Publication Cover
Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 41, 2012 - Issue 3
258
Views
13
CrossRef citations to date
0
Altmetric
Research Article

Vaccination of Mice with ORF5 Plasmid DNA of PRRSV; Enhanced Effects by Co-immunizing with Porcine IL-15

, , , , &
Pages 231-248 | Published online: 21 Oct 2011

REFERENCES

  • Barfoed, A. M., Blixenkrone-Møller, M., Jensen, M. H., Bøtner, A., Kamstrup, S. (2004). DNA vaccination of pigs with open reading frame 1-7 of PRRS virus. Vaccine 22:3628–3641.
  • Carson, W. E., Giri, J. G., Lindemann, M. J., Linett, M. L., Ahdieh, M., Paxton, R., Anderson, D., Eisenmann, J., Grabstein, K., Caligiuri, M. A. (1994). Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J. Exp. Med. 180: 1395–1403.
  • Carson, W. E., Ross, M. E., Baiocchi, R. A., Marien, M. J., Boiani, N., Grabstein, K., Caligiuri, M. A. (1995). Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro. J. Clin. Invest. 96: 2578–2582.
  • Costers, S., Lefebvre, D. J., Goddeeris, B., Delputte, P. L., Nauwynck, H. J. (2009). Functional impairment of PRRSV-specific peripheral CD3+CD8high cells. Vet. Res. 40:46.
  • Dea, S., Bilodeau, R., Athanasious, R., Sauvageau, R., Martineau, G. P. (1992). Swine reproductive and respiratory syndrome in Quebec: isolation of an enveloped virus serologically-related to Lelystad virus. Can. Vet. J. 33:801–808.
  • Doherty, T. M., Seder, R. A., Sher, A. (1996). Induction and regulation of IL-15 expression in murine macrophages. J. Immunol. 156:735–741.
  • Faaberg, K. S., Hocker, J. D., Erdman, M. M., Harris, D. L., Nelson, E. A., Torremorell, M., Plagemann, P. G. (2006). Neutralizing antibody responses of pigs infected with natural GP5 N-glycan mutants of porcine reproductive and respiratory syndrome virus. Viral. Immunol. 19: 294–304.
  • Grabstein, K. H., Eisenman, J., Shanebeck, K., Rauch, C., Srinivasan, S., Fung, V., Beers, C., Richardson, J., Schoenborn, M. A., Ahdieh, M., Johnson, L., Alderson, M. A., Watson, J. D., Anderson, D. M., Giri, J. G. (1994). Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 264:965–968.
  • Henke, A., Chiang, C. S., Zell, R., Stelzner, A., 2004. Co-expression of interleukin-2 to increase the efficacy of DNA vaccine-mediated protection in coxsackievirus B3-infected mice. Antiviral Res. 64:131–136.
  • Jiang, W., Jiang, P., Wang, X., Li, Y., Du, Y., Wang, X. (2008). Enhanced immuneresponses of mice inoculatedrecombinant adenoviruses expressing GP5 by fusion with GP3 and/or GP4 of PRRS virus. Virus Res. 136:50–57.
  • Kanai, T., Thomas, E. K., Yasutomi, Y., Letvin, N. L. (1996). IL-15 stimulates the expansion of AIDS virus-specific CTL. J. Immunol. 157: 3681–3687.
  • Kang, J., Zuckermann, F., Ross, G., Yang, S., Osorio, F., Liu, W., Low, S. (1999). Antibody and cellular immune responses of swine following immunization with plasmid DNA encoding the PRRS virus ORFs 4, 5, 6 and 7. Res. Vet. Sci. 67:197–199.
  • Keffaber, K. K. (1989). Reproductive failure of unknown etiology. Am. Assoc. Swine Pract. News 1: 1–9.
  • Kutzler, M. A., Robinson, T. M., Chattergoon, M. A., Choo, D.K ., Choo, A. Y., Choe, P. Y., Ramanathan, M. P., Parkinson, R., Kudchodkar, S., Tamura, Y., Sidhu, M., Roopchand, V., Kim, J. J., Pavlakis, G. N., Felber, B. K., Waldmann, T. A., Boyer, J. D., Weiner, D. B. (2005). Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. J. Immunol. 175:112–123.
  • Liu, B., Li, G., Sui, X., Yin, J., Wang, H., Ren, X. (2009). Expression and functional analysis of porcine aminopeptidase N produced in prokaryotic expression system. J. Biotechnol. 141:91–96.
  • Lopez, O. J., Osorio, F. A. (2004). Role of neutralizing antibodies in PRRSV protective immunity. Vet. Immunol. Immunopathol. 102:155–163.
  • Ma, M., Jin, N., Liu, H.J., Zheng, M., Shen, G., Zhu, G., Lu, H., Huo, X., Jin, M., Li, X., Ma, H., Ji, Y., Yin, G., Jin, K. (2007). Immunogenicity of plasmids encoding P12A and 3C of FMDV and swine IL-18. Antiviral Res. 76:59–67.
  • Meier, W. A., Galeota, J., Osorio, F. A. (2003). Gradual development of the interferon-gamma response of swine to porcine reproductive and respiratory syndrome virus infection or vaccination. Virol. 309:18–31.
  • Meier, W., Wheeler, J., Husmann, R. J., Osoriob, F., Zuckermanna, F. A. (2000). Characteristics of the immune response of pigs to PRRS virus. Vet. Res. 31:41.
  • Mengeling, W. L., Lager, K. M., Vorwald, A. C. (1999). Safety and efficacy of vaccination of pregnant gilts against porcine reproductive and respiratory syndrome. Vet. Res. 60:796–801.
  • Meulenberg, J. J. M., Hulst, M. M., de Meijer, E. J., Moonen, P. L., den Besten, A., De Kluyver, E. P., Wensvoort, G., Moormann, R. J. (1993). Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virol. 192:62–72.
  • Meulenberg, J. J. M., Petersen-Den Besten, A., De Kluyver, E. P., Moormann, R. J. M., Schaaper, W.M.M., Wensvoort, G. (1995). Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus. Virol. 20:155–163.
  • Mingxiao, M., Ningyi, J., Juan, L. H., Min, Z., Guoshun, S., Guangze, Z., Huijun, L., Xiaowei, H., Minglan, J., Xu, L., Haili, M., Yue, J., Gefen, Y., Kuoshi, J. (2007). Immunogenicity of plasmids encoding P12A and 3C of FMDV and swine IL-18. Antiviral Res. 76:59–67.
  • Nguyen, Q. H., Roberts, R. L., Ank, B. J., Lin, S. J., Thomas, E. K., Stiehm, E. R. (1998). Interleukin (IL)-15 enhances antibody-dependent cellular cytotoxicity and natural killer activity in neonatal cells. Cell Immunol. 185:83–92.
  • Nimal, S., Heath, A. W., Thomas, M. S. (2006). Enhancement of immune responses to an HIV gp 120 DNA vaccine by fusion to TNF alpha cDNA. Vaccine 24:3298–308.
  • Osorio, F. A., Galeota, J. A., Nelson, E., Brodersen, B., Doster, A., Wills, R., Zuckermann, F., Laegreid, W. (2002). Passive transfer of virus-specific antibodies confers protection against reproductive failure induced by a virulent strain of porcine reproductive and respiratory syndrome virus and establishes sterilizing immunity. Virol. 302:9–20.
  • Ostrowski, M., Galeota, J. A., Jar, A. M., Platt, K. B., Osorio, F. A., Lopez, O. J. (2002). Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus GP5 ectodomain. J. Virol. 76, 4241–4250.
  • Pirzadeh, B., Dea, S. (1998). Immune response in pigs vaccinated with plasmid DNA encoding ORF5 of porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 79:989–999.
  • Plagemann, P. G. (2004). The primary GP5 neutralization epitope of North American isolates of porcine reproductive and respiratory syndrome virus. Vet. Immunol. Immunopathol. 102:263–275.
  • Ren, X., Wang, M., Yin, J., Ren, Y., Li G. (2010). Heterologous expression of fused genes encoding the glycoprotein 5 from PRRSV: a way for producing functional protein in prokaryotic microorganism. J. Biotechnol. 147:130–135.
  • Snijder, E. J., van Tol, H., Pedersen, K. W., Raamsman, M. J., de Vries, A. A. (1999). Identification of a novel structural protein of arteriviruses. J. Virol. 73:6335–6345.
  • Sonali, N., Andrew, W. H., Mark, S. T. (2006). Enhancement of immune responses to an HIV gp120 DNA vaccine by fusion to TNF alpha cDNA. Vaccine 24:3298–3308.
  • Sui, X., Yin, J., Ren, X. (2010). Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus. Antiviral Res. 85, 346–353.
  • Tagaya, Y., Bamford, R. N., DeFilippis, A. P., Waldmann, T. A. (1996). IL-5: a pleiotropic cytokine with diverse receptor:signaling pathways whose expression is controlled at multiple levels. Immunity 4: 329–336.
  • Tascon, R. E., Stavropoulos, E., Lukacs, K. V., Colston, M. J. (1998). Protection against Mycobacterum tuberculosis infection by CD8 T cells requires the production of gamma interferon. Infect. Immun. 66:830–834.
  • Tian, K., Yu, X., Zhao, T., Feng, Y., Cao, Z., Wang, C., Hu, Y., Chen, X., Hu, D., Tian, X., Liu, D., Zhang, S., Deng, X., Ding, Y., Yang, L., Zhang, Y., Xiao, H., Qiao, M., Wang, B., Hou, L., Wang, X., Yang, X., Kang, L., Sun, M., Jin, P., Wang, S., Kitamura, Y., Yan, J., Gao, G. F. (2007). Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark. PLoS One 2:e526.
  • Wang, M., Li, G., Yin, J., Ren, X. (2009). Phylogenetic characterization of genes encoding for glycoprotein 5 and membrane protein of PRRSV isolate HH08. J. Vet. Sci. 10:309–315.
  • Wensvoort, G., Terpstra, C., Pol, J. M. A., ter Laak, E. A., Bloemraad, M., de Kluyver, E. P., Kragten, C., van Buiten, L., den Besten, A., Wagenaar, F., Broekhuijsen, J. M., Moonen, P. L. J. M., Zetstra, T., de Boer, E. A., Tibben, H. J., de Jong, M. F., van’t Veld, P., Groenland, G. J. R., van Gennep, J.A., Voets, M. T. H., Verheijden, J. H. M., Braamskamp, J. (1991). Mystery swine disease in The Netherlands: the isolation of Lelystad virus. Vet. Q. 13:121–130.
  • Xiao. Z., Batista, L., Dee, S., Halbur, P., Murtaugh, M. P. (2004). The level of virus-specific T-cell and macrophage recruitment in porcine reproductive and respiratory syndrome virus infection in pigs is independent of virus load. J. Virol. 78:5923–5933.
  • Yang, L., Frey, M. L., Yoon, K. J., Zimmerman, J. J., Platt, K. B. (2000). Categorization of North American porcine reproductive and respiratory syndrome virus: epitopic profiles of the N M GP5 and GP3 proteins and susceptibility to neutralization. Arch. Virol. 145:1599–1619.
  • Yin, J., Dai, A., Laddy, D. J., Yan, J., Arango, T., Khan, A. S., Lewis, M. G., Andersen, H., Kutzler, M. A., Draghia-Akli, R., Weiner, D. B., Boyer, J. D. (2009). High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model. Virol. 393:49–55.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.