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REVIEW ARTICLE

What do we actually know about the relationship between arterial hypertension and atrial fibrillation?

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Pages 81-88 | Received 26 Jan 2013, Accepted 28 May 2013, Published online: 29 Jul 2013

References

  • Go AS, Hylek EM, Phillips KA, Chang Y, Henault LE, Selby JV, et al. Prevalence of diagnosed atrial fibrillation in adults. JAMA. 2001;285:2370–2375.
  • Chugh SS, Blackshear JL, Shen W-K, Hammill SC, Gersh BJ. Epidemiology and natural history of atrial fibrillation: Clinical implications. J Am Coll Cardiol. 2001;37:371–378.
  • Zateyshchikov DA, Brovkin AN, Chistiakov DA, Nosikov VV. Advanced age, low left atrial appendage velocity, and factor V promoter sequence variation as predictors of left atrial thrombosis in patients with nonvalvular atrial fibrillation. J Thromb Thrombolysis. 2010;30:192–199.
  • Russell D. Atrial fibrillation and stroke. Cerebrovasc Dis. 2012;33:23.
  • Wolf P, Abbott R, Kannel W. Atrial fibrillation as an independent risk factor for stroke: The Framingham study. Stroke. 1991;22:983–988.
  • Kearney PM, Whelton M, Reynolds K, Whelton PK, He J. Worldwide prevalence of hypertension: A systematic review. J Hypertens. 2004;22:11–19.
  • Nieuwlaat R, Capucci A, Camm AJ, Olsson SB, Andresen D, Davies DW, et al. Atrial fibrillation management: A prospective survey in ESC member countries: The Euro Heart Survey on Atrial Fibrillation. Eur Heart J. 2005;26:2422–2434.
  • Kannel WB, Wolf PA, Benjamin EJ, Levy D. Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: Population-based estimates. Am J Cardiol. 1998; 82 Suppl:2N–9N.
  • Grundvold I, Skretteberg PT, Liestøl K, Erikssen G, Kjeldsen SE, Arnesen H, et al. Upper normal blood pressures predict incident atrial fibrillation in healthy middle-aged men: A 35-year follow-up study. Hypertension. 2012;59:198–204.
  • Rosiak M, Dziuba M, Chudzik M, Cygankiewicz I, Bartczak K, Drozdz J, et al. Risk factors for atrial fibrillation: Not always severe heart disease, not always so “lonely”. Cardiol J. 2010;17:437–442.
  • Wyse DG, Waldo AL, DiMarco JP, Domanski MJ, Rosenberg Y, Schron EB, et al. Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators. A comparison of rate control and rhythm control in patients with atrial fibrillation. N Engl J Med. 2002;347:1825–1833.
  • Patel MR, Mahaffey KW, Garg J, Pan G, Singer DE, Hacke W, et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011;365:883–891.
  • Benjamin EJ, Levy D, Vaziri SM, D’Agostino RB, Belanger AJ, Wolf PA. Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study.JAMA. 1994; 271:840–844.
  • Nagarakanti R, Ezekowitz M. Diastolic dysfunction and atrial fibrillation. J Interv Card Electrophysiol. 2008;22:111–118.
  • Kalogeropoulos AS, Tsiodras S, Rigopoulos AG, Sakadakis EA, Triantafyllis A, Kremastinos DT, et al. Novel association patterns of cardiac remodeling markers in patients with essential hypertension and atrial fibrillation. BMC Cardiovasc Disord. 2011;11:77–83.
  • Go O, Rosendorff C. Hypertension and atrial fibrillation. Curr Cardiol Rep. 2009;11:430–435.
  • Manolis AJ, Rosei EA, Coca A, Cifkova R, Erdine SE, Kjeldsen S, et al. Hypertension and atrial fibrillation: Diagnostic approach, prevention and treatment. Position paper of the Working Group “Hypertension Arrhythmias and Thrombosis” of the European Society of Hypertension. J Hypertens. 2012;30:239–252.
  • Nattel S, Dobrev D. The multidimensional role of calcium in atrial fibrillation pathophysiology: Mechanistic insights and therapeutic opportunities. Eur Heart J. 2012;33:1870–1877.
  • Van Gelder IC, Hemels ME. The progressive nature of atrial fibrillation: A rationale for early restoration and maintenance of sinus rhythm. Europace. 2006;8:943–949.
  • Byrd GD, Prasad SM, Ripplinger CM, Cassilly TR, Schuessler RB, Boineau JP, et al. Importance of geometry and refractory period in sustaining atrial fibrillation. Testing the Critical Mass Hypothesis. Circulation. 2005;112 Suppl 1:I7–I13.
  • Parati G, Esler M. The human sympathetic nervous system: Its relevance in hypertension and heart failure. Eur Heart J. 2012;33:1058–1066.
  • Lu Z, Scherlag BJ, Lin J, Niu G, Fung KM, Zhao L, et al. Atrial fibrillation begets atrial fibrillation: Autonomic mechanism for atrial electrical remodeling induced by short-term rapid atrial pacing. Circ Arrhythm Electrophysiol. 2008;1:184–192.
  • Dimmer C, Tavernier R, Gjorgov N, Van Nooten G, Clement DL, Jordaens L. Variations of autonomic tone preceding onset of atrial fibrillation after coronary artery bypass grafting. Am J Cardiol. 1998;82:22–25.
  • Coccagna G, Capucci A, Bauleo S, Boriani G, Santarelli A. Paroxysmal atrial fibrillation in sleep. Sleep. 1997;20: 396–398.
  • Herweg B, Dalal P, Nagy B, Schweitzer P. Power spectral analysis of heart period variability of preceding sinus rhythm before initiation of paroxysmal atrial fibrillation. Am J Cardiol 1998; 82:869–874.
  • Patterson E, Po SS, Scherlag BJ, Lazzara R. Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation. Heart Rhythm. 2005;2:624–631.
  • Choi EK, Shen MJ, Han S, Hwang S, Sayfo S, Piccirillo G, et al. Intrinsic cardiac nerve activity and paroxysmal atrial tachyarrhythmia in ambulatory dogs. Circulation. 2010; 121: 2615–2623.
  • Goette A, Staack T, Rocken C, Arndt M, Geller JC, Huth C, et al. Increased expression of extracellular signal-regulated kinase and angiotensin converting enzyme in human atria during atrial fibrillation. J Am Coll Cardiol. 2000;35: 1669–1677.
  • McEwan PE, Gray GA, Sherry L, Webb DJ, Kenyon CJ. Differential effects of angiotensin II on cardiac cell proliferation and intramyocardial perivascular fibrosis in vivo. Circulation. 1998; 98:2765–2773.
  • Stockand JD, Meszaros JG. Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-Ras and MAPK1/2 signaling. Am J Physiol Heart Circ Physiol. 2003; 284:176–184.
  • Mukherjee R, Herron AR, Lowry AS, Stroud RE, Stroud MR, Wharton JM, et al. Selective induction of matrix metalloproteinases and tissue inhibitor of metalloproteinases in atrial and ventricular myocardium in patients with atrial fibrillation. Am J Cardiol. 2006;15:532–537.
  • Ehrlich JR, Hohnloser SH, Nattel S. Role of angiotensin system and effects of its inhibition in atrial fibrillation: Clinical and experimental evidence. Eur Heart J. 2006;27:512–518.
  • Grassi G. Renin–angiotensin–sympathetic crosstalks in hypertension: Reappraising the relevance of peripheral interactions. J Hypertens. 2001;19:1713–1716.
  • Mitchell GF, Vasan RS, Keyes MJ, Parise H, Wang TJ, Larson MG, et al. Pulse pressure and risk of new-onset atrial fibrillation. JAMA. 2007;297:709–715.
  • Larstorp AC, Ariansen I, Gjesdal K, Olsen MH, Ibsen H, Devereux RB, et al. Association of pulse pressure with new-onset atrial fibrillation in patients with hypertension and left ventricular hypertrophy: The Losartan Intervention For Endpoint (LIFE) reduction in hypertension study. Hypertension. 2012;60:347–353.
  • Verdecchia P, Dagenais G, Healey J, Gao P, Dans AL, Chazova I, et al. Blood pressure and other determinants of new-onset atrial fibrillation in patients at high cardiovascular risk in the Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease studies. ONTARGET-TRANSCEND study. J Hypertens. 2012;30:1004–1014.
  • Conen D, Tedrow UB, Koplan BA, Glynn RJ, Buring JE, Albert CM. Influence of systolic and diastolic blood pressure on the risk of incident atrial fibrillation in women. Circulation. 2009;119:2146–2152.
  • Hurley V, Ireson R, Fletcher K, Lip GY, Hobbs FD, Mant J; BAFTA Investigators. A cross-sectional study of hypertension in an elderly population (75 years and over) with atrial fibrillation: Secondary analysis of data from the Birmingham Atrial Fibrillation in the Aged (BAFTA) randomised controlled trial. Int J Cardiol. 2007;117:152–156.
  • Thacker EL, McKnight B, Psaty BM, Longstreth WT Jr, Dublin S, Jensen PN, et al. Association of body mass index, diabetes, hypertension, and blood pressure levels with risk of permanent atrial fibrillation. J Gen Intern Med. 2013;28: 247–253.
  • Pierdomenico SD, Lapenna D, Cuccurullo F. Risk of atrial fibrillation in dipper and nondipper sustained hypertensive patients. Blood Press Monit 2008;13:193–197.
  • Webb AJ, Rothwell PM. Blood pressure variability and risk of new-onset atrial fibrillation: A systematic review of randomized trials of antihypertensive drugs. Stroke. 2010; 41:2091–2093.
  • Pedersen OD, Bagger H, Kober L, Torp-Pedersen C. Trandolapril reduces the incidence of atrial fibrillation after acute myocardial infarction in patients with left ventricular dysfunction. Circulation. 1999;100:376–380.
  • Hansson L, Lindholm LH, Ekbom T, Dahlof B, Lanke J, Schersten B, et al. Randomised trial of old and new antihypertensive drugs in elderly patients: Cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study. Lancet. 1999;354:1751–1756.
  • Hansson L, Lindholm LH, Niskanen L, Lanke J, Hedner T, Niklason A, et al. Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: The Captopril Prevention Project (CAPPP) randomised trial. Lancet. 1999;353:611–616.
  • L’Allier PL, Ducharme A, Keller PF, Yu H, Guertin MC, Tardif JC. Angiotensin converting enzyme inhibition in hypertensive patients is associated with a reduction in the occurrence of atrial fibrillation. J Am Coll Cardiol. 2004; 44:159–164.
  • Wachtell K, Lehto M, Gerdts E, Olsen MH, Hornestam B, Dahlöf B, et al. Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: The Losartan Intervention For End Point Reduction in Hypertension (LIFE) study. J Am Coll Cardiol. 2005;45:712–719.
  • Schmieder RE, Kjeldsen SE, Julius S, McInnes GT, Zanchetti A, Hua TA. Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: The VALUE trial. J Hypertens. 2008;26:403–411.
  • Yusuf S, Diener HC, Sacco RL, Cotton D, Ounpuu S, Lawton WA, et al. Telmisartan to prevent recurrent stroke and cardiovascular events. N Engl J Med. 2008;359:1225–1237.
  • , ONTARGET InvestigatorsYusuf S, Teo KK, Pogue J, Dyal L, Copland I, Schumacher H, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med. 2008; 358:1547–1559.
  • , GISSI-AF InvestigatorsDisertori M, Latini R, Barlera S, Franzosi MG, Staszewsky L, et al. Valsartan for prevention of recurrent atria fibrillation. N Engl J Med. 2009;360: 1606–1617.
  • Fogari R, Derosa G, Ferrari I, Corradi L, Zoppi A, Lazzari P, et al. Effect of valsartan and ramipril on atrial fibrillation recurrence and P-wave dispersion in hypertensive patients with recurrent symptomatic lone atrial fibrillation. Am J Hypertens. 2008;21:1034–1039.
  • Fogari R, Mugellini A, Destro M, Corradi L, Zoppi A, Fogari E, et al. Losartan and prevention of atrial fibrillation recurrence in hypertensive patients. J Cardiovasc Pharmacol. 2006;47:46–50.
  • Galzerano D, Caselli, S, Breglio R. A multicentre, randomized study comparing efficacy of telmisartan versus carvedilol in preventing atrial fibrillation recurrence in hypertensive patients. Circulation. 2007;116 Suppl II:556–557.
  • Disertori M, Barlera S, Staszewsky L, Latini R, Quintarelli S, Franzosi MG. Systematic review and meta-analysis: Renin–angiotensin system inhibitors in the prevention of atrial fibrillation recurrences: An unfulfilled hope. Cardiovasc Drugs Ther. 2012;26:47–54.
  • Huang G, Xu JB, Liu JX, He Y, Nie XL, Li Q, et al. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers decrease the incidence of atrial fibrillation: A meta-analysis. Eur J Clin Invest. 2011;41:719–733.
  • Lally JA, Gnall EM, Seltzer J, Kowey PR. Non-antiarrhythmic drugs in atrial fibrillation: A review of non-antiarrhythmic agents in prevention of atrial fibrillation. J Cardiovasc Electrophysiol. 2007;18:1222–1228.
  • Wachtell K, Devereux RB, Lyle PA. Use of beta-blockers, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers to prevent atrial fibrillation. Curr Cardiol Rep. 2006;8:356–364.
  • Healey JS, Baranchuk A, Crystal E, Morillo CA, Garfinkle M, Yusuf S, Connolly SJ. Prevention of atrial fibrillation with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: A metaanalysis. J Am Coll Cardiol. 2005; 45:1832–1839.
  • Kalus JS, Coleman CI, White CM. The impact of suppressing the renin–angiotensin system on atrial fibrillation. J Clin Pharmacol. 2006;46:21–28.
  • Schneider MP, Hua TA, Bohm M, Wachtell K, Kjeldsen SE, Schmieder RE. Prevention of atrial fibrillation by renin–angiotensin system-inhibition a meta-analysis. J Am Coll Cardiol. 2010; 55:2299–2307.
  • Bhuriya R, Singh M, Sethi A, Molnar J, Bahekar A, Singh PP, et al. Prevention of recurrent atrial fibrillation with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers: A systematic review and meta-analysis of randomized trials. J Cardiovasc Pharmacol Ther. 2011;16: 178–184.
  • Zhang Y, Zhang P, Mu Y, Gao M, Wang JR, Wang Y, et al. The role of renin–angiotensin system blockade therapy in the prevention of atrial fibrillation: A meta-analysis of randomized controlled trials. Clin Pharmacol Ther. 2010; 88:521–531.
  • Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, et al. 2007 Guidelines for the Management of Arterial Hypertension: The task force for the management of arterial hypertension of the European Society of Hypertension (esh) and of the European Society of Cardiology (ESC). J Hypertens. 2007;25:1105–1187.
  • Wachtell K, Gerdts E, Aurigemma GP, Boman K, Dahlöf B, Nieminen MS, et al. In-treatment reduced left atrial diameter during antihypertensive treatment is associated with reduced new-onset atrial fibrillation in hypertensive patients with left ventricular hypertrophy: The LIFE Study. Blood Press. 2010;19:169–175.
  • Okin PM, Devereux RB, Jern S, Kjeldsen SE, Julius S, Nieminen MS, et al. Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events. JAMA. 2004;292:2343–2349.
  • Werner C, Pöss J, Böhm M. Optimal antagonism of the renin–angiotensin–aldosterone system: Do we need dual or triple therapy?Drugs. 2010;70:1215–1230.
  • Zannad F, McMurray JJ, Krum H, van Veldhuisen DJ, Swedberg K, Shi H, et al. Eplerenone in patients with systolic heart failure and mild symptoms. N Engl J Med. 2011;364: 11–21.
  • Solomon SD, Appelbaum E, Manning WJ, Verma A, Berglund T, Lukashevich V, et al. Aliskiren in Left Ventricular Hypertrophy (ALLAY) Trial Investigators. Effect of the direct renin inhibitor aliskiren, the angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy. Circulation. 2009;11:530–537.
  • Nasr IA, Bouzamondo A, Hulot JS, Dubourg O, Le Heuzey JY, Lechat P. Prevention of atrial fibrillation onset by beta-blocker treatment in heart failure: A meta-analysis. Eur Heart J. 2007;28:457–462.
  • Schaer BA, Schneider C, Jick SS, Conen D, Osswald S, Meier CR. Risk for incident atrial fibrillation in patients who receive antihypertensive drugs: A nested case-control study. Ann Intern Med. 2010;152:78–84.
  • De Simone A, Stabile G, Vitale DF, Turco P, Di Stasio M, Petrazzuoli F, et al. Pretreatment with verapamil in patients with persistent or chronic atrial fibrillation who underwent electrical cardioversion. J Am Coll Cardiol. 1999;34: 810–814.
  • Lee SH, Yu WC, Cheng JJ, Hung CR, Ding YA, Chang MS, Chen SA. Effect of verapamil on long-term tachycardia-induced atrial electrical remodeling. Circulation 2000; 101:200–206.
  • Bandeali SJ, Kayani WT, Lee VV, Elayda M, Alam M, Huang HD, et al. Association between preoperative diuretic use and in-hospital outcomes after cardiac surgery. Cardiovasc Ther. 2013 Mar 20. doi: 10.1111/1755–5922.12024. [Epub ahead of print].
  • Chelazzi C, Villa G, De Gaudio AR. Postoperative atrial fibrillation. ISRN Cardiol. 2011;2011:203179.
  • Edwards JD, Wilkins RG. Atrial fibrillation precipitated by acute hypovolaemia. Br Med J (Clin Res Ed). 1987;294: 283–284.
  • Gottdiener JS, Reda DJ, Williams DW, Materson BJ, Cushman W, Anderson RJ. Effect of single-drug therapy on reduction of left atrial size in mild to moderate hypertension: Comparison of six antihypertensive agents. Circulation. 1998;98: 140–148.
  • Gottdiener JS, Reda DJ, Massie BM, Materson BJ, Williams DW, Anderson RJ. Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: Comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. Circulation. 1997;95: 2007–2014.
  • Conti A, Canuti E, Mariannini Y, Zanobetti M, Innocenti F, Paladini B, et al. Aggressive approach and outcome in patients presenting atrial fibrillation and hypertension. Int J Cardiol. 2011 Oct 8. [Epub ahead of print].

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