Immunological Approach of the Challenges of the XXI Century in Celiac Disease

REFERENCES

• Qiao SW, Iversen R, Ráki M, The adaptive immune response in celiac disease. Semin Immunopathol 2012;34:523–540.
   PubMed Web of Science ®Google Scholar
• Koning F. Celiac disease: quantity matters. Semin Immunopathol 2012;34:541–549.
   PubMed Web of Science ®Google Scholar
• Ráki M, Beitnes AC, Lundin KE, Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion. Mucosal Immunol 2013; (in press), doi: 10.1038/mi.2012.136. [Epub ahead of print].
   PubMedGoogle Scholar
• Dalleywater WJ, Chau DY, Ghaemmaghami AM. Tissue transglutaminase treatment leads to concentration-dependent changes in dendritic cell phenotype–implications for the role of transglutaminase in coeliac disease. BMC Immunol 2012;13:20, doi:10.1186/1471-2172-13-20.
   PubMedGoogle Scholar
• Broughton SE, Petersen J, Theodossis A, Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease. Immunity 2012;37:611–621.
   PubMed Web of Science ®Google Scholar
• Meresse B, Malamut G, Cerf-Bensussan N. Celiac disease: an immunological jigsaw. Immunity 2012;36:907–919.
   PubMed Web of Science ®Google Scholar
• Settakorn J, Leong AS. Immunohistologic parameters in minimal morphologic change duodenal biopsies from patients with clinically suspected gluten-sensitive enteropathy. Appl Immunohistochem Mol Morphol 2004;12:198–204.
   PubMedGoogle Scholar
• Leon F. Flow cytometry of intestinal intraepithelial lymphocytes in celiac disease. J Immunol Methods 2011;363:177–186.
   PubMed Web of Science ®Google Scholar
• Abadie V, Discepolo V, Jabri B. Intraepithelial lymphocytes in celiac disease immunopathology. Semin Immunopathol 2012;34:551–566.
   PubMed Web of Science ®Google Scholar
• Verbeek WH, Goerres MS, von Blomberg BM, Flow cytometric determination of aberrant intra-epithelial lymphocytes predicts T-cell lymphoma development more accurately than T-cell clonality analysis in Refractory Celiac Disease. Clin Immunol 2008;126:48–56.
   PubMed Web of Science ®Google Scholar
• Tjon JM, Kooy-Winkelaar YM, Tack GJ, DNAM-1 mediates epithelial cell-specific cytotoxicity of aberrant intraepithelial lymphocyte lines from refractory celiac disease type II patients. J Immunol 2011;186:6304–6312.
   PubMed Web of Science ®Google Scholar
• La Scaleia R, Barba M, Di Nardo G, Size and dynamics of mucosal and peripheral IL-17A +T-cell pools in pediatric age, and their disturbance in celiac disease. Mucosal Immunol 2012;5:513–523.
   PubMedGoogle Scholar
• Moens E, Veldhoen M. Epithelial barrier biology: good fences make good neighbours. Immunology 2012;135:1–8.
   PubMed Web of Science ®Google Scholar
• Hidaka M, Nakamura M, Ohmichi Y, Involvement of intestinal intraepithelial lymphocytes in turnover of intestinal epithelial cells: morphological and functional alterations due to daily administration of FK506. Cell Immunol 2012;279:124–133.
   PubMedGoogle Scholar
• Lindfors K, Koskinen O, Kaukinen K. An update on the diagnostics of celiac disease. Int Rev Immunol 2011; 30:185–196.
   PubMed Web of Science ®Google Scholar
• Lindfors K, Mäki M, Kaukinen K. Transglutaminase 2-targeted autoantibodies in celiac disease: pathogenetic players in addition to diagnostic tools? Autoimmun Rev 2010;9:744–749.
   PubMed Web of Science ®Google Scholar
• Bonaci-Nikolic B, Andrejevic S, Radlovic N, Serological and clinical comparison of children and adults with anti-endomysial antibodies. J Clin Immunol 2007; 27:163–171.
   PubMedGoogle Scholar
• Tosco A, Aitoro R, Auricchio R, Intestinal anti-tissue transglutaminase antibodies in potential coeliac disease. Clin Exp Immunol 2013; 171:69–75.
   PubMed Web of Science ®Google Scholar
• Volta U, Villanacci V. Celiac disease: diagnostic criteria in progress. Cell Mol Immunol 2011;8:96–102.
   PubMed Web of Science ®Google Scholar
• Presani G, Perticarari S, Mangiarotti MA. Flow cytometric detection of anti-gliadin antibodies. J Immunol Methods 1989;119:197–202.
   PubMedGoogle Scholar
• Wolters VM, Alizadeh BZ, Weijerman ME, Intestinal barrier gene variants may not explain the increased levels of antigliadin antibodies, suggesting other mechanisms than altered permeability. Hum Immunol 2010;71:392–396.
   PubMedGoogle Scholar
• Samaşca G, Iancu M, Băican A, Romanian experience in child celiac disease diagnosis. Roum Arch Microbiol Immunol 2011;70:178–185.
   PubMedGoogle Scholar
• Lindfors K, Koskinen O, Kurppa K, Serodiagnostic assays for celiac disease based on the open or closed conformation of the autoantigen, transglutaminase 2. J Clin Immunol 2011;31: 436–442.
   PubMed Web of Science ®Google Scholar
• Rozenberg O, Lerner A, Pacht A, A novel algorithm for the diagnosis of celiac disease and a comprehensive review of celiac disease diagnostics. Clin Rev Allergy Immunol 2012;42:331–341.
   PubMed Web of Science ®Google Scholar
• Prince HE. Evaluation of the INOVA diagnostics enzyme-linked immunosorbent assay kits for measuring serum immunoglobulin G (IgG) and IgA to deamidated gliadin peptides. Clin Vaccine Immunol 2006;13:150–151.
   PubMedGoogle Scholar
• Ankelo M, Kleimola V, Simell S, Antibody responses to deamidated gliadin peptide show high specificity and parallel antibodies to tissue transglutaminase in developing coeliac disease. Clin Exp Immunol 2007;150:285–293.
   PubMed Web of Science ®Google Scholar
• de Kauwe AL, Chen Z, Anderson RP, Resistance to celiac disease in humanized HLA-DR3-DQ2-transgenic mice expressing specific anti-gliadin CD4+ T cells. J Immunol 2009;182:7440–7450.
   PubMed Web of Science ®Google Scholar
• Petersen NH, Hansen PR, Houen G. Fast and efficient characterization of an anti-gliadin monoclonal antibody epitope related to celiac disease using resin-bound peptides. J Immunol Methods 2011;365:174–182.
   PubMed Web of Science ®Google Scholar
• Rauhavirta T, Qiao SW, Jiang Z, Epithelial transport and deamidation of gliadin peptides: a role for coeliac disease patient immunoglobulin A. Clin Exp Immunol 2011;164:127–136.
   PubMed Web of Science ®Google Scholar
• Wang N, Hammarström L. IgA deficiency: what is new? Curr Opin Allergy Clin Immunol 2012;12:602–608.
   PubMed Web of Science ®Google Scholar
• Agarwal S, Mayer L. Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes. J Allergy Clin Immunol 2009;124:658–664.
   PubMedGoogle Scholar
• Valletta E, Fornaro M, Pecori S, Selective immunoglobulin A deficiency and celiac disease: let's give serology a chance. J Investig Allergol Clin Immunol 2011;21:242–244.
   PubMed Web of Science ®Google Scholar
• Dostal A, Linnankivi T, Somer M, Mapping susceptibility gene locus for IgA deficiency at del(18)(q22.3-q23); report of familial cryptic chromosome t(18q; 10p) translocations. Int J Immunogenet 2007;34:143–147.
   PubMed Web of Science ®Google Scholar
• Borrelli M, Maglio M, Agnese M, High density of intraepithelial gammadelta lymphocytes and deposits of immunoglobulin (Ig)M anti-tissue transglutaminase antibodies in the jejunum of coeliac patients with IgA deficiency. Clin Exp Immunol 2010;160:199–206.
   PubMedGoogle Scholar
• Alaedini A, Green PH. Autoantibodies in celiac disease. Autoimmunity 2008;41:19–26.
   PubMed Web of Science ®Google Scholar
• Myrsky E, Kaukinen K, Syrjänen M, Coeliac disease-specific autoantibodies targeted against transglutaminase 2 disturb angiogenesis. Clin Exp Immunol 2008;152:111–119.
   PubMed Web of Science ®Google Scholar
• Ferrara F, Quaglia S, Caputo I, Anti-transglutaminase antibodies in non-coeliac children suffering from infectious diseases. Clin Exp Immunol 2010;159:217–223.
   PubMed Web of Science ®Google Scholar
• Granito A, Muratori P, Cassani F, Anti-actin IgA antibodies in severe coeliac disease. Clin Exp Immunol 2004;137:386–392.
   PubMed Web of Science ®Google Scholar
• Samaşca G, Băican A, Pop T, IgG-F-actin antibodies in celiac disease and dermatitis herpetiformis. Roum Arch Microbiol Immunol 2010;69:177–182.
   PubMedGoogle Scholar
• Mawhinney H, Love AH. Anti-reticulin antibody in jejunal juice in coeliac disease. Clin Exp Immunol 1975; 21:394–398.
   PubMed Web of Science ®Google Scholar
• Unsworth DJ, Scott DL, Walton KW, Failure of R1 type anti-reticulin antibody to react with fibronectin, collagen type III or the non-collagenous reticulin component (NCRC). Clin Exp Immunol 1984; 57:609–613.
   PubMed Web of Science ®Google Scholar
• Lock RJ, Gilmour JE, Unsworth DJ. Anti-tissue transglutaminase, anti-endomysium and anti-R1-reticulin autoantibodies-the antibody trinity of coeliac disease. Clin Exp Immunol 1999;116:258–262.
   PubMed Web of Science ®Google Scholar
• Shaoul R, Lerner A. Associated autoantibodies in celiac disease. Autoimmun Rev 2007;6:559–565.
   PubMed Web of Science ®Google Scholar
• Nandiwada SL, Tebo AE. Testing for anti-reticulin antibodies in celiac disease is obsolete: a review of recommendations for serologic screening and the literature. Clin Vaccine Immunol 2013;20:447–451.
   PubMed Web of Science ®Google Scholar
• Malamut G, Meresse B, Cellier C, Refractory celiac disease: from bench to bedside. Semin Immunopathol 2012;34:601–613.
   PubMedGoogle Scholar
• McAllister CS, Kagnoff MF. The immunopathogenesis of celiac disease reveals possible therapies beyond the gluten-free diet. Semin Immunopathol 2012;34:581–600.
   PubMed Web of Science ®Google Scholar
• Sánchez D, Palová-Jelínková L, Felsberg J, Anti-calreticulin immunoglobulin A (IgA) antibodies in refractory coeliac disease. Clin Exp Immunol 2008;153:351–359.
   PubMed Web of Science ®Google Scholar
• Manavalan JS, Hernandez L, Shah JG, Serum cytokine elevations in celiac disease: association with disease presentation. Hum Immunol 2010;71:50–57.
   PubMed Web of Science ®Google Scholar
• Verbeek WH, Schreurs MW, Visser OJ, Novel approaches in the management of refractory celiac disease. Expert Rev Clin Immunol 2008;4:205–219.
   PubMed Web of Science ®Google Scholar
• Yokoyama S, Perera PY, Waldmann TA, Tofacitinib, a janus kinase inhibitor demonstrates efficacy in an IL-15 transgenic mouse model that recapitulates pathologic manifestations of celiac disease. J Clin Immunol 2012;33:586–594.
   PubMed Web of Science ®Google Scholar