Pharmacokinetics of radiolabeled tungsten (¹⁸⁸W) in male Sprague-Dawley rats following acute sodium tungstate inhalation

References

• Aamodt, R. L. (1975). Inhalation of 181W labeled tungstic oxide by six beagle dogs. Health Phys 28, 733–743.
   PubMedGoogle Scholar
• Ammerman, C., Fontenot, J., Spivey-Fox, M., Hutchinson, H., Lepore, P., Stowe, H., Thompson, D., and Ullrey, D. (1980). Mineral Tolerance of Domestic Animals. National Academy Press, Washington, DC, pp. 515–523.
   Google Scholar
• Boxenbaum, H. G., Riegelman, S., and Elashoff, R. M. (1974). Statistical estimations in pharmacokinetics. J Pharmacokinet Biopharm 2, 123–148.
   PubMedGoogle Scholar
• Centers for Disease Control and Protection. (2003). Cross-sectional exposure assessment of environmental contaminants in Churchill County, Nevada. Final report. Atlanta, GA, Centers for Disease Control and Prevention. http://www.cdc.gov/nceh/clusters/Fallon/study.htm.
   Google Scholar
• Cherry, D. M., and Amy, N. K. (1987). Effect of dietary protein and iron on the fractional turnover rate of rat liver xanthine oxidase. 117, 2054–2060.
   Google Scholar
• Fernandez-Alvarez, J., Barbera, A., Nadal, B., Barcelo-Batllori, S., Piquer, S., Claret, M.,Guinovart, J. J., and Gomis, R. (2004). Stable and functional regeneration of pancreatic beta-cell population in nSTZ-rats treated with tungstate. Diabetologia 47, 470–477.
   PubMed Web of Science ®Google Scholar
• Gibaldi, M., and Perrier, D. (1982). Pharmacokinetics. Marcel Dekker, New York.
   Google Scholar
• Gold, K., Cheng, Y. S., and Holmes, T. D. (2007). A quantitative analysis of aerosols inside an armored vehicle perforated by a kinetic energy penetrator containing tungsten, nickel, and cobalt. Mil Med 172, 393–398.
   PubMedGoogle Scholar
• Haneke, K. E. (2003). Toxicological summary for tungsten and selected tungsten compounds. http://ntp.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/tungsten.pdf.
   Google Scholar
• Hinds, W. C. (1999). Aerosol Technology, 2nd edition. John Wiley and Sons, New York.
   Google Scholar
• Johnson, J. L., Waud, W. R., Cohen, H. J., and Rajagopalan, K. V. (1974). Molecular basis of the biological function of molybdenum: Molybdenum-free xanthine oxidase from livers of tungsten-treated rats. J Biol Chem 249, 5056–5061.
   PubMedGoogle Scholar
• Kalinich, J. F., Emond, C. A., Dalton, T. K., Mog, S. R., Coleman, G. D., Kordell, J.E., Miller, A. C., and McClain, D. E. (2005). Embedded weapons-grade tungsten alloy shrapnel rapidly induces metastatic high-grade rhabdomyosarcomas in F344 rats. Environ Health Perspect 113, 729–734.
   PubMed Web of Science ®Google Scholar
• Keith, L. S., Moffett, D. B., Rosemond, Z. A. and Wohlers, D.W. (2007). ATSDR evaluation of health effects of tungsten and relevance to public health. Toxicol Ind Health 23, 347–387.
   PubMed Web of Science ®Google Scholar
• Koutsospyros, A., Braida, W., Christodoulatos, C., Dermatas, D., and Strigul, N. (2006). A review of tungsten: From environmental obscurity to scrutiny. J Hazard Mater 136, 1–19.
   PubMed Web of Science ®Google Scholar
• Kraus, T., Schramel, P., Schaller, K. H., Zöbelein, P., Weber, A., and Angerer, J. (2001). Exposure assessment in the hard metal manufacturing industry with special regard to tungsten and its compounds. Occup Environ Med. 58, 631–634.
   PubMed Web of Science ®Google Scholar
• Lagarde, F., and Leroy, M. (2002). Metabolism and toxicity of tungsten in humans and animals. Met Ions Biol Systems 39, 741–759.
   PubMedGoogle Scholar
• Le Lamer, S., Cros, G., Pinol, C., Fernandez-Alvarez, J.,,and Bressolle, F. (2002). An application of population kinetics analysis to estimate pharmacokinetic parameters of sodium tungstate after multiple-dose during preclinical studies in rats. Pharmacol Toxicol 90, 100–105.
   PubMedGoogle Scholar
• Le Lamer, S., Cros, G., Serrano, J. J., Pinol, C., Fernandez-Alvarez, J., and Bressolle, F. (2001). Estimation of pharmacokinetic parameters of sodium tungstate after multiple-dose during preclinical studies in beagle dogs. Eur J Pharm Sci 14, 323–329.
   PubMedGoogle Scholar
• Leggett, R. W. (1997). A model of the distribution and retention of tungsten in the human body. Sci Total Environ 206, 147–165.
   PubMed Web of Science ®Google Scholar
• Linksvan der Voet, G. B., Todorov, T. I., Centeno, J. A., Jonas, W., Ives, J., and Mullick, F. G. (2007). Metals and health: A clinical toxicological perspective on tungsten and review of the literature. Mil Med 172, 1002–1005.
   PubMedGoogle Scholar
• McDonald, J. D., Weber, W. M., Marr, R., Kracko, D., Khain, H., and Arimoto, R. (2007). Disposition and clearance of tungsten after single-dose oral and intravenous exposure in rodents. J Toxicol Environ Health A 70, 829–836.
   PubMed Web of Science ®Google Scholar
• Menzies, R. A., and Gold, P. H. (1971). The turnover of mitochondria in a variety of tissues of young, adult and aged rats. J Biol Chem 246, 2425–2429.
   PubMed Web of Science ®Google Scholar
• Miller, A. C., Mog, S., McKinney, L., Luo, L., Allen, J., Xu, J., and Page, N. (2001). Neoplastic transformation of human osteoblast cells to the tumorigenic phenotype by heavy metal–tungsten alloy particles: Induction of genotoxic effects. Carcinogenesis 22, 115–125.
   PubMedGoogle Scholar
• Mitchell, R. R., Fitzgerald, S. D., Aulerich, R. J., Balander, R. J., Powell, D.C., Tempelman, R. J., Cray, C., Stevens, W., and Bursian, S. J. (2001). Hematological effects and metal residue concentrations following chronic dosing with tungsten–iron and tungsten-polymer shot in adult game-farm mallards. J Wildl Dis 37, 459–467.
   PubMedGoogle Scholar
• Muñoz, M. C., Barberà, A., Domínguez, J., Fernàndez-Alvarez, J., Gomis, R., and Guinovart, J. J. (2001). Effects of tungstate, a new potential oral antidiabetic agent, in Zucker diabetic fatty rats. Diabetes 50, 131–138.
   PubMed Web of Science ®Google Scholar
• National Research Council. (1996). Guide for the Care and Use of Laboratory Animals. National Academy Press, Washington, DC.
   Google Scholar
• National Toxicology Program. (2003). Toxicological summary for tungsten and selected tungsten compounds. Review of toxicological literature. ntp.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/tungsten.pdf.
   Google Scholar
• Nicolaou, G., Pietra, R., Sabbioni, E., Mosconi, G., Cassina, G., and Seghizzi, P. (1987). Multielement determination of metals in biological specimens of hard metal workers: A study carried out by neutron activation analysis. J Trace Elem Electrolytes Health Dis. 1, 73–77.
   PubMedGoogle Scholar
• Radcliffe, P. M., Olabisi, A. O., Wagner, D. J., Leavens, T. L., Wong, B. A., Struve, M. F., Chapman, G. D., Wilfong, E. R., and Dorman, D. C. (2009). Acute sodium tungstate inhalation is associated with minimal olfactory transport of tungsten (188W) to the rat brain. Neurotoxicology (in press).
   Google Scholar
• Rubin, C. S., Holmes, A. K., Belson, M. G., Jones, R. L., Flanders, W. D., Kieszak, S. M., Osterloh, J., Luber, G. E., Blount, B. C., Barr, D. B., Steinberg, K. K., Satten, G. A., McGeehin, M. A., and Todd, R. L. (2007). Investigating childhood leukemia in Churchill County, Nevada. Environ Health Perspect 115, 151–157.
   PubMed Web of Science ®Google Scholar
• Schell, J., and Pardus, M. (2008). Tungsten and cobalt in Fallon, Nevada: association with childhood leukemia. Environ Health Perspect 116, A196–197.
   PubMedGoogle Scholar
• Sheppard, P. R., Speakman, R. J., Ridenour, G., and Witten, M. L. (2007). Temporal variability of tungsten and cobalt in Fallon, Nevada. Environ Health Perspect 115, 715–719.
   PubMed Web of Science ®Google Scholar
• Strigul, N., Koutsospyros, A., Arienti, P., Christodoulatos, C., Dermatas, D., and Braida, W. (2005). Effects of tungsten on environmental systems. Chemosphere 61, 248–258.
   Google Scholar
• Vouk V. H., and Piver, W. T. (1983). Metallic elements in fossil fuel combustion products: amounts and form of emissions and evaluation of carcnogenicity and mutagenicity. Envriron. Health Perspect. 47, 201–225.
   PubMed Web of Science ®Google Scholar
• Wide, M., Danielsson, B. R., and Dencker, L. (1986). Distribution of tungstate in pregnant mice and effects on embryonic cells in vitro. Environ Res 40, 487–498.
   PubMedGoogle Scholar