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Inhalation Toxicology
International Forum for Respiratory Research
Volume 26, 2014 - Issue 11
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Research Article

The National Environmental Respiratory Center (NERC) experiment in multi-pollutant air quality health research: III. Components of diesel and gasoline engine exhausts, hardwood smoke and simulated downwind coal emissions driving non-cancer biological responses in rodents

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Pages 668-690 | Received 08 Apr 2014, Accepted 25 Apr 2014, Published online: 27 Aug 2014

References

  • Barrasa M, Lamosa S, Fernandez MD, Fernandez E. (2012). Occupational exposure to carbon dioxide, ammonia, and hydrogen sulphide on livestock farms in northwest Spain. Ann Agri Environ Med 19:17–24
  • Barrett EG, Day KC, Gigliotti AP, et al. (2011). Effects of simulated downwind coal combustion emissions on pre-existing allergic airway responses in mice. Inhal Toxicol 23:792–804
  • Brightwell J, Fouillet X, Cassano-Zoppi AL, et al. (1986). Neoplastic and functional changes in rodents after chronic inhalation of engine exhaust emissions. In: Ishinishi N, Koizumi A, McClellan RO, Stöber W, (eds.) Carcinogenic and mutagenic effects of diesel engine exhaust. New York: Elsevier, 471–85
  • Campen MJ, McDonald JD, Gigliotti AP, et al. (2003). Cardiovascular effects of inhaled diesel exhaust in spontaneously hypertensive rats. Cardiovasc Toxicol 3:353–61
  • Coull BA, Wellenius GA, Gonzales-Flecha B, et al. (2011). The toxicological evaluation of realistic emission source aerosols study: statistical methods. Inhal Toxicol 23:31–41
  • Fedoruk MJ, Brownstein R, Kerger BD. (2005). Ammonia exposure and hazard assessment for selected household cleaning product uses. J Expo Anal Environ Epidemiol 15:534–44
  • Friedman JH, Meulman JJ. (2003). Multiple additive regression trees with application in epidemiology. Stat Med 22:1365–81
  • Friedman JH. (2001). Greedy function approximation: a gradient boosting machine. Ann Stat 29:1189–232
  • Friedman JH. (2002). Stochastic gradient boosting. Comput Stat Data Anal 38:367–78
  • Godleski JJ, Diaz EA, Lemos M, et al. (2011c). Toxicological evaluation of realistic emission source aerosols (TERESA): assessment of cellular responses. Inhal Toxicol 23:60–74
  • Godleski JJ, Rohr AC, Coull BA, et al. (2011b). Toxicological evaluation of realistic emission source aerosols (TERESA): summary and conclusions. Inhal Toxicol 23:95–103
  • Godleski JJ, Rohr AC, Kang CM, et al. (2011a). Toxicological evaluation of realistic emission source aerosols (TERESA): introduction and overview. Inhal Toxicol 23:1–10
  • Hastie T, Tibrishani R, Friedman J. (2001). The elements of statistical learning; data mining, inference, and prediction. New York: Springer
  • Holness DL, Purdham JT, Nethercott JR. (1989). Acute and chronic respiratory effects of occupational exposure to ammonia. Am Ind Hyg Assoc J 50:646–50
  • Jerrett M, Burnett RT, Beckerman BS, et al. (2013). Spatial analysis of air pollution and mortality in California. Am J Respir Crit Care Med 188:593–9
  • Lund AK, Knuckles TL, Akata CO, et al. (2007). Gasoline exhaust emissions induce vascular remodeling pathways involved in atherosclerosis. Toxicol Sci 95:485–94
  • Mauderly JL, Barrett EG, Day KC, et al. (2014). The National Environmental Respiratory Center (NERC) experiment in multi-pollutant air quality health research: II. Comparison of responses to diesel and gasoline engine exhausts, hardwood smoke, and simulated downwind coal combustion emissions. Inhal Toxicol 26:674–90.
  • Mauderly JL, Barrett EG, Gigliotti AP, et al. (2011). Health effects of subchronic inhalation exposure to simulated “downwind” coal combustion emissions. Inhal Toxicol 23:349–62
  • Mauderly JL, Burnett RT, Castillejos M, et al. (2010). Commentary: is the air pollution health research community prepared to support a multipollutant air quality management framework? Inhal Toxicol 22:1–19
  • Mauderly JL, Samet JM. (2009). Is there evidence for synergy among air pollutants in causing health effects? Environ Health Perspect 117:1–6
  • Mauderly JL. (2014). The National Environmental Respiratory Center (NERC) experiment in multi-pollutant air quality health research: I. Background, experimental strategy, and critique. Inhal Toxicol 26:666–73.
  • McDonald JD, Barr EB, White RK, et al. (2004). Generation and characterization of four dilutions of diesel engine exhaust for a subchronic inhalation study. Environ Sci Technol 38:2513–22
  • McDonald JD, Barr EB, White RK, et al. (2008). Generation and characterization of gasoline engine exhaust inhalation exposure atmospheres. Inhal Toxicol 20:1157–68
  • McDonald JD, White RK, Barr EB, et al. (2006). Generation and characterization of hardwood smoke inhalation exposure atmospheres. Aerosol Sci Technol 40:573–84
  • McDonald JD, White RK, Holmes T, et al. (2012). Simulated downwind coal emissions for laboratory inhalation exposure atmospheres. Inhal Toxicol 24:310–19
  • Meinguet J. (1979). Multivariate interpolation of arbitrary points made simple. J Appl Math Phys (ZAMP) 5:439–68
  • Metzger KB, Tolbert PE, Klein M, et al. (2004). Ambient air pollution and cardiovascular emergency department visits. Epidemiology 15:46–56
  • Musselman NP, Groff WA, Yevich PP, et al. (1959). Continuous exposure of laboratory animals to low concentrations of carbon monoxide. Aerospace Med 30:524–9
  • Peel JL, Metzger KB, Klein M, et al. (2007). Ambient air pollution and cardiovascular emergency department visits in potentially sensitive groups. Am J Epidemiol 165:625–33
  • Penney DG, Bishop PA. (1978). Hematologic changes in the rat during and after exposure to carbon monoxide. J Environ Pathol Toxicol 2:407–15
  • Reed MD, Barrett EG, Campen MJ, et al. (2008). Health effects of subchronic inhalation exposure to gasoline engine emissions. Inhal Toxicol 20:1125–43
  • Reed MD, Blair LF, Burling K, et al. (2006b). Health effects of subchronic exposure to diesel-water-methanol emulsion emission. Toxicol Ind Health 22:65–85
  • Reed MD, Campen MJ, Gigliotti AP, et al. (2006a). Health effects of subchronic exposure to environmental levels of hardwood smoke. Inhal Toxicol 18:523–39
  • Reed MD, Gigliotti AP, McDonald JD, et al. (2004). Health effects of subchronic exposure to environmental levels of diesel exhaust. Inhal Toxicol 16:177–93
  • Sarnat JA, Marmur A, Klein M, et al. (2008). Fine particle sources and cardiorespiratory morbidity: and application of chemical mass balance and factor analytical source apportionment methods. Environ Health Perspect 116:459–66
  • Seagrave JC, McDonald JD, Reed MD, et al. (2005). Responses to subchronic inhalation of low concentrations of diesel exhaust and hardwood smoke measured in rat bronchoalveolar lavage fluid. Inhal Toxicol 17:657–70
  • Seilkop SK, Campen MJ, Lund AK, et al. (2012). Identification of chemical components of combustion emissions that affect pro-atherosclerotic vascular responses in mice. Inhal Toxicol 24:270–87
  • Stupfel M, Bouley G. (1970). Physiological and biochemical effects on rats and mice exposed to small concentrations of carbon monoxide for long periods. Ann NY Acad Sci 174:342–68
  • Suh HH, Zanobetti A, Schwartz J, Coull BA. (2011). Chemical properties of air pollutants and cause-specific hospital admissions among the elderly in Atlanta, Georgia. Environ Health Perspect 119:1421–8
  • Vedal S, Campen ML, McDonald JD, et al. (2013). National particle component toxicity (NPACT) initiative report on cardiovascular effects. Research Report 178. Boston: Health Effect Institute
  • Wahba G, Wendelberger J. (1980). Some new mathematical methods for variational objective analysis using splines and cross validation. Monthly Weather Rev 108:1122–45
  • Zora JE, Sarnat SE, Raysoni AU, et al. (2013). Associations between urban air pollution and pediatric asthma control in El Paso, Texas. Sci Total Environ 448:56–65

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