1,218
Views
22
CrossRef citations to date
0
Altmetric
Laboratory Study

Renoprotective effect of aliskiren on renal ischemia/reperfusion injury in rats: electron microscopy and molecular study

, , , , , , , , , & show all
Pages 343-354 | Received 27 Aug 2014, Accepted 18 Nov 2014, Published online: 19 Dec 2014

References

  • Zimmerman BJ, Granger DN. Reperfusion injury. Surg Clin North America. 1992;72(1):65–83
  • Huang WC, Elkin EB, Levey AS, Jang TL, Russo P. Partial nephrectomy versus radical nephrectomy in patients with small renal tumors – is there a difference in mortality and cardiovascular outcomes? J Urol. 2009;181(1):55–61; discussion 61–62
  • Janetschek G. Laparoscopic partial nephrectomy for RCC: How can we avoid ischemic damage of the renal parenchyma? Eur Urol. 2007;52(5):1303–1305
  • Gao Y, Chen L, Ning Y, et al. Hydro-Jet-assisted laparoscopic partial nephrectomy with no renal arterial clamping: A preliminary study in a single center. Int Urol Nephrol. 2014;46(7):1289–1293
  • Versteilen AM, Di Maggio F, Leemreis JR, Groeneveld AB, Musters RJ, Sipkema P. Molecular mechanisms of acute renal failure following ischemia/reperfusion. Int J Artif Organs. 2004;27(12):1019–1029
  • Molitoris BA, Sutton TA. Endothelial injury and dysfunction: Role in the extension phase of acute renal failure. Kidney Int. 2004;66(2):496–499
  • Edelstein CL, Ling H, Wangsiripaisan A, Schrier RW. Emerging therapies for acute renal failure. Am J Kidney Dis. 1997;30(5 Suppl 4):S89–S95
  • Mackie FE, Campbell DJ, Meyer TW. Intrarenal angiotensin and bradykinin peptide levels in the remnant kidney model of renal insufficiency. Kidney Int. 2001;59(4):1458–1465
  • Siamopoulos KC, Kalaitzidis RG. Inhibition of the renin-angiotensin system and chronic kidney disease. Int Urol Nephrol. 2008;40(4):1015–1025
  • Koid SS, Ziogas J, Campbell DJ. Aliskiren reduces myocardial ischemia–reperfusion injury by a bradykinin B2 receptor- and angiotensin AT2 receptor-mediated mechanism. Hypertension. 2014;63(4):768–773
  • Zhang W, Han Y, Meng G, et al. Direct renin inhibition with aliskiren protects against myocardial ischemia/reperfusion injury by activating nitric oxide synthase signaling in spontaneously hypertensive rats. J Am Heart Assoc. 2014;3(1):e000606
  • Choi DE, Jeong JY, Lim BJ, et al. Aliskiren ameliorates renal inflammation and fibrosis induced by unilateral ureteral obstruction in mice. J Urol. 2011;186(2):694–701
  • Moriyama T, Tsuruta Y, Kojima C, et al. Beneficial effect of aliskiren combined with olmesartan in reducing urinary protein excretion in patients with chronic kidney disease. Int Urol Nephrol. 2012;44(3):841–845
  • Lizakowski S, Tylicki L, Renke M, et al. Effect of aliskiren on proteinuria in non-diabetic chronic kidney disease: A double-blind, crossover, randomised, controlled trial. Int Urol Nephrol. 2012;44(6):1763–1770
  • Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem. 1988;34(3):497–500
  • Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman’s reagent. Anal Biochem. 1968;25(1):192–205
  • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95(2):351–358
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25(4):402–408
  • Schrier RW, Wang W. Acute renal failure and sepsis. N Engl J Med. 2004;351(2):159–169
  • Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Curr Opin Nephrol Hypertens. 2007;16(6):557–564
  • Grace PA. Ischemia–reperfusion injury. Br J Surg. 1994;81(5):637–647
  • Anaya-Prado R, Toledo-Pereyra LH, Lentsch AB, Ward PA. Ischemia/reperfusion injury. J Surg Res. 2002;105(2):248–258
  • Masztalerz M, Wlodarczyk Z, Czuczejko J, Slupski M, Kedziora J. Superoxide anion as a marker of ischemia–reperfusion injury of the transplanted kidney. Transplant Proc. 2006;38(1):46–48
  • Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys. 1991;288(2):481–487
  • Szabo C, Zingarelli B, O’Connor M, Salzman AL. DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc Nat Acad Sci USA. 1996;93(5):1753–1758
  • MacMillan-Crow LA, Crow JP, Kerby JD, Beckman JS, Thompson JA. Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts. Proc Nat Acad Sci USA. 1996;93(21):11853–11858
  • Yamakura F, Taka H, Fujimura T, Murayama K. Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine. J Biol Chem. 1998;273(23):14085–14089
  • Singh I, Gulati S, Orak JK, Singh AK. Expression of antioxidant enzymes in rat kidney during ischemia-reperfusion injury. Mol Cell Biochem. 1993;125(2):97–104
  • Davies SJ, Reichardt-Pascal SY, Vaughan D, Russell GI. Differential effect of ischemia–reperfusion injury on anti-oxidant enzyme activity in the rat kidney. Exp Nephrol. 1995;3(6):348–354
  • Conti M, Eschwege P, Ahmed M, et al. Antioxidant enzymatic activities and renal warm ischemia: Correlation with the duration of ischemia. Transplant Proc. 2000;32(8):2740–2741
  • Kontogiannis J, Burns KD. Role of AT1 angiotensin II receptors in renal ischemic injury. Am J Physiol. 1998;274(1 Pt 2):F79–F90
  • Hammad FT, Wheatley AM, Davis G. Long-term renal effects of unilateral ureteral obstruction and the role of endothelin. Kidney Int. 2000;58(1):242–250
  • Habibey R, Ajami M, Hesami A, Pazoki-Toroudi H. The mechanism of preventive effect of captopril on renal ischemia reperfusion injury is independent of ATP dependent potassium channels. Iran Biomed J. 2008;12(4):241–245
  • Molinas SM, Cortes-Gonzalez C, Gonzalez-Bobadilla Y, et al. Effects of losartan pretreatment in an experimental model of ischemic acute kidney injury. Nephron Exp Nephrol. 2009;112(1):e10–e19
  • Hammad FT, Al-Salam S, Lubbad L. Does aliskiren protect the kidney following ischemia reperfusion injury? Physiol Res. 2013;62(6):681–690
  • Schmerbach K, Pfab T, Zhao Y, et al. Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes. PLoS One. 2010;5(11):e15052
  • Shi X, Yan C, Nadtochiy SM, Abe J, Brookes PS, Berk BC. p90 Ribosomal S6 kinase regulates activity of the renin-angiotensin system: A pathogenic mechanism for ischemia–reperfusion injury. J Mol Cell Cardiol. 2011;51(2):272–275
  • Oyamada S, Bianchi C, Takai S, et al. Impact of acute myocardial ischemia reperfusion on the tissue and blood-borne renin–angiotensin system. Basic Res Cardiol. 2010;105(4):513–522
  • Kim SM, Kim YG, Jeong KH, et al. Angiotensin II-induced mitochondrial Nox4 is a major endogenous source of oxidative stress in kidney tubular cells. PLoS One. 2012;7(7):e39739
  • Thurman JM. Triggers of inflammation after renal ischemia/reperfusion. Clin Immunol. 2007;123(1):7–13
  • Rashikh A, Ahmad SJ, Pillai KK, Kohli K, Najmi AK. Aliskiren attenuates myocardial apoptosis and oxidative stress in chronic murine model of cardiomyopathy. Biomed Pharmacother. 2012;66(2):138–143
  • Kacmaz A, Polat A, User Y, Tilki M, Ozkan S, Sener G. Octreotide improves reperfusion-induced oxidative injury in acute abdominal hypertension in rats. J Gastrointest Surg. 2004;8(1):113–119
  • Li N, Wu X, Li L. Chronic administration of clozapine alleviates reversal-learning impairment in isolation-reared rats. Behav Pharmacol. 2007;18(2):135–145
  • Ikeda U, Maeda Y, Kawahara Y, Yokoyama M, Shimada K. Angiotensin II augments cytokine-stimulated nitric oxide synthesis in rat cardiac myocytes. Circulation. 1995;92(9):2683–2689
  • Haidara MA, Yassin HZ, Rateb M, Ammar H, Zorkani MA. Role of oxidative stress in development of cardiovascular complications in diabetes mellitus. Curr Vascul Pharmacol. 2006;4(3):215–227
  • Adachi Y, Hashimoto K, Ono N, et al. Renal effects of a nitric oxide donor, NOC 7, in anesthetized rabbits. Eur J Pharmacol. 1997;324(2–3):223–226
  • Kim JI, Jang HS, Park KM. Endotoxin-induced renal tolerance against ischemia and reperfusion injury is removed by iNOS, but not eNOS, gene-deletion. BMB Rep. 2010;43(9):629–634
  • Modlinger PS, Wilcox CS, Aslam S. Nitric oxide, oxidative stress, and progression of chronic renal failure. Semin Nephrol. 2004;24(4):354–365
  • Walker LM, Walker PD, Imam SZ, Ali SF, Mayeux PR. Evidence for peroxynitrite formation in renal ischemia-reperfusion injury: Studies with the inducible nitric oxide synthase inhibitor L-N(6)-(1-Iminoethyl)lysine. J Pharmacol Exp Ther. 2000;295(1):417–422
  • Chatterjee PK, Patel NS, Sivarajah A, et al. GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Kidney Int. 2003;63(3):853–865
  • Mark LA, Robinson AV, Schulak JA. Inhibition of nitric oxide synthase reduces renal ischemia/reperfusion injury. J Surg Res. 2005;129(2):236–241
  • Tan CK, Tan EH, Luo B, et al. SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS. J Am Heart Assoc. 2013;2(3):e000269
  • Hayashi T, Takai S, Yamashita C. Impact of the renin–angiotensin-aldosterone-system on cardiovascular and renal complications in diabetes mellitus. Curr Vascul Pharmacol. 2010;8(2):189–197
  • Camara-Lemarroy CR, Guzman-de la Garza FJ, Alarcon-Galvan G, Cordero-Perez P, Fernandez-Garza NE. Effect of sulfasalazine on renal ischemia/reperfusion injury in rats. Renal Fail. 2009;31(9):822–828
  • Liu WJ, Tang HT, Jia YT, et al. Notoginsenoside R1 attenuates renal ischemia–reperfusion injury in rats. Shock. 2010;34(3):314–320
  • Ilieva I, Ohgami K, Jin XH, et al. Captopril suppresses inflammation in endotoxin-induced uveitis in rats. Exp Eye Res. 2006;83(3):651–657
  • He X, Han B, Mura M, et al. Angiotensin-converting enzyme inhibitor captopril prevents oleic acid-induced severe acute lung injury in rats. Shock. 2007;28(1):106–111
  • Casas JP, Chua W, Loukogeorgakis S, et al. Effect of inhibitors of the renin–angiotensin system and other antihypertensive drugs on renal outcomes: Systematic review and meta-analysis. Lancet. 2005;366(9502):2026–2033
  • MacKinnon M, Shurraw S, Akbari A, Knoll GA, Jaffey J, Clark HD. Combination therapy with an angiotensin receptor blocker and an ACE inhibitor in proteinuric renal disease: A systematic review of the efficacy and safety data. Am J Kidney Dis. 2006;48(1):8–20
  • Berthonneche C, Sulpice T, Tanguy S, et al. AT1 receptor blockade prevents cardiac dysfunction after myocardial infarction in rats. Cardiovas Drugs Ther. 2005;19(4):251–259
  • Wu B, Lin R, Dai R, Chen C, Wu H, Hong M. Valsartan attenuates oxidative stress and NF-kappaB activation and reduces myocardial apoptosis after ischemia and reperfusion. Eur J Pharmacol. 2013;705(1–3):140–147
  • Friedewald JJ, Rabb H. Inflammatory cells in ischemic acute renal failure. Kidney Int. 2004;66(2):486–491
  • Farrar CA, Wang Y, Sacks SH, Zhou W. Independent pathways of P-selectin and complement-mediated renal ischemia/reperfusion injury. Am J Pathol. 2004;164(1):133–141
  • Singbartl K, Ley K. Leukocyte recruitment and acute renal failure. J Mol Med. 2004;82(2):91–101
  • Singh V, Jain S, Gowthaman U, et al. Co-administration of IL-1 + IL-6 + TNF-alpha with Mycobacterium tuberculosis infected macrophages vaccine induces better protective T cell memory than BCG. PLoS One. 2011;6(1):e16097
  • Schreiber S, Nikolaus S, Hampe J, et al. Tumour necrosis factor alpha and interleukin 1beta in relapse of Crohn’s disease. Lancet. 1999;353(9151):459–461

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.