Publication Cover
Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 42, 2013 - Issue 8
200
Views
15
CrossRef citations to date
0
Altmetric
Research Article

Associations between interleukin-23R and interleukin-12B polymorphisms and psoriasis susceptibility: a meta-analysis

&
Pages 726-736 | Received 27 Apr 2013, Accepted 28 May 2013, Published online: 11 Jul 2013

References

  • Bhalerao J, Bowcock AM. (1998). The genetics of psoriasis: a complex disorder of the skin and immune system. Hum Mol Genet, 7, 1537–1545
  • Capon F, Di Meglio P, Szaub J, et al. (2007). Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet, 122, 201–206
  • Cargill M, Schrodi SJ, Chang M, et al. (2007). A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet, 80, 273–290
  • Davey Smith G, Egger M. (1997). Meta-analyses of randomised controlled trials. Lancet, 350, 1182
  • DerSimonian R, Laird N. (1986). Meta-analysis in clinical trials. Control Clin Trials, 7, 177–188
  • Di Cesare A, Di Meglio P, Nestle FO. (2009). The IL-23/Th17 axis in the immunopathogenesis of psoriasis. J Invest Dermatol, 129, 1339–1350
  • Duval S, Tweedie R. (2000). Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics, 56, 455–463
  • Egger M, Davey Smith G, Schneider M, Minder C. (1997a). Bias in meta-analysis detected by a simple, graphical test. BMJ, 315, 629–634
  • Egger M, Smith GD, Phillips AN. (1997b). Meta-analysis: principles and procedures. BMJ, 315, 1533–1537
  • Elder JT. (2009). Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis. Genes Immun, 10, 201–209
  • Filer C, Ho P, Smith RL, et al. (2008). Investigation of association of the IL12B and IL23R genes with psoriatic arthritis. Arthritis Rheum, 58, 3705–3709
  • Garcia VE, Chang M, Brandon R, et al. (2008). Detailed genetic characterization of the interleukin-23 receptor in psoriasis. Genes Immun, 9, 546–555
  • Higgins JP, Thompson SG. (2002). Quantifying heterogeneity in a meta-analysis. Stat Med, 21, 1539–1558
  • Huffmeier U, Lascorz J, Bohm B, et al. (2009). Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis. J Invest Dermatol, 129, 355–358
  • Lee YH, Witte T, Momot T, et al. (2005). The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: two case-control studies and a meta-analysis. Arthritis Rheum, 52, 3966–3974
  • Lee YH, Harley JB, Nath SK. (2006). Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility. Eur J Hum Genet, 14, 364–371
  • Litjens NH, van der Plas MJ, Ravensbergen B, et al. (2004). Psoriasis is not associated with IL-12p70/IL-12p40 production and IL12B promoter polymorphism. J Invest Dermatol, 122, 923–926
  • Liu Y, Helms C, Liao W, et al. (2008). A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet, 4, e1000041
  • Nair RP, Stuart PE, Nistor I, et al. (2006). Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. Am J Hum Genet, 78, 827–851
  • Nair RP, Ruether A, Stuart PE, et al. (2008). Polymorphisms of the IL12B and IL23R genes are associated with psoriasis. J Invest Dermatol, 128, 1653–1661
  • Nair RP, Duffin KC, Helms C, et al. (2009). Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet, 41, 199–204
  • Nair RP, Stuart PE, Kullavanijaya P, et al. (2010). Genetic evidence for involvement of the IL23 pathway in Thai psoriatics. Arch Dermatol Res, 302, 139–143
  • Safrany E, Szell M, Csongei V, et al. (2010). Polymorphisms of the IL23R gene are associated with psoriasis but not with immunoglobulin a nephropathy in a Hungarian population. Inflammation, 34, 603--608
  • Schlaak JF, Buslau M, Jochum W, et al. (1994). T cells involved in psoriasis vulgaris belong to the Th1 subset. J Invest Dermatol, 102, 145–149
  • Smith RL, Warren RB, Eyre S, et al. (2008). Polymorphisms in the IL-12beta and IL-23R genes are associated with psoriasis of early onset in a UK cohort. J Invest Dermatol, 128, 1325–1327
  • Tsunemi Y, Saeki H, Nakamura K, et al. (2002). Interleukin-12 p40 gene (IL12B) 3′-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris. J Dermatol Sci, 30, 161–166
  • Wu Y, Lu Z, Chen Y, et al. (2010). Replication of association between interleukin-23 receptor (IL-23R) and its ligand (IL-12B) polymorphisms and psoriasis in the Chinese Han population. Hum Immunol, 71, 1255–1258
  • Zhang XJ, Huang W, Yang S, et al. (2009). Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet, 41, 205–210
  • Zheng HF, Zuo XB, Lu WS, et al. (2011). Variants in MHC, LCE and IL12B have epistatic effects on psoriasis risk in Chinese population. J Dermatol Sci, 61, 124–128

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.