Antioxidants in the Prevention of Renal Disease

References

• Palmer R J. Reactive oxygen species and antioxidants in signal transduction and gene expression. Nutr Revs 1997; 55: 353–61
   PubMed Web of Science ®Google Scholar
• Baliga R, Veda N, Shah S V. Oxidant meehanisms in Glomerular Disease. in Current Nephrology, H C Gonick. Year Book Inc., Mosby 1997; Chap 4: 135–151
   Google Scholar
• Diamond J R. Reactive oxygen species and progressive glomerular disease. Lab Invent 1994; 124: 468–469
   Google Scholar
• Johnson R J, Lovett D, Lehrer R I, Couser W G, Klebanoff S J. Role of oxidanls and proteases in glomerular injury. Kidney Int 1994; 45: 352–359
   PubMed Web of Science ®Google Scholar
• Shah S V. Role of reactive oxygen metabolites in experimental glomerular disease. Kidney Int 1989; 35: 1093–1106
   PubMed Web of Science ®Google Scholar
• Paller M S, Hoidal J R, Ferris T F. Oxygen free radicals in ischemie acute renal failure in the rat. J Clin Invest 1984; 74: 1156–1164
   PubMed Web of Science ®Google Scholar
• Poli G, Parola M. Oxidattve damage and fibrogenesis. Free Radical Biol Med 1997; 22: 287–305
   PubMed Web of Science ®Google Scholar
• Young M R, Young I S, Johnston S R, Rowlands B J. Lipid peroxidation assessment of free radical production follow ing release of obstructive uropathy. J Urology 1996; 156: 1828–1832
   PubMed Web of Science ®Google Scholar
• Wu S M, Patel D D, Pizzo S V. Oxidised α2-macroglobulin differentially regulates receptor binding by cytokines/growth factors: implications for tissue injury and repair mechanisms in inflammation. J Immunology 1998; 161: 4356–4361
   PubMed Web of Science ®Google Scholar
• Barnes P J. Nuclear factor-kB. Int. J Biochem 1997; 29: 867–870
   Google Scholar
• Irani K, Goldschmidt-Clermont P J. Ras, superoxide and signal transduction. Biochem Pharmacol 1998; 55: 1339–1346
   PubMed Web of Science ®Google Scholar
• Halliwell B. Antioxidants: the basics - what they are and how to evaluate them. Chap 1 in Antioxidants in Disease: Mechanisms and Therapy. Ed H Sies. Adv Pharmacology 1997; 38: 3–20
   PubMedGoogle Scholar
• Freeman B A, Crapo J D. Biology of disease: Free radicals andtissue injury. Lab Invest 1982; 47: 412–426
   PubMed Web of Science ®Google Scholar
• Nath K A, Fischereder M, Hostetter T H. The role of oxidanls in progressive renal injury. Kidney Int 1994; S45: S111–S115
   Google Scholar
• Adler S, Baker P J, Johnson R J, Ochi R F, Pritzl P, Couser W G. Complement membrane attack complex stimulates production of ROIs by cultured mesangial cells. J Clin Invest 1986; 77: 762–767
   PubMed Web of Science ®Google Scholar
• Futsakul P, Sitprija V, Yenrudi S, Poshyachinda M, Sensirivatana R, Watana D, Singklura V, Jungthirapanich J, Futrakul N. Glomerular endothelial dysfunction determines disease progression: hypothesis. Amer J Nephrology 1997; 17: 533–540
   PubMed Web of Science ®Google Scholar
• Tay M, Commer W S, Vassiliou P. The inhibitory action of oxygen radical scavengers on proteinuria and glomerular heparan sulphate loss in the isolated perfused kidney. Biochem Int 1990; 20: 767–78
   PubMedGoogle Scholar
• Rohn T T, Nelson L K, Sipes K, Swain S D, Jutila K L, Quinn M T. Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response. J Leuko Biol 1999; 65: 59–70
   PubMed Web of Science ®Google Scholar
• Kerjaschki D. Epitopes and radicals: early events in glomerular injury in membranous nephropathy. Exp Nephrology 1995; 3: 1–8
   PubMedGoogle Scholar
• Berliner J V, Heineeke J W. Role of oxidised lipoproteins in atherogenesis. Free Radical Biol Med 1996; 29: 707–27
   Google Scholar
• Malle E, Woenckhaus C, Waeg G, Fsterbauer H, Grone E F, Grone H J. Immunologie evdience for hypochlorite mediated proteins in human kidney. Amer J Pathol 1997; 150: 603–615
   PubMed Web of Science ®Google Scholar
• Guijaaro C, Keane W F. Lipid induced glomerular injury. Nephron 1994; 67: 1–6
   PubMed Web of Science ®Google Scholar
• Sugiyama H, Kashihara N, Makino H, Yamasaki Y, Ola Z. Reactive oxygen species induce apoptosis in cultured human mesangial cells. J Amer Soc Nephrology 1996; 7: 2357–2363
   PubMed Web of Science ®Google Scholar
• McCord J M. Superoxide radical: controversies, contradictions and paradoxes. Proc Soc Exp Biol Med 1995; 209: 112–17
   PubMed Web of Science ®Google Scholar
• Yokoo T, Kitamura M. II-1 depresses expression of the 70 kD HSP and sensitizes glomerular cells to oxidant initialed apoptosis. J Immunology 1997; 159: 2886–2892
   PubMed Web of Science ®Google Scholar
• Feranes R S, Cotter T G. Apoptosis and necrosis: intracellular levels of glutathione influence mode of cell death. Biochem Pharmacol 1996; 48: 675–81
   Web of Science ®Google Scholar
• Sandstrotn P A, Pardi D, Tebbey P W, Dudek R W, Terranian D M, Folks T M, Buttke T N. Lipid hydroperoxide induces apoptosis: lack of inhibition by bcl-2 expression. FEBS Len 1996; 365: 66–70
   Web of Science ®Google Scholar
• Halliwell B. Antioxidants in human health and disease. Ann Review Nutrition 1996; 16: 33–50
   PubMed Web of Science ®Google Scholar
• Block G, Patterson E, Subar A. Fruit, vegetables and cancer prevention. Nutr Cancer 1992; 29: 1–19
   Google Scholar
• O'Brien P J. Antioxidants and cancer: molecular mechanisms. Adv Exp Med Biol 1994; 366: 215–239
   PubMedGoogle Scholar
• Verhagen H, Poulsen H E, Loft S, van Poppel G, Willems M I, van Bladcren P J. Reduction of oxidative DNA damage in humans by brussel sprouts. Carcinogenesis 1995; 16: 969–970
   PubMed Web of Science ®Google Scholar
• Ursini F, Bindoli A. The role of selenium peroxidases in protection against oxidative damage of membranes. Chem Physics Lipids 1987; 44: 255–276
   PubMed Web of Science ®Google Scholar
• Buring J E, Hennekens C H. Antioxidant vitamins and cardiovascular disease. Nutrition Revs 1997; 55: 553–558
   Web of Science ®Google Scholar
• Lapenna D, deGioia S, Ciofani H, Cuccurollo F. Antioxidant activity of allopurinol on copper catalysed human lipoprotem oxidation. FEBS Lett 1997; 409: 265–268
   PubMed Web of Science ®Google Scholar
• Heitzer T, Just H, Munzel T. Antioxidant vitamin C improves endothclial dysfunction in chronic smokers. Circulation 1996; 94: 6–9
   PubMed Web of Science ®Google Scholar
• Khan N S, Sooranna S R. Potent activation of nitric oxide synthase by garlic: basis for its therapeutic applications. Current Medical Research Opinion 1995; 13: 257–263
   PubMed Web of Science ®Google Scholar
• Prasad K, Laxdal V A, Yu M, Raney B L. Evaluation of hydroxy-radiical scavenging proprty of garlic. Mol Cell Biochem 1996; 154: 55–63
   PubMed Web of Science ®Google Scholar
• Ichikawa I, Kiyama S, Yoshioka T. Renal antioxidant enzymes: their generation and function. Kidney Int 1994; 45: 1–9
   PubMed Web of Science ®Google Scholar
• Zurovsky Y, Haber C. Antioxidants allenuate endoloxin-gentamicin induced acute renal failure in rats. Scand J Crol Nephrol 1995; 29: 147–154
   PubMed Web of Science ®Google Scholar
• Beaman M, Birtwistle R, Howie A J, Michael J, Adu D. The role of superoxide anion and hydrogen peroxide in glomerular injury induced by puromycin aminonucleoside in rats. Clinical Science 1987; 73: 329–332
   Web of Science ®Google Scholar
• Chubatsu L S, Meneghini R. Metallothionein protects DNA from oxidative damage. Biochem J 1993; 291: 193–198
   PubMed Web of Science ®Google Scholar
• Peuchant E, Delmas N, Beauvieux M C, Dubourg L, Thomas M J, Perromat A, Apariclo M, Clara M, Combe C. Antioxidant effects of supplemented very low protein diet. Free Rad Biol Med 1997; 22: 313–320
   PubMed Web of Science ®Google Scholar
• Schreck R, Meier B, Manuel D M, Droge W, Bauerle P A. Dithiocarbamates as potent inhibitors of NF-kB activation in intact cells. J Exp Med 1992; 175: 1181–1194
   PubMed Web of Science ®Google Scholar
• Hecker M, Preiss C, Kleman P, Bttsse R. Inhibition by antioxidants of nitric oxide synthase expression in murine macrophages: role of NF-kB and IRF-1. Brit J Pharmacol 1996; I 18: 2178–2184
   Google Scholar
• Tetsuka T, Baier L D, Morrison A R. Antioxidants inhibit Il-1 induced cyclooxygenase and nitric oxide synthase expression in rat mesangial cells. J Biol Chem 1966; 271: 11689–11693
   Google Scholar
• Sato M, Miyazaki T, Nagaya T, Murata Y. Antioxidants inhibit TNFa mediated stimulation of I1-8, MCP-1 and collagenase in cultured human synovial cells. J Rheumatology 1996; 23: 432–438
   PubMed Web of Science ®Google Scholar
• Eugui E M, De Lustro B, Rouhafza S, Ilnicka M, Lee S W, Wilhem R, Allison A C. Some antioxidants inhibit in a coordinate fashion the production of TNFa, I1-1 and I1-6 by human peripheral blood mononuclear cells. Int Immunol 1994; 6: 409–422
   PubMed Web of Science ®Google Scholar
• Allison A C. Antioxidant drug targeting In Antioxidants in Disease: Mechanisms and Therapy. Ed H Sies. Adv Pharmacology 1977; 38: 273–290
   Google Scholar
• Lehr H A, Meesmer K. Rationale for the use of antioxidant vitamins in clinical organ transplantation. Transplantation 1996; 62: 1197–1199
   PubMed Web of Science ®Google Scholar
• Salahudeen A, Wang C, McDaniel O, Lagoo-Denodyalan S, Bigler S, Barber H. Antioxidant lazaroid U-74006F improves renal function and reduces expression of cytokines, inducible nitric oxide synthase and MHC antigens in a syngeneic renal transplant model. Transplantation 1996; 62: 1623–1633
   Web of Science ®Google Scholar
• Remick D G, Villaretti L. Regulation of cytokine gene expression by reactive oxygen and reactive nitrogen intermediates. J Leukocyte Biol, 59: 421–425
   Web of Science ®Google Scholar
• Parra T, de Arriba G, Conejo G, Conejo J R, Cantero M, Arribas I, Rodriguez-Puyol D, Rodriguez-Puyol M, Carballo F. Cyclosporin increases local glomerular synthesis of reactive oxygen species in rats:effect of vitamin E. Transplantation 1998; 66: 1325–1329
   PubMed Web of Science ®Google Scholar
• Raschke P, Massoudy P, Becker B F. Taurine protects the heart from neutrophil induced reperfusion injury. Free Radical Biol Med 1995; 19: 461–457
   PubMed Web of Science ®Google Scholar
• Cotgreave I A. N-acetylcysteine: pharmacological considerations and experimental and clinical applications. Adv Pharmacology 1997; 38: 205–227
   PubMedGoogle Scholar
• Mannhardt W, Putzer M, Zepp F, Schulte-Wissermann H. Host defense within the urinary tract. II: Signal transducing events activate the uroepithelial defense. Pediatr Nephrol 1996; 10: 573–577
   PubMed Web of Science ®Google Scholar
• Di Gianni P, Minnucci F S, Alves R, Osa MF, Vulcano M, Isturiz M A. Antioxidants inhibit the enhancement of the immune response caused by oil adjuvants. Scand J Immunol 1996; 43: 413–420
   PubMed Web of Science ®Google Scholar
• Gomez del Arco P, Martinez-Martinez S, Calvo V, Armesilia A L, Redondo J. JNK is a target for antioxidants in T lymphocytes. J BiolChem 1996; 271: 26335–40
   PubMed Web of Science ®Google Scholar
• De L A, Fuente M, Ferrandez M D, DelRio M, SolBurgos M, Miguel J. Enhancement of leukocyte functions in aged mice supplemented with the antioxidant thioproline. Mech Age Development 1998; 104: 213–25
   PubMed Web of Science ®Google Scholar
• Blackwell T S, Blackwell T R, Holden E P, Christman B W, Christman J W. In vivo antioxidant treatment suppresses NF-kB activation and neutrophilic lung inflammation. J Immunol 1996; 157: 1630–1637
   PubMed Web of Science ®Google Scholar
• Springer T A. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Ann Rev Physiol 1995; 57: 827–72
   PubMed Web of Science ®Google Scholar
• Ferran C, Millan M T, Csizmadia V, Cooper J T, Brostjan C, Bach F H, Winkler H. Inhibition of NF-kB by pyrrolidine dithiocarbamate blocks endothelial cell activation. Biochem Biophys Res Comm 1995; 214: 212–223
   PubMed Web of Science ®Google Scholar
• Khachigian L M, Collins T, Fries J WU. N-acetylcysleine blocks mesangial VCAM-1 and NF-kB expression. Am J Path 1997; 151: 1225–1230
   PubMed Web of Science ®Google Scholar
• Gerritsen M E, Carley W W, Ranges G E, Shen C P, Phan S A, Ligand G F, Perry C A. Flavanoids inhibit cytokine induced endothelial cell adhesion protein gene expression. AmerJ Pathol 1995; 147: 278–292
   PubMed Web of Science ®Google Scholar
• Seljetlot I, Arensen H, Brude I R, Nenseter M S, Drevan C A, Hjermann I. Effect of ω-3 fatty acids and/or antioxidants on endothelial cell markers. Eur J Clin Invest 1998; 28: 629–635
   PubMed Web of Science ®Google Scholar
• Cominocini L, Garbin U, Pasini A F, Davioli A. Antioxidants inhibit the expression of ICAM-1 and VCAM-1 induced by oxidised LDL on human umbilical vein cells. Free Rad Biol Med 1997; 22: 117–127
   PubMed Web of Science ®Google Scholar
• Holt S, Goodier D, Marley R, Patel D, Burroughs A, Fernando E, Harry D, Moore K. Improvement in renal function in hepato-renal syndrome with N-acetylcysteine. Lancet 1999; 353: 294–5
   PubMed Web of Science ®Google Scholar
• Miller D D, Edwards A. Food antioxidants. in Encyclopaedia of Human Biology, Dulbecco R. Academic Press. 1997; vol 4: 43–54
   Google Scholar
• Zcng L-H, Fung K-P, Wu T-W. Morin hydrate protects cultured rat glomerular mesangial cells against oxyradical damage. Life Science 1994; 55: 351–357
   PubMed Web of Science ®Google Scholar
• Veroart L, Ronden J E, Thijssen H. The potent antioxidant activity of the vitamin K cycle in microsomal lipid peroxidation. Biochem Pharmacol 1997; 54: 871–876
   PubMed Web of Science ®Google Scholar
• Potter S M. Soy protein and cardiovascular disease. Nutrition Reviews 1998; 56: 231–235
   PubMed Web of Science ®Google Scholar
• Wardle E N. Soyprotein diet therapy in renal disease. Nephron 1998; 78: 328–331
   PubMed Web of Science ®Google Scholar
• Wei H, Bowden R, Cai O, Barnes S, Wang Y. Antioxidant and antipromotional effects of the soybean isoflavone genistein. Proc Soc Exp Biol Med 1995; 208: 124–130
   PubMed Web of Science ®Google Scholar
• Mitchell S H, Gardner P T, McPhail D E, Morrice P C, Collins A R, Duthie G G. Antioxidant efficacy of phytoestrogens in chemical and biological model systems. Arch Biochem Biophys 1998; 360: 142–148
   PubMed Web of Science ®Google Scholar
• Tham D M, Gardner C D, Haskell W L. Potential health benefits of dietary phytoestrogens. J Cin End Metab 1998; 83: 2223–2234
   PubMed Web of Science ®Google Scholar
• Wiseman H, Plitzanopoulos P, O'Reilly J. Antioxidant properties of ethanolic and aqueous extracts of green tea compared to black tea. Biochem Soc Trans 1996; 24: 390S
   Web of Science ®Google Scholar
• Sanbongi C, Suzuki N, Sakana T. Polyphenols in chocolate, which has antioxidant activity, modulate immune function in human in vitro. Cell Immunology 1997; 177: 129–136
   PubMed Web of Science ®Google Scholar
• Petroni A. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil. Thrombos Res 1995; 78: 151–160
   PubMed Web of Science ®Google Scholar
• de la Puerta R, Gutierrez V R, Hoults S HS. Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil. Biochem Pharmacol 1999; 57: 445–449
   PubMed Web of Science ®Google Scholar
• Simopoulos A P, Norman H A, Gillaspy S E. Purslane in human nutrition and its potential for world agriculture. Plants in Human Nutrition. World Rev Nutr Diet, A P Simopoulos. Karger. 1995; 77: 47–74
   Google Scholar
• Chen S D, Wu Y-Z, Tao Z L, Chen Z M, Liu X P. Hawthorn drink and its lowering effect on blood lipid levels in humans and rats. World Rev Nutr Diet, A P Sinopoulos. Karger. 1995; 77: 147–154
   Google Scholar
• Roback J, Gryglewski R J. Bioactivity of Flavanoids. Polish J Pharmacol 1996; 48: 555–564
   PubMedGoogle Scholar
• Chen Z Y. Antioxidant activity of natural flavanoids is goverened by number and location of their aromatic hydroxy-groups. Chem Phys Lipids 1996; 79: 157–163
   PubMed Web of Science ®Google Scholar
• Greenspan H C, Aruoma O I. Oxidative stress and apoptosis in HIV infection. Immunology Today 1994; 15: 209–13
   PubMedGoogle Scholar
• Vinson S A. Fiavanoids in foods as in vitro and in vivo antioxidants. Adv Exp Med Biol 1998; 439: 151–164
   PubMed Web of Science ®Google Scholar
• Velussi M, Cemigoi A M, DeMonte A, Dapas F, Caffau C, Zilli M. Long term treatment with antioxidant drug silymarin in cirrhotic diabetic patients. J Hepatology 1997; 26: 871–879
   PubMed Web of Science ®Google Scholar
• Chaurasia S. Antioxidant and antiinflammatory action of Sandhika: a compound herbal drug. Indian J Exp Bilo 1995; 33: 428–436
   PubMedGoogle Scholar
• Sundaram V, Hanna A N, Lubow C P, Koneru L, Falko J M, Sharma H M. Inhibition of LDL oxidation by oral herbal mixtures in hyperlipidemic patients. Amer J Med Sci 1997; 314: 303–10
   PubMed Web of Science ®Google Scholar
• Agarwal S, Rao A V. Tomato lycopene and LDL oxidation: a human dietary intervention study. Lipids 1998; 33: 981–984
   PubMed Web of Science ®Google Scholar
• Rao A V, Agarwal S. Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer. Nutrition & Cancer 1998; 31: 199–203
   PubMed Web of Science ®Google Scholar
• Cao G, Russell R M, Lischner N, Prior R L. Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women. J Nutrition 1998; 128: 2383–2390
   PubMed Web of Science ®Google Scholar
• Xu Y X, Pindolia K R, Janakiraman N, Noth C J, Chapman R A, Gautam S C. Curcumin a compound with antiinflammatory and antioxidant properties downregulates chemokine expression in bone marrow stromal cells. Exp Haematol 1997; 25: 411–422
   Google Scholar
• Beukleman C J, van den Berg A J, Kroes B H, Labadie R P, Mattson E E, van Dijk H. Plant derived metabolites with synergistic antioxidant activity. Immunology Today 1995; 16: 108
   Google Scholar
• Trachtman H, Del Pizzo R, Futterweit S, Levine D, Rao P S, Valdenrama E, Sturm J A. Taurine attenuates renal disease in chronic puromycin aminonucleoside nephropathy. Am J Physiol 1992; 262: 117–123
   Google Scholar
• Denis M. Antioxidant therapy partially blocks immune induced lung fibrosis. Inflammation 1995; 19: 207–219
   PubMed Web of Science ®Google Scholar
• Schlotte V, Sevanian A, Hochstcin P, Weithmann K V. Effect of uric acid and chemical analogues on oxidation of human LDL. in vitro. Free Rad Biol Med 1998; 25: 839–847
   PubMed Web of Science ®Google Scholar
• Sanaka T, Nakano Y, Nishimura H, Shinobe M, Higuchi C, Omata M, Nihei H, Sugino H. Therapeutic effect of a newly developed antioxidative agent OPC-15161 on experimental immune complex nephritis. Nephron 1997; 76: 315–322
   PubMed Web of Science ®Google Scholar
• Toffer M, Mohsen M, Samuni A A. Superoxide dismutase mimicry underlies the role of nitroxides in protecting papain from oxidative inactivation. Free Rad Biol Med 1998; 25: 832–838
   PubMed Web of Science ®Google Scholar
• van der Zee J, Eling T E, Mason R P. Formation of free radical metabolites in the reaction between soybean lipoxygenase and its inhibitors. Biochemistry 1989; 28: 8363–8367
   PubMed Web of Science ®Google Scholar
• Garvin P J, Niehoff M L, Robinson S M, Mistry P. Renoprotective effects of the 21 aminosteroid U74389G in ischemia-reperfusion injury and cold storage preservation. Transplant 1997; 63: 194–201
   PubMed Web of Science ®Google Scholar
• Remmers D, Dwenger A, Grotz M, Seekamp A, Pap H C, Gruner A, Hafemann R, Regel G. Attenuation of multiple organ dysfunction in a chronic sheep model by 21 aminosteroid U74389 G. J Surg Res 1996; 62: 278–283
   PubMed Web of Science ®Google Scholar
• Batna A, Fuchs C, Spiteller C. Lipid peroxides in presence of ebselen. Chem Phys Lipids 1997; 87: 149–158
   PubMed Web of Science ®Google Scholar
• Lubec B, Aufricht C, Amman G, Kitzmuller E, Hoger H. Arginine reduces kidney collagen accumulation, crosslinking lipid peroxidation, glycoxidation, kidney weight and albuminuria in the diabetic kk mouse. Nephron 1997; 75: 213–218
   PubMed Web of Science ®Google Scholar
• Novelli G P, Casali R, Bonizzoli M, Giorgi L, Lemma M, Piseitelli P. Antioxidative action of gabexate mesilate in an experimental model of endotoxin shock. Minerva Anaesthesiol 1995; 61: 509–513
   PubMedGoogle Scholar
• Reibnegger G, Oettl K, Dlikalov S, Freisleben H J, Mickusch W. Spin trapping study of antioxidant properties of neopterin 7,8 dihydroneopterin. Biochim. Biophys Res Comm 1997; 234: 774–778
   PubMed Web of Science ®Google Scholar
• Thresiamma K C, Kuttan R. Inhibition of liver fibrosis by ellagic acid. Indian J Physiol Pharmacol 1996; 40: 363–366
   PubMedGoogle Scholar
• Magil A. Inhibition of progression of chronic puromycin aminonucleoside nephrosis by probucol. JAS Nephrol 1996; 7: 2340–2347
   Web of Science ®Google Scholar
• Keaney J F, Xu A, Cunningham D, Jackson T, Frei B, Vita J A. Dietary Probucol preserves endothelial cell function in cholesterol fed rabbits limiting vascular oxidative stress and superoxide generation. J Clin Invest 1995; 95: 2520–2529
   PubMed Web of Science ®Google Scholar
• Naito H, Hirano T. Probucol suppresses development of chronic renal failure in Dahl salt sensitive rat: an animal model of spontaneous focal and segmental glomerulosclerosis. Nephron 1994; 67: 125–126
   PubMed Web of Science ®Google Scholar
• Hanna A N, Feller D R, Witiak D T, Newman H. Inhibition of LDL oxidation by thyronines and probucol. Bioch. Pharmacol 1993; 45: 753–762
   PubMed Web of Science ®Google Scholar
• Igawa K, Maruyama R, Katayama I M, Nishioka K. Antioxidation therapy with oral dapsone improved annular elastolytic giant cell granuloma. J Dermatol 1997; 24: 328–331
   PubMedGoogle Scholar
• Hoffbrand B I. Dapsone treatment for Henoeh-Schönlein purpura. Postgrad Med J (UK) 1991; 67: 961–962
   PubMed Web of Science ®Google Scholar
• Campbell R K. Clinical update on pentoxifylline therapy for diabetes induced peripheral vascular disease. Ann Pharmacoi 1993; 27: 1099–1105
   PubMed Web of Science ®Google Scholar
• Mandy Y, Farkas G, Ocsovszky I, Nagy Z. Inhibition of TNFa production and ICAM-1 expression by pentoxifylline: beneficial effects in sepsis syndrome. Res Exptl Med 1995; 195: 297–307
   PubMedGoogle Scholar
• Wardle E N. Can pentoxifylline prevent renal disease?. Renal Failure 1998; 20: 437–440
   PubMed Web of Science ®Google Scholar
• Iuliano L, Colavita A R, Camastra C, Bello V. Protection of IDL oxidation at chemical and cellular level by the antioxidant drug dipyridamole. Brit J Pharmacol 1996; 119: 1438–1446
   PubMed Web of Science ®Google Scholar
• Wardle E N. Dipyridamole in the nephritides. Am J Therap 1998; 5: 107–109
   PubMedGoogle Scholar
• Grant D, Long W F, Mackintosh G, Williamson F B. The antioxidant activity of heparins. Biochem Soc Trans 1996; 24: 1948
   Google Scholar
• Wardle E N. Heparins for proliferative nephritides. Nephron 1996; 73: 515–19
   PubMed Web of Science ®Google Scholar
• Aruoma O I, Smith C, Cecchini R, Evans P J, Halliwell B. Free radical scavenging and inhibition of lipid peroxidation by beta-blockers and by agents that interfere with calcium metabolism. Biochem Pharmacol 1991; 42: 735–743
   PubMed Web of Science ®Google Scholar
• Dupont A G. Carvedilol and the kidney. Clinical Investigation 1992; 70: S127–S131
   PubMedGoogle Scholar
• Yue T-L, Cheng H-Y, Lysko P G, McKenna P J, Feuerstein R, Gu J-L, Lysko K. Carvedilol, a new vasodilator and adrenoreceptor antagonist is an antioxidant and free radical seavneger. J Pharm Exp Therap 1992; 263: 92–98
   PubMed Web of Science ®Google Scholar
• Kramsch D M, Sharma R C. The benefits amlodipine as an anti-atherosclerotic agent. J Human Hypertension 1995; 9(suppl 1): S3–S9
   Web of Science ®Google Scholar
• Sugawara H, Tobise K, Kikuchi K. Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation. Hypertension Res 1996; 19: 223–228
   PubMedGoogle Scholar
• Mak I T, Boehme P, Weglicki W B. Protective effects of calcium channel blockers against free radical impaired endothelial cell proliferation. Biochem Pharmacol 1995; 50: 1531–1534
   PubMed Web of Science ®Google Scholar
• Karmansky I, Gruener N A. Mechanisms of antioxidant activity of calcium antagonist verapamil against LDL, oxidation. Clin Chem Acta 1997; 259: 177–182
   PubMed Web of Science ®Google Scholar
• Chaffman M. Indapamide. Drugs 1984; 28: 189–235
   PubMed Web of Science ®Google Scholar
• Aruoma O I. Characterization of drugs as antioxidant prophylactics. Free Rad Biol Med 1996; 20: 675–705
   PubMed Web of Science ®Google Scholar
• Barnes S, Sfakianos J, Coward L, Kirk M. Soy isoflavanoids and cancer prevention: underlying biochemical and pharmacological issues. Adv Exp Med Biol 1996; 401: 87–100
   PubMedGoogle Scholar
• Anderson J W, Diwadkar V A, Bridges S R. Selective effects of different antioxidants on oxidation of lipoproteins from rats. Proc Soc Exp Biol Med 1998; 218: 376–381
   PubMed Web of Science ®Google Scholar
• Sanbongi C, Suzuki N, Sakane T. Polyphenols in chocolate, which have antioxidant activity, modulate immune functions in humans in vitro. Cellular Immunol 1997; 177: 129–136
   PubMed Web of Science ®Google Scholar
• Kumar A, Dhawan S, Hardegan N J, Aggarwal B B. Curcumin inhibition of TNF mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and NF-kB activation. Biochem Pharmacol 1998; 55: 775–783
   PubMed Web of Science ®Google Scholar
• Morrissey J J, Klahr S. Enalapril decreases nuclear factor kappa-B activation in the kidney with ureteral obstruction. Kidney Int 1997; 52: 926–933
   PubMed Web of Science ®Google Scholar
• Mak I T, Arroya C M, Weglieki W B. Inhibition of sarcolemmal carbon centred free radical formation by propanalol. Cire Res 1989; 65: 1151–1156
   PubMed Web of Science ®Google Scholar
• Cabell K S, La L, Johnson P. Effects of antihypertensive drugs on rat tissue antioxidant enzyme activities and lipid peroxidation levels. Biochem Pharmacol 1997; 54: 131–141
   Web of Science ®Google Scholar
• Tarif N, Bakris G L. Preservation of renal function: the spectrum of effects by calcium channel blockers. Nephrol Dial Transplant 1997; 12.: 244–2250
   Web of Science ®Google Scholar
• Feuerstein G Z, Ruffblo R R. Carvedilol, a novel multiple action antihypertensive agent with antioxidant activity and the potential for myocardial and vascular protection. Eur Hrt J 1995; 16: 38–42
   PubMed Web of Science ®Google Scholar
• FrishmaN W. Carvedilol. New Engl J Med 1998; 339: 1759–1765
   PubMed Web of Science ®Google Scholar
• van den Branden C, Gabriels M, Vamecq J, Van denHoute J, Verbcelen D. Carvedilol protects against glomerulosclerosis in rat remnant kidney without changes in antioxsidant status. Nephrom 1997; 77: 319–324
   PubMed Web of Science ®Google Scholar
• Molyneux L M, Willey K A, Yue D K. Iadapamide is as effective as captopril in the control of microalbu-minuria in diabetes. J Cardiovasc Pharmacol 1996; 27: 424–427
   PubMed Web of Science ®Google Scholar
• Uehara Y, Kawabata Y, Shirahase H, Wada K, Hashizume Y, Morishita S, Numabe A, Iwai J. Oxygen radical scavengers and renal protection by indapamide diuretic in salt induced hypertension of Dahl strain rats. J Cardiovasc Pharmacol 1993; 22(Suppl 6)S42–S46
   Google Scholar
• Numberg W, Cirahbe J, Czametski E. Synergistic effevts of pentoxifylline and dapsone in leucocytoclastic vasculitis. Lancet 1994; 343: 491
   Web of Science ®Google Scholar
• Castellot J J, Kamovsky M J, Wright T C. Effect of heparin on cellular proliferation Semin Thromb. Haemostas 1987; 13: 489–502
   Google Scholar
• Roccatello D, Mengozzi G, Ferro M, Cesano G. Isoscrbide 5 mononitrate increases nitric oxide blood levels and reduces proleinuna in IgA glomerulonephritis patients with abnormal urine endothelin e GMP ratio. Clin. Nephrology 1995; 44: 103–108
   Web of Science ®Google Scholar
• Trachtman H, Futterweit S, Singial P C. Nitric oxide moduiates synthesis of extracellular matrix proteins in cultured rat mesangial cells. Biochem Biophys Res Commun 1995; 207: 120–125
   PubMed Web of Science ®Google Scholar
• Prior R L, Cao G. Antioxidant capacity and polyphenolic componeuts of teas: implications for altering in vivo anlioxidant status. Proc Soc Exp Biol Med 1999; 220: 255–261
   PubMed Web of Science ®Google Scholar