76
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Effect of 14-kDa and 47-kDa protein molecules of age garlic extract on peritoneal macrophages

, , , , &
Pages 21-27 | Received 25 Dec 2009, Accepted 09 Feb 2010, Published online: 23 Mar 2010

References

  • Iciek, M., Kwiecien, I., Wlodek, L. Biological properties of garlic and garlic-derived organosulfur compounds. Environ. Mol. Mutagen. 2009, 50, 247–265.
  • Yoshida, H., Iwata, N., Katsuzaki, H., Naganawa, R., Ishikawa, K., Fukuda, H., Fujino, T., Suzuki, A. Antimicrobial activity of a compound isolated from an oil-macerated garlic extract. Biosci. Biotechnol. Biochem. 1998, 62, 1014–1017.
  • Karasaki, Y., Tsukamoto, S., Mizusaki, K., Sugiura, T., Gotoh, S. A garlic lectin exerted an antitumor activity and induced apoptosis in human tumor cells. Food. Res. Int. 2001;34:7–13.
  • Durak, I., Oztürk, H.S., Olcay, E., Güven, C. Effects of garlic extract supplementation on blood lipid and antioxidant parameters and atherosclerotic plaque formation process in cholesterol-fed rabbits. J. Herb. Pharmacother. 2002, 2, 19–32.
  • Kumar, V.G., Surendranathan, K.P., Umesh, K.G., Gayathri Devi, D.R., Belwadi, M.R. Effect of onion (Allium cepa Linn.) and garlic (Allium sativum Linn.) on plasma triglyceride content in Japanese quail (Coturnix coturnix japonicum). Indian J. Exp. Biol. 2003, 41, 88–90.
  • Matsuura, N., Miyamae, Y., Yamane, K., Nagao, Y., Hamada, Y., Kawaguchi, N., Katsuki, T., Hirata, K., Sumi, S., Ishikawa, H. Aged garlic extract inhibits angiogenesis and proliferation of colorectal carcinoma cells. J. Nutr. 2006, 136, 842S–846S.
  • Ide, N., Keller, C., Weiss, N. Aged garlic extract inhibits homocysteine-induced CD36 expression and foam cell formation in human macrophages. J. Nutr. 2006, 136, 755S–758S.
  • Wei, Z., Lau, B.H. Garlic inhibits free radical generation and augments antioxidant enzyme activity in vascular endothelial cells. Nutr. Res. 1998;18:61–70.
  • Yaraei R, Saraf-Nejad A, Nozari B, Ghazanfari T, Hassan ZM. The effect of garlic extract and its fractions on natural killer activity. India: Abstract Book of 10th International Congress of Immunology, 1998: 493.
  • Ghazanfari, T., Hassan, Z.M., Ebrahimi, M. Immunomodulatory activity of a protein isolated from garlic extract on delayed type hypersensitivity. Int. Immunopharmacol. 2002, 2, 1541–1549.
  • Nikoo, S., Bozorgmehr, M., Namdar Ahmadabad, H., Hassan, Z.M., Moazzeni, S.M., Pourpak, Z., Ghazanfari, T. The 14kDa protein molecule isolated from garlic suppresses indoleamine 2, 3-dioxygenase metabolites in mononuclear cells in vitro. Iran. J. Allergy. Asthma. Immunol. 2008, 7, 203–208.
  • Chang, H.P., Huang, S.Y., Chen, Y.H. Modulation of cytokine secretion by garlic oil derivatives is associated with suppressed nitric oxide production in stimulated macrophages. J. Agric. Food Chem. 2005, 53, 2530–2534.
  • Cho, S.J., Rhee, D.K., Pyo, S. Allicin, a major component of garlic, inhibits apoptosis of macrophage in a depleted nutritional state. Nutrition 2006, 22, 1177–1184.
  • Stuehr, D.J., Nathan, C.F. Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J. Exp. Med. 1989, 169, 1543–1555.
  • Scuro, L.S., Simioni, P.U., Grabriel, D.L., Saviani, E.E., Modolo, L.V., Tamashiro, W.M., Salgado, I. Suppression of nitric oxide production in mouse macrophages by soybean flavonoids accumulated in response to nitroprusside and fungal elicitation. BMC Biochem. 2004, 5, 5.
  • Sladowski, D., Steer, S.J., Clothier, R.H., Balls, M. An improved MTT assay. J. Immunol. Methods 1993, 157, 203–207.
  • Hansen, M.B., Nielsen, S.E., Berg, K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immunol. Methods 1989, 119, 203–210.
  • Eskandari, M.K., Nguyen, D.T., Kunkel, S.L., Remick, D.G. WEHI 164 subclone 13 assay for TNF: sensitivity, specificity, and reliability. Immunol. Invest. 1990, 19, 69–79.
  • Butt, M.S., Sultan, M.T., Butt, M.S., Iqbal, J. Garlic: nature’s protection against physiological threats. Crit. Rev. Food Sci. Nutr. 2009, 49, 538–551.
  • Agarwal, K.C. Therapeutic actions of garlic constituents. Med. Res. Rev. 1996, 16, 111–124.
  • Chandrashekar, P.M., Venkatesh, Y.P. Identification of the protein components displaying immunomodulatory activity in aged garlic extract. J. Ethnopharmacol. 2009, 124, 384–390.
  • Wen, G.Y., Mato, A., Wisniewski, H.M., Malik, M.N., Jenkins, E.C., Sheikh, A.M., Kim, K.S. Light and electron microscopic immunocytochemical localization of two major proteins in garlic bulb. J. Cell. Biochem. 1995, 58, 481–489.
  • Ghazanfari T, Hassan ZM. A lectine with mitogenic activity in garlic. India: Abstract Book of 10th International Congress of Immunology, 1998: 493.
  • Zare, A., Farzaneh, P., Pourpak, Z., Zahedi, F., Moin, M., Shahabi, S., Hassan, Z.M. Purified aged garlic extract modulates allergic airway inflammation in BALB/c mice. Iran. J. Allergy. Asthma. Immunol. 2008, 7, 133–141.
  • Borek, C. Antioxidant health effects of aged garlic extract. J. Nutr. 2001, 131, 1010S–1015S.
  • Dirsch, V.M., Kiemer, A.K., Wagner, H., Vollmar, A.M. Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase. Atherosclerosis 1998, 139, 333–339.
  • Bruck, R., Aeed, H., Brazovsky, E., Noor, T., Hershkoviz, R. Allicin, the active component of garlic, prevents immune-mediated, concanavalin A-induced hepatic injury in mice. Liver Int. 2005, 25, 613–621.
  • Karmakar, S., Banik, N.L., Patel, S.J., Ray, S.K. Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells. Apoptosis 2007, 12, 671–684.
  • Das, I., Khan, N.S., Sooranna, S.R. Potent activation of nitric oxide synthase by garlic: a basis for its therapeutic applications. Curr. Med. Res. Opin. 1995, 13, 257–263.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.