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ORIGINAL ARTICLEClinical Translational Therapeutics

Adeno-Associated Virus Harboring Fusion Gene NT4-Ant-Shepherdin Induce Cell Death in Human Lung Cancer Cells

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Pages 465-471 | Published online: 07 Dec 2009

REFERENCES

  • Ambrosini, G.; Adida, C.; Altieri, D.C. A novel anti-apoptosis gene survivin expressed in cancer and lymphama. J Nat Med 1997, 3(8), 917–921.
  • Altieri, D.C. Survivin, versatile modulation of cell division and apoptosis in cancer. Oncogene 2003, 22(53), 8581–8589.
  • Falleni, M.; Pellegrini, C.; Marchetti, A.; Oprandi, B.; Buttitta, F.; Barassi, F.; Santambrogio, L.; Coggi, G.; Bosari, S. Survivin gene expression in early-stage non-small cell lung cancer. J Pathol 2003, 200(5), 620–626.
  • Singhal, S.; Vachani, A.; Antin-Ozerkis, D.; Kaiser, L.R.; Albelda, S.M. Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a review. Clin Cancer Res 2005, 11(11), 3974–3986.
  • Jiang, X.; Wilford, C.; Duensing, S.; Munger, K.; Jones, G.; Jones, D. Participation of survivin in mitotic and apoptotic activities of normal and tumor-derived cells. J Cell Biochem 2001, 83(2), 342–354.
  • Skonfias, D.A.; Mollinari, C.; Lacroix, F.B.; Margolis, R.L. Human survivin is a kinetochore-associated passenger protein. J Cell Biol 2000, 151(7), 1575–1582.
  • Blanc-Brude, O.P.; Mesri, M.; Wall, N.R.; Plescia, J.; Dohi, T.; Altieri, D.C. Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis. Clin Cancer Res 2003, 9(6), 2683–2692.
  • Zangemeister-Wittke, U. Antisense to apoptosis inhibitors facilitates chemotherapy and TRAIL-induced death signaling. Ann NY Acad Sci 2003, 1002, 90–94.
  • Wall, N.R.; O'Connor, D.S.; Plescia, J.; Pommier, Y.; Altieri, D.C. Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis. Cancer Res 2003, 63, 230–235.
  • Pennati, M.; Binda, M.; Colella, G.; Zoppe', M.; Folini, M.; Vignati, S.; Valentini, A.; Citti, L.; De Cesare, M.; Pratesi, G.; Giacca, M.; Daidone, M.G.; Zaffaroni, N. Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells. Oncogene 2004, 23, 386–394.
  • Uchida, H.; Tanaka, T.; Sasaki, K.; Kato, K.; Dehari, H.; Tto, Y.; Kobune, M.; Miyagishi, M.; Taira, K.; Tahara, H.; Hamada, H. Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo. Mol Ther 2004, 10, 162–171.
  • Siegel, S.; Wagner, A.; Schmitz, N.; Zeis, M. Induction of antiumour immunity using survivin peptide pulsed dendritic cells in a murine lymphoma model. Br J Haematol 2003, 122, 911–914.
  • Xiang, R.; Mizutani, N.; Luo, Y.; Chiodoni, C.; Zhou, H.; Mizutani, M.; Ba, Y.; Becker, J.C.; Reisfeld, R.A. A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication. Cancer Res 2005, 65, 553–561.
  • Chang, C.C.; Heller, J.D.; Kuo, J.; Huang, R.C. Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression. Proc Natl Acad Sci USA 2004, 101, 13239–13244.
  • Fortugno, P.; Beltrami, E.; Plecia, J.; Fontana, J.; Pradhan, D.; Marchisio, P.C.; Sessa, W.C.; Altieri, D.C. Regulation of survivin function by Hsp90. PNAS 2003, 100(11), 13791–13796.
  • Plecia, J.; Salz, W.; Xia, F.; Pennati, M.; Zaffaroni, N.; Daidone, M.G.; Meli, M.; Dohi, T.; Fortugno, P.; Nefedova, Y.; Gabrilovich, D.I.; Colombo, G.; Altieri, D.C. Rational design of shepherdin,a novel anticancer agent. Cancer Cell 2005, 7(5), 457–468.
  • Bradford, M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72, 248–254.
  • Laemmli, U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227, 680–685.
  • Jiang, X.; Wilford, C.; Duensing, S.; Participation of Survivin in mitotic and apoptotic activities of normal and tumor-derived cells. J Cell Biochem 2001, 83(2), 342–354.
  • Smith, D.J.; Leil, T.A.; Liu, X. Neurotrophin-4 is required for tolerance to morphine in the mouse. Neurosci Lett 2003, 340(2), 103–106.
  • Timmusk, T.; Belluardo, N.; Metsis, M.; Persson, H. Widespread and developmentally regulated expression of neurotrophin-4 mRNA in rat brain and peripheral tissues. Eur J Neurosci 1993, 5(6), 605–613.
  • Ip, N.Y.; Ibanez, C.F.; Nye, S.H.; McClain, J.; Jones, P.P.; Gies, D.R.; Belluscio, L.; Le Beau, MM; Espinosa, R.3rd; Squinto, S.P. Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution receptor specificity. Proc Natl Acad Sci USA 1997, 89(7), 3060–3064.
  • Yu, Y.; Jiang, W.; Xin, Y.; Senglin, H. The construction of NT4 (Si)- NAP fusion gene vector and its expression in Ecoli. J Neurol 2004, 37(3), 260–261. In Chinese.
  • Li, Y.; Qiu, S.; Song, L.; Yan, Q.; Yang, G. Secretory expression of p53(N15)-ant following lentivirus-mediated gene transfer induces cell death in human cancer cells. Cancer Invest 2008, 26, 28–34.
  • Flotte, T.R. Gene therapy progress and prospects: recombinant adeno-associated virus (rAAV) vectors. Gene Ther 2004, 11, 805–810.

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