W, et al. T-cell receptors and collagen induced arthritis in H-2r mice. Autoimmunity 1993; 14: 221–9
   PubMed Web of Science ®Google Scholar
• Osman G E, Toda M, Kanagawa O, Hood LE. Characterization of the T cell receptor repertoire causing collagen arthritis in mice. J Exp Med 1993; 177: 387–95
   PubMed Web of Science ®Google Scholar
• Palliard X, West S G, Lafferty J A, Clements J R, Kappler J W, Marrack P, et al. Evidence for the effects of a super-antigen in rheumatoid arthritis. Science 1991; 253: 325–9
   PubMed Web of Science ®Google Scholar
• Howell M D, Diveley J P, Lundeen K A, Esty A, Winsters S T, Carlo D J, et al. Limited T-cell receptor b-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis. Proc Natl Acad Sci USA 1991; 88: 10921–5
   PubMed Web of Science ®Google Scholar
• Williams W V, Fang Q, Demarco D, VonFeldt J, Zurier R B, Weiner DB. Restricted heterogeneity of T cell receptor transcripts in rheumatoid synovium. J Clin Invest 1992; 90: 326–33
   PubMed Web of Science ®Google Scholar
• Lu Y, Kim B S, Pope RM. Clonal heterogeneity of synovial fluid T lymphocytes in inflammatory synovitis. Clin Immunol Immunopathol 1992; 63: 28–33
   PubMedGoogle Scholar
• Van Laar J M, Miltenburg A M, Verdonk M J, Daha M R, de Vries R R, Van den Elsen P I, et al. T-cell receptor beta-chain gene rearrangements of T-cell populations expanded from multiple sites of synovial tissue obtained from a patient with rheumatoid arthritis. Scand J Immunol 1992; 35: 187–94
   PubMed Web of Science ®Google Scholar
• Bucht A, Oksenberg J R, Lindblad S, Gronberg A, Stein-Man L, Klareskog L. Characterization of T-cell receptor alpha beta repertoire in synovial tissue from different temporal phases of rheumatoid arthritis. Scand J Immunol 1992; 35: 159–65
   PubMed Web of Science ®Google Scholar
• Richardson BC. T cell receptor usage in rheumatic disease. Clin Exp Rheumatol 1992; 10: 271–83
   PubMed Web of Science ®Google Scholar
• Sottini A, Imberti L, Gorla R, Catteneo R, Primi D. Restricted expression of T cell receptor Vβ but not Vα genes in rheumatoid arthritis. Eur J Immunol 1991; 21: 461–6
   PubMed Web of Science ®Google Scholar
• Pluschke G, Riken G, Taube H, Kroninger H, Melchers I, Peter H H, Eichmann K, Krawinkel U. Biased T-cell receptor V alpha region repertoire in the synovial fluid of rheumatoid arthritis patients. Eur J Immunol 1991; 21: 2749–54
   PubMed Web of Science ®Google Scholar
• Wilson K B, Quayle A J, Suleyman S, Kjeldsen Kragh J, Forre O, Natvig J B, Capra ID. Heterogeneity of the TCR repertoire in synovial fluid T lymphocytes responding to BCG in a patient with early rheumatoid arthritis. Scand J Immunol 1993; 38: 102–12
   PubMed Web of Science ®Google Scholar
• Williams W V, Kieber Emmons T, Fang Q, Von Feldt J, Wang B, Ramanujam T, et al. Conserved motifs in rheumatoid arthritis synovial tissue T-cell receptor beta chains. DNA Cell Biol 1993; 12: 425–34
   PubMed Web of Science ®Google Scholar
• Dedeoglu F, Kaymaz H, Seaver N, Schluter S F, Yocum D E, Marchalonis JJ. Lack of preferential V beta usage in synovial T cells of rheumatoid arthritis patients. Immunol Res 1993; 12: 12–20
   PubMed Web of Science ®Google Scholar
• Davey M P, Munkirs DD. Patterns of T-cell receptor variable beta gene expression by synovial fluid and peripheral blood T-cells in rheumatoid arthritis. Clin Immunol Immunopathol 1993; 68: 79–87
   PubMedGoogle Scholar
• Korthauer U, Hennerkes B, Menninger H, Mages H W, Zacher J, Potocnik A J, et al. Oligoclonal T cells in rheumatoid arthritis: identification strategy and molecular characterization of a clonal T-cell receptor. Scand J Immunol 1992; 36: 855–63
   PubMed Web of Science ®Google Scholar
• Gudmundsson S, Ronnelid J, Karlsson Parra A, Lysholm J, Gudbjornsson B, Widenfalk B, et al. T-cell receptor V-gene usage in synovial fluid and synovial tissue from RA patients. Scand J Immunol 1992; 36: 681–8
   PubMed Web of Science ®Google Scholar
• De Keyser F, Verbruggen G, Veys E M, Cuvelier C, Mal-Fait A M, Benoit D, et al. T cell receptor V beta usage in rheumatoid nodules: marked oligoclonality among IL-2 expanded lymphocytes. Clin Immunol Immunopathol 1993; 68: 29–34
   PubMedGoogle Scholar
• DerSimonian H, Sugita M, Glass D N, Maier A L, Wein-Blatt M E, Reme T, Brenner MB. Clonal V alpha 12.1+ T cell expansions in the peripheral blood of rheumatoid arthritis patients. J Exp Med 1993; 177: 1623–31
   PubMed Web of Science ®Google Scholar
• Sottini A, Imberti L, Bettinardi A, Mazza C, Gorla R, Primi D. Selection of T lymphocytes in two rheumatoid arthritis patients defines different T-cell receptor V beta repertoires in CD4+ and CD8+ T-cell subsets. J Autoim-mun 1993; 6: 621–37
   PubMed Web of Science ®Google Scholar
• Bucht A, Soderstrom K, Hultman T, Uhlen M, Nilsson E, Kiessling R, Gronberg A. T cell receptor diversity and activation markers in the V delta 1 subset of rheumatoid synovial fluid and peripheral blood T lymphocytes. Eur J Immunol 1992; 22: 567–74
   PubMed Web of Science ®Google Scholar
• Doherty P J, Yang S X, Laxer R M, Silverman E D, Inman R, Pan S. Evidence for clonal expansion of T cell receptor V gamma II+ T cells in the synovial fluid of patients with arthritis. J Immunol 1992; 149: 295–9
   PubMed Web of Science ®Google Scholar
• Olive C, Gatenby P A, Serjeantson SW. Variable gene usage of T cell receptor gamma- and delta-chain transcripts expressed in synovia and peripheral blood of patients with rheumatoid arthritis. Clin Exp Immunol 1992; 87: 172–7
   PubMed Web of Science ®Google Scholar
• Meliconi R, Uguccioni M, D'Errico A, Cassisa A, Frizziero L, Facchini A. T-cell receptor gamma-delta positive lymphocytes in synovial membrane. Br J Rheumatol 1992; 31: 59–61
   PubMedGoogle Scholar
• Kohsaka H, Chen P P, Taniguchi A, Ollier W E, Carson DA. Divergent T cell receptor gamma repertoires in rheumatoid arthritis monozygotic twins. Arthritis Rheum 1993; 36: 213–21
   PubMedGoogle Scholar
• Olive C, Gatenby P A, Serjeantson SW. Molecular characterization of the V gamma 9 T cell receptor repertoire expressed in patients with rheumatoid arthritis. Eur J Immunol 1992; 22: 2901–6
   PubMed Web of Science ®Google Scholar
• Bröker B M, Korthäuer U, Heppt P, Weseloh G, de la Camp R, Kroczeck R A, et al. Biased T cell receptor usage in rheumatoid arthritis. Arthritis Rheum 1993; 36: 1234–43
   PubMedGoogle Scholar
• Miyawaki T, Uehara T, Nibu R, Tsuji T, Yachie A, Yone-Hara S, et al. Differential expression of apoptosis-related fas antigen on lymphocycte subpopulations in human peripheral blood. J Immunol 1992; 149: 3753–8
   PubMed Web of Science ®Google Scholar
• Hintzen R Q, de Jong R, Lens S MA, Brouwer M, Baars P, van Lier R AW. Regulation of CD27 expression on subsets of mature T-lymphocytes. J Immunol 1993; 151: 2426–35
   PubMed Web of Science ®Google Scholar