Effect of vehicle systems, pH and enhancers on the permeation of highly lipophilic aripiprazole from Carbopol 971P gel systems across human cadaver skin

References

• Aggarwal G, Dhawan S. (2010). Psychotropic Drugs and transdermal Delivery: An Overview. International J of Pharma and Bio Science, 1 (2),
   Google Scholar
• Chein YW. Novel Drug Delivery systems. New York: Marcel Dekker, Inc; 1992: 1–42.
   Google Scholar
• Wiechers JW. (1989). The barrier function of the skin in relation to percutaneous absorption of drugs. Pharm Weekbl Sci, 11:185–198.
   PubMedGoogle Scholar
• Arellano A, Santoyo S, Martín C, Ygartua P. (1999). Influence of propylene glycol and isopropyl myristate on the in vitro percutaneous penetration of diclofenac sodium from carbopol gels. Eur J Pharm Sci, 7:129–135.
   PubMed Web of Science ®Google Scholar
• Subedi RK, Oh SY, Chun MK, Choi HK. (2010). Recent advances in transdermal drug delivery. Arch Pharm Res, 33:339–351.
   PubMed Web of Science ®Google Scholar
• Marjukka Suhonen T, Bouwstra JA, Urtti A. (1999). Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations. J Control Release, 59:149–161.
   PubMed Web of Science ®Google Scholar
• Kim JJ, Chi SC, Shim CK, Kim CK. (1992). Effect of Tween 20 on the penetration of ketoprofen through excised rat skin. J Kor Pharm Sci, 22:163–166.
   Google Scholar
• Kim CK, Kim JJ, Chi SC, Shim CK. (1993). Effect of fatty acids and urea on the penetration of ketoprofen through rat skin. Int J Pharm, 99:109–118.
   Web of Science ®Google Scholar
• Lee CK, Uchida T, Noguchi E, Kim NS, Goto S. (1993). Skin permeation enhancement of tegafur by ethanol/panasate 800 or ethanol/water binary vehicle and combined effect of fatty acids and fatty alcohols. J Pharm Sci, 82:1155–1159.
   PubMed Web of Science ®Google Scholar
• Carelli V, Di Colo G, Nannipieri E, Serafini MF. (1998). Effect of vehicles on yohimbine permeation across excised hairless mouse skin. Pharm Acta Helv, 73:127–134.
   PubMedGoogle Scholar
• Otto A, Wiechers JW, Kelly CL, Hadgraft J, du Plessis J. (2008). Effect of penetration modifiers on the dermal and transdermal delivery of drugs and cosmetic active ingredients. Skin Pharmacol Physiol, 21:326–334.
   PubMed Web of Science ®Google Scholar
• Adrian PF, Roman S, Hans WM, Clemens G, Rainer HM, Ralph L. Transdermal delivery of highly lipophilic drugs: In vitro fluxes of antiestrogens, permeation enhancers, and solvents from liquid formulations. Pharmaceutical Research, Vol. 19, No. 5, May 2002.
   Web of Science ®Google Scholar
• Chisty MNA, Plakogiannis MF, Bellantone RA, Taft DR. “In vitro evaluation of the release of albuterol sulfate from polymer gels: Effect of fatty acids on drug transport across biological membranes”. Drug Development and Industrial Pharmacy, Vol 28, No. 10, pp. 1221–1229, 2002.
   PubMed Web of Science ®Google Scholar
• Narisetty ST, Ramesh P. (2003). Transdermal delivery of zidovudine: Effect of vehicles on permeation across rat skin and their mechanism of action. European J of Pharmaceutical Sciences, 18:71–79.
   PubMed Web of Science ®Google Scholar
• Ostrenga J, Haleblian J, Poulsen B, Ferrell B, Mueller N, Shastri S. (1971). Vehicle design for a new topical steroid, fluocinonide. J Invest Dermatol, 56:392–399.
   PubMed Web of Science ®Google Scholar
• Møllgaard B, Hoelgaard A. (1983). Vehicle effect on topical drug delivery. II. Concurrent skin transport of drugs and vehicle components. Acta Pharm Suec, 20:443–450.
   PubMedGoogle Scholar
• Han-Joon O, Yu-Kyoung O, Chong-Kook K. (2001). Effects of vehicles and enhancers on transdermal delivery of melatonin. Int J Pharm, 212:63–71.
   PubMed Web of Science ®Google Scholar
• Seyed AM, Reza A. (2003). An investigation into the effect of various penetration enhancers on percutaneous absorption of piroxicam. Iranian J Pharm Research, 2:135–140.
   Google Scholar
• Sato A, Friend O, Nagai I. (1988). Effect and mode of action of aliphatic esters. Int J Pharm, 43:31–40.
   Web of Science ®Google Scholar
• Sasaki H, Kojima M, Nakamura J, Shibasaki J. (1990). Enhancing effect of combining two pyrrolidone vehicles on transdermal drug delivery. J Pharm Pharmacol, 42:196–199.
   PubMed Web of Science ®Google Scholar
• Phillips CA, Michniak BB. (1995). Transdermal delivery of drugs with differing lipophilicities using azone analogs as dermal penetration enhancers. J Pharm Sci, 84:1427–1433.
   PubMed Web of Science ®Google Scholar
• Sinha VR, Kaur MP. (2000). Permeation enhancers for transdermal drug delivery. Drug Dev Ind Pharm, 26:1131–1140.
   PubMed Web of Science ®Google Scholar
• Asbill CS, El-Kattan AF, Michniak B. (2000). Enhancement of transdermal drug delivery: Chemical and physical approaches. Crit Rev Ther Drug Carrier Syst, 17:621–658.
   PubMed Web of Science ®Google Scholar
• Kenneth AW, Keith RB, Darren MG, Valerie JJ, Adam CW, Robert HS. (1998). Comparison of the transdermal delivery of estradiol from two gel formulations. Maturitas, 29:189–195.
   PubMed Web of Science ®Google Scholar
• Williams AC. Transdermal and topical drug delivery. Lotion: Pharmaceutical Press; 2003.
   Google Scholar
• Koizumi A, Fujii M, Kondoh M, Watanabe Y. (2004). Effect of N-methyl-2-pyrrolidone on skin permeation of estradiol. Eur J Pharm Biopharm, 57:473–478.
   PubMed Web of Science ®Google Scholar
• Williams AC, Barry BW. (2004). Penetration enhancers. Adv Drug Deliv Rev, 56:603–618.
   PubMed Web of Science ®Google Scholar
• Chantasart D, Sa-Nguandeekul P, Prakongpan S, Li SK, Higuchi WI. (2007). Comparison of the effects of chemical permeation enhancers on the lipoidal pathways of human epidermal membrane and hairless mouse skin and the mechanism of enhancer action. J Pharm Sci, 96:2310–2326.
   PubMed Web of Science ®Google Scholar
• Ogiso T, Paku T, Iwaki M, Tanino T. (1995). Percutaneous penetration of fluorescein isothiocyanate-dextrans and the mechanism for enhancement effect of enhancers on the intercellular penetration. Biol Pharm Bull, 18:1566–1571.
   PubMed Web of Science ®Google Scholar
• Goates CY, Knutson K. (1993). Enhanced permeation and stratum corneum structural alterations in the presence of dithiothreitol. Biochim Biophys Acta, 1153:289–298.
   PubMed Web of Science ®Google Scholar
• Ibrahim SA, Li SK. (2010). Efficiency of fatty acids as chemical penetration enhancers: Mechanisms and structure enhancement relationship. Pharm Res, 27:115–125.
   PubMed Web of Science ®Google Scholar
• Kandimalla K, Kanikkannan N, Andega S, Singh M. (1999). Effect of fatty acids on the permeation of melatonin across rat and pig skin in vitro and on the transepidermal water loss in rats in vivo. J Pharm Pharmacol, 51:783–790.
   PubMed Web of Science ®Google Scholar
• Aungst BJ. (1989). Structure/effect studies of fatty acid isomers as skin penetration enhancers and skin irritants. Pharm Res, 6:244–247.
   PubMed Web of Science ®Google Scholar
• Aungst BJ, Rogers NJ, Shefter E. (1986). Enhancement of naloxone penetration through human skin in vitro using fatty-acids, fatty alcohols, surfactants. sulfoxides and amides. Int J Pharm, 33:225–234.
   Web of Science ®Google Scholar
• Ongpipattanakul B, Burnette RR, Potts RO, Francoeur ML. (1991). Evidence that oleic acid exists in a separate phase within stratum corneum lipids. Pharm Res, 8:350–354.
   PubMed Web of Science ®Google Scholar
• Ogiso T, Shintani M. (1990). Mechanism for the enhancement effect of fatty acids on the percutaneous absorption of propranolol. J Pharm Sci, 79:1065–1071.
   PubMed Web of Science ®Google Scholar
• Elyan BM, Sidhom MB, Plakogiannis FM. (1996). Evaluation of the effect of different fatty acids on the percutaneous absorption of metaproterenol sulfate. J Pharm Sci, 85:101–105.
   PubMed Web of Science ®Google Scholar
• Pose-Vilarnovo B, Rodríguez-Tenreiro C, Rosa dos Santos JF, Vázquez-Doval J, Concheiro A, Alvarez-Lorenzo C et al. (2004). Modulating drug release with cyclodextrins in hydroxypropyl methylcellulose gels and tablets. J Control Release, 94:351–363.
   PubMed Web of Science ®Google Scholar
• Wang YY, Hong CT, Chiu WT, Fang JY. (2001). In vitro and in vivo evaluations of topically applied capsaicin and nonivamide from hydrogels. Int J Pharm, 224:89–104.
   PubMed Web of Science ®Google Scholar
• Das MK, Ahmed AB. (2007). Formulation and ex vivo evaluation of rofecoxib gel for topical application. Acta Pol Pharm, 64:461–467.
   PubMedGoogle Scholar
• Zhou M, Donovan MD. (1996). Intranasal mucocilliary clearance of putative bioadhesive polymer gels. Int J Pharm, 135:115–125.
   Web of Science ®Google Scholar
• Shin SC, Kim HJ, Oh IJ, Cho CW, Yang KH. (2005). Development of tretinoin gels for enhanced transdermal delivery. Eur J Pharm Biopharm, 60:67–71.
   PubMed Web of Science ®Google Scholar
• Shin SC, Kim JY, Oh IJ. (2000). Mucoadhesive and physicochemical characterization of Carbopol-Poloxamer gels containing triamcinolone acetonide. Drug Dev Ind Pharm, 26:307–312.
   PubMed Web of Science ®Google Scholar