274
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Semi-solid dosage form of clonazepam for rapid oral mucosal absorption

, &
Pages 809-814 | Received 06 Sep 2010, Accepted 30 Nov 2010, Published online: 20 Jan 2011

References

  • Riss J, Cloyd J, Gates J, Collins S. (2008). Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand, 118:69–86.
  • Knudsen FU. (1979). Rectal administration of diazepam in solution in the acute treatment of convulsions in infants and children. Arch Dis Child, 54:855–857.
  • Scott RC, Besag FM, Neville BG. (1999). Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: a randomised trial. Lancet, 353:623–626.
  • Li L, Gorukanti S, Choi YM, Kim KH. (2000). Rapid-onset intranasal delivery of anticonvulsants: pharmacokinetic and pharmacodynamic evaluation in rabbits. Int J Pharm, 199:65–76.
  • Onishi H, Sakata O, Masuda K, Machida Y. (2005). Novel mucoadhesive oral patch containing diazepam. Drug Dev Ind Pharm, 31:607–613.
  • Rey E, Tréluyer JM, Pons G. (1999). Pharmacokinetic optimization of benzodiazepine therapy for acute seizures. Focus on delivery routes. Clin Pharmacokinet, 36:409–424.
  • Dahlin MG, Amark PE, Nergårdh AR. (2003). Reduction of seizures with low-dose clonazepam in children with epilepsy. Pediatr Neurol, 28:48–52.
  • Klosterskov Jensen P, Abild K, Nøhr Poulsen M. (1983). Serum concentration of clonazepam after rectal administration. Acta Neurol Scand, 68:417–420.
  • Rylance GW, Poulton J, Cherry RC, Cullen RE. (1986). Plasma concentrations of clonazepam after single rectal administration. Arch Dis Child, 61:186–188.
  • Schols-Hendriks MW, Lohman JJ, Janknegt R, Korten JJ, Merkus FW, Hooymans PM. (1995). Absorption of clonazepam after intranasal and buccal administration. Br J Clin Pharmacol, 39:449–451.
  • Sakata O, Onishi H, Machida Y. (2008). Clonazepam oral droplets for the treatment of acute epileptic seizures. Drug Dev Ind Pharm, 34:1376–1380.
  • Tsutsumi K, Obata Y, Takayama K, Loftsson T, Nagai T. (1998). Effect of cod-liver oil extract on the buccal permeation of ergotamine tartrate. Drug Dev Ind Pharm, 24:757–762.
  • Birudaraj R, Berner B, Shen S, Li X. (2005). Buccal permeation of buspirone: mechanistic studies on transport pathways. J Pharm Sci, 94:70–78.
  • Kondoh M. (2006). Claudin as a novel target for drug delivery system. Yakugaku Zasshi, 126:711–721.
  • Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 10th edn. New York: McGraw-Hill, 1944.
  • Ogiso T, Ito Y, Iwaki M, Yamamoto Y. (1989). Membrane-controlled transdermal therapeutic system containing clonazepam and anticonvulsant activity after its application. Chem Pharm Bull, 37:446–449.
  • Yamaoka K, Tanigawara Y, Nakagawa T, Uno T. (1981). A pharmacokinetic analysis program (multi) for microcomputer. J Pharmacobio-Dyn, 4:879–885.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.