959
Views
8
CrossRef citations to date
0
Altmetric
Laboratory Study

A deeper understanding of the association between CTLA4 +49A/G and acute rejection in renal transplantation: an updated meta-analysis

, , , &
Pages 165-174 | Received 27 Jun 2014, Accepted 03 Sep 2014, Published online: 09 Oct 2014

References

  • Alegre ML, Frauwirth KA, Thompson CB. T-cell regulation by CD28 and CTLA-4. Nat Rev Immunol. 2001;1(3):220–228
  • Grohmann U, Orabona C, Fallarino F, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol. 2002;3(11):1097–1101
  • Wing K, Onishi Y, Prieto-Martin P, et al. CTLA-4 control over Foxp3+ regulatory T cell function. Science. 2008;322(5899):271–275
  • Bouqbis L, Izaabel H, Akhayat O, et al. Association of the CTLA4 promoter region (−1661G allele) with type 1 diabetes in the South Moroccan population. Genes Immun. 2003;4(2):132–137
  • Hudson LL, Rocca K, Song YW, Pandey JP. CTLA-4 gene polymorphisms in systemic lupus erythematosus: A highly significant association with a determinant in the promoter region. Hum Genet. 2002;111(4–5):452–455
  • Ueda H, Howson JM, Esposito L, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature. 2003;423(6939):506–511
  • Gorgi Y, Sfar I, Abdallah TB, et al. Ctla-4 exon 1 (+49) and promoter (−318) gene polymorphisms in kidney transplantation. Transplant Proc. 2006;38(7):2303–2305
  • Wu J, Tang JL, Wu SJ, Lio HY, Yang YC. Functional polymorphism of CTLA-4 and ICOS genes in allogeneic hematopoietic stem cell transplantation. Clin Chim Acta. 2009;403(1–2):229–233
  • Kusztal M, Kościelska-Kasprzak K, Drulis-Fajdasz D, et al. The influence of CTLA-4 gene polymorphism on long-term kidney allograft function in Caucasian recipients. Transpl Immunol. 2010;23(3):121–124
  • Slavcheva E, Albanis E, Jiao Q, et al. Cytotoxic T-lymphocyte antigen 4 gene polymorphisms and susceptibility to acute allograft rejection. Transplantation. 2001;72(5):935–940
  • Tapirdamaz O, Pravica V, Metselaar HJ, et al. Polymorphisms in the T cell regulatory gene cytotoxic T lymphocyte antigen 4 influence the rate of acute rejection after liver transplantation. Gut. 2006;55(6):863–868
  • deReuver P, Pravica V, Hop W, et al. Recipient ctla-4 +49G/G genotype is associated with reduced incidence of acute rejection after liver transplantation. Am J Transplant. 2003;3(12):1587–1594
  • Duan Z, Zhang Y, Pan F, et al. Association between CTLA4 gene polymorphisms and acute rejection of kidney transplantation: A meta-analysis. J Nephrol. 2012;25(6):996–1002
  • Zhu CL, Huang Q, Liu CH, Xie F. Polymorphisms in the cytotoxic T-lymphocyte antigen 4 gene and acute rejection risk in transplant recipients. Mol Biol Rep. 2012;39(9):8701–8708
  • Dmitrienko S, Hoar DI, Balshaw R, Keown PA. Immune response gene polymorphisms in renal transplant recipients. Transplantation. 2005;80(12):1773–1782
  • Wisniewski A, Kusztal M, Magott-Procelewska M, et al. Possible association of cytotoxic T-lymphocyte antigen 4 gene promoter single nucleotide polymorphism with acute rejection of allogeneic kidney transplant. Transpl Proc. 2006;38(1):56–58
  • Gendzekhadze K, Rivas-Vetencourt P, Montano RF. Risk of adverse post-transplant events after kidney allograft transplantation as predicted by CTLA-4 +49 and TNF-a-308 single nucleotide polymorphisms: A preliminary study. Transpl Immunol. 2006;16(3–4):194–199
  • Haimila K, Turpeinen H, Alakulppi NS, Kyllönen LE, Salmela KT, Partanen J. Association of genetic variation in inducible costimulator gene with outcome of kidney transplantation. Transplantation. 2009;87(3):393–396
  • Ruhi C, Sallakci N, Ersoy F, Yegin O, Süleymanlar G. The relation between CTLA-4 single nucleotide polymorphisms and acute rejection in kidney transplantation. NDT Plus. 2010;Suppl 3:iii524–iii525
  • Domański L, Bobrek-Lesiakowska K, Kłoda K, et al. The impact of rs231775 (+49AG) CTLA4 gene polymorphism on transplanted kidney function. Ann Transplant. 2012;17(3):29–35
  • Kim HJ, Jeong KH, Lee SH, et al. Polymorphisms of the CTLA4 gene and kidney transplant rejection in Korean patients. Transpl Immunol. 2010;24(1):40–44
  • Gao JW, Guo YF, Fan Y, et al. Polymorphisms in cytotoxic T lymphocyte associated antigen-4 influence the rate of acute rejection after renal transplantation in 167 Chinese recipients. Transpl Immunol. 2012;26(4):207–211
  • Zhao SX, Pan CM, Cao HM, et al. Association of the CTLA4 gene with Graves’ disease in the Chinese Han population. PLoS One. 2010;5(3):e9821
  • Chang WW, Zhang L, Yao YS, Su H. Association between CTLA-4 exon-1 +49A/G polymorphism and systemic lupus erythematosus: An updated analysis. Mol Biol Rep. 2012;39(9):9159–9165
  • Cho CS, Kim HY, Pyo CW, et al. The distribution of CTLA-4 alleles in Korean patients with SLE. Korean J Immunol. 2000;22:17–22
  • Lee YH, Kim YR, Ji JD, Sohn J, Song GG. Polymorphisms of the CTLA-4 exon 1 and promoter gene in systemic lupus erythematosus. Lupus. 2001;10(9):601–605
  • Ahmed S, Ihara K, Kanemitsu S, Nakashima H, Otsuka T. Association of CTLA-4 but not CD28 gene polymorphisms with systemic lupus erythematosus in the Japanese population. Rheumatology (Oxford). 2001;40(6):662–667
  • Matsushita M, Tsuchiya N, Shiota M, et al. Lack of a strong association of CTLA-4 exon 1 polymorphism with the susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese: An association study using a novel variation screening method. Tissue Antigens. 1999;54(6):578–584
  • Takeuchi F, Kawasugi K, Nabeta H, Mori M, Tanimoto K. CTLA-4 dimorphisms in Japanese patients with systemic lupus erythematosus. Clin Exp Rheumatol. 2003;21(4):527–528
  • Aguilar F, Torres B, Sánchez-Román J, Núñez-Roldán A, González-Escribano MF. CTLA-4 polymorphism in Spanish patients with systemic lupus erythematosus. Hum Immunol. 2003;64(10):936–940
  • Barreto M, Santos E, Ferreira R, et al. Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus. Eur J Hum Genet. 2004;12(8):620–626
  • Heward J, Gordon C, Allahabadia A, Barnett AH, Franklyn JA, Gough SC. The A-G polymorphism in exon 1 of the CTLA-4 gene is not associated with systemic lupus erythematosus. Ann Rheum Dis. 1999;58(3):193–195
  • Brozzetti A, Marzotti S, Tortoioli C, et al. Cytotoxic T lymphocyte antigen-4 Ala17 polymorphism is a genetic marker of autoimmune adrenal insufficiency: Italian association study and meta-analysis of European studies. Eur J Endocrinol. 2010;162(2):361–369
  • Ligers A, Teleshova N, Masterman T, Huang W, Hillert J. CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms. Genes Immun. 2001;2(3):145–152
  • Sun T, Zhou Y, Yang M, et al. Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer. Cancer Res. 2008;68(3):7025–7034
  • Nistico L, Buzzetti R, Pritchard LE, et al. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Hum Mol Genet. 1996;5:1075–1080
  • Kavvoura FK, Akamizu T, Awata T, et al. Cytotoxic T-lymphocyte associatedantigen 4 gene polymorphisms and autoimmune thyroid disease: A meta-analysis. J Clin Endocrinol Metab. 2007;92(7):3162–3170
  • Munoz-Valle JF, Valle Y, Padilla-Gutierrez JR, et al. The +49A>G CTLA-4 polymorphism is associated with rheumatoid arthritis in Mexican population. Clin Chim Acta. 2010;411(9–10):725–728
  • Miyake Y, Ikeda F, Takaki A, Nouso K, Yamamoto K. +49A/G polymorphism of cytotoxic T-lymphocyte antigen 4 gene in type 1 autoimmune hepatitis and primary biliary cirrhosis: A meta-analysis. Hepatol Res. 2011;41(2):151–159
  • Thornton A, Lee P. Publication bias in meta-analysis: Its causes and consequences. J Clin Epidemiol. 2000;53(2):207–221

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.